EP2452149B1 - Échangeur de chaleur à plaques - Google Patents

Échangeur de chaleur à plaques Download PDF

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Publication number
EP2452149B1
EP2452149B1 EP10724312.3A EP10724312A EP2452149B1 EP 2452149 B1 EP2452149 B1 EP 2452149B1 EP 10724312 A EP10724312 A EP 10724312A EP 2452149 B1 EP2452149 B1 EP 2452149B1
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EP
European Patent Office
Prior art keywords
plates
plate
fluid
heat exchanger
plate heat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP10724312.3A
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German (de)
English (en)
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EP2452149A2 (fr
Inventor
Oscar-Werner Reif
Jürgen VAN DEN BOOGAARD
Stefan Weisshaar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Stedim Biotech GmbH
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Sartorius Stedim Biotech GmbH
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Publication of EP2452149A2 publication Critical patent/EP2452149A2/fr
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Publication of EP2452149B1 publication Critical patent/EP2452149B1/fr
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Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28DHEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
    • F28D9/00Heat-exchange apparatus having stationary plate-like or laminated conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall
    • F28D9/0031Heat-exchange apparatus having stationary plate-like or laminated conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall the conduits for one heat-exchange medium being formed by paired plates touching each other
    • F28D9/0043Heat-exchange apparatus having stationary plate-like or laminated conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall the conduits for one heat-exchange medium being formed by paired plates touching each other the plates having openings therein for circulation of at least one heat-exchange medium from one conduit to another
    • F28D9/005Heat-exchange apparatus having stationary plate-like or laminated conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall the conduits for one heat-exchange medium being formed by paired plates touching each other the plates having openings therein for circulation of at least one heat-exchange medium from one conduit to another the plates having openings therein for both heat-exchange media
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28FDETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F17/00Removing ice or water from heat-exchange apparatus
    • F28F17/005Means for draining condensates from heat exchangers, e.g. from evaporators
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28FDETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F21/00Constructions of heat-exchange apparatus characterised by the selection of particular materials
    • F28F21/06Constructions of heat-exchange apparatus characterised by the selection of particular materials of plastics material
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28FDETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F2275/00Fastening; Joining
    • F28F2275/02Fastening; Joining by using bonding materials; by embedding elements in particular materials
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28FDETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F2275/00Fastening; Joining
    • F28F2275/06Fastening; Joining by welding
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28FDETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F2280/00Mounting arrangements; Arrangements for facilitating assembling or disassembling of heat exchanger parts
    • F28F2280/06Adapter frames, e.g. for mounting heat exchanger cores on other structure and for allowing fluidic connections

Definitions

  • the invention relates to a plate heat exchanger having a plurality of flow channels having plates, wherein a first plate having a front side with at least one flow channel for a first fluid and a second plate has a front with at least one flow channel for a second fluid, and wherein the plates have through holes, via which the flow passages for the same fluid are respectively connected to each other, wherein a front plate, which is upstream of the front of the first plate, connections for the first fluid and for the second fluid, and wherein an end plate forms the conclusion of the juxtaposed plates.
  • Heat exchangers are commonly used. Heat is transferred from the warmer medium to the colder medium. The media are separated from each other. There is a need for Heat exchangers that are very inexpensive in terms of material and manufacturing.
  • a plate heat exchanger with a plurality of flow channels plates is known.
  • a first plate has at least one flow channel for a first fluid and a second plate has at least one flow channel for a second fluid.
  • the plates have through openings through which the flow channels for the same fluid are connected to each other.
  • a plate heat exchanger consisting of several with the interposition of seals using pressure plates into a plate package joinable plastic plates, between which adjacent flow gaps are formed, which are successively flowed through plate flow openings alternately by a heat-emitting and heat-absorbing medium, known as Heat transfer plates are used, which are formed as flat plates, between which so-called turbulence plates are arranged, the surfaces of which have turbulence profiles on one or both sides in order to generate flow turbulences in the flow gap or flow channel.
  • Heat transfer plates which are formed as flat plates, between which so-called turbulence plates are arranged, the surfaces of which have turbulence profiles on one or both sides in order to generate flow turbulences in the flow gap or flow channel.
  • EP 0 038 454 A2 is a plate heat exchanger consisting of a plurality of extruded single sheets of polycarbonate known.
  • a plate heat exchanger having a plurality of flow channel forming plates is known.
  • a first plate 4a, 4c in this case has a meandering opening 6, which forms a flow channel for a first fluid with two adjacent flat plates 2a, 2b.
  • a corresponding second plate 4b, 4d has a meandering aperture 6 arranged in mirror image, which with two adjacent flat plates 2b, 2c and 2d, 2e has a second flow channel extending parallel to the first flow channel for a second fluid.
  • the flow channels for the same fluid are connected to each other.
  • a plate heat exchanger which is flowed through by a first and a second fluid, wherein between a front plate and a cover plate, a plurality of stacked plates is arranged, which are partially spaced apart and in contact, so that between them in a heat transfer region flow channels are formed , which are connected to each other for the same fluid.
  • the spacing of the plates is effected by formations which are formed by partially arranged knobs and / or beads.
  • a separate drain of condensate is not possible.
  • a plate heat exchanger which can be traversed by two separate media, with stacked plates, which are partially spaced and in regions in contact, so that between each adjacent plates flow channels are formed.
  • the plates are spaced apart by formations of the plates, wherein over the circumference of the plates successive areas having openings or through openings (via which the flow channels for the same fluid are each connected to each other), alternately formed in the opposite direction from the plane of the plates are.
  • a separate outflow of condensate is not possible.
  • a plate heat exchanger in which first plates and second plates are stacked, wherein at least one plate surface has a rectilinearly parallel profiling, so that between adjacent plate elements flow spaces of a plurality of rectilinear parallel flow channels are formed, which alternately via inlet and outlet channels with a first and a second fluid can be charged.
  • a separate drain of condensate nor a plenum for receiving condensate is known.
  • a plate heat exchanger having a plurality of parallel, spaced plates between which flow channels for first and second fluids are formed. Another disadvantage here is that no separate outflow of condensate from a collecting space for receiving the condensate is arranged.
  • WO2008 / 024066 A1 From the WO2008 / 024066 A1 is also known a plate heat exchanger with a plurality of plates, between which formations for forming flow channels are arranged. Although this plate exchanger in the vertical direction down an additional drain for removing the first liquid in the first channel, which is not connected to a separate collection space. A note on the discharge of condensate is also not refer to this citation.
  • a plate heat exchanger with a plurality of flow channels plates is known.
  • a first plate has a front side with at least one flow channel for a first fluid (heated steam) and a second plate has a front side with at least one flow channel for a second fluid (raw liquid).
  • the plates have through openings, via which the flow channels for the same fluid are respectively connected to one another.
  • the front of the first plate is preceded by a front plate having ports for the first fluid and ports for the second fluid.
  • the conclusion The juxtaposed plates is formed by an end plate.
  • a disadvantage of the known plate heat exchanger that the plates are relatively expensive sealed against each other via seals. Another disadvantage is that no collecting space is provided for the second fluid, can be removed via the condensate separated from the second fluid.
  • Object of the present invention is therefore to provide a plate heat exchanger available, which is simple and inexpensive in terms of material and production and which makes it possible, for example, due to a cooling of gas resulting condensate.
  • the object is achieved in conjunction with the preamble of claim 1, characterized in that the plates and connections are made of plastic, that the plates are glued or welded tightly together, and that the flow channel for the second fluid in the lower region in the vertical direction a collecting space has, which serves to receive condensate, which is discharged via a arranged on the front plate condensate connection that the communicating with the collecting space through holes for the second fluid of the plates are elongated and with passage openings of the plates correspond, and that these passage openings in their vertically lower portion with the condensate connection and in its vertical upper portion with the connection to the flow channel of the second plates in connection.
  • the plate heat exchanger according to the invention is simple in construction and can be produced inexpensively by simple production of its plastic plates, for example by injection molding of the plates. By gluing or by connecting the plates in a plastic welding process can be dispensed with seals.
  • the plate heat exchangers can be manufactured so cheaply that they can be used as a disposable heat exchanger. This can be dispensed with a costly cleaning or disassembly. Due to their structure, the plate heat exchangers according to the invention are suitable for applications in the pharmaceutical, biotechnology and food industries.
  • communicating with the collecting space through holes of the plates are elongated and formed in its lower in the vertical direction with the condensate connection and in its upper vertical direction Area are connected to the connection to the flow channel of the second plate, can advantageously be discharged via the same through-openings both the second fluid and its condensate via separate ports.
  • the plates are flat on their backs facing away from the front sides. This has the advantage that the plates can be strung together in any order.
  • the plates on their backs facing away from the front sides of the flow channels of the adjacent front sides corresponding mirror-symmetrical flow channels.
  • the flow channels of the plates each have flow straighteners.
  • the flow straighteners are designed as barriers or partitions arranged in the flow channels.
  • the dividing walls of flow channels for the first fluid and of flow channels for the second fluid are preferably arranged perpendicular to one another. This contributes to a better heat exchange.
  • the plates and connections are formed from a sterilizable plastic. This makes it possible to deliver the plate heat exchangers sterile packed.
  • the plate heat exchangers are sterilizable by irradiation with gamma or beta rays become. It is also possible to sterilize the plate heat exchangers by autoclaving with superheated steam.
  • the plate heat exchanger is connected to a bioreactor, which is preferably also sterilizable.
  • connection for the inlet of the first fluid can be connected to an exhaust pipe of the bioreactor and the connection for the outlet of the first fluid can be connected to an inlet of a sterile filter, while the connections for the second fluid are connected to a cooling circuit can be.
  • Liquid vapors taken up during the gassing of the bioreactor are condensed and the condensate is returned to the bioreactor, and the dried waste gas can now be discharged via a sterile filter without being blocked by condensed liquid.
  • the inlet for the first fluid is connected to a medium supply line for supplying the medium and the exit point for the first fluid is connected to an inflow port of the bioreactor the second fluid is connected to a temperature control circuit.
  • a plate heat exchanger 1 essentially consists of a plurality of first plates 40 and second plates 50 with flow channels 4, 5, a front plate 6 and an end plate 7.
  • the first plate 40 has a front side 2 and a back side 41. In the vertical direction, the first plate 40 in its lower left and upper left corners through openings 8, 9 for a first fluid.
  • a flat depression is arranged, which forms the flow channel 4 and extends into the passage openings 8, 9.
  • the flow channel 4 has in the horizontal direction from the side walls forth flow barriers 10, 11 of a flow director 12, which overlap in the horizontal direction and thus form a meandering flow channel 4.
  • the back 41 is flat, that is without a flow channel formed.
  • the first plate 40 in the vertical direction at the top right and bottom right through openings 13, 14, respectively.
  • the second plate 50 has on its front side 3 a flat depression which forms the flow channel 5 and extends into the right through openings 17, 18.
  • the flow channel 5 has flow barriers 15 running in the vertical direction, which form a flow straightener 16.
  • the plate 50 outside the flow channel 5 through holes 19, 20, which with the Through holes 8, 9 of the plate 40 correspond.
  • the passage openings 17, 18 of the plate 50 correspond to the passage openings 13, 14 of the plate 40.
  • the plate 50 has a rear side 51 facing away from its front side 3, which is flat and thus has no flow channel.
  • the plate heat exchanger 1 has on its front side the front plate 6 with its connections 21, 22 for the first fluid and connections 23, 24 for the second fluid.
  • the connection 21 communicates with the passage openings 8, 19 and serves to supply the first fluid, which is discharged via the connection 22, which is in communication with the passage openings 9, 20.
  • the front panel can be optional on its in FIG. 1 not shown back have a flow channel 4 '.
  • the port 23 communicates with the through holes 14 and 18 and serves to supply the second fluid, while the port 24 communicates with the through holes 13 and 17 and is used to discharge the second fluid.
  • the plate heat exchanger 1 is closed at its end facing away from the front panel 6 by the end plate 7.
  • the end plate 7 may have a flow channel 4 in this embodiment and has no through holes in this embodiment.
  • this is identical to the front plate 6 and is arranged in the plate heat exchanger 1 mirror-symmetrical to the front panel 6.
  • the front of the end plate can be like in the FIG. 1 However, it may also be flat and thus be formed without a flow channel 4 and may furthermore have passage openings, not shown, which correspond to the passage openings of the plates 40 and 50.
  • the front plate 6 and the end plate 7 are each provided with through holes to increase the cross section of the fluid supply, without having to change the sizing of the terminals 21, 22, 23 and 24. In this way, the pressure loss during inflow and outflow of the fluids into and out of the heat exchanger 1 can be minimized in a particularly advantageous manner.
  • the plates 40 and 50 are at their backs, as explained above, each flat, while the back of the front panel 6 and / or the front of the end plate 7 may be formed flat or alternatively may have a flow channel 4, 4 '.
  • the plates 40, 50, 6 and 7 are each glued to their adjacent plate.
  • FIG. 2 shows a plate 40 'and 50' with a flow channel 4 'on its front side 2' for a first fluid, which is formed for example as a cooling medium.
  • the first plate 40 'and 50' in their lower left and upper left corners through openings 8 ', 9' for the first fluid.
  • the flow channel 4 ' is arranged, which is in communication with the passage openings 8', 9 '. Outside the flow channel 4 ', the side 2' in the vertical direction at the top and bottom right each of the through holes 13 ', 14'.
  • the back 41 'of the first plate 40' (see FIG. 3 ) has a flow channel 5 'for a second fluid.
  • the plate 40 'and the plate 50' are exactly identical. Analogous to the in FIG. 1 As shown, the plates 40 'and 50' can be assembled into a plate heat exchanger, with the plates 50 'being mounted facing the identical plates 40', turned through 180 °. Unlike the embodiment according to FIG. 1 in which the back faces of the plates 40 and 50 are each plane, this assembly results in a plate heat exchanger 1, in which the front and the back of the composite plates 40 'and 50' each have a flow channel 4 'and 5'.
  • the flow channel 5 'on a collecting space 25 which serves to receive condensate, which via a condensate connection 26 which on the front plate 6' (see FIG. 4 ) is arranged, is discharged.
  • the passage openings 13 'and 14' for the second fluid of the plate 50 ' are elongated and correspond to passage openings 13', 14 'of the plate 40' (see FIG. 2 ).
  • the back 51 'of the plate 50' (see FIG. 3 ) has a flow channel 4 'of another identical plate 40' or the flow channel 4 'of an end plate 7' corresponding flow channel for a first fluid.
  • the plate heat exchanger 1, 1 ' according to the embodiments of the FIGS. 1 to 6 are made of polycarbonate (PC). They are readily gamma-irradiated and are suitable for any sterile application in the temperature range up to 110 ° C, for a short time even up to 125 C. Thus, the heat plate exchanger 1, 1 'can also be sterilized with superheated steam.
  • PC polycarbonate
  • the plate heat exchanger 1 ' is connected to a bioreactor 27' and is used as an exhaust gas cooler.
  • the exhaust gas is introduced from the head space 28 of the bioreactor 27 'via an exhaust pipe 29 connected to the port 23' of the plate heat exchanger 1 'at the top of the plate heat exchanger 1'.
  • the gas flow over the flow channel 5' over the individual front sides 3 'of the plates 50' is divided.
  • the gas stream is cooled when flowing down the plate wall and discharged through the port 24 'and further discharged through a sterile filter 30 to the environment.
  • the humidity of the exhaust gas is lowered, wherein the liquid medium taken in the bioreactor condensed, discharged via the condensate connection 26 and the bioreactor 27' is fed via a peristaltic pump.
  • cooling medium is introduced from the primary cooler 33 from below via the connection 21 'into the plate heat exchanger 1'. From the through holes 8 ', the cooling medium is introduced into the individual flow channels 4' and absorbs the heat from the plates 40 'and 50'. The cooling medium heats up. The cooling medium is collected in the passage opening 9 'and conveyed back into the primary cooler 33 via the connection 22'. The cooling medium is circulated.
  • the plate heat exchanger 1 is connected to the bioreactor 27 via a feed line 31.
  • the plate heat exchanger 1 is used to pre-heat the bioreactor 27 to be supplied medium.
  • the medium to be heated is introduced from a reservoir, not shown, in the plate heat exchanger 1 from above via the terminal 23.
  • the material flow over the resulting from the through holes 14 and 18 flow distributor in the individual channels 5 distributed.
  • the media stream is warmed up when flowing down the plate wall.
  • the media streams are merged and directed to the output or port 24. From port 24, the preheated medium is fed into the bioreactor 27.
  • heating medium is introduced from below by a thermostat 32 via the connection 21 into the plate heat exchanger 1.
  • the heating medium is introduced into the individual channels 4 and gives the heat to the plates 40 and 50 from.
  • the heating medium is conveyed from the outlet or from the connection 22 back into the thermostat 32.
  • the heating medium is circulated.

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)

Claims (15)

  1. Échangeur de chaleur (1, 1') à plaques comportant une pluralité de plaques (40, 40', 50, 50') présentant des canaux d'écoulement (4, 4', 5, 5'), une première plaque (40, 40') comprenant un côté avant (2, 2') présentant au moins un canal d'écoulement (4, 4') pour un premier fluide et une deuxième plaque (50, 50') comprenant un côté avant (3, 3') présentant au moins un canal d'écoulement (5, 5') pour un deuxième fluide,
    et les plaques (40, 40', 50, 50') présentant des ouvertures traversantes (8, 8', 9, 9', 13, 13', 14, 14', 19, 20) reliant mutuellement les canaux d'écoulement (4, 4', 5, 5') pour le même fluide,
    une plaque frontale (6, 6'), montée en amont du côté avant (2, 2') de la première plaque (40, 40'), présentant des raccords (21, 21', 22, 22', 23, 23', 24, 24') pour le premier et le deuxième fluide,
    et une plaque de terminaison (7, 7') formant la terminaison des plaques montées en série (40, 40', 50, 50', 6, 6'),
    le canal d'écoulement (5') pour le deuxième fluide présentant, dans la région inférieure en direction verticale, un collecteur (25) qui sert à recevoir du condensat qui peut être évacué par l'intermédiaire d'un raccord de condensat (26),
    caractérisé en ce que
    les plaques (40, 40', 50, 50', 6, 6', 7, 7') et les raccords (21, 21', 22, 22', 23, 23', 24, 24') sont réalisés en plastique,
    en ce que les plaques (40, 40', 50, 50', 6, 6', 7, 7') sont collées ou soudées étroitement les unes aux autres,
    en ce que les ouvertures traversantes (13', 14') des plaques (50') pour le deuxième fluide, ouvertures qui sont reliées à l'espace collecteur (25), sont réalisées oblongues et sont en correspondance avec des ouvertures traversantes (13', 14') des plaques (40'),
    et en ce que ces ouvertures traversantes (13', 14') sont reliées au raccord de condensat (26) dans leur région inférieure en direction verticale, et au branchement (24') sur le canal d'écoulement (5') des deuxièmes plaques (50') dans leur région supérieure en direction verticale.
  2. Échangeur de chaleur à plaques selon la revendication 1, caractérisé en ce que la plaque de terminaison (7, 7') possède des ouvertures traversantes qui sont en correspondance avec les ouvertures traversantes (8, 8', 9, 9', 13, 13', 14, 14', 19, 20) des plaques (40, 40', 50, 50').
  3. Échangeur de chaleur à plaques selon l'une des revendications 1 ou 2, caractérisé en ce que le côté arrière de la plaque frontale (6, 6') présente un canal d'écoulement (4, 4').
  4. Échangeur de chaleur à plaques selon l'une des revendications 1 à 3, caractérisé en ce que le côté avant de la plaque de terminaison (7, 7') présente un canal d'écoulement (4, 4').
  5. Échangeur de chaleur à plaques selon l'une des revendications 1 à 2 ou 4, caractérisé en ce que le côté arrière (61, 61') de la plaque frontale (6, 6') est plan.
  6. Échangeur de chaleur à plaques selon l'une des revendications 1 à 3 ou 5, caractérisé en ce que le côté avant de la plaque de terminaison (7, 7') est plan.
  7. Échangeur de chaleur à plaques selon l'une des revendications 1 à 6, caractérisé en ce que les plaques (40, 50) sont réalisées planes sur leurs côtés arrière (41, 51) opposés aux côtés avant (2, 3).
  8. Échangeur de chaleur à plaques selon l'une des revendications 1 à 6, caractérisé en ce que les plaques (40', 50', 6', 7') présentent, sur leurs côtés arrière (41', 51', 61') opposés aux côtés avant (2', 3'), des canaux d'écoulement symétriques (4', 5') correspondant aux canaux d'écoulement (4', 5') des côtés avant voisins (2', 3').
  9. Échangeur de chaleur à plaques selon la revendication 8, caractérisé en ce que les premières plaques (40') et les deuxièmes plaques (50') sont réalisées structurellement identiques,
    et en ce que les deuxièmes plaques (50') sont montées tournées d'une manière correspondant à 180° par rapport aux premières plaques (40').
  10. Échangeur de chaleur à plaques selon l'une des revendications 1 à 9, caractérisé en ce que les canaux d'écoulement (4, 4', 5, 5') présentent un guide d'écoulement (12, 16).
  11. Échangeur de chaleur à plaques selon l'une des revendications 1 à 10, caractérisé en ce que les plaques (40, 40', 50, 50', 6, 6', 7, 7') et les raccords (21, 21', 22, 22', 23, 23', 24, 24', 26) sont réalisés en un plastique stérilisable.
  12. Échangeur de chaleur à plaques selon l'une des revendications 1 à 11, caractérisé en ce que les plaques (40, 40', 50, 50', 6, 6', 7, 7') et les raccords (21, 21', 22, 22', 23, 23', 24, 24', 26) peuvent être irradiés par des rayons gamma et/ou bêta, et/ou autoclavées à la vapeur surchauffée.
  13. Ensemble constitué d'un bioréacteur (27, 27') et d'un échangeur de chaleur à plaques selon l'une des revendications 1 à 12, caractérisé en ce que l'échangeur de chaleur (1, 1') à plaques est relié au bioréacteur (27, 27').
  14. Ensemble selon la revendication 13, caractérisé en ce que, afin de refroidir un gaz à évacuer du bioréacteur (27'), le raccord (23') pour l'entrée du deuxième fluide est relié à une conduite d'effluents gazeux (29) du bioréacteur (27') et le raccord (24') pour la sortie du deuxième fluide est relié à une entrée d'un filtre stérile (30),
    et en ce que les raccords (21', 22') pour le premier fluide sont reliés à un circuit de refroidissement.
  15. Ensemble selon la revendication 13, caractérisé en ce que, afin de préchauffer un agent à apporter au bioréacteur (27), le raccord (23) pour l'entrée du deuxième fluide est relié à une conduite d'apport d'agent (31) destinée à apporter l'agent et le raccord (24) pour la sortie du deuxième fluide est relié à un raccord de flux entrant du bioréacteur (27),
    et en ce que les raccords (21, 22) pour le premier fluide sont reliés à un circuit de thermorégulation.
EP10724312.3A 2009-07-08 2010-06-10 Échangeur de chaleur à plaques Active EP2452149B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009032370A DE102009032370A1 (de) 2009-07-08 2009-07-08 Plattenwärmetauscher
PCT/EP2010/003490 WO2011003496A2 (fr) 2009-07-08 2010-06-10 Échangeur de chaleur à plaques

Publications (2)

Publication Number Publication Date
EP2452149A2 EP2452149A2 (fr) 2012-05-16
EP2452149B1 true EP2452149B1 (fr) 2019-03-06

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Application Number Title Priority Date Filing Date
EP10724312.3A Active EP2452149B1 (fr) 2009-07-08 2010-06-10 Échangeur de chaleur à plaques

Country Status (5)

Country Link
US (1) US9228784B2 (fr)
EP (1) EP2452149B1 (fr)
JP (1) JP5892930B2 (fr)
DE (2) DE102009032370A1 (fr)
WO (1) WO2011003496A2 (fr)

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US8455242B2 (en) 2010-02-22 2013-06-04 Hyclone Laboratories, Inc. Mixing system with condenser
DE102011001818A1 (de) 2011-04-05 2012-10-11 Michael Rehberg Plattenwärmeübertrager aus Kunststoff
WO2013053779A1 (fr) 2011-10-10 2013-04-18 DASGIP Information and Process Technology GmbH Appareil biotechnologique comprenant un bioréacteur, régulateur de température de gaz d'échappement pour un bioréacteur et procédé de traitement de flux de gaz d'échappement dans un appareil biotechnologique
EP2614764A3 (fr) * 2012-01-12 2017-03-29 Winterhalter Gastronom Gmbh Echangeur de chaleur d'eaux usées pour lave-vaisselle ainsi que lave-vaisselle
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WO2011003496A3 (fr) 2011-03-03
DE102009032370A1 (de) 2011-01-13
JP5892930B2 (ja) 2016-03-23
EP2452149A2 (fr) 2012-05-16
DE202010007615U1 (de) 2010-08-26
JP2012532307A (ja) 2012-12-13
WO2011003496A2 (fr) 2011-01-13
US9228784B2 (en) 2016-01-05
US20120103579A1 (en) 2012-05-03

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