EP2076281A4 - Compositions alkylglycosidiques stabilisatrices et leurs procédés - Google Patents

Compositions alkylglycosidiques stabilisatrices et leurs procédés

Info

Publication number
EP2076281A4
EP2076281A4 EP06785482A EP06785482A EP2076281A4 EP 2076281 A4 EP2076281 A4 EP 2076281A4 EP 06785482 A EP06785482 A EP 06785482A EP 06785482 A EP06785482 A EP 06785482A EP 2076281 A4 EP2076281 A4 EP 2076281A4
Authority
EP
European Patent Office
Prior art keywords
methods
stabilizing
alkylglycoside compositions
compositions
stabilizing alkylglycoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06785482A
Other languages
German (de)
English (en)
Other versions
EP2076281A1 (fr
Inventor
Edward T Maggio
Michael R Ruff
Candace B Pert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aegis Therapeutics LLC
Original Assignee
Aegis Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aegis Therapeutics LLC filed Critical Aegis Therapeutics LLC
Priority to EP12165052.7A priority Critical patent/EP2505189B1/fr
Priority to EP09162179A priority patent/EP2158898A1/fr
Priority to EP09161107A priority patent/EP2158920A1/fr
Publication of EP2076281A1 publication Critical patent/EP2076281A1/fr
Publication of EP2076281A4 publication Critical patent/EP2076281A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
EP06785482A 2006-06-23 2006-06-23 Compositions alkylglycosidiques stabilisatrices et leurs procédés Withdrawn EP2076281A4 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP12165052.7A EP2505189B1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédé correspondant
EP09162179A EP2158898A1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédé correspondant
EP09161107A EP2158920A1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédés correspondants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2006/024577 WO2007149096A1 (fr) 2006-06-23 2006-06-23 Compositions alkylglycosidiques stabilisatrices et leurs procédés

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP12165052.7A Division EP2505189B1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédé correspondant
EP09161107.9 Division-Into 2009-05-26

Publications (2)

Publication Number Publication Date
EP2076281A1 EP2076281A1 (fr) 2009-07-08
EP2076281A4 true EP2076281A4 (fr) 2010-03-03

Family

ID=38833712

Family Applications (4)

Application Number Title Priority Date Filing Date
EP09161107A Withdrawn EP2158920A1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédés correspondants
EP12165052.7A Active EP2505189B1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédé correspondant
EP09162179A Withdrawn EP2158898A1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédé correspondant
EP06785482A Withdrawn EP2076281A4 (fr) 2006-06-23 2006-06-23 Compositions alkylglycosidiques stabilisatrices et leurs procédés

Family Applications Before (3)

Application Number Title Priority Date Filing Date
EP09161107A Withdrawn EP2158920A1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédés correspondants
EP12165052.7A Active EP2505189B1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédé correspondant
EP09162179A Withdrawn EP2158898A1 (fr) 2006-06-23 2006-06-23 Stabilisation de compositions alkylglycosidiques et procédé correspondant

Country Status (3)

Country Link
EP (4) EP2158920A1 (fr)
CA (2) CA2714867A1 (fr)
WO (1) WO2007149096A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7598343B1 (en) 2008-07-27 2009-10-06 The Medicines Company Pharmaceutical formulations of bivalirudin and processes of making the same
US7582727B1 (en) 2008-07-27 2009-09-01 The Medicinces Company Pharmaceutical formulations of bivalirudin and processes of making the same
WO2011094632A1 (fr) * 2010-01-29 2011-08-04 The Uab Research Foundation Procédé pour l'administration d'insuline et composition pharmaceutique de celle-ci
WO2011139838A2 (fr) * 2010-04-28 2011-11-10 Zelos Therapeutics, Inc. Formulations intranasales
SG186783A1 (en) * 2010-06-24 2013-02-28 Genentech Inc Compositions and methods containing alkylgycosides for stabilizing protein- containing formulations
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
DK3518892T5 (da) * 2016-09-29 2024-09-02 Arecor Ltd Farmaceutisk formulering, der indeholder en insulinforbindelse
IL277721B2 (en) 2018-04-04 2024-03-01 Arecor Ltd Medical infusion pump system for the delivery of an insulin compound
CN115015533B (zh) * 2022-05-31 2024-06-25 江西英大生物技术有限公司 一种氧化低密度脂蛋白测定试剂盒
CN117599193A (zh) * 2023-11-24 2024-02-27 皓阳生物科技(上海)有限公司 包含抗原和表面活性剂的物质组合物及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3219656A (en) 1963-08-12 1965-11-23 Rohm & Haas Alkylpolyalkoxyalkyl glucosides and process of preparation therefor
US3839318A (en) 1970-09-27 1974-10-01 Rohm & Haas Process for preparation of alkyl glucosides and alkyl oligosaccharides
DK149776C (da) 1984-01-06 1987-04-21 Orion Yhtymae Oy Antibiotisk virksom erytromycinforbindelse og praeparat indeholdende forbindelsen
AT382381B (de) 1984-10-02 1987-02-25 Oesterr Zuckerfab Evidenz Verfahren zur herstellung neuer grenzfl|chenaktiver kohlenhydrat-derivate
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
US5252318A (en) 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5661130A (en) 1993-06-24 1997-08-26 The Uab Research Foundation Absorption enhancers for drug administration
WO2006025882A2 (fr) * 2004-08-25 2006-03-09 The Uab Research Foundation Substances ameliorant l'absorption destinees a l'administration de medicaments

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ROCCATANO DANILO ET AL: "Mechanism by which 2,2,2-trifluoroethanol/water mixtures stabilize secondary-structure formation in peptides: a molecular dynamics study.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 17 SEP 2002, vol. 99, no. 19, 17 September 2002 (2002-09-17), pages 12179 - 12184, XP002563234, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
EP2505189B1 (fr) 2018-08-08
EP2505189A1 (fr) 2012-10-03
EP2158920A1 (fr) 2010-03-03
WO2007149096A1 (fr) 2007-12-27
EP2158898A1 (fr) 2010-03-03
EP2076281A1 (fr) 2009-07-08
CA2714867A1 (fr) 2007-12-27
CA2743725A1 (fr) 2007-12-27

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Legal Events

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AX Request for extension of the european patent

Extension state: AL BA HR MK RS

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 38/28 20060101ALI20100120BHEP

Ipc: A61K 47/26 20060101ALI20100120BHEP

Ipc: A61K 38/29 20060101ALI20100120BHEP

Ipc: A61K 38/27 20060101ALI20100120BHEP

Ipc: A61K 38/21 20060101ALI20100120BHEP

Ipc: A61K 38/18 20060101ALI20100120BHEP

Ipc: A61K 38/08 20060101ALI20100120BHEP

Ipc: A61K 9/19 20060101AFI20100120BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20100129

17Q First examination report despatched

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