EP1996937A4 - Genetic packages and uses thereof - Google Patents

Genetic packages and uses thereof

Info

Publication number
EP1996937A4
EP1996937A4 EP07752549A EP07752549A EP1996937A4 EP 1996937 A4 EP1996937 A4 EP 1996937A4 EP 07752549 A EP07752549 A EP 07752549A EP 07752549 A EP07752549 A EP 07752549A EP 1996937 A4 EP1996937 A4 EP 1996937A4
Authority
EP
European Patent Office
Prior art keywords
genetic packages
packages
genetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07752549A
Other languages
German (de)
French (fr)
Other versions
EP1996937A2 (en
Inventor
Volker Schellenberger
Willem P Stemmer
Chia-Wei Wang
Michael D Scholle
Mikhail Popkov
Nathaniel C Gordon
Andreas Crameri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amunix Pharmaceuticals Inc
Original Assignee
Amunix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38475542&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1996937(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US11/528,927 external-priority patent/US20070191272A1/en
Application filed by Amunix Inc filed Critical Amunix Inc
Publication of EP1996937A2 publication Critical patent/EP1996937A2/en
Publication of EP1996937A4 publication Critical patent/EP1996937A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP07752549A 2006-03-06 2007-03-06 Genetic packages and uses thereof Withdrawn EP1996937A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US74341006P 2006-03-06 2006-03-06
US74362206P 2006-03-21 2006-03-21
US11/528,927 US20070191272A1 (en) 2005-09-27 2006-09-27 Proteinaceous pharmaceuticals and uses thereof
US11/528,950 US20070212703A1 (en) 2005-09-27 2006-09-27 Proteinaceous pharmaceuticals and uses thereof
PCT/US2007/005857 WO2007103455A2 (en) 2006-03-06 2007-03-06 Genetic packages and uses thereof

Publications (2)

Publication Number Publication Date
EP1996937A2 EP1996937A2 (en) 2008-12-03
EP1996937A4 true EP1996937A4 (en) 2009-04-08

Family

ID=38475542

Family Applications (3)

Application Number Title Priority Date Filing Date
EP07752549A Withdrawn EP1996937A4 (en) 2006-03-06 2007-03-06 Genetic packages and uses thereof
EP20140189047 Ceased EP2863222A1 (en) 2006-03-06 2007-03-06 Unstructured recombinant polymers and uses thereof
EP07752636.6A Active EP1996220B2 (en) 2005-09-27 2007-03-06 Unstructured recombinant polymers and uses thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
EP20140189047 Ceased EP2863222A1 (en) 2006-03-06 2007-03-06 Unstructured recombinant polymers and uses thereof
EP07752636.6A Active EP1996220B2 (en) 2005-09-27 2007-03-06 Unstructured recombinant polymers and uses thereof

Country Status (6)

Country Link
EP (3) EP1996937A4 (en)
AU (2) AU2007223888A1 (en)
CA (1) CA2644712C (en)
DK (1) DK2402754T4 (en)
SI (1) SI2402754T2 (en)
WO (2) WO2007103515A2 (en)

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US7846445B2 (en) 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
US7855279B2 (en) 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
CN101384272B (en) 2005-12-20 2013-05-01 杜克大学 Methods and compositions for delivering active agents with enhanced pharmacological properties
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
EP1996937A4 (en) 2006-03-06 2009-04-08 Amunix Inc Genetic packages and uses thereof
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
ATE502114T1 (en) 2007-06-21 2011-04-15 Univ Muenchen Tech BIOLOGICALLY ACTIVE PROTEINS WITH INCREASED IN-VIVO AND/OR IN-VITRO STABILITY
US8933197B2 (en) * 2007-08-15 2015-01-13 Amunix Operating Inc. Compositions comprising modified biologically active polypeptides
EP3412300A1 (en) 2008-06-27 2018-12-12 Duke University Therapeutic agents comprising elastin-like peptides
BRPI0920209A2 (en) 2008-10-15 2015-12-22 Angiochem Inc conjugates of glp-1 agonists and their uses
CA2745524C (en) 2008-12-05 2020-06-09 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
AU2014206217B2 (en) * 2009-02-03 2015-09-17 Amunix Pharmaceuticals, Inc. Extended recombinant polypeptides and compositions comprising same
AU2015218510B2 (en) * 2009-02-03 2016-11-10 Amunix Pharmaceuticals, Inc. Extended recombinant polypeptides and compositions comprising same
CA2748314C (en) 2009-02-03 2018-10-02 Amunix Operating Inc. Extended recombinant polypeptides and compositions comprising same
US8703717B2 (en) 2009-02-03 2014-04-22 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
US8680050B2 (en) 2009-02-03 2014-03-25 Amunix Operating Inc. Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
WO2010121379A1 (en) 2009-04-20 2010-10-28 Angiochem Inc Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog
SI2440241T1 (en) * 2009-06-08 2017-11-30 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
US9849188B2 (en) 2009-06-08 2017-12-26 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
JP5839597B2 (en) 2009-06-08 2016-01-06 アムニクス オペレーティング インコーポレイテッド Glucose-regulating polypeptide and methods for making and using the same
AU2010268726A1 (en) * 2009-07-02 2012-01-19 Angiochem Inc. Multimeric peptide conjugates and uses thereof
AU2010290131C1 (en) * 2009-08-24 2015-12-03 Amunix Operating Inc. Coagulation factor VII compositions and methods of making and using same
CN102164949B (en) * 2009-11-19 2013-10-23 浙江大学 Novel recombinant fusion protein
PL3326643T3 (en) 2009-12-06 2021-10-25 Bioverativ Therapeutics Inc. Factor viii-fc chimeric and hybrid polypeptides, and methods of use thereof
WO2011123830A2 (en) * 2010-04-02 2011-10-06 Amunix Operating Inc. Alpha 1-antitrypsin compositions and methods of making and using same
EP2552967A4 (en) * 2010-04-02 2014-10-08 Amunix Operating Inc Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same
TWI510246B (en) 2010-04-30 2015-12-01 Molecular Partners Ag Modified binding proteins inhibiting the vegf-a receptor interaction
WO2011144756A1 (en) 2010-05-21 2011-11-24 Xl-Protein Gmbh Biosynthetic proline/alanine random coil polypeptides and their uses
ES2486321T3 (en) 2010-06-18 2014-08-18 Xiberscience Gmbh Peptides as active agents to stabilize biological barriers
UA126265C2 (en) 2010-07-09 2022-09-14 Байовератів Терапьютікс Інк. Factor ix polypeptide and method of its use
DK2643349T3 (en) 2010-11-26 2019-11-25 Molecular Partners Ag DESIGNED REPEAT PROTEINS BINDING TO SERUM ALBUMIN
CA2838833A1 (en) 2011-06-10 2012-12-13 Biogen Idec Ma Inc. Pro-coagulant compounds and methods of use thereof
CN103796670A (en) 2011-07-08 2014-05-14 比奥根艾迪克依蒙菲利亚公司 Factor VIII chimeric and hybrid polypeptides and methods of use thereof
WO2013016454A1 (en) 2011-07-25 2013-01-31 Biogen Idec Hemophilia Inc. Assays to monitor bleeding disorders
DK2804623T3 (en) * 2012-01-12 2019-11-11 Bioverativ Therapeutics Inc CHEMICAL FACTOR VIII POLYPEPTIDES AND APPLICATIONS THEREOF
CA2864126A1 (en) 2012-02-15 2013-08-22 Biogen Idec Ma Inc. Recombinant factor viii proteins
BR112014020694A2 (en) 2012-02-15 2018-05-08 Amunix Operating Inc. factor viii fusion protein comprising extended recombinant polypeptide (xten) fusion factor polypeptide and its method of manufacture, nucleic acid, vectors, host cell, as well as pharmaceutical composition and its use in the treatment of coagulopathy, bleeding episode and hemophilia a
CN117462693A (en) 2012-02-27 2024-01-30 阿穆尼克斯运营公司 XTEN conjugate compositions and methods of making the same
HUE046134T2 (en) 2012-05-07 2020-02-28 Allergan Inc Method of treating amd in patients refractory to anti-vegf therapy
CN108524919A (en) 2012-05-17 2018-09-14 延伸生物科学股份有限公司 Carriers for Improved Drug Delivery
CA2877584A1 (en) 2012-06-28 2014-01-03 Molecular Partners Ag Designed ankyrin repeat proteins binding to platelet-derived growth factor
EP3404105A1 (en) 2012-07-06 2018-11-21 Bioverativ Therapeutics Inc. Cell line expressing single chain factor viii polypeptides and uses thereof
HRP20200007T1 (en) 2012-07-11 2020-03-20 Bioverativ Therapeutics Inc. Factor viii complex with xten and von willebrand factor protein, and uses thereof
TWI750197B (en) 2012-09-25 2021-12-21 美商百歐維拉提夫治療公司 Methods of using fix polypeptides
EP2738180A1 (en) 2012-11-30 2014-06-04 Molecular Partners AG Binding proteins comprising at least two binding domains against HER2.
AR095527A1 (en) 2013-03-15 2015-10-21 Biogen Idec Inc FC-FACTOR IX POLYPEPTIDE FORMULATIONS IX
WO2015022326A1 (en) 2013-08-12 2015-02-19 Xiber Science Gmbh Peptides as active agents for treating primary graft dysfunction
US10548953B2 (en) 2013-08-14 2020-02-04 Bioverativ Therapeutics Inc. Factor VIII-XTEN fusions and uses thereof
CA2927012A1 (en) 2013-11-05 2015-05-14 Allergan, Inc. Method of treating conditions of the eye with an anti-vegf darpin
US10584147B2 (en) 2013-11-08 2020-03-10 Biovertiv Therapeutics Inc. Procoagulant fusion compound
AU2015204646B2 (en) 2014-01-10 2020-08-27 Bioverativ Therapeutics Inc. Factor VIII chimeric proteins and uses thereof
PL3157552T3 (en) 2014-06-18 2020-05-18 Albert Einstein College Of Medicine SYNTAC POLYPEPTIDES AND THEIR USES
US9789197B2 (en) 2014-10-22 2017-10-17 Extend Biosciences, Inc. RNAi vitamin D conjugates
WO2016065052A1 (en) 2014-10-22 2016-04-28 Extend Biosciences, Inc. Insulin vitamin d conjugates
US9585934B2 (en) 2014-10-22 2017-03-07 Extend Biosciences, Inc. Therapeutic vitamin D conjugates
AU2016240220B2 (en) 2015-04-02 2019-11-21 Molecular Partners Ag Designed ankyrin repeat domains with binding specificity for serum albumin
JP6983075B2 (en) 2015-06-02 2021-12-17 ノヴォ ノルディスク アー／エス Insulin with polar recombination extension
DK3307326T3 (en) 2015-06-15 2020-10-19 Angiochem Inc METHODS FOR THE TREATMENT OF LEPTOMENINGAL CARCINOMATOSIS
BR112018002150A2 (en) 2015-08-03 2018-09-18 Bioverativ Therapeutics Inc factor ix fusion proteins and methods of manufacturing and using them
IL319047A (en) 2015-08-28 2025-04-01 Amunix Operating Inc Chimeric polypeptide assembly and methods of making and using the same
CN108136043B (en) 2015-10-01 2022-09-06 诺和诺德股份有限公司 Protein conjugates
CA3019005A1 (en) 2016-05-18 2017-11-23 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
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IL319473A (en) 2016-12-02 2025-05-01 Bioverativ Therapeutics Inc Methods of treating hemophilic arthropathy using chimeric clotting factors
CN116970059A (en) 2016-12-22 2023-10-31 库尔生物制药有限公司 T cell modulating multimeric polypeptides and methods of use thereof
US11851471B2 (en) 2017-01-09 2023-12-26 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
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CN110505885A (en) 2017-04-05 2019-11-26 诺和诺德股份有限公司 Oligomer-extended insulin-Fc conjugates
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WO2019201855A1 (en) * 2018-04-16 2019-10-24 Swedish Orphan Biovitrum Ab (Publ) Lysosomal fusion protein
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WO2022123459A1 (en) 2020-12-11 2022-06-16 Friedrich Miescher Institute For Biomedical Research Hdac6 binding proteins and their anti-viral use
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CN115083016A (en) * 2022-06-09 2022-09-20 广州紫为云科技有限公司 Monocular camera-based small-target-oriented hand space interaction method and device
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Also Published As

Publication number Publication date
AU2007223855A1 (en) 2007-09-13
WO2007103515A2 (en) 2007-09-13
SI2402754T1 (en) 2015-02-27
WO2007103515A3 (en) 2008-04-03
EP1996220B1 (en) 2013-05-08
EP1996220A2 (en) 2008-12-03
EP1996937A2 (en) 2008-12-03
WO2007103455A2 (en) 2007-09-13
DK2402754T4 (en) 2023-08-28
EP1996220A4 (en) 2009-04-29
WO2007103455A3 (en) 2007-11-29
AU2007223855B2 (en) 2013-05-16
EP1996220B2 (en) 2023-08-16
DK2402754T3 (en) 2015-01-12
CA2644712C (en) 2016-09-13
CA2644712A1 (en) 2007-09-13
SI2402754T2 (en) 2023-09-29
AU2007223888A1 (en) 2007-09-13
EP2863222A1 (en) 2015-04-22

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