EP1969337A4 - Multiplex-testverfahren unter verwendung magnetischer und nichtmagnetischer partikel - Google Patents
Multiplex-testverfahren unter verwendung magnetischer und nichtmagnetischer partikelInfo
- Publication number
- EP1969337A4 EP1969337A4 EP06845948A EP06845948A EP1969337A4 EP 1969337 A4 EP1969337 A4 EP 1969337A4 EP 06845948 A EP06845948 A EP 06845948A EP 06845948 A EP06845948 A EP 06845948A EP 1969337 A4 EP1969337 A4 EP 1969337A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- magnetic
- multiplex assays
- magnetic particles
- particles
- multiplex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000006249 magnetic particle Substances 0.000 title 1
- 238000007837 multiplex assay Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00564—Handling or washing solid phase elements, e.g. beads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75349305P | 2005-12-23 | 2005-12-23 | |
| US75358305P | 2005-12-23 | 2005-12-23 | |
| PCT/US2006/048797 WO2007075891A2 (en) | 2005-12-23 | 2006-12-22 | Multiplex assays using magnetic and non-magnetic particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1969337A2 EP1969337A2 (de) | 2008-09-17 |
| EP1969337A4 true EP1969337A4 (de) | 2010-01-27 |
Family
ID=38218611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP06845948A Withdrawn EP1969337A4 (de) | 2005-12-23 | 2006-12-22 | Multiplex-testverfahren unter verwendung magnetischer und nichtmagnetischer partikel |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20070166835A1 (de) |
| EP (1) | EP1969337A4 (de) |
| WO (1) | WO2007075891A2 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4667874B2 (ja) * | 2002-12-26 | 2011-04-13 | メソ スケール テクノロジーズ エルエルシー | バイオマーカーを抽出するための方法、組成物およびキット |
| US20080075636A1 (en) * | 2006-09-22 | 2008-03-27 | Luminex Corporation | Assay Preparation Systems |
| CN101868286A (zh) | 2007-09-20 | 2010-10-20 | 马格雷股份有限公司 | 采用磁性传感器进行的分析物检测 |
| JP2011511273A (ja) * | 2008-01-25 | 2011-04-07 | ルミネックス コーポレーション | ソレノイド・アクチュエータ |
| GB0815212D0 (en) * | 2008-08-20 | 2008-09-24 | Roar Particles Ltd | Identification of sample components |
| US20100129786A1 (en) * | 2008-11-21 | 2010-05-27 | General Electric Company | Agents and methods for spectrometric analysis |
| KR20100122366A (ko) * | 2009-05-12 | 2010-11-22 | 삼성전자주식회사 | 핵산 서열의 결정을 위한 자성 입자 및 이를 이용한 핵산 서열 결정 방법 |
| US8063636B2 (en) | 2009-05-29 | 2011-11-22 | The Invention Science Fund I, Llc | Systems, devices, methods, and compositions including targeted ferromagnetic structures |
| US8106655B2 (en) | 2009-05-29 | 2012-01-31 | The Invention Science Fund I, Llc | Multiplex imaging systems, devices, methods, and compositions including ferromagnetic structures |
| US8058872B2 (en) | 2009-05-29 | 2011-11-15 | The Invention Science Fund I, Llc | Systems, devices, methods, and compositions including functionalized ferromagnetic structures |
| US8154285B1 (en) | 2009-05-29 | 2012-04-10 | The Invention Science Fund I, Llc | Non-external static magnetic field imaging systems, devices, methods, and compositions |
| US20100330703A1 (en) * | 2009-06-24 | 2010-12-30 | Seventh Sense Biosystems, Inc. | Assays involving colorimetric and other signaling |
| WO2011026030A1 (en) * | 2009-08-31 | 2011-03-03 | Mbio Diagnostics Corporation | Integrated sample preparation and analyte detection |
| JP5623888B2 (ja) | 2009-12-10 | 2014-11-12 | エフ.ホフマン−ラ ロシュアーゲーF.Hoffmann−La Roche Aktiengesellschaft | 分析対象物を分離して検出する方法 |
| US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
| US9476812B2 (en) | 2010-04-21 | 2016-10-25 | Dna Electronics, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
| US8841104B2 (en) | 2010-04-21 | 2014-09-23 | Nanomr, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
| US8900527B2 (en) | 2010-06-29 | 2014-12-02 | Roche Molecular Systems Inc. | Pipetting device with independently movable pipette units |
| JP6101215B2 (ja) | 2011-03-09 | 2017-03-22 | マグアレイ,インコーポレイテッド | サンプル中の分析対象物に対するハイスループット検出を行うシステム及び方法 |
| US20120288849A1 (en) * | 2011-03-15 | 2012-11-15 | The Board of Trustees of the Leland Stanford, Junior, University | Method and system for robust and sensitive analysis of bead-based assays |
| CN103207272A (zh) * | 2012-01-13 | 2013-07-17 | 中华人民共和国上海出入境检验检疫局 | 同时检测水产品中醋酸甲羟孕酮和己烯雌酚的方法 |
| ES2678211T3 (es) | 2012-03-27 | 2018-08-09 | Ventana Medical Systems, Inc. | Conjugados de señalización y procedimientos de uso |
| DE102012107651A1 (de) * | 2012-08-21 | 2014-02-27 | Astrium Gmbh | Verfahren zur Durchführung einer biochemischen Analyse, insbesondere im Weltraum |
| JP2016507727A (ja) * | 2012-12-11 | 2016-03-10 | ザ ガバニング カウンシル オブ ザ ユニヴァーシティー オブ トロントThe Governing Council Of The University Of Toronto | 無線通信デバイスをベースとする検出システム |
| US9551704B2 (en) | 2012-12-19 | 2017-01-24 | Dna Electronics, Inc. | Target detection |
| US9804069B2 (en) | 2012-12-19 | 2017-10-31 | Dnae Group Holdings Limited | Methods for degrading nucleic acid |
| US9995742B2 (en) | 2012-12-19 | 2018-06-12 | Dnae Group Holdings Limited | Sample entry |
| US10000557B2 (en) | 2012-12-19 | 2018-06-19 | Dnae Group Holdings Limited | Methods for raising antibodies |
| US9434940B2 (en) * | 2012-12-19 | 2016-09-06 | Dna Electronics, Inc. | Methods for universal target capture |
| US9599610B2 (en) | 2012-12-19 | 2017-03-21 | Dnae Group Holdings Limited | Target capture system |
| US20140194315A1 (en) * | 2013-01-08 | 2014-07-10 | Albert Einstein College Of Medicine Of Yeshiva University | Methods and compositions for rapid functional analysis of gene variants |
| CA2937975A1 (en) * | 2014-01-27 | 2015-07-30 | Brevitest Technologies, Llc | Discontinuous fluidic systems for point-of-care analyte measurement |
| US10195609B2 (en) * | 2016-10-25 | 2019-02-05 | Fannin Partners, LLC | Assay wells with hydrogel as a well-contents separator and a pigment-based temperature indicator |
| ES2599056B2 (es) * | 2015-07-31 | 2017-07-07 | Pablo ALBERTOS SÁNCHEZ | Dispositivo para ensayar una muestra de células |
| US10329554B2 (en) | 2016-11-07 | 2019-06-25 | Wavesense, Inc. | System and method for sequestering substances in bulk liquids |
| IL298245A (en) * | 2020-05-18 | 2023-01-01 | Truvian Sciences Inc | Continuous scanning optical assembly and method of use thereof |
| EP3945318B1 (de) * | 2020-07-31 | 2023-12-20 | Synlab Holding Deutschland GmbH | Verfahren zur bündelung von proben für analytnachweis |
| US20240295549A1 (en) * | 2020-08-07 | 2024-09-05 | Vital Biosciences Inc. | Multiplexed analyte detection |
| EP4295150A4 (de) | 2021-02-17 | 2025-01-29 | Morgan and Mendel Genomics, Inc. | Verfahren und zusammensetzungen zur diagnose, mangel in der reparatur von keimbahnfehlanpassungen, lynch-syndrom und beurteilung des keimbahnrisikos von krebs |
| EP4326335A1 (de) | 2021-04-23 | 2024-02-28 | Forschungsverbund Berlin E.V. | Thiolkonjugation mit ungesättigten phosphor(v)-verbindungen |
| WO2023198337A1 (en) | 2022-04-12 | 2023-10-19 | Glycanostics S.R.O. | Means and methods for high-throughput glycoprofiling of proteins |
| USD1116151S1 (en) | 2023-05-03 | 2026-03-03 | Truvian Sciences, Inc. | Monolayer |
| GB2633685A (en) * | 2023-07-20 | 2025-03-19 | Plexbio Co Ltd | Devices and systems for automated assays and uses thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020164659A1 (en) * | 2000-11-30 | 2002-11-07 | Rao Galla Chandra | Analytical methods and compositions |
| GB2410952A (en) * | 2004-02-12 | 2005-08-17 | Bruker Daltonic Gmbh | Mass spectrometry of proteins |
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| US4499052A (en) * | 1982-08-30 | 1985-02-12 | Becton, Dickinson And Company | Apparatus for distinguishing multiple subpopulations of cells |
| SE458968B (sv) * | 1987-06-16 | 1989-05-22 | Wallac Oy | Biospecifikt analysfoerfarande foer flera analyter i vilket ingaar partikelraekning och maerkning med fluorescerande maerksubstanser |
| US5196306A (en) * | 1989-03-29 | 1993-03-23 | E. I. Du Pont De Nemours And Company | Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system |
| FI932866A0 (fi) * | 1993-06-21 | 1993-06-21 | Labsystems Oy | Separeringsfoerfarande |
| US5670314A (en) * | 1994-02-22 | 1997-09-23 | Regents Of The University Of California | Genetic alterations that correlate with lung carcinomas |
| US5830645A (en) * | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US5635351A (en) * | 1995-03-14 | 1997-06-03 | The Regents Of The University Of California | Genetic gain and loss in gliomas |
| WO1997014028A2 (en) * | 1995-10-11 | 1997-04-17 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| US5981180A (en) * | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
| US6297062B1 (en) * | 1996-03-07 | 2001-10-02 | Bio-Magnetics Ltd. | Separation by magnetic particles |
| US6277563B1 (en) * | 1997-01-16 | 2001-08-21 | The Regents Of The University Of California | Genetic alterations associated with cancer |
| DE69812329T2 (de) * | 1997-11-18 | 2004-02-12 | Bio-Rad Laboratories, Inc., Hercules | Multiplex-zufluss-immunotest mit magnetischen teilchen als festphase |
| FI102906B1 (fi) * | 1998-02-23 | 1999-03-15 | Bio Nobile Oy | Menetelmä ja väline aineen siirtämiseksi |
| US6110618A (en) * | 1998-02-27 | 2000-08-29 | Motorola, Inc. | Battery cell housing |
| EP1204869B1 (de) * | 1999-08-17 | 2008-10-22 | Luminex Corporation | Verfahren zur analyse einer mehrzahl von proben verschiedenen ursprungs auf einen analyten |
| WO2001078087A2 (en) * | 2000-04-06 | 2001-10-18 | Luminex Corporation | Magnetically-responsive microspheres |
| US20030186465A1 (en) * | 2001-11-27 | 2003-10-02 | Kraus Robert H. | Apparatus used in identification, sorting and collection methods using magnetic microspheres and magnetic microsphere kits |
| US20040219695A1 (en) * | 2002-01-19 | 2004-11-04 | Fox John Stewart | High sensitivity detection of and manipulation of biomolecules and cells with magnetic particles |
| US20040126875A1 (en) * | 2002-09-12 | 2004-07-01 | Putnam Martin A. | Assay stick |
| US7190522B2 (en) * | 2002-09-12 | 2007-03-13 | Cyvera Corporation | Chemical synthesis using diffraction grating-based encoded optical elements |
| US7399643B2 (en) * | 2002-09-12 | 2008-07-15 | Cyvera Corporation | Method and apparatus for aligning microbeads in order to interrogate the same |
| WO2004019277A1 (en) * | 2002-08-20 | 2004-03-04 | Cyvera Corporation | Diffraction grating-based encoded micro-particles for multiplexed experiments |
| EP1540591A1 (de) * | 2002-09-12 | 2005-06-15 | Cyvera Corporation | Mit hilfe eines beugungsgitters kodierte mikropartikeln für multiplex-experimente |
| US7092160B2 (en) * | 2002-09-12 | 2006-08-15 | Illumina, Inc. | Method of manufacturing of diffraction grating-based optical identification element |
| CA2499037A1 (en) * | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Method and apparatus for labelling using diffraction grating-based encoded optical identification elements |
-
2006
- 2006-12-22 EP EP06845948A patent/EP1969337A4/de not_active Withdrawn
- 2006-12-22 WO PCT/US2006/048797 patent/WO2007075891A2/en not_active Ceased
- 2006-12-22 US US11/615,731 patent/US20070166835A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020164659A1 (en) * | 2000-11-30 | 2002-11-07 | Rao Galla Chandra | Analytical methods and compositions |
| GB2410952A (en) * | 2004-02-12 | 2005-08-17 | Bruker Daltonic Gmbh | Mass spectrometry of proteins |
Non-Patent Citations (1)
| Title |
|---|
| MOROZOV V N ET AL: "Active bead-linked immunoassay on protein microarrays", ANALYTICA CHIMICA ACTA, ELSEVIER, AMSTERDAM, NL, vol. 564, no. 1, 30 March 2006 (2006-03-30), pages 40 - 52, XP025048039, ISSN: 0003-2670, [retrieved on 20060330] * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007075891A2 (en) | 2007-07-05 |
| EP1969337A2 (de) | 2008-09-17 |
| WO2007075891A3 (en) | 2008-02-28 |
| US20070166835A1 (en) | 2007-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20080710 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20100104 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20060101ALI20091223BHEP Ipc: G01N 33/553 20060101ALI20091223BHEP Ipc: G01N 1/00 20060101AFI20080715BHEP |
|
| 17Q | First examination report despatched |
Effective date: 20100511 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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| 18D | Application deemed to be withdrawn |
Effective date: 20110701 |