EP2224915A4 - Compositions pharmaceutiques - Google Patents

Compositions pharmaceutiques

Info

Publication number
EP2224915A4
EP2224915A4 EP08866252.3A EP08866252A EP2224915A4 EP 2224915 A4 EP2224915 A4 EP 2224915A4 EP 08866252 A EP08866252 A EP 08866252A EP 2224915 A4 EP2224915 A4 EP 2224915A4
Authority
EP
European Patent Office
Prior art keywords
pharmaceutical composition
pharmaceutical
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08866252.3A
Other languages
German (de)
English (en)
Other versions
EP2224915A1 (fr
Inventor
Alfred Liang
Frank Matthews
Garth Boehm
Lijuan Tang
Frank Johnson
Joseph Stauffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpharma Pharmaceuticals LLC
Original Assignee
Alpharma Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpharma Pharmaceuticals LLC filed Critical Alpharma Pharmaceuticals LLC
Publication of EP2224915A1 publication Critical patent/EP2224915A1/fr
Publication of EP2224915A4 publication Critical patent/EP2224915A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP08866252.3A 2007-12-17 2008-12-16 Compositions pharmaceutiques Withdrawn EP2224915A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US793507P 2007-12-17 2007-12-17
PCT/US2008/087043 WO2009085778A1 (fr) 2007-12-17 2008-12-16 Compositions pharmaceutiques

Publications (2)

Publication Number Publication Date
EP2224915A1 EP2224915A1 (fr) 2010-09-08
EP2224915A4 true EP2224915A4 (fr) 2014-01-22

Family

ID=40824650

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08866252.3A Withdrawn EP2224915A4 (fr) 2007-12-17 2008-12-16 Compositions pharmaceutiques

Country Status (4)

Country Link
EP (1) EP2224915A4 (fr)
AU (1) AU2008343267A1 (fr)
CA (1) CA2709950A1 (fr)
WO (1) WO2009085778A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU776666B2 (en) 2000-02-08 2004-09-16 Euro-Celtique S.A. Tamper-resistant oral opioid agonist formulations
WO2003013525A1 (fr) 2001-08-06 2003-02-20 Euro-Celtique S.A. Formulations d'agoniste opioide a antagoniste liberable et sequestre
US20030157168A1 (en) 2001-08-06 2003-08-21 Christopher Breder Sequestered antagonist formulations
US7332182B2 (en) 2001-08-06 2008-02-19 Purdue Pharma L.P. Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant
US7157103B2 (en) 2001-08-06 2007-01-02 Euro-Celtique S.A. Pharmaceutical formulation containing irritant
US7842307B2 (en) 2001-08-06 2010-11-30 Purdue Pharma L.P. Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent
TWI347201B (en) 2003-04-21 2011-08-21 Euro Celtique Sa Pharmaceutical products,uses thereof and methods for preparing the same
WO2009079518A1 (fr) * 2007-12-17 2009-06-25 Alpharma Pharmaceuticals. Llc Composition pharmaceutique
AU2008346870A1 (en) * 2007-12-17 2009-07-16 Alpharma Pharmaceuticals, Llc Pharmaceutical composition
JP2012087101A (ja) * 2010-10-21 2012-05-10 Holger Hermann Lars オピオイドおよびオピオイド拮抗薬を含む微粒子医薬組成物
US9456986B2 (en) 2013-12-11 2016-10-04 Develco Pharma Schweiz Ag Naloxone mono preparation and multilayer tablet
US10105360B2 (en) 2013-12-11 2018-10-23 Develco Pharma Schweiz Ag Method and composition for the treatment of opioid induced constipation

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033566A2 (fr) * 1996-03-12 1997-09-18 Alza Corporation Composition et forme galenique contenant un antagoniste des opioides
WO2001058451A1 (fr) * 2000-02-08 2001-08-16 Euro-Celtique, S.A. Formes orales inviolables d'agonistes de l'opioide
WO2004026283A1 (fr) * 2002-09-20 2004-04-01 Alpharma, Inc. Sous-unite de sequestration et compositions et procedes associes
US20040202717A1 (en) * 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
US20050191244A1 (en) * 2002-10-25 2005-09-01 Gruenenthal Gmbh Abuse-resistant pharmaceutical dosage form
WO2007149438A2 (fr) * 2006-06-19 2007-12-27 Alpharma, Inc. Compositions pharmaceutiques
WO2008027442A2 (fr) * 2006-08-30 2008-03-06 Theraquest Biosciences, Llc Formulations pharmaceutiques orales anti-abus à base d'opioïdes et procédé d'utilisation
WO2008063301A2 (fr) * 2006-10-11 2008-05-29 Alpharma, Inc. Compositions pharmaceutiques
WO2009032270A2 (fr) * 2007-09-04 2009-03-12 Alpharma, Inc. Compositions pharmaceutiques
WO2009079518A1 (fr) * 2007-12-17 2009-06-25 Alpharma Pharmaceuticals. Llc Composition pharmaceutique
WO2009088673A2 (fr) * 2007-12-17 2009-07-16 Alpharma Pharmaceuticals, Llc Composition pharmaceutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050106249A1 (en) * 2002-04-29 2005-05-19 Stephen Hwang Once-a-day, oral, controlled-release, oxycodone dosage forms
US20050245557A1 (en) * 2003-10-15 2005-11-03 Pain Therapeutics, Inc. Methods and materials useful for the treatment of arthritic conditions, inflammation associated with a chronic condition or chronic pain
US20070269505A1 (en) * 2003-12-09 2007-11-22 Flath Robert P Tamper Resistant Co-Extruded Dosage Form Containing An Active Agent And An Adverse Agent And Process Of Making Same

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033566A2 (fr) * 1996-03-12 1997-09-18 Alza Corporation Composition et forme galenique contenant un antagoniste des opioides
WO2001058451A1 (fr) * 2000-02-08 2001-08-16 Euro-Celtique, S.A. Formes orales inviolables d'agonistes de l'opioide
WO2004026283A1 (fr) * 2002-09-20 2004-04-01 Alpharma, Inc. Sous-unite de sequestration et compositions et procedes associes
US20050191244A1 (en) * 2002-10-25 2005-09-01 Gruenenthal Gmbh Abuse-resistant pharmaceutical dosage form
US20040202717A1 (en) * 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
WO2007149438A2 (fr) * 2006-06-19 2007-12-27 Alpharma, Inc. Compositions pharmaceutiques
WO2008027442A2 (fr) * 2006-08-30 2008-03-06 Theraquest Biosciences, Llc Formulations pharmaceutiques orales anti-abus à base d'opioïdes et procédé d'utilisation
WO2008063301A2 (fr) * 2006-10-11 2008-05-29 Alpharma, Inc. Compositions pharmaceutiques
WO2009032270A2 (fr) * 2007-09-04 2009-03-12 Alpharma, Inc. Compositions pharmaceutiques
WO2009079518A1 (fr) * 2007-12-17 2009-06-25 Alpharma Pharmaceuticals. Llc Composition pharmaceutique
WO2009088673A2 (fr) * 2007-12-17 2009-07-16 Alpharma Pharmaceuticals, Llc Composition pharmaceutique

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOHNSON F ET AL: "(236) Relative bioavailability of plasma naltrexone from crushed ALO-01 (an investigational, abuse-deterrent, extended-release, morphine sulfate formulation with sequestered naltrexone) to a naltrexone oral solution", JOURNAL OF PAIN, SAUNDERS, PHILADELPHIA, PA, US, vol. 9, no. 4, 1 April 2008 (2008-04-01), pages 35, XP025871409, ISSN: 1526-5900, [retrieved on 20080401], DOI: 10.1016/J.JPAIN.2008.01.157 *
See also references of WO2009085778A1 *

Also Published As

Publication number Publication date
CA2709950A1 (fr) 2009-07-09
WO2009085778A1 (fr) 2009-07-09
EP2224915A1 (fr) 2010-09-08
AU2008343267A1 (en) 2009-07-09

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20100624

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA MK RS

RIN1 Information on inventor provided before grant (corrected)

Inventor name: STAUFFER, JOSEPH

Inventor name: JOHNSON, FRANK

Inventor name: TANG, LIJUAN

Inventor name: BOEHM, GARTH

Inventor name: MATTHEWS, FRANK

Inventor name: LIANG, ALFRED

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20140102

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 45/06 20060101ALI20131217BHEP

Ipc: A61K 31/485 20060101ALI20131217BHEP

Ipc: A61K 9/50 20060101AFI20131217BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20140801