EP2214010A3 - Passeur automatique d'échantillons à haut débit - Google Patents

Passeur automatique d'échantillons à haut débit Download PDF

Info

Publication number
EP2214010A3
EP2214010A3 EP10160627A EP10160627A EP2214010A3 EP 2214010 A3 EP2214010 A3 EP 2214010A3 EP 10160627 A EP10160627 A EP 10160627A EP 10160627 A EP10160627 A EP 10160627A EP 2214010 A3 EP2214010 A3 EP 2214010A3
Authority
EP
European Patent Office
Prior art keywords
insoluble matrix
fluid over
high throughput
analyte
eluting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10160627A
Other languages
German (de)
English (en)
Other versions
EP2214010A2 (fr
EP2214010B1 (fr
Inventor
Can Ozbal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocius Life Sciences Inc
Original Assignee
Biocius Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocius Life Sciences Inc filed Critical Biocius Life Sciences Inc
Publication of EP2214010A2 publication Critical patent/EP2214010A2/fr
Publication of EP2214010A3 publication Critical patent/EP2214010A3/fr
Application granted granted Critical
Publication of EP2214010B1 publication Critical patent/EP2214010B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/40—Flow patterns using back flushing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/324—Control of physical parameters of the fluid carrier of pressure or speed speed, flow rate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/40—Flow patterns using back flushing
    • G01N2030/405—Flow patterns using back flushing re-concentrating or inverting previous separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N2030/626—Detectors specially adapted therefor calibration, baseline
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves

Landscapes

  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Threshing Machine Elements (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
EP10160627.5A 2003-11-07 2004-11-08 Passeur automatique d'échantillons à haut débit Expired - Lifetime EP2214010B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51824003P 2003-11-07 2003-11-07
EP04800778A EP1685397B1 (fr) 2003-11-07 2004-11-08 Passeur automatique d'echantillons a haut debit

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP04800778.5 Division 2004-11-08
EP04800778A Division EP1685397B1 (fr) 2003-11-07 2004-11-08 Passeur automatique d'echantillons a haut debit

Publications (3)

Publication Number Publication Date
EP2214010A2 EP2214010A2 (fr) 2010-08-04
EP2214010A3 true EP2214010A3 (fr) 2011-03-30
EP2214010B1 EP2214010B1 (fr) 2017-07-19

Family

ID=34590239

Family Applications (2)

Application Number Title Priority Date Filing Date
EP10160627.5A Expired - Lifetime EP2214010B1 (fr) 2003-11-07 2004-11-08 Passeur automatique d'échantillons à haut débit
EP04800778A Expired - Lifetime EP1685397B1 (fr) 2003-11-07 2004-11-08 Passeur automatique d'echantillons a haut debit

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP04800778A Expired - Lifetime EP1685397B1 (fr) 2003-11-07 2004-11-08 Passeur automatique d'echantillons a haut debit

Country Status (6)

Country Link
EP (2) EP2214010B1 (fr)
JP (1) JP4613279B2 (fr)
AT (1) ATE494547T1 (fr)
CA (1) CA2548073A1 (fr)
DE (1) DE602004030938D1 (fr)
WO (1) WO2005048126A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8414774B2 (en) 2001-04-25 2013-04-09 Agilent Technologies, Inc. Systems and methods for high-throughput screening of fluidic samples
EP2217903B1 (fr) * 2007-11-02 2019-04-03 Biocius Life Sciences, Inc. Système d'injection d'échantillons
WO2009111228A2 (fr) * 2008-02-29 2009-09-11 Waters Technologies Corporation Surveillance chromatographique et commande de plusieurs flux de traitement
CN102171560B (zh) * 2008-10-03 2014-06-04 爱科来株式会社 分析装置及其控制方法
GB0917735D0 (en) 2009-10-09 2009-11-25 Sphere Medical Ltd Sensor
GB201017256D0 (en) 2010-10-13 2010-11-24 Sphere Medical Ltd Sensor and method
GB201017479D0 (en) * 2010-10-15 2010-12-01 Sphere Medical Ltd Analyte Extraction apparatus and method
EP3017291A4 (fr) * 2013-07-03 2017-01-25 Wyatt Technology Corporation Procédé et appareil pour contrôler un report d'échantillon dans des instruments d'analyse
US10585075B2 (en) 2014-02-27 2020-03-10 Elemental Scientific, Inc. System for collecting liquid samples
KR102445624B1 (ko) * 2014-02-27 2022-09-21 엘리멘탈 사이언티픽, 인코포레이티드 원거리에서 액체 샘플을 수집하기 위한 시스템
KR102608219B1 (ko) 2015-06-26 2023-11-29 엘리멘탈 사이언티픽, 인코포레이티드 액체 샘플 수집을 위한 시스템
JP6577132B2 (ja) 2016-03-07 2019-09-25 株式会社日立ハイテクノロジーズ 分析装置
DE102016121515A1 (de) * 2016-11-10 2018-05-17 Dionex Softron Gmbh Verfahren zum Einführen einer Probe in eine Trennsäule und entsprechendes System
US11298701B2 (en) 2018-11-26 2022-04-12 King Instrumentation Technologies Microtiter plate mixing control system
EP3896443B1 (fr) 2020-04-15 2024-05-01 F. Hoffmann-La Roche AG Système analytique et procédé comprenant une commutation entre des flux de chromatographie liquide
WO2021241357A1 (fr) * 2020-05-29 2021-12-02 株式会社日立ハイテク Procédé de commande pour dispositif d'analyse automatique
CN113075339A (zh) * 2021-04-28 2021-07-06 大庆东鼎仪器制造有限公司 轻烃减压等组成转化装置及方法
CN116973517B (zh) * 2023-08-08 2024-03-26 中国科学院大气物理研究所 一种大气痕量气体排放与沉降通量测量装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3524305A (en) * 1967-12-26 1970-08-18 Phillips Petroleum Co Minimizing switching transients in multiple column chromatography
US4913821A (en) * 1989-04-27 1990-04-03 The Dow Chemical Company Method for the determination of phenols in water
US5814742A (en) * 1996-10-11 1998-09-29 L C Packings, Nederland B.V. Fully automated micro-autosampler for micro, capillary and nano high performance liquid chromatography

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3192401B2 (ja) * 1997-04-01 2001-07-30 和光純薬工業株式会社 液体試料成分の分離方法及び該方法に使用する装置
TW422712B (en) * 1997-04-01 2001-02-21 Wako Pure Chem Ind Ltd Liquid test components separation method and equipment thereof
JP2000123784A (ja) * 1998-10-15 2000-04-28 Hitachi Ltd 四重極質量分析装置

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3524305A (en) * 1967-12-26 1970-08-18 Phillips Petroleum Co Minimizing switching transients in multiple column chromatography
US4913821A (en) * 1989-04-27 1990-04-03 The Dow Chemical Company Method for the determination of phenols in water
US5814742A (en) * 1996-10-11 1998-09-29 L C Packings, Nederland B.V. Fully automated micro-autosampler for micro, capillary and nano high performance liquid chromatography

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J.A. PASCUAL,G.J. TEN HOVE,A.P.J.M. DE JONG: "Development of a Precolumn Capillary Liquid Chromatography Switching System for Coupling to Mass Spectrometry", JOURNAL OF MICROCOLUMN SEPARATIONS, vol. 8, no. 6, 1996, pages 383 - 387, XP002622657, ISSN: 1520-667X, DOI: 10.1002/(SICI)1520-667X(1996)8:6<383::AID-MCS2>3.0.CO;2-Y *

Also Published As

Publication number Publication date
EP1685397A2 (fr) 2006-08-02
WO2005048126A3 (fr) 2005-12-22
EP2214010A2 (fr) 2010-08-04
WO2005048126A2 (fr) 2005-05-26
JP4613279B2 (ja) 2011-01-12
EP2214010B1 (fr) 2017-07-19
EP1685397B1 (fr) 2011-01-05
JP2007512515A (ja) 2007-05-17
CA2548073A1 (fr) 2005-05-26
ATE494547T1 (de) 2011-01-15
DE602004030938D1 (de) 2011-02-17

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