EP2515930A4 - Verfahren und zusammensetzungen im zusammenhang mit reduzierter met-phosphorylierung durch aus leukozyten gewonnenes chemotaxin 2 in tumorzellen - Google Patents

Verfahren und zusammensetzungen im zusammenhang mit reduzierter met-phosphorylierung durch aus leukozyten gewonnenes chemotaxin 2 in tumorzellen

Info

Publication number
EP2515930A4
EP2515930A4 EP10838658.2A EP10838658A EP2515930A4 EP 2515930 A4 EP2515930 A4 EP 2515930A4 EP 10838658 A EP10838658 A EP 10838658A EP 2515930 A4 EP2515930 A4 EP 2515930A4
Authority
EP
European Patent Office
Prior art keywords
methods
tumor cells
leukocyte cell
compositions related
met phosphorylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10838658.2A
Other languages
English (en)
French (fr)
Other versions
EP2515930A1 (de
Inventor
Min-Liang Kuo
Yu-Ling Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TTY Biopharm Co Ltd
Original Assignee
TTY Biopharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TTY Biopharm Co Ltd filed Critical TTY Biopharm Co Ltd
Publication of EP2515930A1 publication Critical patent/EP2515930A1/de
Publication of EP2515930A4 publication Critical patent/EP2515930A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP10838658.2A 2009-12-21 2010-12-20 Verfahren und zusammensetzungen im zusammenhang mit reduzierter met-phosphorylierung durch aus leukozyten gewonnenes chemotaxin 2 in tumorzellen Withdrawn EP2515930A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28862709P 2009-12-21 2009-12-21
PCT/CN2010/079993 WO2011076095A1 (en) 2009-12-21 2010-12-20 Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells

Publications (2)

Publication Number Publication Date
EP2515930A1 EP2515930A1 (de) 2012-10-31
EP2515930A4 true EP2515930A4 (de) 2013-04-10

Family

ID=44194951

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10838658.2A Withdrawn EP2515930A4 (de) 2009-12-21 2010-12-20 Verfahren und zusammensetzungen im zusammenhang mit reduzierter met-phosphorylierung durch aus leukozyten gewonnenes chemotaxin 2 in tumorzellen

Country Status (4)

Country Link
EP (1) EP2515930A4 (de)
CN (1) CN102802658A (de)
TW (1) TW201200151A (de)
WO (1) WO2011076095A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102559739B (zh) * 2012-01-20 2014-06-25 宁波大学 重组人源lect2蛋白在毕赤酵母中的表达及纯化方法
WO2013158485A1 (en) 2012-04-18 2013-10-24 Massachusetts Institute Of Technology Menainv and cancer invasion and metastasis
CA2925107A1 (en) 2013-10-02 2015-04-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the lect2 gene
US10745702B2 (en) 2015-04-08 2020-08-18 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the LECT2 gene

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2347761A1 (de) * 2008-09-22 2011-07-27 TTY Biopharm Company Limited Zusammensetzung mit hemmender wirkung auf die pathologische angiogenese

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5645829A (en) 1993-06-18 1997-07-08 Beth Israel Hospital Association Mesothelial cell gene therapy
ES2325344B1 (es) * 2004-11-02 2010-06-09 Univ Madrid Autonoma Inhibidores de angiogenesis multifuncionales y multivalentes.
CN1785426A (zh) * 2005-10-27 2006-06-14 南京大学 一种抑制肿瘤血管新生的方法
EP2056812A1 (de) * 2006-08-31 2009-05-13 Abraxis BioScience, LLC Verfahren zur hemmung der angiogenese und behandlung von erkrankungen im zusammenhang mti angiogenese

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2347761A1 (de) * 2008-09-22 2011-07-27 TTY Biopharm Company Limited Zusammensetzung mit hemmender wirkung auf die pathologische angiogenese

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
See also references of WO2011076095A1 *
UCHIDA T ET AL: "Expression pattern of a newly recognized protein, LECT2, in hepatocellular carcinoma and its premalignant lesion", PATHOLOGY INTERNATIONAL, CARLTON SOUTH, AU, vol. 49, no. 2, 1 February 1999 (1999-02-01), pages 147 - 151, XP009159532, ISSN: 1320-5463, [retrieved on 20020301], DOI: 10.1046/J.1440-1827.1999.00836.X *
YANG ET AL: "Leukocyte cell-derived chemotaxin 2 (LECT2) gene expression can influence intravasation and metastatic ability of hepatoma cells through in vivo study", AMERICAN ASSOCIATION FOR CANCER RESEARCH. PROCEEDINGS OF THE ANNUAL MEETING, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 50, 1 January 2009 (2009-01-01), XP009167645, ISSN: 0197-016X *

Also Published As

Publication number Publication date
TW201200151A (en) 2012-01-01
EP2515930A1 (de) 2012-10-31
CN102802658A (zh) 2012-11-28
WO2011076095A8 (en) 2011-09-29
WO2011076095A1 (en) 2011-06-30

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Legal Events

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DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20130313

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/00 20060101ALI20130307BHEP

Ipc: A61K 38/19 20060101AFI20130307BHEP

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Effective date: 20131015