EP2115465A4 - Chirurgische anwendungen für bmp-bindene proteine - Google Patents

Chirurgische anwendungen für bmp-bindene proteine

Info

Publication number
EP2115465A4
EP2115465A4 EP07868028A EP07868028A EP2115465A4 EP 2115465 A4 EP2115465 A4 EP 2115465A4 EP 07868028 A EP07868028 A EP 07868028A EP 07868028 A EP07868028 A EP 07868028A EP 2115465 A4 EP2115465 A4 EP 2115465A4
Authority
EP
European Patent Office
Prior art keywords
bmp
binding protein
surgical applications
surgical
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP07868028A
Other languages
English (en)
French (fr)
Other versions
EP2115465A2 (de
Inventor
Samuel S Murray
Elsa J Murray
Keyvan Behnam
Jeffrey C Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Veterans Affairs
University of California Berkeley
University of California San Diego UCSD
Original Assignee
US Department of Veterans Affairs
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/985,745 external-priority patent/US8193312B2/en
Application filed by US Department of Veterans Affairs, University of California Berkeley, University of California San Diego UCSD filed Critical US Department of Veterans Affairs
Publication of EP2115465A2 publication Critical patent/EP2115465A2/de
Publication of EP2115465A4 publication Critical patent/EP2115465A4/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
EP07868028A 2006-12-22 2007-12-26 Chirurgische anwendungen für bmp-bindene proteine Ceased EP2115465A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87682106P 2006-12-22 2006-12-22
US11/985,745 US8193312B2 (en) 2004-01-28 2007-11-16 Bone morphogenic protein binding peptide
PCT/US2007/026315 WO2008079400A2 (en) 2006-12-22 2007-12-26 Surgical applications for bmp binding protein

Publications (2)

Publication Number Publication Date
EP2115465A2 EP2115465A2 (de) 2009-11-11
EP2115465A4 true EP2115465A4 (de) 2011-08-10

Family

ID=39563120

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07868028A Ceased EP2115465A4 (de) 2006-12-22 2007-12-26 Chirurgische anwendungen für bmp-bindene proteine

Country Status (5)

Country Link
EP (1) EP2115465A4 (de)
JP (1) JP5466017B2 (de)
AU (1) AU2007338627B2 (de)
CA (1) CA2673600A1 (de)
WO (1) WO2008079400A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8188219B2 (en) 2004-01-28 2012-05-29 The Regents Of The University Of California Bone morphogenic protein binding peptide
US8193312B2 (en) * 2004-01-28 2012-06-05 The Regents Of The University Of California Bone morphogenic protein binding peptide
US8415302B2 (en) 2004-01-28 2013-04-09 The Regents Of The University Of California Surgical applications for BMP binding protein
WO2006093545A1 (en) 2004-11-29 2006-09-08 The Regents Of The University Of California Activating extraction of demineralized bone matrix
EP2445512B1 (de) * 2009-06-23 2018-08-29 The Regents of The University of California Verbesserung der bmp-aufrechterhaltung
HK1256356A1 (zh) * 2015-08-25 2019-09-20 伊斯迪德股份公司 用於诱导组织形成的化合物及其用途
US20180305408A1 (en) * 2015-08-25 2018-10-25 Histide Ag Compounds for inducing tissue formation and uses thereof
US12268733B2 (en) 2018-08-10 2025-04-08 Alexion Pharmaceuticals, Inc. Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase
AU2021337652B2 (en) 2020-09-04 2025-01-30 Alexion Pharmaceuticals, Inc. Methods for treating bone mineralization disorders
BR112023016048A2 (pt) 2021-02-12 2023-11-14 Alexion Pharma Inc Polipeptídeos de fosfatase alcalina e métodos de uso dos mesmos
KR20240045216A (ko) * 2021-07-05 2024-04-05 위니베르시테이트 마스트리흐트 칼슘 결정 침착 질환의 치료 수단 및 방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0409472A1 (de) * 1989-07-19 1991-01-23 Chiron Corporation Morphogenetisches Knochenprotein
WO2005072403A2 (en) * 2004-01-28 2005-08-11 The Regents Of The University Of California Bone morphogenic protein binding peptide
WO2006093545A1 (en) * 2004-11-29 2006-09-08 The Regents Of The University Of California Activating extraction of demineralized bone matrix

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0409472A1 (de) * 1989-07-19 1991-01-23 Chiron Corporation Morphogenetisches Knochenprotein
WO2005072403A2 (en) * 2004-01-28 2005-08-11 The Regents Of The University Of California Bone morphogenic protein binding peptide
WO2006093545A1 (en) * 2004-11-29 2006-09-08 The Regents Of The University Of California Activating extraction of demineralized bone matrix

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BEHNAM K ET AL: "BMP binding peptide: a BMP-2 enhancing factor deduced from the sequence of native bovine bone morphogenetic protein/non-collagenous protein", JOURNAL OF ORTHOPAEDIC RESEARCH, JOHN WILEY & SONS, INC, NEEDHAM, MA, vol. 23, no. 1, 1 January 2005 (2005-01-01), pages 175 - 180, XP004686456, ISSN: 0736-0266, DOI: 10.1016/J.ORTHRES.2004.05.001 *
HU B ET AL: "ISOLATION AND MOLECULAR CLONING OF A NOVEL BONE PHOSPHOPROTEIN RELATED IN SEQUENCE TO THE CYSTATIN FAMILY OF THIOL PROTEASE INHIBITORS", JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC., BALTIMORE, MD, US, vol. 270, no. 1, 1 January 1995 (1995-01-01), pages 431 - 436, XP000872932, ISSN: 0021-9258, DOI: 10.1074/JBC.270.1.431 *

Also Published As

Publication number Publication date
CA2673600A1 (en) 2008-07-03
JP2010513535A (ja) 2010-04-30
EP2115465A2 (de) 2009-11-11
AU2007338627B2 (en) 2013-08-15
AU2007338627A2 (en) 2010-01-28
AU2007338627A1 (en) 2008-07-03
JP5466017B2 (ja) 2014-04-09
WO2008079400A3 (en) 2008-08-21
WO2008079400A2 (en) 2008-07-03

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: WANG, JEFFREY C.

Inventor name: BEHNAM, KEYVAN

Inventor name: MURRAY, SAMUEL S.

Inventor name: MURRAY, ELSA J.

DAX Request for extension of the european patent (deleted)
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Effective date: 20110712

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