EP2054391A4 - Ein einzelnes tautomer enthaltendes, kristallines moxonidin und verfahren zu dessen herstellung - Google Patents

Ein einzelnes tautomer enthaltendes, kristallines moxonidin und verfahren zu dessen herstellung

Info

Publication number: EP2054391A4
Authority: EP; European Patent Office
Prior art keywords: moxonidine; crystalline; preparation process; process therefor; single tautomer
Prior art date: 2006-08-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP06780412A

Other languages

English (en)

French (fr)

Other versions

EP2054391A1 (de

Inventor

Itai Adin

Carmen Iustain

Alexander Weisman

Oded Arad

Joseph Kaspi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wavelength Pharmaceuticals Ltd

Original Assignee

Chemagis Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-08-17

Filing date

2006-08-17

Publication date

2009-08-26

2006-08-17 Application filed by Chemagis Ltd filed Critical Chemagis Ltd

2009-05-06 Publication of EP2054391A1 publication Critical patent/EP2054391A1/de

2009-08-26 Publication of EP2054391A4 publication Critical patent/EP2054391A4/de

Status Withdrawn legal-status Critical Current

Links

WPNJAUFVNXKLIM-UHFFFAOYSA-N Moxonidine Chemical compound COC1=NC(C)=NC(Cl)=C1NC1=NCCN1 WPNJAUFVNXKLIM-UHFFFAOYSA-N 0.000 title 1
229960003938 moxonidine Drugs 0.000 title 1
238000002360 preparation method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP06780412A 2006-08-17 2006-08-17 Ein einzelnes tautomer enthaltendes, kristallines moxonidin und verfahren zu dessen herstellung Withdrawn EP2054391A4 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/IL2006/000958 WO2008020425A1 (en)	2006-08-17	2006-08-17	Crystalline moxonidine comprising single tautomer and preparation process therefor

Publications (2)

Publication Number	Publication Date
EP2054391A1 EP2054391A1 (de)	2009-05-06
EP2054391A4 true EP2054391A4 (de)	2009-08-26

Family

ID=39081995

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP06780412A Withdrawn EP2054391A4 (de)	2006-08-17	2006-08-17	Ein einzelnes tautomer enthaltendes, kristallines moxonidin und verfahren zu dessen herstellung

Country Status (2)

Country	Link
EP (1)	EP2054391A4 (de)
WO (1)	WO2008020425A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2829540A1 (de) *	2013-07-26	2015-01-28	Abbott Healthcare Products B.V.	Synthese von substituierten Aminopyridinen

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1873152A1 (de) *	2006-06-26	2008-01-02	Chemagis Ltd.	Reinigungsverfahren von Moxonidine
EP1894926A1 (de) *	2006-06-26	2008-03-05	Chemagis Ltd.	Polymorphe von Moxonidine und Verfahren zu deren Herstellung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4323570A (en) *	1978-11-15	1982-04-06	Beiersdorf Aktiengesellschaft	Substituted aminopyrimidines

2006
- 2006-08-17 EP EP06780412A patent/EP2054391A4/de not_active Withdrawn
- 2006-08-17 WO PCT/IL2006/000958 patent/WO2008020425A1/en not_active Ceased

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1873152A1 (de) *	2006-06-26	2008-01-02	Chemagis Ltd.	Reinigungsverfahren von Moxonidine
EP1894926A1 (de) *	2006-06-26	2008-03-05	Chemagis Ltd.	Polymorphe von Moxonidine und Verfahren zu deren Herstellung

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CZESKIS B A: "Synthesis of triple [14C]-labeled moxonidine", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, JOHN WILEY, CHICHESTER, GB, vol. 47, no. 10, 1 January 2004 (2004-01-01), pages 699 - 704, XP002394964, ISSN: 0362-4803 *
See also references of WO2008020425A1 *

Also Published As

Publication number	Publication date
EP2054391A1 (de)	2009-05-06
WO2008020425A1 (en)	2008-02-21

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Legal Events

Date	Code	Title	Description
2009-04-03	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2009-05-06	17P	Request for examination filed	Effective date: 20090219
2009-05-06	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
2009-05-06	AX	Request for extension of the european patent	Extension state: AL BA HR MK RS
2009-08-26	A4	Supplementary search report drawn up and despatched	Effective date: 20090727
2010-01-08	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN
2010-02-10	18W	Application withdrawn	Effective date: 20091222