EP2286839A3 - Behandlung von Fettleibigkeit und von verwandten Krankheiten - Google Patents

Behandlung von Fettleibigkeit und von verwandten Krankheiten Download PDF

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Publication number
EP2286839A3
EP2286839A3 EP10178803.2A EP10178803A EP2286839A3 EP 2286839 A3 EP2286839 A3 EP 2286839A3 EP 10178803 A EP10178803 A EP 10178803A EP 2286839 A3 EP2286839 A3 EP 2286839A3
Authority
EP
European Patent Office
Prior art keywords
obesity
treatment
related diseases
agents directed
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10178803.2A
Other languages
English (en)
French (fr)
Other versions
EP2286839A2 (de
Inventor
Jonathan D. Roth
Christen M. Anderson
Alain Baron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amylin Pharmaceuticals LLC
AstraZeneca Pharmaceuticals LP
Original Assignee
Amylin Pharmaceuticals LLC
AstraZeneca Pharmaceuticals LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36336990&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP2286839(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amylin Pharmaceuticals LLC, AstraZeneca Pharmaceuticals LP filed Critical Amylin Pharmaceuticals LLC
Publication of EP2286839A2 publication Critical patent/EP2286839A2/de
Publication of EP2286839A3 publication Critical patent/EP2286839A3/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2264—Obesity-gene products, e.g. leptin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2207—Gastrins; Cholecystokinins [CCK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
EP10178803.2A 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und von verwandten Krankheiten Withdrawn EP2286839A3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62435704P 2004-11-01 2004-11-01
EP09003342.4A EP2127676A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und mit Fettleibigkeit zusammenhängenden Erkrankungen und Störungen
EP05820773.9A EP1814590B2 (de) 2004-11-01 2005-11-01 Behandlung von fettsucht und verbundenen erkrankungen

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP05820773.9 Division 2005-11-01
EP09003342.4 Division 2009-03-06

Publications (2)

Publication Number Publication Date
EP2286839A2 EP2286839A2 (de) 2011-02-23
EP2286839A3 true EP2286839A3 (de) 2013-09-04

Family

ID=36336990

Family Applications (6)

Application Number Title Priority Date Filing Date
EP10178805.7A Withdrawn EP2286840A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und von verwandten Krankheiten
EP10178800.8A Withdrawn EP2286838A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und von verwandten Krankheiten
EP05820773.9A Expired - Lifetime EP1814590B2 (de) 2004-11-01 2005-11-01 Behandlung von fettsucht und verbundenen erkrankungen
EP09003342.4A Withdrawn EP2127676A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und mit Fettleibigkeit zusammenhängenden Erkrankungen und Störungen
EP10178797.6A Withdrawn EP2286837A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und von verwandten Krankheiten
EP10178803.2A Withdrawn EP2286839A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und von verwandten Krankheiten

Family Applications Before (5)

Application Number Title Priority Date Filing Date
EP10178805.7A Withdrawn EP2286840A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und von verwandten Krankheiten
EP10178800.8A Withdrawn EP2286838A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und von verwandten Krankheiten
EP05820773.9A Expired - Lifetime EP1814590B2 (de) 2004-11-01 2005-11-01 Behandlung von fettsucht und verbundenen erkrankungen
EP09003342.4A Withdrawn EP2127676A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und mit Fettleibigkeit zusammenhängenden Erkrankungen und Störungen
EP10178797.6A Withdrawn EP2286837A3 (de) 2004-11-01 2005-11-01 Behandlung von Fettleibigkeit und von verwandten Krankheiten

Country Status (14)

Country Link
US (1) US20090156474A1 (de)
EP (6) EP2286840A3 (de)
JP (1) JP4926069B2 (de)
KR (1) KR101123549B1 (de)
CN (1) CN101094689B (de)
AT (1) ATE427759T1 (de)
BR (1) BRPI0518241A (de)
CA (2) CA2584806C (de)
DE (1) DE602005013811D1 (de)
DK (1) DK1814590T4 (de)
ES (1) ES2325773T5 (de)
IL (1) IL182764A (de)
WO (1) WO2006052608A2 (de)
ZA (1) ZA200704239B (de)

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ES2602789T3 (es) 2007-02-09 2017-02-22 Ocera Therapeutics, Inc. Productos intermedios conectores para la síntesis de moduladores macrocíclicos del receptor de la grelina
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KR20240037175A (ko) 2016-05-16 2024-03-21 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
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ZA200704239B (en) 2008-04-30
EP2286838A2 (de) 2011-02-23
EP2286839A2 (de) 2011-02-23
WO2006052608A3 (en) 2006-12-07
KR20070089683A (ko) 2007-08-31
ATE427759T1 (de) 2009-04-15
KR101123549B1 (ko) 2012-04-18
DK1814590T4 (da) 2014-02-24
EP2286837A3 (de) 2013-09-04
CN101094689A (zh) 2007-12-26
EP1814590B2 (de) 2013-12-11
CA2584806A1 (en) 2006-05-18
EP2286840A3 (de) 2013-09-04
CA2628051A1 (en) 2007-05-18
US20090156474A1 (en) 2009-06-18
IL182764A (en) 2014-05-28
EP1814590B1 (de) 2009-04-08
JP2008518963A (ja) 2008-06-05
EP2286838A3 (de) 2013-09-04
CA2584806C (en) 2014-06-17
EP1814590A2 (de) 2007-08-08
ES2325773T5 (es) 2014-02-24

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