EP2043733A1 - Procédés et dispositifs d'administration de lofentanil et de carfentanil par électrotransport transdermique - Google Patents

Procédés et dispositifs d'administration de lofentanil et de carfentanil par électrotransport transdermique

Info

Publication number
EP2043733A1
EP2043733A1 EP07812362A EP07812362A EP2043733A1 EP 2043733 A1 EP2043733 A1 EP 2043733A1 EP 07812362 A EP07812362 A EP 07812362A EP 07812362 A EP07812362 A EP 07812362A EP 2043733 A1 EP2043733 A1 EP 2043733A1
Authority
EP
European Patent Office
Prior art keywords
lofentanil
carfentanil
electrotransport
delivery
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07812362A
Other languages
German (de)
English (en)
Inventor
Robert Martin Gale
Rama Padmanabhan
Joseph B. Phipps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/768,569 external-priority patent/US20080009782A1/en
Application filed by Alza Corp filed Critical Alza Corp
Publication of EP2043733A1 publication Critical patent/EP2043733A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444—Membrane

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)

Abstract

La présente invention concerne des procédés, systèmes et dispositifs d'administration de médicaments par transport électrique pour l'administration de lofentanil ou de carfentanil. Le lofentanil ou le carfentanil peuvent être fournis sous forme de sel soluble dans l'eau (par exemple, le chlorhydrate de lofentanil ou de carfentanil), tel que dans une formulation d'hydrogel. L'invention concerne également une dose de lofentanil ou de carfentanil administrée par transport électrique transdermique, qui est suffisante pour induire une analgésie chez des patients humains (adultes, par exemple) souffrant d'une douleur chronique, aiguë et/ou instable.
EP07812362A 2007-06-26 2007-06-27 Procédés et dispositifs d'administration de lofentanil et de carfentanil par électrotransport transdermique Withdrawn EP2043733A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/768,569 US20080009782A1 (en) 2006-06-28 2007-06-26 Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
PCT/US2007/072208 WO2009002337A1 (fr) 2006-06-28 2007-06-27 Procédés et dispositifs d'administration de lofentanil et de carfentanil par électrotransport transdermique

Publications (1)

Publication Number Publication Date
EP2043733A1 true EP2043733A1 (fr) 2009-04-08

Family

ID=39030862

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07812362A Withdrawn EP2043733A1 (fr) 2007-06-26 2007-06-27 Procédés et dispositifs d'administration de lofentanil et de carfentanil par électrotransport transdermique

Country Status (4)

Country Link
EP (1) EP2043733A1 (fr)
JP (1) JP2010531202A (fr)
CA (1) CA2656086A1 (fr)
WO (1) WO2009002337A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7422810B2 (ja) 2022-05-30 2024-01-26 キッコーマン株式会社 経皮通電パッチ
WO2025205761A1 (fr) * 2024-03-27 2025-10-02 株式会社カネカ Dispositif d'administration de médicament et procédé de production d'un dispositif d'administration de médicament

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141359A (en) 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US5224928A (en) 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
US5006108A (en) 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US5320597A (en) 1991-02-08 1994-06-14 Becton, Dickinson And Company Device and method for renewing electrodes during iontophoresis
US5047007A (en) 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5224927A (en) 1990-11-01 1993-07-06 Robert Tapper Iontophoretic treatment system
US5254081A (en) 1991-02-01 1993-10-19 Empi, Inc. Multiple site drug iontophoresis electronic device and method
US5246418A (en) 1991-12-17 1993-09-21 Becton Dickinson And Company Iontophresis system having features for reducing skin irritation
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5985316A (en) * 1995-04-28 1999-11-16 Alza Corporation Composition and method of enhancing electrotransport agent delivery
US6881208B1 (en) * 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
US6295469B1 (en) * 1997-11-14 2001-09-25 Alza Corporation Formulation for electrically assisted delivery of lidocaine and epinephrine
WO1999030773A1 (fr) * 1997-12-16 1999-06-24 Alza Corporation Regulateur avec charge artificielle permettant de maintenir un apport regule

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2009002337A1 *

Also Published As

Publication number Publication date
WO2009002337A1 (fr) 2008-12-31
CA2656086A1 (fr) 2008-12-31
JP2010531202A (ja) 2010-09-24

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