EP1978988A4 - Regulation de jonctions communicantes a l aide de peptides - Google Patents

Regulation de jonctions communicantes a l aide de peptides

Info

Publication number
EP1978988A4
EP1978988A4 EP07718080A EP07718080A EP1978988A4 EP 1978988 A4 EP1978988 A4 EP 1978988A4 EP 07718080 A EP07718080 A EP 07718080A EP 07718080 A EP07718080 A EP 07718080A EP 1978988 A4 EP1978988 A4 EP 1978988A4
Authority
EP
European Patent Office
Prior art keywords
peptides
regulation
communicating junctions
junctions
communicating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07718080A
Other languages
German (de)
English (en)
Other versions
EP1978988A2 (fr
Inventor
Mario Delmar
Steven M Taffet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of the State University of New York
Original Assignee
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of the State University of New York filed Critical Research Foundation of the State University of New York
Publication of EP1978988A2 publication Critical patent/EP1978988A2/fr
Publication of EP1978988A4 publication Critical patent/EP1978988A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP07718080A 2006-01-13 2007-01-16 Regulation de jonctions communicantes a l aide de peptides Withdrawn EP1978988A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75888606P 2006-01-13 2006-01-13
PCT/US2007/060584 WO2007084895A2 (fr) 2006-01-13 2007-01-16 Regulation de jonctions communicantes a l’aide de peptides

Publications (2)

Publication Number Publication Date
EP1978988A2 EP1978988A2 (fr) 2008-10-15
EP1978988A4 true EP1978988A4 (fr) 2009-11-04

Family

ID=38288369

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07718080A Withdrawn EP1978988A4 (fr) 2006-01-13 2007-01-16 Regulation de jonctions communicantes a l aide de peptides

Country Status (2)

Country Link
EP (1) EP1978988A4 (fr)
WO (1) WO2007084895A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090075291A1 (en) * 2006-01-13 2009-03-19 The Research Foundation Of State University Of New York Peptide-based regulation of gap junctions
US8404644B2 (en) 2007-09-07 2013-03-26 Meat & Livestock Australia Limited Agents with angiogenic and wound healing activity
EP2260859A1 (fr) * 2009-06-12 2010-12-15 Zealand Pharma A/S Composés agissant en tant que modulateurs de jonction communicante de peptide et leurs utilisations

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009012224A2 (fr) * 2007-07-13 2009-01-22 The Research Foundation Of State University Of New York Régulation à base de peptides à jonction lacunaire

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
JP2000026315A (ja) * 1998-07-09 2000-01-25 Dai Ichi Seiyaku Co Ltd カルシウムチャンネル活性化剤の評価方法
WO2005079849A2 (fr) * 2004-02-25 2005-09-01 Zgene A/S Composes pour la traitement ameliore du cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009012224A2 (fr) * 2007-07-13 2009-01-22 The Research Foundation Of State University Of New York Régulation à base de peptides à jonction lacunaire

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
COOMBS W ET AL: "A peptide-based strategy to modify Cx43CT structure and Cx43 channel function", MOLECULAR BIOLOGY OF THE CELL, BETHESDA, MD, US, vol. 15, no. Suppl. S, 1 November 2004 (2004-11-01), pages 308A - 309A, XP008110588, ISSN: 1059-1524 *
DUFFY HEATHER S ET AL: "pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domains", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM, US, vol. 277, no. 39, 27 September 2002 (2002-09-27), pages 36706 - 36714, XP009108338, ISSN: 0021-9258 *
KWAK BRENDA R ET AL: "Selective inhibition of gap junction channel activity by synthetic peptides", JOURNAL OF PHYSIOLOGY, WILEY-BLACKWELL PUBLISHING LTD, GB, vol. 516, no. 3, 1 May 1999 (1999-05-01), pages 679 - 685, XP009108312, ISSN: 0022-3751 *
SHIBAYAMA JUNKO ET AL: "Identification of a novel peptide that interferes with the chemical regulation of connexin43", CIRCULATION RESEARCH, GRUNE AND STRATTON, BALTIMORE, US, vol. 98, no. 11, 1 June 2006 (2006-06-01), pages 1365 - 1372, XP009115918, ISSN: 0009-7330 *
TAFFET ET AL: "Manipulation of gap junction proteins: effect on cellular coupling and impulse propagation", JOURNAL OF ELECTROCARDIOLOGY, ELSEVIER SCIENCE, XX, vol. 38, no. 4, 1 October 2005 (2005-10-01), pages 51, XP005110123, ISSN: 0022-0736 *

Also Published As

Publication number Publication date
EP1978988A2 (fr) 2008-10-15
WO2007084895A3 (fr) 2008-08-14
WO2007084895A2 (fr) 2007-07-26

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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A4 Supplementary search report drawn up and despatched

Effective date: 20091001

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 7/08 20060101ALI20090925BHEP

Ipc: A61K 38/10 20060101AFI20070904BHEP

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Effective date: 20100708

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Effective date: 20110119