EP2384201A4 - Polypeptide zur induktion einer schützenden immunantwort gegen staphylococcus aureus - Google Patents

Polypeptide zur induktion einer schützenden immunantwort gegen staphylococcus aureus

Info

Publication number
EP2384201A4
EP2384201A4 EP09829714A EP09829714A EP2384201A4 EP 2384201 A4 EP2384201 A4 EP 2384201A4 EP 09829714 A EP09829714 A EP 09829714A EP 09829714 A EP09829714 A EP 09829714A EP 2384201 A4 EP2384201 A4 EP 2384201A4
Authority
EP
European Patent Office
Prior art keywords
staphylococcus
polypeptides
dog
inducing
immune response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09829714A
Other languages
English (en)
French (fr)
Other versions
EP2384201A1 (de
Inventor
Tessie B Mcneely
Leslie D Cope
Mark A Miller
Loren D Schultz
Xinmin Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp & Dohme LLC
Original Assignee
Merck Sharp and Dohme Ltd
Merck Sharp & Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd, Merck Sharp & Dohme LLC filed Critical Merck Sharp and Dohme Ltd
Publication of EP2384201A1 publication Critical patent/EP2384201A1/de
Publication of EP2384201A4 publication Critical patent/EP2384201A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP09829714A 2008-11-26 2009-11-18 Polypeptide zur induktion einer schützenden immunantwort gegen staphylococcus aureus Withdrawn EP2384201A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20027308P 2008-11-26 2008-11-26
PCT/US2009/064925 WO2010062814A1 (en) 2008-11-26 2009-11-18 Polypeptides for inducing a protective immune response against staphylococcus aureus

Publications (2)

Publication Number Publication Date
EP2384201A1 EP2384201A1 (de) 2011-11-09
EP2384201A4 true EP2384201A4 (de) 2013-01-09

Family

ID=42226003

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09829714A Withdrawn EP2384201A4 (de) 2008-11-26 2009-11-18 Polypeptide zur induktion einer schützenden immunantwort gegen staphylococcus aureus

Country Status (9)

Country Link
US (1) US20110229509A1 (de)
EP (1) EP2384201A4 (de)
JP (1) JP2012509664A (de)
CN (1) CN102292105A (de)
AU (1) AU2009319946A1 (de)
CA (1) CA2744323A1 (de)
IL (1) IL212665A0 (de)
MX (1) MX2011005578A (de)
WO (1) WO2010062814A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2593133A4 (de) 2010-07-13 2014-11-26 Merck Sharp & Dohme Staphylococcus aureus-oberflächenprotein sa1789 und darauf basierender schutzimpfstoff
WO2012065034A1 (en) 2010-11-12 2012-05-18 Merck Sharp & Dohme Corp. Enolase peptide conjugate vaccines against staphylococcus aureus
WO2013066731A2 (en) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Protective vaccine based on staphylococcus aureus sa2451 protein
EP2872173A4 (de) 2012-07-10 2016-03-23 Merck Sharp & Dohme Schutzimpfstoff auf grundlage des staphylococcus-aureus-proteins sa2493
EP3077820B1 (de) * 2013-12-03 2025-02-26 Evaxion Biotech A/S Proteine und nukleinsäuren zur verwendung für impfstoffe gegen staphylococcus aureus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000050433A2 (en) * 1999-02-26 2000-08-31 Smithkline Beecham Corporation Staphylococcus aureus q13 polynucleotides, polypeptides and methods of use
WO2002094868A2 (en) * 2001-03-27 2002-11-28 Chiron Srl. Staphylococcus aureus proteins and nucleic acids

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5505947A (en) 1994-05-27 1996-04-09 The University Of North Carolina At Chapel Hill Attenuating mutations in Venezuelan Equine Encephalitis virus
US6737248B2 (en) 1996-01-05 2004-05-18 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
US6156588A (en) 1998-06-23 2000-12-05 Vlsi Technology, Inc. Method of forming anti-fuse structure
GB0014907D0 (en) 2000-06-20 2000-08-09 Univ Sheffield Antigenic polypeptides
AT410798B (de) 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
JP4475561B2 (ja) 2001-10-11 2010-06-09 メルク・シャープ・エンド・ドーム・コーポレイション Ｃ型肝炎ウイルスワクチン
WO2005009378A2 (en) * 2003-07-24 2005-02-03 Merck & Co., Inc. Polypeptides for inducing a protective immune response against staphylococcus aureus
JP4814800B2 (ja) 2004-01-23 2011-11-16 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー チンパンジーアデノウイルスワクチン担体
CN1918176A (zh) * 2004-02-18 2007-02-21 默克公司 用于诱导针对金黄色葡萄球菌的保护性免疫反应的多肽
AU2005247435A1 (en) * 2004-05-25 2005-12-08 Merck & Co., Inc. Polypeptides for inducing a protective immune response against Staphylococcus aureus
US20070264278A1 (en) * 2004-09-17 2007-11-15 Anderson Annaliesa S Polypeptides for Inducing a Protective Immune Response Against Staphylococcus Aureus
WO2006078680A2 (en) * 2005-01-21 2006-07-27 Merck & Co., Inc. Polypeptides for inducing a protective immune response against staphylococcus aureus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000050433A2 (en) * 1999-02-26 2000-08-31 Smithkline Beecham Corporation Staphylococcus aureus q13 polynucleotides, polypeptides and methods of use
WO2002094868A2 (en) * 2001-03-27 2002-11-28 Chiron Srl. Staphylococcus aureus proteins and nucleic acids

Also Published As

Publication number Publication date
WO2010062814A1 (en) 2010-06-03
AU2009319946A1 (en) 2010-06-03
JP2012509664A (ja) 2012-04-26
US20110229509A1 (en) 2011-09-22
MX2011005578A (es) 2011-06-30
IL212665A0 (en) 2011-07-31
EP2384201A1 (de) 2011-11-09
CA2744323A1 (en) 2010-06-03
CN102292105A (zh) 2011-12-21

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Legal Events

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Effective date: 20110627

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DAX Request for extension of the european patent (deleted)
RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: MERCK SHARP & DOHME CORP.

A4 Supplementary search report drawn up and despatched

Effective date: 20121207

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 14/31 20060101ALI20121203BHEP

Ipc: A61P 31/04 20060101ALI20121203BHEP

Ipc: A61K 39/085 20060101AFI20121203BHEP

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Effective date: 20150723