EP2139507A4 - METHODS AND COMPOSITIONS FOR STIMULATING AND PRESERVING BONE GROWTH - Google Patents

METHODS AND COMPOSITIONS FOR STIMULATING AND PRESERVING BONE GROWTH

Info

Publication number
EP2139507A4
EP2139507A4 EP07776368A EP07776368A EP2139507A4 EP 2139507 A4 EP2139507 A4 EP 2139507A4 EP 07776368 A EP07776368 A EP 07776368A EP 07776368 A EP07776368 A EP 07776368A EP 2139507 A4 EP2139507 A4 EP 2139507A4
Authority
EP
European Patent Office
Prior art keywords
stimulating
compositions
methods
bone growth
preserving bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07776368A
Other languages
German (de)
French (fr)
Other versions
EP2139507A1 (en
Inventor
Agnes Vignery
Nozer M Mehta
James P Gilligan
Kieran P Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Unigene Laboratories Inc
Original Assignee
Yale University
Unigene Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University, Unigene Laboratories Inc filed Critical Yale University
Publication of EP2139507A1 publication Critical patent/EP2139507A1/en
Publication of EP2139507A4 publication Critical patent/EP2139507A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Surgical Instruments (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP07776368A 2007-04-27 2007-04-27 METHODS AND COMPOSITIONS FOR STIMULATING AND PRESERVING BONE GROWTH Withdrawn EP2139507A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/010267 WO2008133618A1 (en) 2007-04-27 2007-04-27 Methods and compositions for fostering and preserving bone growth

Publications (2)

Publication Number Publication Date
EP2139507A1 EP2139507A1 (en) 2010-01-06
EP2139507A4 true EP2139507A4 (en) 2012-06-06

Family

ID=39925939

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07776368A Withdrawn EP2139507A4 (en) 2007-04-27 2007-04-27 METHODS AND COMPOSITIONS FOR STIMULATING AND PRESERVING BONE GROWTH

Country Status (6)

Country Link
EP (1) EP2139507A4 (en)
JP (1) JP2010526064A (en)
CN (1) CN101663043B (en)
AU (1) AU2007352435B2 (en)
CA (1) CA2685407A1 (en)
WO (1) WO2008133618A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3345607T1 (en) 2006-12-29 2023-03-31 Ossifi-Mab Llc Methods of altering bone growth by administration of sost or wise antagonist or agonist
CN101966348B (en) * 2010-09-21 2014-03-26 中国科学院深圳先进技术研究院 Strontium-doped hydroxyapatite and collagen composite material and application and preparation method thereof
TWI573558B (en) * 2015-09-30 2017-03-11 愛派司生技股份有限公司 Bone plate set having screws with a plurality of threaded areas
CN117502351A (en) * 2023-11-17 2024-02-06 西藏自治区农牧科学院水产科学研究所 A method for batch marking of Lhasa Schizothorax fingerlings

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002080933A1 (en) * 2001-04-03 2002-10-17 The Royal Alexandra Hospital For Children A drug for use in bone grafting
WO2004078223A1 (en) * 2003-03-05 2004-09-16 Bone Support Ab A new bone substitute composition
US20060089723A1 (en) * 2004-10-25 2006-04-27 Murphy Kieran P Method for bone augmentation
WO2006124708A1 (en) * 2005-05-19 2006-11-23 Unigene Laboratories, Inc. Bone implant device and methods of using same
WO2007038009A2 (en) * 2005-09-26 2007-04-05 Depuy Spine, Inc. Tissue augmentation, stabilization and regeneration technique

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8724897D0 (en) * 1987-10-23 1987-11-25 Downes S Material
ES2262642T3 (en) * 2000-04-05 2006-12-01 Kyphon Inc. DEVICE FOR THE TREATMENT OF FRACTURED AND / OR SICK BONES.
JP2004511320A (en) * 2000-10-16 2004-04-15 ユニバーシテイ・オブ・サウス・カロライナ Biocompatible cement containing reactive calcium phosphate nanoparticles and methods of making and using said cement
CN1294885C (en) * 2001-06-05 2007-01-17 江苏阳生生物工程有限公司 Biotechnological body bone tissue rack and its making process and use
TWI267378B (en) * 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
AU2002327007B2 (en) * 2001-09-21 2005-10-20 Stryker Corporation Pore-forming agents for orthopedic cements
JP2005519067A (en) * 2002-01-17 2005-06-30 ザ ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム Stimulation of bone growth and cartilage formation using thrombin peptide derivatives
US9532994B2 (en) * 2003-08-29 2017-01-03 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
US7531518B2 (en) * 2004-05-14 2009-05-12 Unigene Laboratories Inc. Method for fostering bone formation and preservation
US7175858B2 (en) * 2004-07-26 2007-02-13 Skeletal Kinetics Llc Calcium phosphate cements and methods for using the same
WO2006072622A2 (en) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
JP2006263184A (en) * 2005-03-24 2006-10-05 Gc Corp Bone cement injection and filling method and leakage prevention bag for injecting and filling bone cement
CA2608016A1 (en) * 2005-05-11 2006-11-23 Unigene Laboratories, Inc. Improving bone formation and preservation by surgically inducing an increase in osteoblast activity coupled with the effect of administering pthrp or cgrp

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002080933A1 (en) * 2001-04-03 2002-10-17 The Royal Alexandra Hospital For Children A drug for use in bone grafting
WO2004078223A1 (en) * 2003-03-05 2004-09-16 Bone Support Ab A new bone substitute composition
US20060089723A1 (en) * 2004-10-25 2006-04-27 Murphy Kieran P Method for bone augmentation
WO2006124708A1 (en) * 2005-05-19 2006-11-23 Unigene Laboratories, Inc. Bone implant device and methods of using same
WO2007038009A2 (en) * 2005-09-26 2007-04-05 Depuy Spine, Inc. Tissue augmentation, stabilization and regeneration technique

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
See also references of WO2008133618A1 *
SKRIPITZ R ET AL: "Parathyroid hormone (1-34) increases attachment of PMMA cement to bone", JOURNAL OF ORTHOPAEDIC SCIENCE, SPRINGER VERLAG. TOKYO, JP, vol. 6, no. 6, 1 January 2001 (2001-01-01), pages 540 - 544, XP002533458, ISSN: 0949-2658, DOI: 10.1007/S007760100010 *
SKRIPITZ R ET AL: "Strong effect of PTH (1-34) on regenerating bone: A time sequence study in rats", ACTA ORTHOPAEDICA SCANDINAVICA, MUNKSGAARD, COPENHAGEN, DK, vol. 71, no. 6, 1 December 2000 (2000-12-01), pages 619 - 624, XP002319215, ISSN: 0001-6470, DOI: 10.1080/000164700317362271 *

Also Published As

Publication number Publication date
CN101663043B (en) 2014-03-12
EP2139507A1 (en) 2010-01-06
JP2010526064A (en) 2010-07-29
CA2685407A1 (en) 2008-11-06
AU2007352435B2 (en) 2012-01-19
CN101663043A (en) 2010-03-03
WO2008133618A1 (en) 2008-11-06
AU2007352435A1 (en) 2008-11-06

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Legal Events

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DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20120507

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 45/06 20060101ALI20120501BHEP

Ipc: A61K 38/29 20060101AFI20120501BHEP

Ipc: A61P 19/00 20060101ALI20120501BHEP

Ipc: A61K 38/17 20060101ALI20120501BHEP

Ipc: A61K 31/59 20060101ALI20120501BHEP

Ipc: A61K 38/23 20060101ALI20120501BHEP

Ipc: A61K 38/18 20060101ALI20120501BHEP

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Effective date: 20140213

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Effective date: 20140826