EP2011869A4 - Neuer anti-cd98-antikörper - Google Patents

Neuer anti-cd98-antikörper

Info

Publication number: EP2011869A4
Authority: EP; European Patent Office
Prior art keywords: antibody; new anti; new
Prior art date: 2006-04-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP07741116A

Other languages

English (en)

French (fr)

Other versions

EP2011869B1 (de

EP2011869A1 (de

Inventor

Tomoyuki Tahara

Yoshikatsu Kanai

Hitoshi Endou

Shiro Kataoka

Kazumasa Hasegawa

Tetsuya Yoshino

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kyowa Kirin Co Ltd

Original Assignee

Kirin Holdings Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-06

Filing date

2007-04-05

Publication date

2010-03-17

2007-04-05 Application filed by Kirin Holdings Co Ltd filed Critical Kirin Holdings Co Ltd

2007-04-05 Priority to PL07741116T priority Critical patent/PL2011869T3/pl

2007-04-05 Priority to EP12171303A priority patent/EP2527437A1/de

2009-01-07 Publication of EP2011869A1 publication Critical patent/EP2011869A1/de

2010-03-17 Publication of EP2011869A4 publication Critical patent/EP2011869A4/de

2014-06-11 Application granted granted Critical

2014-06-11 Publication of EP2011869B1 publication Critical patent/EP2011869B1/de

Status Not-in-force legal-status Critical Current

2027-04-05 Anticipated expiration legal-status Critical

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Plant Pathology (AREA)
General Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

EP07741116.3A 2006-04-06 2007-04-05 Neuer anti-cd98-antikörper Not-in-force EP2011869B1 (de)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
PL07741116T PL2011869T3 (pl)	2006-04-06	2007-04-05	Nowe przeciwciało anty-CD98
EP12171303A EP2527437A1 (de)	2006-04-06	2007-04-05	Neue Anti-CD98-Antikörper

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2006105013		2006-04-06
PCT/JP2007/057680 WO2007114496A1 (ja)	2006-04-06	2007-04-05	新規抗ｃｄ９８抗体

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
EP12171303A Division-Into EP2527437A1 (de)	2006-04-06	2007-04-05	Neue Anti-CD98-Antikörper

Publications (3)

Publication Number	Publication Date
EP2011869A1 EP2011869A1 (de)	2009-01-07
EP2011869A4 true EP2011869A4 (de)	2010-03-17
EP2011869B1 EP2011869B1 (de)	2014-06-11

Family

ID=38563755

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
EP12171303A Withdrawn EP2527437A1 (de)	2006-04-06	2007-04-05	Neue Anti-CD98-Antikörper
EP07741116.3A Not-in-force EP2011869B1 (de)	2006-04-06	2007-04-05	Neuer anti-cd98-antikörper

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
EP12171303A Withdrawn EP2527437A1 (de)	2006-04-06	2007-04-05	Neue Anti-CD98-Antikörper

Country Status (12)

Country	Link
US (4)	US7943745B2 (de)
EP (2)	EP2527437A1 (de)
JP (2)	JP4324637B2 (de)
KR (1)	KR101370164B1 (de)
CN (2)	CN101460623B (de)
AU (1)	AU2007232706B2 (de)
CA (1)	CA2648618C (de)
ES (1)	ES2489641T3 (de)
PL (1)	PL2011869T3 (de)
PT (1)	PT2011869E (de)
TW (1)	TWI390034B (de)
WO (1)	WO2007114496A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI390034B (zh) *	2006-04-06	2013-03-21	Kyowa Hakko Kirin Co Ltd	Novel anti-CD98 antibody
GB0615662D0 (en) *	2006-08-07	2006-09-13	Affitech As	Antibody
WO2011118804A1 (ja)	2010-03-26	2011-09-29	国立大学法人徳島大学	新規抗ｃｄ９８抗体とその用途
PT2653540T (pt)	2010-12-15	2018-02-27	Kyowa Hakko Kirin Co Ltd	Processo de produção de proteínas
ES2656079T3 (es)	2010-12-15	2018-02-23	Kyowa Hakko Kirin Co., Ltd.	Procedimiento para producir proteínas
EP2698634B1 (de) *	2011-04-15	2017-11-08	J-Pharma Co., Ltd.	Biomarker für brustkrebs
JP2015501639A (ja) *	2011-11-23	2015-01-19	アイジェニカバイオセラピューティクスインコーポレイテッド	抗ｃｄ９８抗体およびその使用方法
ES2711554T3 (es) *	2012-05-22	2019-05-06	Bristol Myers Squibb Co	Anticuerpos biespecíficos contra IL-17A/F IL-23 y sus usos
CN104662153A (zh) *	2012-06-08	2015-05-27	学校法人近畿大学	针对转运体的抗体及其用途
US9650411B2 (en)	2012-08-07	2017-05-16	Kyowa Hakko Kirin Co., Ltd.	Method of purifying protein
WO2016036391A1 (en) *	2014-09-05	2016-03-10	Hewlett Packard Enterprise Development Lp	Firewall port access rule generation
EP3290051B1 (de) *	2015-04-30	2019-10-23	Toray Industries, Inc.	Pharmazeutische zusammensetzung zur behandlung oder prävention von krebs
CA2995166C (en) *	2015-08-10	2023-10-31	Osaka University	Anti-cd98 antibody
CN105385694B (zh) *	2015-11-20	2019-01-18	中国人民解放军第四军医大学	抗人cd98单克隆抗体98-3h3轻、重链可变区基因及其应用
CN105754952B (zh) *	2016-02-16	2020-07-10	中国农业科学院兰州兽医研究所	抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用
JPWO2021020474A1 (de)	2019-07-31	2021-02-04
CN117561276A (zh) *	2021-06-02	2024-02-13	华辉安健（北京）生物科技有限公司	抗cd98抗体及其应用
KR20240113514A (ko)	2021-11-30	2024-07-22	다이이찌 산쿄 가부시키가이샤	프로테아제 분해성 마스크 항체
US20260123609A1 (en) *	2021-12-17	2026-05-07	Biocytogen Jiangsu Co., Ltd.	Genetically modified non-human animal with human or chimeric cd98hc
KR20240141757A (ko)	2022-02-09	2024-09-27	다이이찌 산쿄 가부시키가이샤	환경 응답성 마스킹 항체 및 그 이용

Citations (3)

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Publication number	Priority date	Publication date	Assignee	Title
EP1111048A2 (de) *	1998-09-03	2001-06-27	Japan Science and Technology Corporation	Neutraler aminosäurentransporter und korrespondierendes gen
WO2003001884A2 (en) *	2001-06-26	2003-01-09	Trustees Of Tufts College	Targeting tumor cell antigens: antibodies useful for the diagnosis, prognosis, and treatment of cancer
WO2008017828A2 (en) *	2006-08-07	2008-02-14	Affitech As	Antibodies specific for human cd98 heavy antigen

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Publication number	Priority date	Publication date	Assignee	Title
NZ226694A (en)	1987-10-28	1994-04-27	Oncogen	Human immunoglobulin produced by recombinant dna techniques
US6001358A (en)	1995-11-07	1999-12-14	Idec Pharmaceuticals Corporation	Humanized antibodies to human gp39, compositions containing thereof
IL145941A (en) *	1999-04-28	2007-08-19	Univ Texas	Compositions and methods for cancer treatment by selectively inhibiting vegf
IL155977A0 (en)	2000-11-30	2003-12-23	Medarex Inc	Transgenic transchromosomal rodents for making human antibodies
KR20110017020A (ko) *	2002-10-17	2011-02-18	젠맵 에이/에스	Ｃｄ20에 대한 인간 모노클로날 항체
HN2004000285A (es) *	2003-08-04	2006-04-27	Pfizer Prod Inc	ANTICUERPOS DIRIGIDOS A c-MET
AR045563A1 (es) *	2003-09-10	2005-11-02	Warner Lambert Co	Anticuerpos dirigidos a m-csf
JP4606110B2 (ja)	2004-10-05	2011-01-05	日本電産サーボ株式会社	モータファン
TWI390034B (zh) *	2006-04-06	2013-03-21	Kyowa Hakko Kirin Co Ltd	Novel anti-CD98 antibody

2007
- 2007-04-04 TW TW096112176A patent/TWI390034B/zh not_active IP Right Cessation
- 2007-04-05 CN CN2007800210898A patent/CN101460623B/zh not_active Expired - Fee Related
- 2007-04-05 PL PL07741116T patent/PL2011869T3/pl unknown
- 2007-04-05 CA CA2648618A patent/CA2648618C/en not_active Expired - Fee Related
- 2007-04-05 CN CN201210135674.3A patent/CN102659947B/zh not_active Expired - Fee Related
- 2007-04-05 ES ES07741116.3T patent/ES2489641T3/es active Active
- 2007-04-05 WO PCT/JP2007/057680 patent/WO2007114496A1/ja not_active Ceased
- 2007-04-05 AU AU2007232706A patent/AU2007232706B2/en not_active Ceased
- 2007-04-05 US US12/295,991 patent/US7943745B2/en not_active Expired - Fee Related
- 2007-04-05 JP JP2008508722A patent/JP4324637B2/ja not_active Expired - Fee Related
- 2007-04-05 PT PT77411163T patent/PT2011869E/pt unknown
- 2007-04-05 EP EP12171303A patent/EP2527437A1/de not_active Withdrawn
- 2007-04-05 EP EP07741116.3A patent/EP2011869B1/de not_active Not-in-force
2008
- 2008-11-06 KR KR1020087027290A patent/KR101370164B1/ko not_active Expired - Fee Related
2009
- 2009-06-04 JP JP2009135435A patent/JP5160501B2/ja not_active Expired - Fee Related
2011
- 2011-05-12 US US13/106,280 patent/US8486402B2/en not_active Expired - Fee Related
2013
- 2013-07-12 US US13/940,640 patent/US9051374B2/en not_active Expired - Fee Related
2015
- 2015-05-04 US US14/703,354 patent/US9688770B2/en not_active Expired - Fee Related

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Publication number	Priority date	Publication date	Assignee	Title
EP1111048A2 (de) *	1998-09-03	2001-06-27	Japan Science and Technology Corporation	Neutraler aminosäurentransporter und korrespondierendes gen
WO2003001884A2 (en) *	2001-06-26	2003-01-09	Trustees Of Tufts College	Targeting tumor cell antigens: antibodies useful for the diagnosis, prognosis, and treatment of cancer
WO2008017828A2 (en) *	2006-08-07	2008-02-14	Affitech As	Antibodies specific for human cd98 heavy antigen

Non-Patent Citations (3)

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Title
KIM DO KYUNG ET AL: "Expression of L-type amino acid transporter1 (LAT1) and 4F2 heavy chain (4F2hc) in oral squamous cell carcinoma and its precusor lesions", ANTICANCER RESEARCH, vol. 24, no. 3A, May 2004 (2004-05-01), pages 1671 - 1675, XP009129232, ISSN: 0250-7005 *
NAWASHIRO HIROSHI ET AL: "The role of CD98 in astrocytic neoplasms.", HUMAN CELL : OFFICIAL JOURNAL OF HUMAN CELL RESEARCH SOCIETY MAR 2002, vol. 15, no. 1, March 2002 (2002-03-01), pages 25 - 31, XP009129228, ISSN: 0914-7470 *
See also references of WO2007114496A1 *

Also Published As

Publication number	Publication date
TW200808962A (en)	2008-02-16
KR20090026258A (ko)	2009-03-12
WO2007114496A1 (ja)	2007-10-11
JPWO2007114496A1 (ja)	2009-08-20
EP2527437A1 (de)	2012-11-28
EP2011869B1 (de)	2014-06-11
AU2007232706B2 (en)	2014-01-09
US20150307621A1 (en)	2015-10-29
JP2009189376A (ja)	2009-08-27
CN102659947B (zh)	2015-10-21
CN102659947A (zh)	2012-09-12
US8486402B2 (en)	2013-07-16
KR101370164B1 (ko)	2014-03-24
AU2007232706A1 (en)	2007-10-11
CA2648618A1 (en)	2007-10-11
CN101460623B (zh)	2012-06-27
US20100143367A1 (en)	2010-06-10
US9051374B2 (en)	2015-06-09
CA2648618C (en)	2016-06-21
EP2011869A1 (de)	2009-01-07
CN101460623A (zh)	2009-06-17
JP4324637B2 (ja)	2009-09-02
US20140037636A1 (en)	2014-02-06
PL2011869T3 (pl)	2014-11-28
ES2489641T3 (es)	2014-09-02
TWI390034B (zh)	2013-03-21
JP5160501B2 (ja)	2013-03-13
PT2011869E (pt)	2014-07-09
US20110280884A1 (en)	2011-11-17
US7943745B2 (en)	2011-05-17
US9688770B2 (en)	2017-06-27

Legal Events

Date	Code	Title	Description
2008-12-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2009-01-07	17P	Request for examination filed	Effective date: 20081028
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2009-01-07	AX	Request for extension of the european patent	Extension state: AL BA HR MK RS
2010-03-17	A4	Supplementary search report drawn up and despatched	Effective date: 20100217
2010-07-14	17Q	First examination report despatched	Effective date: 20100611
2010-08-04	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: KIRIN PHARMA KABUSHIKI KAISHA
2010-08-25	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: KYOWA HAKKO KIRIN CO., LTD.
2012-07-18	DAX	Request for extension of the european patent (deleted)
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