EP2170874A4 - Neue verbindungen und deren verwendung - Google Patents

Neue verbindungen und deren verwendung

Info

Publication number
EP2170874A4
EP2170874A4 EP08762934A EP08762934A EP2170874A4 EP 2170874 A4 EP2170874 A4 EP 2170874A4 EP 08762934 A EP08762934 A EP 08762934A EP 08762934 A EP08762934 A EP 08762934A EP 2170874 A4 EP2170874 A4 EP 2170874A4
Authority
EP
European Patent Office
Prior art keywords
novel compounds
novel
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08762934A
Other languages
English (en)
French (fr)
Other versions
EP2170874A2 (de
Inventor
Simi Pushpan
Uma Ramachandran
Mrinalkanti Kundu
Veenaa Anantharaman
Santhosh Subramanian
Radhakrishnan Viswanathan
Ravikumar Tadiparthi
Maneesh Paul-Sathyaseela
Shakti Singh Solanki
Kesavan Koppolu
Sathishkumar Devarajan
Martin Gnanamuthu
Thanga Mariappan
Narayanan Surendran
Sriram Rajagopal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchid Research Laboratories Ltd
Original Assignee
Orchid Research Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Research Laboratories Ltd filed Critical Orchid Research Laboratories Ltd
Publication of EP2170874A2 publication Critical patent/EP2170874A2/de
Publication of EP2170874A4 publication Critical patent/EP2170874A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EP08762934A 2007-06-22 2008-06-20 Neue verbindungen und deren verwendung Withdrawn EP2170874A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1294CH2007 2007-06-22
IN560CH2008 2008-03-05
PCT/IB2008/001620 WO2009001192A2 (en) 2007-06-22 2008-06-20 Novel compounds and their use

Publications (2)

Publication Number Publication Date
EP2170874A2 EP2170874A2 (de) 2010-04-07
EP2170874A4 true EP2170874A4 (de) 2011-08-31

Family

ID=40186093

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08762934A Withdrawn EP2170874A4 (de) 2007-06-22 2008-06-20 Neue verbindungen und deren verwendung

Country Status (3)

Country Link
EP (1) EP2170874A4 (de)
CA (1) CA2692255A1 (de)
WO (1) WO2009001192A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102224151A (zh) 2008-11-20 2011-10-19 万能药生物有限公司 新的抗微生物剂
EP2766373B1 (de) * 2011-10-11 2016-08-17 Council of Scientific & Industrial Research Sila-analoga von oxazolidinon-derivaten und ihre herstellung
US10995097B2 (en) 2016-03-11 2021-05-04 The Board Of Trustees Of The University Of Illinois Small molecules active against gram-negative bacteria
US11274106B2 (en) 2017-06-23 2022-03-15 The Board Of Trustees Of The University Of Illinois Topoisomerase inhibitors with antibacterial and anticancer activity
CN115466253B (zh) * 2021-06-16 2024-08-20 沈阳药科大学 含二硫代氨基甲酸酯结构的噁唑烷酮类化合物及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998054161A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
WO2001044212A1 (en) * 1999-12-14 2001-06-21 Pharmacia & Upjohn Company Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent
US20010041728A1 (en) * 1997-05-30 2001-11-15 Hester Jackson B. Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US20020137754A1 (en) * 2000-02-10 2002-09-26 Hester Jackson B. Oxazolidinone thioamides with piperazine amide substituents
WO2004045616A1 (en) * 2002-11-21 2004-06-03 Pharmacia & Upjohn Company Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
US20050203102A1 (en) * 2004-03-09 2005-09-15 Orchid Chemicals & Pharmaceuticals Ltd. antibacterial agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000204084A (ja) * 1998-11-11 2000-07-25 Hokuriku Seiyaku Co Ltd チオカルバミド酸誘導体
WO2000032599A1 (en) * 1998-11-27 2000-06-08 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
ES2248284T3 (es) * 2000-02-10 2006-03-16 PHARMACIA & UPJOHN COMPANY LLC Oxazolidinontioamidas con sustituyentes piperazinamida.
CA2478502A1 (en) * 2002-04-01 2003-10-09 Cadila Healthcare Limited Novel antiinfective compounds, process for their preparation and pharmaceutical compositions containing them
WO2005113520A1 (en) * 2004-05-20 2005-12-01 Pharmacia & Upjohn Company Llc Substituted 2,3,5-trifluorphenyl oxazolidinones for use as antibacterial agents

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998054161A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US20010041728A1 (en) * 1997-05-30 2001-11-15 Hester Jackson B. Oxazolidinone antibacterial agents having a thiocarbonyl functionality
WO2001044212A1 (en) * 1999-12-14 2001-06-21 Pharmacia & Upjohn Company Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent
US20020137754A1 (en) * 2000-02-10 2002-09-26 Hester Jackson B. Oxazolidinone thioamides with piperazine amide substituents
WO2004045616A1 (en) * 2002-11-21 2004-06-03 Pharmacia & Upjohn Company Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
US20050203102A1 (en) * 2004-03-09 2005-09-15 Orchid Chemicals & Pharmaceuticals Ltd. antibacterial agents

Also Published As

Publication number Publication date
WO2009001192A3 (en) 2010-05-27
CA2692255A1 (en) 2008-12-31
EP2170874A2 (de) 2010-04-07
WO2009001192A2 (en) 2008-12-31

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA MK RS

R17D Deferred search report published (corrected)

Effective date: 20100527

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 31/04 20060101ALI20100601BHEP

Ipc: A61K 31/497 20060101ALI20100601BHEP

Ipc: A61K 31/422 20060101ALI20100601BHEP

Ipc: C07D 413/10 20060101AFI20100601BHEP

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Effective date: 20101126

RBV Designated contracting states (corrected)

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

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RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 31/04 20060101ALI20110728BHEP

Ipc: A61K 31/497 20060101ALI20110728BHEP

Ipc: A61K 31/422 20060101ALI20110728BHEP

Ipc: C07D 413/10 20060101AFI20110728BHEP

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