EP2049105A2 - Antimikrobielle photodynamische therapie - Google Patents
Antimikrobielle photodynamische therapieInfo
- Publication number
- EP2049105A2 EP2049105A2 EP07797049A EP07797049A EP2049105A2 EP 2049105 A2 EP2049105 A2 EP 2049105A2 EP 07797049 A EP07797049 A EP 07797049A EP 07797049 A EP07797049 A EP 07797049A EP 2049105 A2 EP2049105 A2 EP 2049105A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- gram
- microorganisms
- conjugate
- spacer
- photosensitizer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83383606P | 2006-07-27 | 2006-07-27 | |
| US11/880,974 US20090030257A1 (en) | 2007-07-25 | 2007-07-25 | Anti-microbial photodynamic therapy |
| PCT/US2007/016951 WO2009014524A2 (en) | 2006-07-27 | 2007-07-27 | Anti-microbial photodynamic therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2049105A2 true EP2049105A2 (de) | 2009-04-22 |
| EP2049105A4 EP2049105A4 (de) | 2022-03-30 |
Family
ID=40282008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP07797049.9A Withdrawn EP2049105A4 (de) | 2006-07-27 | 2007-07-27 | Antimikrobielle photodynamische therapie |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2049105A4 (de) |
| BR (1) | BRPI0714667A8 (de) |
| MX (1) | MX2009001074A (de) |
| WO (1) | WO2009014524A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220061106A (ko) | 2019-08-02 | 2022-05-12 | 코이트 헬스 오와이 | 전신적으로 적용하는 항생제의 항균 작용을 강화하는 방법 |
| CN114053406B (zh) * | 2021-11-23 | 2022-12-09 | 华中科技大学 | 一种多功能光热纳米杀菌材料及制备与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6462070B1 (en) * | 1997-03-06 | 2002-10-08 | The General Hospital Corporation | Photosensitizer conjugates for pathogen targeting |
| US20030215421A1 (en) * | 1999-07-21 | 2003-11-20 | Mcdonald John R. | Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders |
| EP1610751A4 (de) * | 2001-04-26 | 2006-05-24 | Univ Texas | Therapeutisches mittel/ligand-konjugat-zusammensetzungen, ihre syntheseverfahren und ihre anwendung |
| US20030176326A1 (en) * | 2002-03-15 | 2003-09-18 | Ceramoptec Industries Inc. | Photosensitzers for photodynamic therapy of microbial infections |
| US20040186087A1 (en) * | 2003-03-20 | 2004-09-23 | Ceramoptec Industries, Inc. | Siderophore conjugates of photoactive dyes for photodynamic therapy |
| AU2005204428A1 (en) * | 2004-01-07 | 2005-07-28 | Ambit Biosciences Corporation | Conjugated small molecules |
| US8153111B2 (en) * | 2004-06-18 | 2012-04-10 | Ceramoptec Industries, Inc. | Photo-triggered release of active substances from dendrimer-photosensitizer complexes |
-
2007
- 2007-07-27 EP EP07797049.9A patent/EP2049105A4/de not_active Withdrawn
- 2007-07-27 WO PCT/US2007/016951 patent/WO2009014524A2/en not_active Ceased
- 2007-07-27 BR BRPI0714667A patent/BRPI0714667A8/pt not_active Application Discontinuation
- 2007-07-27 MX MX2009001074A patent/MX2009001074A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009014524A3 (en) | 2020-10-15 |
| BRPI0714667A2 (pt) | 2013-08-06 |
| BRPI0714667A8 (pt) | 2016-10-18 |
| WO2009014524A2 (en) | 2009-01-29 |
| EP2049105A4 (de) | 2022-03-30 |
| MX2009001074A (es) | 2009-06-05 |
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| US8404636B2 (en) | Targeted delivery of antimicrobial agents | |
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| US20040186087A1 (en) | Siderophore conjugates of photoactive dyes for photodynamic therapy | |
| US9216166B2 (en) | Anti-microbial photodynamic therapy | |
| Caruso et al. | Enhanced photoinduced antibacterial activity of a BODIPY photosensitizer in the presence of polyamidoamines | |
| Grimmeisen et al. | Increasing the Selectivity of Light‐Active Antimicrobial Agents–Or How To Get a Photosensitizer to the Desired Target | |
| Zheng et al. | Poly (l-ornithine)-grafted zinc phthalocyanines as dual-functional antimicrobial agents with intrinsic membrane damage and photothermal ablation capacity | |
| Turky et al. | Antibacterial and in vitro anticancer activities of the antimicrobial peptide NRC‐07 encapsulated in chitosan nanoparticles | |
| Scanone et al. | Magnetic Nanoplatforms for In Situ Modification of Macromolecules: Synthesis, Characterization, and Photoinactivating Power of Cationic Nanoiman–Porphyrin Conjugates | |
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| WO2013015774A1 (en) | Glyco-substituted dihydroxy-chlorins and b-functionalized chlorins for anti-microbial photodynamic therapy | |
| EP2049105A2 (de) | Antimikrobielle photodynamische therapie | |
| JP5049010B2 (ja) | 光増感(photosensitisation)の使用 | |
| Kumar et al. | Targeting bacterial biofilms using vancomycin and multivalent cell‐penetrating peptide labeled quantum dots |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
| DAX | Request for extension of the european patent (deleted) | ||
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: BIOLITEC PHARMA IP & INVESTMENT LTD. |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG |
|
| R17D | Deferred search report published (corrected) |
Effective date: 20201015 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20210415 |
|
| RBV | Designated contracting states (corrected) |
Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Free format text: PREVIOUS MAIN CLASS: A61K0031407000 Ipc: A61K0041000000 |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20220225 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 31/04 20060101ALI20220221BHEP Ipc: A61K 31/407 20060101ALI20220221BHEP Ipc: A61K 47/64 20170101ALI20220221BHEP Ipc: A61K 41/00 20060101AFI20220221BHEP |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20240201 |