EP2531855A4 - Ki-67-assay für immunsystemzustand eines patienten - Google Patents

Ki-67-assay für immunsystemzustand eines patienten

Info

Publication number: EP2531855A4
Authority: EP; European Patent Office
Prior art keywords: assay; immune system; system status; patient immune; patient
Prior art date: 2010-02-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP11740332.9A

Other languages

English (en)

French (fr)

Other versions

EP2531855A1 (de

Inventor

Denis V Baev

Franco Lori

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

VIROSTATICS Srl

Original Assignee

VIROSTATICS Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-02-04

Filing date

2011-02-03

Publication date

2013-08-07

2011-02-03 Application filed by VIROSTATICS Srl filed Critical VIROSTATICS Srl

2012-12-12 Publication of EP2531855A1 publication Critical patent/EP2531855A1/de

2013-08-07 Publication of EP2531855A4 publication Critical patent/EP2531855A4/de

Status Withdrawn legal-status Critical Current

Links

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70514—CD4
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70517—CD8
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Immunology (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP11740332.9A 2010-02-04 2011-02-03 Ki-67-assay für immunsystemzustand eines patienten Withdrawn EP2531855A4 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US30140010P	2010-02-04	2010-02-04
PCT/US2011/023547 WO2011097345A1 (en)	2010-02-04	2011-02-03	Ki-67 assay for patient immune system status

Publications (2)

Publication Number	Publication Date
EP2531855A1 EP2531855A1 (de)	2012-12-12
EP2531855A4 true EP2531855A4 (de)	2013-08-07

Family

ID=44355763

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP11740332.9A Withdrawn EP2531855A4 (de)	2010-02-04	2011-02-03	Ki-67-assay für immunsystemzustand eines patienten

Country Status (2)

Country	Link
EP (1)	EP2531855A4 (de)
WO (1)	WO2011097345A1 (de)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050215479A1 (en) *	1999-04-15	2005-09-29	Monash University	Diagnostic indicator of thymic function
WO2009120341A2 (en) *	2008-03-24	2009-10-01	University Of South Florida	Biomarkers for predicting response to immunosuppressive therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2611861C (en) *	2005-06-08	2017-11-28	The Brigham And Women's Hospital, Inc.	Methods and compositions for the treatment of persistent infections

2011
- 2011-02-03 EP EP11740332.9A patent/EP2531855A4/de not_active Withdrawn
- 2011-02-03 WO PCT/US2011/023547 patent/WO2011097345A1/en not_active Ceased

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050215479A1 (en) *	1999-04-15	2005-09-29	Monash University	Diagnostic indicator of thymic function
WO2009120341A2 (en) *	2008-03-24	2009-10-01	University Of South Florida	Biomarkers for predicting response to immunosuppressive therapy

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANA SOUSA ET AL: "Viral Load HIV-1 and HIV-2 but Only Indirectly to the Immune Activation in the Pathogenesis of CD4 T Cell Depletion Is Linked Directly to the Viral Load.", JOURNAL OF IMMUNOLOGY, vol. 169, 15 September 2002 (2002-09-15), pages 3400 - 3406, XP055068484 *
KLEIN ET AL: "A new quantitative test method for cell proliferation based on detection of the Ki-67 protein.", JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE, vol. 11, no. 2, 1 February 2000 (2000-02-01), pages 125 - 132, XP055068482, ISSN: 0957-4530 *
N. SACHSENBERG ET AL: "Turnover of CD4+ and CD8+ T Lymphocytes in HIV-1 Infection as Measured by Ki-67 Antigen", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 375, no. 6528, 20 April 1998 (1998-04-20), pages 196 - 1303, XP055068363, ISSN: 1476-4687, DOI: 10.1126/science.271.5249.669 *
See also references of WO2011097345A1 *

Also Published As

Publication number	Publication date
EP2531855A1 (de)	2012-12-12
WO2011097345A1 (en)	2011-08-11

Legal Events

Date	Code	Title	Description
2012-11-09	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2012-12-12	17P	Request for examination filed	Effective date: 20120903
2012-12-12	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2012-12-26	RIN1	Information on inventor provided before grant (corrected)	Inventor name: LORI, FRANCO Inventor name: BAEV, DENIS, V.
2013-05-08	DAX	Request for extension of the european patent (deleted)
2013-08-07	A4	Supplementary search report drawn up and despatched	Effective date: 20130709
2013-08-07	RIC1	Information provided on ipc code assigned before grant	Ipc: G01N 33/68 20060101AFI20130703BHEP
2014-04-16	RIN1	Information on inventor provided before grant (corrected)	Inventor name: BAEV, DENIS, V. Inventor name: LORI, FRANCO
2014-07-04	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2014-08-06	18D	Application deemed to be withdrawn	Effective date: 20140206

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