EP2515930A4 - Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells - Google Patents

Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells

Info

Publication number
EP2515930A4
EP2515930A4 EP10838658.2A EP10838658A EP2515930A4 EP 2515930 A4 EP2515930 A4 EP 2515930A4 EP 10838658 A EP10838658 A EP 10838658A EP 2515930 A4 EP2515930 A4 EP 2515930A4
Authority
EP
European Patent Office
Prior art keywords
methods
tumor cells
leukocyte cell
compositions related
met phosphorylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10838658.2A
Other languages
German (de)
French (fr)
Other versions
EP2515930A1 (en
Inventor
Min-Liang Kuo
Yu-Ling Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TTY Biopharm Co Ltd
Original Assignee
TTY Biopharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TTY Biopharm Co Ltd filed Critical TTY Biopharm Co Ltd
Publication of EP2515930A1 publication Critical patent/EP2515930A1/en
Publication of EP2515930A4 publication Critical patent/EP2515930A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP10838658.2A 2009-12-21 2010-12-20 Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells Withdrawn EP2515930A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28862709P 2009-12-21 2009-12-21
PCT/CN2010/079993 WO2011076095A1 (en) 2009-12-21 2010-12-20 Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells

Publications (2)

Publication Number Publication Date
EP2515930A1 EP2515930A1 (en) 2012-10-31
EP2515930A4 true EP2515930A4 (en) 2013-04-10

Family

ID=44194951

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10838658.2A Withdrawn EP2515930A4 (en) 2009-12-21 2010-12-20 Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells

Country Status (4)

Country Link
EP (1) EP2515930A4 (en)
CN (1) CN102802658A (en)
TW (1) TW201200151A (en)
WO (1) WO2011076095A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102559739B (en) * 2012-01-20 2014-06-25 宁波大学 Expressing and purifying method of recombinant human-derived LECT2 protein in Pichia pastoris
WO2013158485A1 (en) 2012-04-18 2013-10-24 Massachusetts Institute Of Technology Menainv and cancer invasion and metastasis
CA2925107A1 (en) 2013-10-02 2015-04-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the lect2 gene
US10745702B2 (en) 2015-04-08 2020-08-18 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the LECT2 gene

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2347761A1 (en) * 2008-09-22 2011-07-27 TTY Biopharm Company Limited A composition with inhibition activity on pathological angiogenesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5645829A (en) 1993-06-18 1997-07-08 Beth Israel Hospital Association Mesothelial cell gene therapy
ES2325344B1 (en) * 2004-11-02 2010-06-09 Univ Madrid Autonoma MULTIFUNCTIONAL AND MULTIVALENT ANGIOGENESIS INHIBITORS.
CN1785426A (en) * 2005-10-27 2006-06-14 南京大学 Method of inhibiting neonate tumour blood vessel
EP2056812A1 (en) * 2006-08-31 2009-05-13 Abraxis BioScience, LLC Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2347761A1 (en) * 2008-09-22 2011-07-27 TTY Biopharm Company Limited A composition with inhibition activity on pathological angiogenesis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
See also references of WO2011076095A1 *
UCHIDA T ET AL: "Expression pattern of a newly recognized protein, LECT2, in hepatocellular carcinoma and its premalignant lesion", PATHOLOGY INTERNATIONAL, CARLTON SOUTH, AU, vol. 49, no. 2, 1 February 1999 (1999-02-01), pages 147 - 151, XP009159532, ISSN: 1320-5463, [retrieved on 20020301], DOI: 10.1046/J.1440-1827.1999.00836.X *
YANG ET AL: "Leukocyte cell-derived chemotaxin 2 (LECT2) gene expression can influence intravasation and metastatic ability of hepatoma cells through in vivo study", AMERICAN ASSOCIATION FOR CANCER RESEARCH. PROCEEDINGS OF THE ANNUAL MEETING, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 50, 1 January 2009 (2009-01-01), XP009167645, ISSN: 0197-016X *

Also Published As

Publication number Publication date
TW201200151A (en) 2012-01-01
EP2515930A1 (en) 2012-10-31
CN102802658A (en) 2012-11-28
WO2011076095A8 (en) 2011-09-29
WO2011076095A1 (en) 2011-06-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20120622

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20130313

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/00 20060101ALI20130307BHEP

Ipc: A61K 38/19 20060101AFI20130307BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20131015