EP2346608A2 - Pipette à course de piston électronique - Google Patents

Pipette à course de piston électronique

Info

Publication number
EP2346608A2
EP2346608A2 EP09804227A EP09804227A EP2346608A2 EP 2346608 A2 EP2346608 A2 EP 2346608A2 EP 09804227 A EP09804227 A EP 09804227A EP 09804227 A EP09804227 A EP 09804227A EP 2346608 A2 EP2346608 A2 EP 2346608A2
Authority
EP
European Patent Office
Prior art keywords
piston
electronic
pipette
kolbenhubpipette
control board
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP09804227A
Other languages
German (de)
English (en)
Inventor
Marcel Hoffmann
Hans-Jürgen Hoffmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AHN Biotechnology GmbH
Gilson SAS
Original Assignee
AHN Biotechnology GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AHN Biotechnology GmbH filed Critical AHN Biotechnology GmbH
Publication of EP2346608A2 publication Critical patent/EP2346608A2/fr
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0227—Details of motor drive means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0237—Details of electronic control, e.g. relating to user interface
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08—Ergonomic or safety aspects of handling devices
    • B01L2200/087—Ergonomic aspects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops

Definitions

  • the invention relates to a functional part of an electronic Kolbenhubpipette with an adapted to the manual Kolbenhubpipetten operating environment. Fields of application of the invention are analytical chemistry and medical diagnostics.
  • Piston lifting pipettes are volumetric instruments with reciprocating pistons.
  • a plastic or glass tip is placed on the piston stroke pipette. With the piston in the lower intake position, the tip is immersed in the liquid to be metered and dosed. The returning piston sucks the liquid. By depressing or displacing the piston between the volume-defining limits, the volume of liquid to be metered is expelled. With air bubble piston pipettes, there may be an additional air cushion that can be used to expel the last fluid volume.
  • the volume setting (piston position) in manual (mechanical) piston-stroke pipettes is usually performed stepwise in the microliter range or milliliter range via a counter or a micrometer screw.
  • the display is digitally mechanical.
  • the volume setting (piston adjustment) is carried out via buttons or small pushbuttons, electronically controlled and controlled. Buttons and pushbuttons are usually located laterally and / or diagonally on top of a corresponding control panel.
  • the display is via an electronic display.
  • the triggering weight for pipetting in automatic piston-stroke pipettes is much lower with approx. 50 grams and hardly burdening occupational health.
  • the piston guide is electronically controlled, making it much more precise and accurate.
  • Electronic piston-operated pipettes can do much more than just pipette.
  • Other laboratory applications such as dispensing, titration, multiple dispensing, sequential dispensing or mixing may be performed by software.
  • the task in designing and developing a new automatic (electronic) piston-stroke pipette was to develop a piston-stroke pipette that combines the advantages of a manual (mechanical) piston-displacement pipette with the advantages of the automatic (electronic) piston-driven pipette and minimizes the disadvantages of the automatic (electronic) piston-operated pipette .
  • the most important point was a self-explanatory, the well-known manual Kolbenhubpipette To create as close as possible control panel that allows the operator ergonomic cheap working in a familiar environment. It was intended to imitate the function of the control knob of the manual piston stroke pipette as closely as possible.
  • control knob for electronic Kolbenhubpipetten is such that it fits in design and execution in the overall picture of a Kolbenhubpipette and corresponds to the recognition value of a general Kolbenhubpipette.
  • the electronic Kolbenhubpipette is shown schematically in Figure 1.
  • the control knob 1 is made of thermoplastic material or metal, preferably made of polypropylene, ABS or POM.
  • the entire control knob consists of 1 or 2 parts:
  • the lower part as a cylindrical connection and / or detent to the electronics.
  • FIGS. 3-6 A schematic representation of the control knob 1 and the display housing 4 can be seen in Figure 2. More detailed illustrations have been made in FIGS. 3-6.
  • the upper part of the control knob is round or polygonal shaped, preferably 6-9 edged. About the top can be used to differentiate the volume of a different color Cover sleeve striped and / or jammed.
  • the diameter of the upper part is 18 to 22 mm, preferably 19 mm +/- 0.5 mm.
  • the thickness (thickness) of the upper part is 7 - 9 mm, preferably 8 mm +/- 0.5 mm.
  • the lower part of the control knob is cylindrically shaped with a diameter of 8-14 mm, preferably 11 mm +/- 0.5 mm.
  • the length of the lower part from the lower edge of the upper part to the lower edge of the lower part is 10-25 mm, preferably 14 mm +/- 0.5 mm).
  • the functional part according to the invention is such that
  • thermoplastics or metal preferably polypropylene, POM or ABS,
  • the functional part has an overall length of 125 to 150 mm, preferably 130 mm, See Figure 5 functional part.
  • housing display and electronic board a width of 38 to 48 mm, preferably 42.5 mm and has a length of 55 to 70 mm, preferably 58.3 mm and on this housing and the control knob is placed,
  • the functional part is ergonomically shaped so that the display and the electronic board are housed in the extended finger grip area of the functional part (clamping and / or screwing).
  • the display has a width between 22 and 30 mm, preferably 24.2 mm, and an overall height between 10 and 20 mm, preferably 16.6 mm.
  • the lower part of the finger grip area is shaped so that the index finger of the operator fits comfortably and securely in the finger recess and leads to an optimal placement of the functional part in the operator's hand and the finger grip with a radius R 10 to R 15, preferably R 12 is equipped .
  • the electronically controlled stepper motor (Linear Actuator) is fastened in the lower cylindrical or polygonal part, 4 edges or 9 edges, preferably round or 6 edges, of the functional part by clamping and / or screwing.
  • the necessary piston stroke of the pipette is carried out upwards or downwards, - That the battery or the battery of the small electric motor (Linear Actuators) is also placed in the lower cylindrical or polygonal part of the functional part.
  • the front part of the lower cylindrical or polygonal part of the functional part was shaped so that a slight to moderate curvature created by a removable handle cap, under which a commercially available, small round or square battery, preferably round, is placed to save space.
  • This battery and / or battery compartment has a length between 53 and 60 mm, preferably 54.58 mm and is covered by the handle cap,
  • this handle cap has an overall length of 90 to 120 mm, preferably 97 mm, and an outer radius of curvature between R 100 and R 110 and an inner radius of curvature between R 85 and R 90, preferably R 87.64.
  • the handle cap is equipped with ventilation channels for optimal handling.
  • the ventilation channels can be arranged both transversely and longitudinally.
  • the ventilation troughs integrated in the handle cap have a radius of R 1, 5 to R 1, 9, preferably R 1, 75.
  • the handle cap is removable and / or removable.
  • Pipette tip receiving cone, Ejektorhülse and Ejektorgestfite can be easily and easily inserted or screwed into the functional part of the invention, the coupling or mounting area down in the functional part between 35 and 40 mm long, preferably 37.4 mm.
  • the functional part has a bottom diameter between 30 and 40 mm, preferably 32.8 mm. See Fiqur 5 function part.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Human Computer Interaction (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Hydrology & Water Resources (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

L'invention concerne une partie fonctionnelle d'une pipette à course de piston électronique présentant un environnement de commande adapté aux pipettes à course de piston manuelles. La pipette à piston selon l'invention est constituée d'un cône de pipette (12) dans lequel se trouve un piston mobile (11) qui est relié rigide, par l'intermédiaire d'une tige de piston (10), à une transmission (7), pour pouvoir effectuer des mouvements vers le haut et vers le bas, la transmission étant entraînée par un moteur d'entraînement (5). La pipette selon l'invention est caractérisée en ce que la carte de circuits imprimés de commande (3) est constituée d'une partie supérieure servant de partie de commande (1) pour les mouvements de rotation et de poussée, et d'une tige servant de liaison cylindrique avec le système électronique. La carte de circuits imprimés de commande (3) et l'affichage sont intégrés dans la partie supérieure du boîtier d'affichage (2), et le moteur d'entraînement (5) et la batterie (rechargeable) sont intégrés dans la partie inférieure du boîtier de pipette (9). Les domaines d'application de l'invention sont la chimie analytique et le diagnostique médical.
EP09804227A 2008-09-23 2009-09-22 Pipette à course de piston électronique Ceased EP2346608A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008048620A DE102008048620B4 (de) 2008-09-23 2008-09-23 Elektronische Kolbenhubpipette
PCT/DE2009/001310 WO2010034290A2 (fr) 2008-09-23 2009-09-22 Pipette à course de piston électronique

Publications (1)

Publication Number Publication Date
EP2346608A2 true EP2346608A2 (fr) 2011-07-27

Family

ID=41693866

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09804227A Ceased EP2346608A2 (fr) 2008-09-23 2009-09-22 Pipette à course de piston électronique

Country Status (8)

Country Link
US (1) US20110214518A1 (fr)
EP (1) EP2346608A2 (fr)
JP (1) JP2012503182A (fr)
KR (1) KR20110069825A (fr)
CN (1) CN102378649A (fr)
CA (1) CA2737990A1 (fr)
DE (1) DE102008048620B4 (fr)
WO (1) WO2010034290A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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US8871157B2 (en) * 2011-05-17 2014-10-28 Rainin Instrument, Llc Electronic pipette with two-axis controller
ES2713392T3 (es) * 2012-02-13 2019-05-21 Thermo Fisher Scientific Oy Pipeta electrónica
FI125309B (fi) 2012-03-30 2015-08-31 Sartorius Biohit Liquid Handling Oy Pipetin säätöpyörä
CN104289260A (zh) * 2014-08-29 2015-01-21 浙江海洋学院 一种移液管配套装置
JP6354691B2 (ja) * 2015-07-24 2018-07-11 株式会社安川電機 処理システム、制御方法、動作指令生成装置及びコンピュータプログラム
JP6737554B2 (ja) 2016-09-27 2020-08-12 株式会社エー・アンド・デイ ピペットチップ装着用アダプタ
DE102016121816A1 (de) 2016-11-14 2018-05-17 Ika-Werke Gmbh & Co. Kg Fluidabgabeeinheit und Handdosiervorrichtung mit wenigstens einer Fluidabgabeeinheit
CN106694070B (zh) * 2017-01-31 2019-04-26 佛山市顺德区罗恩科学仪器有限公司 移液器不等量分液操作方法
CN106799267B (zh) * 2017-01-31 2019-05-07 佛山市顺德区罗恩科学仪器有限公司 移液器等量分液操作方法
CN107597222B (zh) * 2017-09-08 2019-09-27 莫纳（苏州）生物科技有限公司 电动手工加样器
FR3073755B1 (fr) * 2017-11-20 2019-12-20 Gilson Sas Accessoire fonctionnalise pour pipette mecanique de prelevement

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See references of WO2010034290A2 *

Also Published As

Publication number Publication date
JP2012503182A (ja) 2012-02-02
DE102008048620B4 (de) 2011-09-15
KR20110069825A (ko) 2011-06-23
CN102378649A (zh) 2012-03-14
WO2010034290A3 (fr) 2010-06-17
US20110214518A1 (en) 2011-09-08
DE102008048620A1 (de) 2010-03-25
WO2010034290A2 (fr) 2010-04-01
CA2737990A1 (fr) 2010-04-01

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