EP2196170A1 - Beutel und Beutelverbund für die Verpackung einer flüssigen biologischen Substanz, wie beispielsweise Tiersamen - Google Patents

Beutel und Beutelverbund für die Verpackung einer flüssigen biologischen Substanz, wie beispielsweise Tiersamen Download PDF

Info

Publication number: EP2196170A1
Authority: EP; European Patent Office
Prior art keywords: bag; needle; filling; opening; value
Prior art date: 2008-12-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP09178192A

Other languages

English (en)

French (fr)

Other versions

EP2196170B1 (de

Inventor

Pascal Lecointe

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

IMV Technologies SA

Original Assignee

IMV Technologies SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-12-15

Filing date

2009-12-07

Publication date

2010-06-16

2009-12-07 Application filed by IMV Technologies SA filed Critical IMV Technologies SA

2009-12-07 Priority to PL09178192T priority Critical patent/PL2196170T3/pl

2010-06-16 Publication of EP2196170A1 publication Critical patent/EP2196170A1/de

2016-07-27 Application granted granted Critical

2016-07-27 Publication of EP2196170B1 publication Critical patent/EP2196170B1/de

Status Active legal-status Critical Current

2029-12-07 Anticipated expiration legal-status Critical

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D19/00—Instruments or methods for reproduction or fertilisation
- A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
- A61D19/022—Containers for animal semen, e.g. pouches or vials ; Methods or apparatus for treating or handling animal semen containers, e.g. filling or closing

Definitions

the present invention relates to a packaging bag of a liquid biological substance, such as animal semen.
These bags are formed of two flexible plastic films joined and welded, usually by heat sealing, delimiting a substance receiving pocket.
the filling of the bags is done on a machine specially adapted for this purpose, in which the band of bags scrolls step by step.
the bags are suspended in a vertical position so that their filling opening is directed upwards.
the desired dose of substance is delivered by means of a hollow needle, via a flexible supply line, one end of which is connected to a container containing the substance and the other to the hollow needle; the duct is equipped with a peristaltic pump that ensures accurate dose distribution.
the band of bags is stopped, and the needle, which is also vertical, enters the opening of the bag to be filled and goes down inside the pocket, until approximately mid-height of it, or even lower; the dose of substance is injected into the bag by the lower end of the needle, then the needle is withdrawn by a vertical movement from bottom to top, after which the area of the opening is closed by thermo welding.
the substance is pushed out of the bag and brought to the insemination probe, either through the same opening, after opening the welded zone, or by means of a cannula disposed at the opposite end of the bag, for example according to the teachings of the document EP-B-1 317 224 .
the substance is composed of boar semen mixed with a diluent liquid containing preservatives such as sugars, citrates and albumin, which make the substance foaming.
foam at the time of filling is favored by the relatively high flow rate of the substance when it leaves the needle, a high flow rate being necessary so that the filling of the bags can be done at a suitable rate (generally 2 seconds approximately per sachet).
This foam has a tendency to adhere to the needle and accompany it during its withdrawal, in the area of the opening in which the welding must take place, or even outside this area.
a fraction of the seed is removed from the bag, which is not satisfactory for the accuracy of the assay.
the possible presence of seed outside the bag is a possible cause of unexpected transfer of spermatozoa from one bag to another within a lot of sachets filled and stored side by side; the liquid out of the bag may also alter the marking, by dilution of the ink, which may in particular pose difficulties for reading identification tags.
WO 94/22731 a packaging structure of a liquid material, which comprises sealing means arranged so that, even when the bag is full and not connected to a discharge pipe, there is no risk of loss of liquid through its discharge opening.
WO 02/32469 relates to a liquid packaging bag, and more specifically to a technique for inactivating pathogens in fluids such as blood.
the bag is filled by means of one or more openings, possibly pre-connected to tubing, and the procedure is followed. sealing of this opening so as to form a seal around said opening.
the present invention aims to solve the difficulties mentioned above, by preventing the foam formed from accompanying the injection needle during removal from the filling opening of the bag.
the invention therefore relates to a sachet for packaging a liquid biological substance, such as animal semen, consisting of two flexible plastic films contiguous and welded, delimiting a substance receiving pocket, which has one of the its ends an opening for filling the empty bag by means of a hollow cylindrical needle.
these films have a pair of mutual welding lines, which form tabs starting from said opening and penetrating axially and symmetrically into the internal space of the bag converging towards the inside thereof, their free ends being separated from each other. They are of a value "e” which is substantially equal to ⁇ d / 2, "d” being the value of the diameter of said needle, introduced into the bag, for filling.
the needle passes between the tabs for filling the bag, and the latter ensure the scraping of the needle during removal.
the two welded lines converge forming an apex angle whose value ⁇ is between 20 and 60 °, advantageously close to 45 °, which performs a particularly effective scraping and cleaning of the needle.
the invention also relates to a strip of bags formed of a juxtaposition of bags having the above characteristics, which are adjacent to each other and separated by a pre-cut line.
the bag 1 represented on the figure 1 is intended to contain boar semen for subsequent artificial insemination of a sow.
Each sachet has an elongated rectangular overall shape, the major axis of symmetry of which is designated X-X '. Its contour is delimited by two welded lateral edges 10, a first closed end zone 11 (bottom), also welded, and a second end zone comprising two welded zones 12a, 12b separated by an opening 4 for filling.
This plastics material is preferably transparent or translucent and consists for example of polyethylene, polyamide or polyethylene terephthalate (PET).
PET polyethylene terephthalate
the two films are preferably made of two separate sheets. However, one can make use of one and the same sheet that has been folded on itself.
Each sheet can be single or multilayer
the bag 1 is separated from the two adjacent bags 1A and 1B by precut lines 100A, respectively 100B, connecting end perforations 101-102, as is well known.
zones 12a and 12b are drilled openings 3, 3 'which serve to receive the driving fingers and retaining the bags, in the suspended position, in the filling machine.
one 3 'of these orifices has an oblong shape, being formed of two circular holes partially overlapping.
a dump cannula 2 In the bottom zone 11 is integrated a dump cannula 2, axis X-X ', integrated in the bag, for example in accordance with the teachings of the document EP-B-1 317 224 .
the longitudinal edges of the strip, outside the zones 12a-12b and the filling opening 4 are disjoint (not welded) and can therefore be spaced freely from one another.
the opening 4 has a main portion 6, which will be designated conventionally "mouth”, delimited by the edges vis-à-vis the welded portions 12a and 12b, which edges are parallel to the axis XX 'and spaced apart. a distance "a”. These edges extend inside the bag by weld lines 7 in the form of straight tabs. These are inclined symmetrically with respect to the median axis X-X 'so as to converge towards the inside of the bag, forming a cut-off "V".
This value "e” is adapted to the diameter "d" of the hollow needle used for filling, so that when the needle passes axially through the opening 6 it pushes the areas of plastic film around this narrowed passage, referenced 70 on the figure 1 , making him take a circular shape of corresponding diameter.
the value "e” is substantially equal to 1 ⁇ 2 ⁇ d.
the width "a" of the mouth zone 6 is significantly larger than the diameter "d" of the needle 8.
the needle 8 is withdrawn by an axial translation movement from bottom to top, symbolized by the arrow F on the figure 2 .
the reference M denotes foam adhering against the wall of the needle 8.
the ends of the tongues 7, such as flexible lips, as well as the edges of plastic film at the right of the narrowed passage 70 scrape this wall and retain the foam M, by deflecting laterally under the oblique welding lines 7, as symbolized by the arrows G.
the foam remains trapped inside the bag, without contaminating the mouth 6, according to the desired objective.
the filling opening is then closed tightly, under good conditions, by a heat-sealing line 9.
the tongues 7 each have a bulge-shaped end expansion 71.
the presence of the beads 71 reinforces the ends of the tongues by limiting the risk of initiation of rupture at this level when the bag is subjected to high mechanical stresses, including torsion, for emptying during insemination ( via the cannula 2).
Variant 5 illustrates another possible shutter mode of the bag after filling.
this passage opens with a 90 profile V-shaped area.
the filling opening 4 can also be used for emptying, which is particularly useful for closed-bottomed bags, as described for example in the document FR-A-2,667,504 .
the passage 91 acts as emptying duct and the portion 90 of centering cone for the introduction of the insemination probe.
a needle with a bevelled end is used with conventional bags to facilitate its introduction into the bag, but which presents a risk of the flow of a small quantity of substance retained in the needle, after it has been removed from the bag.

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Reproductive Health (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bag Frames (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)

EP09178192.2A 2008-12-15 2009-12-07 Beutel und Beutelverbund für die Verpackung einer flüssigen biologischen Substanz, wie beispielsweise Tiersamen Active EP2196170B1 (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
PL09178192T PL2196170T3 (pl)	2008-12-15	2009-12-07	Woreczek i taśma woreczków do kondycjonowania ciekłej substancji biologicznej, takiej jak nasienie zwierzęce

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0858587A FR2939774B1 (fr)	2008-12-15	2008-12-15	Sachet et bandes de sachet pour le conditionnement d'une substance biologique liquide, telle que de la semence animale.

Publications (2)

Publication Number	Publication Date
EP2196170A1 true EP2196170A1 (de)	2010-06-16
EP2196170B1 EP2196170B1 (de)	2016-07-27

Family

ID=40941844

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP09178192.2A Active EP2196170B1 (de)	2008-12-15	2009-12-07	Beutel und Beutelverbund für die Verpackung einer flüssigen biologischen Substanz, wie beispielsweise Tiersamen

Country Status (6)

Country	Link
US (1)	US20100150480A1 (de)
EP (1)	EP2196170B1 (de)
DK (1)	DK2196170T3 (de)
ES (1)	ES2597440T3 (de)
FR (1)	FR2939774B1 (de)
PL (1)	PL2196170T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9539158B2 (en)	2013-06-19	2017-01-10	American Innotek, Inc.	Liquid sequestration bag with pinch closure
FR3027794B1 (fr) *	2014-11-04	2016-12-30	Imv Tech	Sachet de conditionnement de semence animale diluee convenant pour l'insemination artificielle, en particulier des especes porcines ; et systeme le comportant
CN113288802B (zh) *	2021-05-07	2022-08-05	闫一娇	营养液供给装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994022731A1 (en) *	1993-03-29	1994-10-13	Plum Kemi Produktion A/S	A bag or pouch for containing a fluid
WO2002022044A1 (fr) *	2000-09-13	2002-03-21	Eurl Packins	Sachet de conditionnement de substance a canule integree et bande constituee de tels sachets
WO2002032469A2 (en) *	2000-10-17	2002-04-25	Gambro, Inc.	Container and method of sealing

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US2349962A (en) *	1942-02-12	1944-05-30	Griffiths Hughes Ltd E	Container
US2566632A (en) *	1949-08-15	1951-09-04	George J Propp	Artificial insemination device
US2804257A (en) *	1953-08-27	1957-08-27	Dreyer Andre	Impervious container for liquid or gaseous fluids
US3112047A (en) *	1960-11-01	1963-11-26	Cherry Burrell Corp	Liquid-tight container
US3263903A (en) *	1964-05-21	1966-08-02	Waller Lindquist Inc	Valved container
US3340671A (en) *	1964-08-10	1967-09-12	Carnation Co	Method of filling containers under aseptic conditions
US3424218A (en) *	1966-12-07	1969-01-28	Garrett Corp	Medical material container
FR2225351B1 (de) *	1973-04-10	1978-10-27	Thimonnier & Cie
US4265279A (en) *	1979-08-06	1981-05-05	Weikert Roy J	Package for maintaining asepsis of a sterile web of bags and method of using
US4641362A (en) *	1984-10-25	1987-02-03	C. Muller & Associates, Inc.	Protective dispensing assembly for ultrapure liquids
US4686814A (en) *	1985-06-03	1987-08-18	Yanase Waitch K.K.	Bag for containing flowable foodstuff
DK152644B (da) *	1986-04-22	1988-04-05	Lindknud Plast As	Foliepose med ventil
US5354132A (en) *	1987-01-14	1994-10-11	American Innotek, Inc.	Fluid containment bag
US4828187A (en) *	1987-07-06	1989-05-09	Aaxon Industrial, Inc.	Particulate separation chamber and bag disposal means in a negative pressure system for collection of hazardous material
FR2617864B1 (fr) *	1987-07-10	1990-08-17	Instr Medecine Veterinaire	Receptacle de confinement d'un liquide biologique
US4825915A (en) *	1987-11-17	1989-05-02	Bergen Hess	Funnel construction system
US4974732A (en) *	1990-02-02	1990-12-04	S. C. Johnson & Son, Inc.	Sealed pouch having tear-open spout
EP0574496B1 (de) *	1991-03-05	1994-09-28	Schur Consumer Products A/S	Gefrierformbeutel
US5391163A (en) *	1992-01-31	1995-02-21	Inpaco Corporation	Pouch for administering medical fluids
FR2728456B1 (fr) *	1994-12-23	1997-03-21	Instr Medecine Veterinaire	Machine de fabrication de doses pretes a l'emploi, de semence animale, et dose de semence realisee par cette machine
US5655653A (en) *	1995-07-11	1997-08-12	Minnesota Mining And Manufacturing Company	Pouch for orthodontic appliance
US6050935A (en) *	1997-05-09	2000-04-18	Biofertec	Container assembly for intravaginal fertilization and culture and embryo transfer and method of intravaginal fertilization and culture employing such a container
US6149579A (en) *	1998-03-23	2000-11-21	Lee; Won Ku	Semen storage container and its stopper
US6551819B1 (en) *	2000-06-29	2003-04-22	Minitube Of America, Inc.	Container for semen and other biological liquids
FR2823435B1 (fr) *	2001-04-11	2004-06-11	Imv Technologies	Sachet de conditionnement de semence animale et de traitement uterin
US20040161177A1 (en) *	2003-02-14	2004-08-19	N'dia Franck-Phillippe	Easily opened fluid pouch
US8025855B2 (en) *	2008-07-25	2011-09-27	Continental Plastic Corp.	Semen container with specialized tip

2008
- 2008-12-15 FR FR0858587A patent/FR2939774B1/fr active Active
2009
- 2009-12-07 DK DK09178192.2T patent/DK2196170T3/en active
- 2009-12-07 PL PL09178192T patent/PL2196170T3/pl unknown
- 2009-12-07 ES ES09178192.2T patent/ES2597440T3/es active Active
- 2009-12-07 EP EP09178192.2A patent/EP2196170B1/de active Active
- 2009-12-15 US US12/653,551 patent/US20100150480A1/en not_active Abandoned

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994022731A1 (en) *	1993-03-29	1994-10-13	Plum Kemi Produktion A/S	A bag or pouch for containing a fluid
WO2002022044A1 (fr) *	2000-09-13	2002-03-21	Eurl Packins	Sachet de conditionnement de substance a canule integree et bande constituee de tels sachets
WO2002032469A2 (en) *	2000-10-17	2002-04-25	Gambro, Inc.	Container and method of sealing

Also Published As

Publication number	Publication date
ES2597440T3 (es)	2017-01-18
US20100150480A1 (en)	2010-06-17
DK2196170T3 (en)	2016-10-10
FR2939774A1 (fr)	2010-06-18
FR2939774B1 (fr)	2013-07-05
EP2196170B1 (de)	2016-07-27
PL2196170T3 (pl)	2017-05-31

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