EP2275128A3 - Streptococcus-pneumoniae-Vakzine auf Proteinbasis - Google Patents
Streptococcus-pneumoniae-Vakzine auf Proteinbasis Download PDFInfo
- Publication number
- EP2275128A3 EP2275128A3 EP10011328A EP10011328A EP2275128A3 EP 2275128 A3 EP2275128 A3 EP 2275128A3 EP 10011328 A EP10011328 A EP 10011328A EP 10011328 A EP10011328 A EP 10011328A EP 2275128 A3 EP2275128 A3 EP 2275128A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- protein
- streptococcus pneumoniae
- pneumoniae vaccines
- based streptococcus
- vaccines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000193998 Streptococcus pneumoniae Species 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 title 1
- 102000005416 ATP-Binding Cassette Transporters Human genes 0.000 abstract 1
- 108010006533 ATP-Binding Cassette Transporters Proteins 0.000 abstract 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36898102P | 2002-04-02 | 2002-04-02 | |
| EP03745390A EP1490104B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus pneumoniae vakzine auf proteinbasis |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP03745390.9 Division | 2003-04-01 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP2275128A2 EP2275128A2 (de) | 2011-01-19 |
| EP2275128A3 true EP2275128A3 (de) | 2011-04-06 |
| EP2275128B1 EP2275128B1 (de) | 2013-10-16 |
Family
ID=28675560
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10011322A Withdrawn EP2275122A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP03745390A Expired - Lifetime EP1490104B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus pneumoniae vakzine auf proteinbasis |
| EP10011321.6A Expired - Lifetime EP2275121B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011320A Withdrawn EP2275120A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011327A Expired - Lifetime EP2275127B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011325A Withdrawn EP2275125A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011328.1A Expired - Lifetime EP2275128B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011326A Withdrawn EP2275126A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011324A Withdrawn EP2275124A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011323A Expired - Lifetime EP2275123B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
Family Applications Before (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10011322A Withdrawn EP2275122A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP03745390A Expired - Lifetime EP1490104B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus pneumoniae vakzine auf proteinbasis |
| EP10011321.6A Expired - Lifetime EP2275121B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011320A Withdrawn EP2275120A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011327A Expired - Lifetime EP2275127B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011325A Withdrawn EP2275125A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10011326A Withdrawn EP2275126A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011324A Withdrawn EP2275124A3 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
| EP10011323A Expired - Lifetime EP2275123B1 (de) | 2002-04-02 | 2003-04-01 | Streptococcus-pneumoniae-Vakzine auf Proteinbasis |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7504110B2 (de) |
| EP (10) | EP2275122A3 (de) |
| AU (1) | AU2003242955B2 (de) |
| CA (1) | CA2481107A1 (de) |
| IL (1) | IL164242A0 (de) |
| WO (1) | WO2003082183A2 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8691243B2 (en) | 2002-04-02 | 2014-04-08 | Ben-Gurion University Of The Negev Research And Development Authority | Protein-based Streptococcus pneumoniae vaccine |
| US20090252756A1 (en) * | 2002-04-02 | 2009-10-08 | Yaffa Mizrachi-Nebenzahl | Protein-based streptococcus pneumoniae vaccines |
| TWI236173B (en) * | 2004-02-13 | 2005-07-11 | Ind Tech Res Inst | Manufacturing method and device for organic thin film transistor |
| WO2006084467A1 (en) * | 2005-02-11 | 2006-08-17 | Ace Biosciences A/S | Surface-located streptococcus pneumoniae polypeptides |
| PT103450B (pt) * | 2006-03-13 | 2008-09-19 | Univ Do Porto | Vacina contra streptococcus agalactiae usando como antigénio alvo a proteína gliceraldeído-3-fosfato desidrogenase (gapdh) produzida pela bactéria, na sua forma nativa ou recombinante |
| EP2012825B1 (de) | 2006-03-30 | 2013-07-17 | Ben-Gurion University of the Negev Research and Development Authority | Verfahren und zusammensetzungen zur prävention und behandlung von infektionen mit streptococcus pneumoniae |
| GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| CN102015651B (zh) | 2008-03-03 | 2014-12-31 | Irm责任有限公司 | 作为tlr活性调节剂的化合物和组合物 |
| BRPI0922132A2 (pt) | 2008-12-03 | 2018-10-23 | Protea Vaccine Tech Ltd | fragmentos glutamil trna sintetase (gts). |
| JP5867952B2 (ja) | 2009-06-10 | 2016-02-24 | ノバルティス アーゲー | ベンゾナフチリジン含有ワクチン |
| WO2010150242A2 (en) * | 2009-06-25 | 2010-12-29 | Protea Vaccine Technologies Ltd. | Immunogenic streptococcus pneumoniae peptides and peptide-multimers |
| RU2580299C2 (ru) | 2009-06-29 | 2016-04-10 | Дженосеа Биосайенсиз, Инк. | Вакцины и композиции, направленные против streptococcus pneumoniae |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| WO2011027222A2 (en) | 2009-09-02 | 2011-03-10 | Novartis Ag | Immunogenic compositions including tlr activity modulators |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| WO2011067758A2 (en) | 2009-12-02 | 2011-06-09 | Protea Vaccine Technologies Ltd. | Immunogenic fragments and multimers from streptococcus pneumoniae proteins |
| BR112012014624A8 (pt) | 2009-12-15 | 2017-12-26 | Novartis Ag | suspensão homogênea de compostos de imunopotenciação e usos dos destes |
| EA031379B1 (ru) | 2010-03-23 | 2018-12-28 | Новартис Аг | Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний |
| WO2011128892A2 (en) * | 2010-04-12 | 2011-10-20 | Protea Vaccine Technologies Ltd. | Modified forms of pneumococcal surface immunogenic protein b (psipb) |
| WO2012100233A1 (en) | 2011-01-20 | 2012-07-26 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
| CA2897020A1 (en) | 2012-01-20 | 2013-07-25 | Genocea Biosciences, Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
| JP2015510872A (ja) | 2012-03-07 | 2015-04-13 | ノバルティス アーゲー | Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ抗原の増強された製剤 |
| TWI477282B (zh) | 2012-05-23 | 2015-03-21 | Univ Ishou | 致熱原性外毒素ｂ胜肽疫苗 |
| BR112015018014A2 (pt) | 2013-02-01 | 2017-07-11 | Glaxosmithkline Biologicals Sa | liberação intradérmica de composições imunológicas compreendendo agonistas do receptor do tipo toll |
| JP2020502056A (ja) * | 2016-11-13 | 2020-01-23 | イマジン ファーマ | 糖尿病、高血圧および高コレステロール血症を治療するための組成物および方法 |
| JP7362667B2 (ja) | 2018-02-12 | 2023-10-17 | イニミューン・コーポレーション | Ｔｏｌｌ様受容体リガンド |
| JP2023547677A (ja) | 2020-11-04 | 2023-11-13 | エリゴ・バイオサイエンス | キューティバクテリウム・アクネス組換えファージ、その産生方法及び使用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6217884B1 (en) * | 1991-11-14 | 2001-04-17 | The United States Of America As Represented By The Department Of Health And Human Services | Streptococcus pneumoniae 37-kDa surface adhesin a protein |
| WO2002022168A2 (en) * | 2000-09-15 | 2002-03-21 | Glaxosmithkline Biologicals S.A. | Vaccine against streptococcus pneumoniae |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| FI933580A7 (fi) * | 1991-02-15 | 1993-10-13 | Uab Research Foundation | Pneumokokkiproteiinin rakennegeeni |
| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US6197300B1 (en) * | 1997-08-12 | 2001-03-06 | Smithkline Beecham Corporation | ftsZ |
| EP0964921A4 (de) * | 1997-11-05 | 2002-01-23 | Smithkline Beecham Corp | Neue ers aus streptococcus |
| WO1999027074A1 (en) * | 1997-11-20 | 1999-06-03 | Smithkline Beecham Corporation | Novel tig |
| GB0107658D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
| EP2277897A1 (de) * | 2001-04-16 | 2011-01-26 | Wyeth Holdings Corporation | Polypeptideantigene codierende offene Leseraster aus Streptococcus pneumoniae und Verwendungen davon |
| JP2005519580A (ja) * | 2001-05-16 | 2005-07-07 | アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ | 非ヒト動物由来のヒト抗肺炎球菌抗体 |
| US20090252756A1 (en) * | 2002-04-02 | 2009-10-08 | Yaffa Mizrachi-Nebenzahl | Protein-based streptococcus pneumoniae vaccines |
-
2003
- 2003-04-01 EP EP10011322A patent/EP2275122A3/de not_active Withdrawn
- 2003-04-01 EP EP03745390A patent/EP1490104B1/de not_active Expired - Lifetime
- 2003-04-01 EP EP10011321.6A patent/EP2275121B1/de not_active Expired - Lifetime
- 2003-04-01 EP EP10011320A patent/EP2275120A3/de not_active Withdrawn
- 2003-04-01 EP EP10011327A patent/EP2275127B1/de not_active Expired - Lifetime
- 2003-04-01 EP EP10011325A patent/EP2275125A3/de not_active Withdrawn
- 2003-04-01 EP EP10011328.1A patent/EP2275128B1/de not_active Expired - Lifetime
- 2003-04-01 EP EP10011326A patent/EP2275126A3/de not_active Withdrawn
- 2003-04-01 IL IL16424203A patent/IL164242A0/xx unknown
- 2003-04-01 CA CA002481107A patent/CA2481107A1/en not_active Abandoned
- 2003-04-01 AU AU2003242955A patent/AU2003242955B2/en not_active Ceased
- 2003-04-01 WO PCT/IL2003/000271 patent/WO2003082183A2/en not_active Ceased
- 2003-04-01 EP EP10011324A patent/EP2275124A3/de not_active Withdrawn
- 2003-04-01 EP EP10011323A patent/EP2275123B1/de not_active Expired - Lifetime
-
2004
- 2004-09-30 US US10/953,513 patent/US7504110B2/en not_active Expired - Fee Related
-
2009
- 2009-01-30 US US12/363,383 patent/US20090148470A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6217884B1 (en) * | 1991-11-14 | 2001-04-17 | The United States Of America As Represented By The Department Of Health And Human Services | Streptococcus pneumoniae 37-kDa surface adhesin a protein |
| WO2002022168A2 (en) * | 2000-09-15 | 2002-03-21 | Glaxosmithkline Biologicals S.A. | Vaccine against streptococcus pneumoniae |
Non-Patent Citations (5)
| Title |
|---|
| BRILES D E ET AL: "INTRANASAL IMMUNIZATION OF MICE WITH A MIXTURE OF THE PNEUMOCOCCAL PROTEINS PSAA AND PSPA IS HIGHLY PROTECTIVE AGAINST NASOPHARYNGEAL CARRIAGE OF STREPTOCOCCUS PNEUMONIAE", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, US, vol. 68, no. 2, 1 February 2000 (2000-02-01), pages 796 - 800, XP001064849, ISSN: 0019-9567, DOI: 10.1128/IAI.68.2.796-800.2000 * |
| JEDRZEJAS M J: "PNEUMOCOCCAL VIRULENCE FACTORS: STRUCTURE AND FUNCTION", MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 65, no. 2, 1 June 2001 (2001-06-01), pages 187 - 207, XP001100692, ISSN: 1092-2172, DOI: 10.1128/MMBR.65.2.187-207.2001 * |
| JOHNSON S E ET AL: "INHIBITION OF PNEUMOCOCCAL CARRIAGE IN MICE BY SUBCUTANEOUS IMMUNIZATION WITH PEPTIDES FROM THE COMMON SURFACE PROTEIN PNEUMOCOCCAL SURFACE ADHESIN A", JOURNAL OF INFECTIOUS DISEASES, UNIVERSITY OF CHICAGO PRESS, CHICAGO, IL, vol. 185, 31 January 2002 (2002-01-31), pages 489 - 496, XP001246751, ISSN: 0022-1899, DOI: 10.1086/338928 * |
| LAWRENCE MICHAEL C ET AL: "The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein", STRUCTURE (LONDON), vol. 6, no. 12, 15 December 1998 (1998-12-15), pages 1553 - 1561, XP002623533, ISSN: 0969-2126 * |
| SEO JUN-YOUNG ET AL: "Cross-protective immunity of mice induced by oral immunization with pneumococcal surface adhesin A encapsulated in microspheres", INFECTION AND IMMUNITY, vol. 70, no. 3, March 2002 (2002-03-01), pages 1143 - 1149, XP002623532, ISSN: 0019-9567 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2275126A2 (de) | 2011-01-19 |
| EP1490104A4 (de) | 2006-02-08 |
| EP2275125A3 (de) | 2011-03-09 |
| EP2275122A3 (de) | 2011-05-18 |
| US20090148470A1 (en) | 2009-06-11 |
| US7504110B2 (en) | 2009-03-17 |
| EP2275120A3 (de) | 2011-06-08 |
| EP2275128A2 (de) | 2011-01-19 |
| EP2275121A3 (de) | 2011-04-13 |
| EP2275120A2 (de) | 2011-01-19 |
| EP2275124A2 (de) | 2011-01-19 |
| WO2003082183A2 (en) | 2003-10-09 |
| EP2275123A2 (de) | 2011-01-19 |
| EP2275127B1 (de) | 2012-09-19 |
| EP2275123A3 (de) | 2011-05-18 |
| EP2275127A2 (de) | 2011-01-19 |
| EP2275121B1 (de) | 2013-06-12 |
| EP2275126A3 (de) | 2011-04-27 |
| EP2275123B1 (de) | 2012-12-05 |
| AU2003242955A1 (en) | 2003-10-13 |
| EP2275127A3 (de) | 2011-03-23 |
| EP2275128B1 (de) | 2013-10-16 |
| EP2275121A2 (de) | 2011-01-19 |
| AU2003242955B2 (en) | 2009-04-09 |
| CA2481107A1 (en) | 2003-10-09 |
| EP1490104A2 (de) | 2004-12-29 |
| EP2275122A2 (de) | 2011-01-19 |
| EP2275125A2 (de) | 2011-01-19 |
| WO2003082183A3 (en) | 2004-01-15 |
| EP1490104B1 (de) | 2012-06-06 |
| IL164242A0 (en) | 2005-12-18 |
| US20050196415A1 (en) | 2005-09-08 |
| EP2275124A3 (de) | 2011-03-23 |
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Inventor name: MIZRACHI NEBENZAHL, YAFFA |
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