EP2248604A1 - Dispositif de tri de capsules de médicaments cylindriques dont la géométrie est défectueuse - Google Patents
Dispositif de tri de capsules de médicaments cylindriques dont la géométrie est défectueuse Download PDFInfo
- Publication number
- EP2248604A1 EP2248604A1 EP10157941A EP10157941A EP2248604A1 EP 2248604 A1 EP2248604 A1 EP 2248604A1 EP 10157941 A EP10157941 A EP 10157941A EP 10157941 A EP10157941 A EP 10157941A EP 2248604 A1 EP2248604 A1 EP 2248604A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- disc
- capsules
- holes
- pot
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002775 capsule Substances 0.000 title claims abstract description 78
- 239000003814 drug Substances 0.000 title claims abstract description 78
- 230000002950 deficient Effects 0.000 claims abstract description 13
- 229940079593 drug Drugs 0.000 claims description 58
- 238000007664 blowing Methods 0.000 claims description 9
- 238000005520 cutting process Methods 0.000 claims description 3
- 238000004806 packaging method and process Methods 0.000 description 8
- 101100298225 Caenorhabditis elegans pot-2 gene Proteins 0.000 description 6
- 230000006378 damage Effects 0.000 description 4
- 230000033001 locomotion Effects 0.000 description 4
- 239000013590 bulk material Substances 0.000 description 3
- 230000000284 resting effect Effects 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000006386 neutralization reaction Methods 0.000 description 2
- 238000013459 approach Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 238000009966 trimming Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B13/00—Grading or sorting solid materials by dry methods, not otherwise provided for; Sorting articles otherwise than by indirectly controlled devices
- B07B13/04—Grading or sorting solid materials by dry methods, not otherwise provided for; Sorting articles otherwise than by indirectly controlled devices according to size
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/077—Manufacturing capsule shells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/06—Cone or disc shaped screens
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B13/00—Grading or sorting solid materials by dry methods, not otherwise provided for; Sorting articles otherwise than by indirectly controlled devices
- B07B13/003—Separation of articles by differences in their geometrical form or by difference in their physical properties, e.g. elasticity, compressibility, hardness
Definitions
- the invention relates to a device for sorting out defective cylindrical medicament capsules.
- Drug capsules are used for oral administration of liquid or powdered medicines, which are to take effect with a time delay. They generally consist of gelatin capsules in which the medicament is enclosed, and comprise a centrally arranged, hollow-cylindrical region which is closed on both sides in the axial direction by hollow caps and filled internally with the medicament.
- the drug capsules are first collected after their preparation and filling in bags, possibly stored temporarily and transferred individually for single administration by means of packaging machines in the wells of blister packs, which consist of a thermoformed plastic film.
- the cups are superimposed for the individual withdrawal of the drug capsules covered by an aluminum foil and sealed, is pressed through which the respective drug capsule to be removed with proportionate destruction of the aluminum foil and deformation of the respective cup. This can be very hygienic and has proven very successful.
- the invention is based on the object to show a device that allows fully automatic and safe to detect all fully unusable by deformations drug capsules and excrete fully automatically.
- the invention should be suitable in addition to the sorting out of defective drug capsules for sorting out other cylindrical bodies whose diameter exceeds at least at one point in one direction an arbitrarily definable nominal value.
- the device for sorting defective cylindrical medicament capsules having a diameter exceeding in diameter in at least one direction comprises a fixed obliquely inclined pot for receiving the medicament capsules.
- the pot is closed at the bottom by a disk rotating about an axis.
- the disc is penetrated by a plurality of parallel to the axis extending and funnel-shaped upwardly extending holes.
- the holes have an arbitrary minimum diameter that matches all holes.
- About the storage of the disc at least one directed from below against the holes blowing nozzle is provided and on the opposite side of the disc of the blowing nozzle is provided at least one suction device for defective drug capsules.
- the funnel-shaped upwardly extending holes are mounted distributed over the surface of the disc and inclined that the entered as bulk material in the pot drug capsules, stimulated by rotation of the disc in the dormant pot, can automatically fall into the holes. Impeccable drug capsules fall through the holes all the way through and are fed to the packaging device.
- Faulty drug capsules that have a critical diameter violation at at least one circumferential location, however, jam in the holes. They can therefore not fall through the holes and are instead led out of the obliquely upwardly rotating disc from the field of auflastenden capsule bed up in a region in which the subhab of the disc is a blowing nozzle for compressed air and above the disc a suction device for faulty drug capsules. The faulty drug capsules are thereby up and out of the holes in the Suction flow of the suction blown in and transported away through this and disposed of.
- the pot is provided below the disc with a parallel to the disc extending, fixed bottom, wherein the distance A of the disc from the bottom is smaller than half the diameter of the drug capsules, which is about half the diameter corresponds to the smallest bore diameter, wherein the bottom above the axis arranged in the raceway of the bores ejection opening for the capsules and wherein the blowing nozzle is arranged in the direction of rotation of the disc following the ejection opening.
- the area where the good drug capsules are ejected is of reduced size, which facilitates the control of continuous drainage.
- the device is extremely simple. Nevertheless, it is fully automatic large quantities of medicament capsule according to qualitative standards safely and completely check for critical diameter exceedances in any direction and eliminate defective drug capsules reliable.
- the diameter deviations as such can be done by hand the diameter of the holes arbitrarily define so that a blockage downstream packaging machine is no longer to be feared.
- a likewise the automatic testing and excretion of defective drug capsules enabling device is indeed in the EP 2 130 612 A2 described.
- this document is only prior art under Art. 54 (3) EPC.
- the parts of the device which come into contact with the medicament capsules are made of metal, preferably of stainless steel, which makes it possible to easily meet the hygienic standards prescribed for pharmaceutical areas in the long term and at the same time to achieve an electrostatic neutralization of the medicament capsules.
- metal preferably of stainless steel
- electrostatic forces can cause a large number of drug capsules to fuse into a chain, hindering the separation necessary for separate packaging of the drug capsules.
- the avoidance of fires is promoted by the electrostatic neutralization.
- the drug capsules to be controlled can be supplied in a particularly simple manner, defective drug capsules can easily be removed via the suction system and any faults can be easily remedied. Also, the cleaning and replacement of the pot and / or the disc against another is particularly easy. Both parts are very easily stored and expediently fixed by quick-release fasteners.
- a rotatable carrier is expediently mounted for the disc, wherein the driver and the disc are releasably connected by a quick-release tool-less.
- the replacement of the disc against another or for the purpose of cleaning is thereby particularly simple.
- the driver can be formed by a stub shaft and / or flange and the quick release by a manually operable clamping screw.
- the bores should have a cylindrical wall portion with a length L that is at least 0.5 times the length of the drug capsules. This ensures that they are secured after falling into the holes therein from damage and are guided freely movable.
- the holes should have a length D that is 0.8 to 1.4 times the length of the drug capsules. This helps to prevent damage to existing drug capsules in the holes by not yet recorded in the holes drug capsules, which circulate as bulk material and burden the recorded drug capsules.
- the holes should have a trumpet like rounded rounded upwardly expanded cross-section. As a result, the drug capsules are able to slide into the holes particularly easily and without damage.
- the holes should have a largest diameter, which is 0.7 to 1.5 times the length of the drug capsules. This prevents the drug capsules from jamming each other in the holes.
- the holes are expediently arranged so close to each other that they at the funnel-shaped enlarged end in limit common cutting edges.
- the top of the disc is formed in such a training in the region of the junctions of the holes by sharp edges, forming a merge honeycomb pattern.
- the nozzles can be activated by a sensor. They then only come into operation when a hole is blocked by a jammed and thus faulty drug capsule. In terms of compressed air consumption can be achieved by a significant savings.
- Suitable sensors may be formed by photocells.
- the suction device is preceded by a scraper for drug capsules, which are still on top of the disc. This prevents "good" drug capsules, which for some reason have not gotten into a hole, are disposed of via the suction device.
- the scraper may be formed by a brush rotating in opposite directions with respect to the rotation of the disc, which calls loosely resting on the disc, uncontrolled drug capsules back into the Kotroll Scheme the disc.
- the brush should have a soft fiber trimming to prevent the medication capsules from being damaged by touching the brush.
- Fig. 1 shows an apparatus for sorting out defective cylindrical medicament capsules 1 of a diameter exceeding a nominal value in at least one direction.
- the nominal value exceeding diameter is not shown.
- the device consists of a resting on a machine frame pot 2, whose bottom with an imaginary horizontal plane forms an angle B of about 30 °.
- a motor 5 rotates about its axis 4 disc 5 is arranged at a small distance A from 1 to 2 mm above the bottom 3.
- the disc is penetrated by a variety of holes 6, which are extend parallel to the axis 4.
- the fixed, obliquely inclined pot 2 is intended for receiving the drug capsules 1.
- the holes 6 are funnel-shaped flared upwards and have a matching, arbitrary set, smallest diameter, wherein the distance A of the disc 5 from the bottom 3 is smaller than half the diameter of the drug capsules 1.
- the bottom 3 points along the slope above the storage the disc 5 at least one arranged in the running path of the holes 6 ejection opening 7 and in the direction of rotation of the disc 5 on the discharge opening 7 following at least one directed from below against the holes blowing nozzle 8.
- On the opposite side of the disc 5 of the blowing nozzle 8 at least one suction device 9 is provided for defective drug capsules 1.
- a rotatable carrier 10 is mounted for the disc 5, wherein the driver 10 and the disc 5 are releasably connected to each other by a quick release tool-free.
- the driver 10 is formed by a stub shaft and / or flange, which allows the disc rotationally symmetrical and secure against rotation.
- Fig. 2a shows a pot 2 in an axially parallel plan view, in which a disc 5 is inserted with holes 6, which are assigned to each other in a regular honeycomb pattern.
- Fig. 2b shows a pot in an axially parallel plan view, in which a disc 5 is inserted with holes 6 which are arranged on circular paths which surround the axis of rotation concentrically. This will become more To get control over the drug capsules.
- Fig. 3 shows a section of the inserted into the pot 2 disc 5 in longitudinal section.
- the holes 6 in this case have a cylindrical wall portion with a length L which is at least 0.5 times as large as the length of the drug capsules 1. Falling into the holes 6 drug capsules 1 are thereby secured against jamming of the disc 5 on the stationary, taken ramp-like rising bottom of the pot 3 and fall after reaching the ejection opening 7 safely down out of the holes 6 and through the ejection opening 7 through into a collecting funnel 12, through which they are not shown packaging system supplied.
- the holes 6 have a total length D, which is 0.8 to 1.4 times as large as the length of the drug capsules 1, in this case 1.1 times as large.
- the drug capsules 1 which have already fallen into the bores 6 are thereby protected against transverse forces, which can result if the medicament capsules charging on the lower part of the disc 5 of the disc as bulk material are circulated through the obliquely mounted, rotating disc 5. They are thus easily movably received in the holes 6.
- the holes 6 have a trumpet funnel rounded rounded upwards cross-section. At the funnel-shaped widened end, they bound each other in common cut edges 11 which form a honeycomb pattern, as in FIG Fig. 2a . 2b and 3 is recognizable.
- the cut edges 11 have, based on the top of the disc 5, an uneven course, see Fig. 3 ,
- the blast nozzles 8 are activated by sensors, such that only when a clogged hole passes a tuyere 8, a blast of compressed air directed from below against the bore 6 and the drug capsule 1 jammed therein is blown up in suction device 9 and removed.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Manufacturing & Machinery (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Feeding Of Articles To Conveyors (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE200910015352 DE102009015352B4 (de) | 2009-03-27 | 2009-03-27 | Vorrichtung zum Aussortieren von fehlerhaften, zylindrischen Medikamentenkapseln |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2248604A1 true EP2248604A1 (fr) | 2010-11-10 |
| EP2248604B1 EP2248604B1 (fr) | 2013-05-01 |
Family
ID=42651133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20100157941 Not-in-force EP2248604B1 (fr) | 2009-03-27 | 2010-03-26 | Dispositif de tri de capsules de médicaments cylindriques dont la géométrie est défectueuse |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP2248604B1 (fr) |
| DE (1) | DE102009015352B4 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302412A (zh) * | 2011-06-24 | 2012-01-04 | 浙江大之医药胶囊有限公司 | 一种胶囊切屑收集装置 |
| CN107931128A (zh) * | 2017-12-22 | 2018-04-20 | 潘苏枫 | 一种改善型胶囊筛选机 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2506443A (en) * | 2012-10-01 | 2014-04-02 | Nicholas Basil Baird | Separator formations |
| CN106078483B (zh) * | 2016-06-07 | 2018-05-08 | 新昌县恒丰胶囊有限公司 | 一种胶囊抛光分选机及使用方法 |
| CN108126957A (zh) * | 2017-12-21 | 2018-06-08 | 潘金槐 | 一种胶囊自动分拣装置 |
| EP3771500A1 (fr) * | 2019-07-31 | 2021-02-03 | A O Ideas GmbH | Dispositif de séparation et procédé de fonctionnement |
| CN110575958B (zh) * | 2019-09-28 | 2020-06-23 | 张效法 | 一种制药生产线用空壳胶囊排除装置 |
| CN112643924B (zh) * | 2020-12-19 | 2022-10-21 | 重庆市金盾橡胶制品有限公司 | 一种高效率橡胶颗粒多级筛分装置 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3997058A (en) | 1976-01-29 | 1976-12-14 | Smithkline Corporation | Capsule inspection machine |
| FR2916662A1 (fr) | 2007-05-30 | 2008-12-05 | Floplast Entpr Unipersonnelle | Machine de tri automatique des gelules defectueuses en fonction de leur diametre et de leur poids |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2722499A1 (de) * | 1977-05-18 | 1978-11-23 | Bosch Gmbh Robert | Vorrichtung zum sortieren von hartgelatinekapseln |
| DE7737603U1 (de) * | 1977-12-09 | 1978-03-23 | Seidenader, Robert, 8000 Muenchen | Sortiermaschine fuer dragees, insbesondere fuer oblong-tabletten |
| FR2548055B1 (fr) * | 1983-06-28 | 1985-12-20 | Kalfon Pierre Olivier | Dispositif pour l'elimination des comprimes casses, notamment pour l'industrie pharmaceutique |
| DE102008026285B3 (de) * | 2008-06-02 | 2009-07-02 | Sittel, Jürgen | Vorrichtung zum Aussortieren von fehlerhaften, zylindrischen Medikamentenkapseln |
-
2009
- 2009-03-27 DE DE200910015352 patent/DE102009015352B4/de not_active Expired - Fee Related
-
2010
- 2010-03-26 EP EP20100157941 patent/EP2248604B1/fr not_active Not-in-force
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3997058A (en) | 1976-01-29 | 1976-12-14 | Smithkline Corporation | Capsule inspection machine |
| FR2916662A1 (fr) | 2007-05-30 | 2008-12-05 | Floplast Entpr Unipersonnelle | Machine de tri automatique des gelules defectueuses en fonction de leur diametre et de leur poids |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302412A (zh) * | 2011-06-24 | 2012-01-04 | 浙江大之医药胶囊有限公司 | 一种胶囊切屑收集装置 |
| CN107931128A (zh) * | 2017-12-22 | 2018-04-20 | 潘苏枫 | 一种改善型胶囊筛选机 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE102009015352A1 (de) | 2010-09-30 |
| EP2248604B1 (fr) | 2013-05-01 |
| DE102009015352B4 (de) | 2013-03-07 |
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