EP2298449A3 - Vorrichtung zur Analyse - Google Patents

Vorrichtung zur Analyse Download PDF

Info

Publication number
EP2298449A3
EP2298449A3 EP10183084A EP10183084A EP2298449A3 EP 2298449 A3 EP2298449 A3 EP 2298449A3 EP 10183084 A EP10183084 A EP 10183084A EP 10183084 A EP10183084 A EP 10183084A EP 2298449 A3 EP2298449 A3 EP 2298449A3
Authority
EP
European Patent Office
Prior art keywords
analytical device
multiplicity
chamber
channel
analytical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10183084A
Other languages
English (en)
French (fr)
Other versions
EP2298449B1 (de
EP2298449A2 (de
Inventor
Hans-Peter Wahl
Emad Sarofim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Original Assignee
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG, Roche Diagnostics GmbH filed Critical F Hoffmann La Roche AG
Priority to EP10183084A priority Critical patent/EP2298449B1/de
Publication of EP2298449A2 publication Critical patent/EP2298449A2/de
Publication of EP2298449A3 publication Critical patent/EP2298449A3/de
Application granted granted Critical
Publication of EP2298449B1 publication Critical patent/EP2298449B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50851—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP10183084A 2006-07-14 2007-07-13 Vorrichtung zur Analyse Not-in-force EP2298449B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10183084A EP2298449B1 (de) 2006-07-14 2007-07-13 Vorrichtung zur Analyse

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06014678A EP1886727A1 (de) 2006-07-14 2006-07-14 Vorrichtung zur Analyse
EP07765203A EP2054155B1 (de) 2006-07-14 2007-07-13 Analysegerät
EP10183084A EP2298449B1 (de) 2006-07-14 2007-07-13 Vorrichtung zur Analyse

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP07765203A Division-Into EP2054155B1 (de) 2006-07-14 2007-07-13 Analysegerät
EP07765203.0 Division 2007-07-13

Publications (3)

Publication Number Publication Date
EP2298449A2 EP2298449A2 (de) 2011-03-23
EP2298449A3 true EP2298449A3 (de) 2011-05-11
EP2298449B1 EP2298449B1 (de) 2013-01-02

Family

ID=37622007

Family Applications (3)

Application Number Title Priority Date Filing Date
EP06014678A Withdrawn EP1886727A1 (de) 2006-07-14 2006-07-14 Vorrichtung zur Analyse
EP10183084A Not-in-force EP2298449B1 (de) 2006-07-14 2007-07-13 Vorrichtung zur Analyse
EP07765203A Not-in-force EP2054155B1 (de) 2006-07-14 2007-07-13 Analysegerät

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP06014678A Withdrawn EP1886727A1 (de) 2006-07-14 2006-07-14 Vorrichtung zur Analyse

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP07765203A Not-in-force EP2054155B1 (de) 2006-07-14 2007-07-13 Analysegerät

Country Status (3)

Country Link
EP (3) EP1886727A1 (de)
JP (1) JP2009543548A (de)
WO (1) WO2008006617A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0715170D0 (en) * 2007-08-03 2007-09-12 Enigma Diagnostics Ltd Reaction vessel
WO2012019119A1 (en) * 2010-08-06 2012-02-09 Instantlabs Medical Diagnostics Corporation Systems, devices and methods for monitoring and detection of chemical reactions
EP2647435B1 (de) * 2012-04-05 2020-08-05 ThinXXS Microtechnology AG Anordnung aus einer flusszelle und einem temperierelement
WO2013184398A1 (en) 2012-06-05 2013-12-12 3M Innovative Properties Company Multiwell plate
WO2013184397A1 (en) * 2012-06-05 2013-12-12 3M Innovative Properties Company Apparatus and method for processing a sample

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
WO2002043864A2 (en) * 2000-11-03 2002-06-06 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
EP1418243A2 (de) * 2002-10-31 2004-05-12 Hewlett-Packard Development Company, L.P. Mikrofluidsystem zur Analyse von Nukleinsäure

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1339653C (en) 1986-02-25 1998-02-03 Larry J. Johnson Appartus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
EP0318256B1 (de) 1987-11-23 1992-12-23 EASTMAN KODAK COMPANY (a New Jersey corporation) Küvette mit einer steifen wärmeleitenden Wand
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
ATE140880T1 (de) 1992-05-01 1996-08-15 Univ Pennsylvania Fluessigkeitsbehandlung in mikrofabrizierten analytischen vorrichtungen
WO2006044368A1 (en) * 2004-10-12 2006-04-27 Bioprocessors Corp. Microreactors incorporating interpenetrating and/or semi-interpenetrating polymers

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
WO2002043864A2 (en) * 2000-11-03 2002-06-06 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
EP1418243A2 (de) * 2002-10-31 2004-05-12 Hewlett-Packard Development Company, L.P. Mikrofluidsystem zur Analyse von Nukleinsäure

Also Published As

Publication number Publication date
EP1886727A1 (de) 2008-02-13
WO2008006617A2 (en) 2008-01-17
JP2009543548A (ja) 2009-12-10
EP2298449B1 (de) 2013-01-02
EP2298449A2 (de) 2011-03-23
EP2054155A2 (de) 2009-05-06
WO2008006617A3 (en) 2008-06-12
EP2054155B1 (de) 2012-10-17

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