EP2585811A4 - Procédé pour l'analyse d'échantillons biologiques par imagerie spectrale - Google Patents

Procédé pour l'analyse d'échantillons biologiques par imagerie spectrale Download PDF

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Publication number
EP2585811A4
EP2585811A4 EP11799012.7A EP11799012A EP2585811A4 EP 2585811 A4 EP2585811 A4 EP 2585811A4 EP 11799012 A EP11799012 A EP 11799012A EP 2585811 A4 EP2585811 A4 EP 2585811A4
Authority
EP
European Patent Office
Prior art keywords
spectral imaging
biological specimens
analyzing biological
analyzing
specimens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11799012.7A
Other languages
German (de)
English (en)
Other versions
EP2585811A1 (fr
Inventor
Max Diem
Benjamin Bird
Milos Miljkovic
Stanley H. Remiszewski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Northeastern University Boston
Cireca Theranostics LLC
Original Assignee
Northeastern University Boston
Cireca Theranostics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northeastern University Boston, Cireca Theranostics LLC filed Critical Northeastern University Boston
Publication of EP2585811A1 publication Critical patent/EP2585811A1/fr
Publication of EP2585811A4 publication Critical patent/EP2585811A4/fr
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N2021/3595—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using FTIR
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3581—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using far infrared light; using Terahertz radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods
    • G01N2201/1293—Using chemometrical methods resolving multicomponent spectra
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods
    • G01N2201/1296—Using chemometrical methods using neural networks
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10024—Color image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10048—Infrared image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Multimedia (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Processing Or Creating Images (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Image Processing (AREA)
EP11799012.7A 2010-06-25 2011-06-24 Procédé pour l'analyse d'échantillons biologiques par imagerie spectrale Withdrawn EP2585811A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35860610P 2010-06-25 2010-06-25
PCT/US2011/041884 WO2011163624A1 (fr) 2010-06-25 2011-06-24 Procédé pour l'analyse d'échantillons biologiques par imagerie spectrale

Publications (2)

Publication Number Publication Date
EP2585811A1 EP2585811A1 (fr) 2013-05-01
EP2585811A4 true EP2585811A4 (fr) 2017-12-20

Family

ID=45371844

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11799012.7A Withdrawn EP2585811A4 (fr) 2010-06-25 2011-06-24 Procédé pour l'analyse d'échantillons biologiques par imagerie spectrale

Country Status (9)

Country Link
EP (1) EP2585811A4 (fr)
JP (2) JP6019017B2 (fr)
KR (1) KR20130056886A (fr)
AU (1) AU2011270731A1 (fr)
BR (1) BR112012033200A2 (fr)
CA (1) CA2803933C (fr)
IL (1) IL223853A (fr)
MX (1) MX337696B (fr)
WO (1) WO2011163624A1 (fr)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9025850B2 (en) 2010-06-25 2015-05-05 Cireca Theranostics, Llc Method for analyzing biological specimens by spectral imaging
US9129371B2 (en) 2010-06-25 2015-09-08 Cireca Theranostics, Llc Method for analyzing biological specimens by spectral imaging
WO2013039587A2 (fr) * 2011-06-24 2013-03-21 Northeastern University Correction de phase visant à compenser les distorsions de la réflexion de spectres optiques
WO2013142366A1 (fr) * 2012-03-19 2013-09-26 Genetic Innovations, Inc. Dispositifs, systèmes et procédés de coloration virtuelle
JP5861225B2 (ja) * 2012-06-07 2016-02-16 国立大学法人鳥取大学 被検サンプル組織体中の検体細胞の有無判別方法および装置
JP6006036B2 (ja) * 2012-08-17 2016-10-12 オリンパス株式会社 分光スペクトル解析方法
US9798918B2 (en) 2012-10-05 2017-10-24 Cireca Theranostics, Llc Method and system for analyzing biological specimens by spectral imaging
BR112015024134A2 (pt) * 2013-03-19 2017-07-18 Cireca Theranostics Llc método para classificar a amostra biológica, sistema para classificar a amostra biológica e produto de programa de computador
ES2982998T3 (es) * 2013-09-19 2024-10-21 Oreal Sistemas y métodos para medir y categorizar colores y espectros de superficies
US9269014B2 (en) 2013-09-24 2016-02-23 Corning Incorporated Hyperspectral detector systems and methods using context-image fusion
CN103489194A (zh) * 2013-09-30 2014-01-01 河海大学 基于安全半监督支持向量机的遥感影像变化检测方法
JP6499643B2 (ja) 2013-10-01 2019-04-10 ベンタナ メディカル システムズ， インコーポレイテッド ラインベースの画像位置合わせ及び交差画像注釈デバイス、システム、及び方法
WO2015128946A1 (fr) 2014-02-25 2015-09-03 オリンパス株式会社 Procédé d'analyse de spectre optique
JP2015178986A (ja) * 2014-03-19 2015-10-08 株式会社島津製作所 赤外顕微鏡
JP6451741B2 (ja) * 2014-07-11 2019-01-16 株式会社ニコン 画像解析装置、撮像システム、手術支援システム、及び画像解析プログラム
AU2015292225B2 (en) * 2014-07-21 2020-06-25 7386819 Manitoba Ltd. Method and device for bone scan in meat
JP2016035394A (ja) * 2014-08-01 2016-03-17 パイオニア株式会社 テラヘルツ波撮像装置及びテラヘルツ波撮像方法
EP3222997A4 (fr) * 2014-11-21 2017-11-29 Sumitomo Electric Industries, Ltd. Procédé d'évaluation de qualité et dispositif d'évaluation de qualité
KR101735464B1 (ko) 2014-12-17 2017-05-15 한밭대학교 산학협력단 유기물의 존재 또는 생물의 생사 측정 장치 및 방법
US10460439B1 (en) 2015-08-12 2019-10-29 Cireca Theranostics, Llc Methods and systems for identifying cellular subtypes in an image of a biological specimen
GB2545877B (en) * 2015-09-10 2021-09-15 Sierra Medical Ltd ATR-FTIR computational analysis of Barrett's esophagus and esophageal cancers
KR101793609B1 (ko) 2015-09-11 2017-11-06 연세대학교 산학협력단 다중 광학 융합영상 기반 실시간으로 뇌종양을 진단하는 방법 및 장치
CA3001763C (fr) * 2015-10-28 2020-10-27 Ventana Medical Systems, Inc. Procedes et systemes d'analyse de la qualite des tissus par spectroscopie en moyen infrarouge
JP6776672B2 (ja) 2016-07-08 2020-10-28 住友電気工業株式会社 品質評価方法及び品質評価装置
JP6422616B1 (ja) * 2016-12-22 2018-11-14 国立大学法人 筑波大学 データ作成方法及びデータ使用方法
JP6975418B2 (ja) * 2017-03-24 2021-12-01 株式会社Ｓｃｒｅｅｎホールディングス 領域判定方法
JP7189621B2 (ja) 2017-05-22 2022-12-14 ラ トローブ ユニバーシティ 光学顕微鏡の画像コントラスト増強
EP3664705A4 (fr) * 2017-08-09 2021-09-29 Allen Institute Systèmes, dispositifs et procédés de traitement d'image pour générer une image présentant un marquage prédictif
PT3685144T (pt) * 2017-09-21 2024-12-27 Vital Biosciences Inc Imagiologia de tecidos biológicos e outros alvos
JPWO2019073666A1 (ja) * 2017-10-11 2020-12-03 株式会社ニコン 判定装置、判定方法、および判定プログラム
JP7200945B2 (ja) * 2017-12-01 2023-01-10 ソニーグループ株式会社 画像着色装置、画像着色方法、プログラム、及び画像着色システム
CN117958872A (zh) 2017-12-05 2024-05-03 Devicor医疗产业收购公司 具有应用成像的活检装置
JP6951753B2 (ja) * 2018-03-27 2021-10-20 エバ・ジャパン 株式会社 情報探索システム及びプログラム
JP6669189B2 (ja) * 2018-04-09 2020-03-18 株式会社島津製作所 赤外顕微鏡
JP7235272B2 (ja) * 2018-05-16 2023-03-08 株式会社アドダイス 画像処理装置及び検査システム
CN109087341B (zh) * 2018-06-07 2022-07-05 华南农业大学 一种近距离高光谱相机与测距传感器的融合方法
GB2577349B (en) 2018-09-18 2023-06-14 Univ Oxford Innovation Ltd Radiomic signature of adipose
GB201817092D0 (en) * 2018-10-19 2018-12-05 Cancer Research Tech Ltd Apparatus and method for wide-field hyperspectral imaging
JP7466540B2 (ja) 2018-11-29 2024-04-12 ラ トローブ ユニバーシティ 構造を識別する方法
EP3887799B1 (fr) * 2018-11-29 2024-04-24 La Trobe University Procédé automatisé d'identification d'une structure
WO2020110069A1 (fr) 2018-11-29 2020-06-04 La Trobe University Procédé et système de microscopie
CN113544492B (zh) 2018-11-29 2024-10-01 乐卓博大学 鉴定结构的方法
JP7473223B2 (ja) * 2019-07-24 2024-04-23 学校法人 埼玉医科大学 推定器学習装置、推定器学習方法、及び、推定器学習プログラム
KR102091832B1 (ko) * 2019-08-05 2020-03-20 주식회사 에프앤디파트너스 멀티미디어 정보를 이용한 휴대용 체외진단키트 해석장치
EP4022286A1 (fr) * 2019-08-28 2022-07-06 Ventana Medical Systems, Inc. Évaluation sans étiquette de l'expression de biomarqueurs par spectroscopie vibrationnelle
CN114303203A (zh) * 2019-08-28 2022-04-08 文塔纳医疗系统公司 使用振动光谱法评估抗原修复和靶标修复进展定量
KR102347442B1 (ko) * 2019-11-08 2022-01-05 한국광기술원 중적외선을 이용한 암종 컬러검출장치 및 방법
KR102723111B1 (ko) * 2019-12-11 2024-10-30 (주)미래컴퍼니 테라헤르츠파를 이용한 검사 시스템
KR102752192B1 (ko) * 2019-12-11 2025-01-10 (주)미래컴퍼니 테라헤르츠파를 이용한 기판 검사 시스템
KR102648092B1 (ko) * 2019-12-16 2024-03-18 (주)미래컴퍼니 테라헤르츠파를 이용한 검사 시스템
KR102648081B1 (ko) * 2019-12-13 2024-03-18 (주)미래컴퍼니 테라헤르츠파를 이용한 검사 시스템
KR102648099B1 (ko) * 2019-12-16 2024-03-18 (주)미래컴퍼니 테라헤르츠파를 이용한 검사 시스템
KR102676218B1 (ko) * 2019-12-16 2024-06-19 (주)미래컴퍼니 테라헤르츠파를 이용한 검사 시스템
KR102697403B1 (ko) * 2019-12-16 2024-08-22 (주)미래컴퍼니 테라헤르츠파를 이용한 검사 시스템
GB202006494D0 (en) * 2020-05-01 2020-06-17 Imperial College Innovations Ltd Processing 1h-nmr spectral data
JP2020204624A (ja) * 2020-09-18 2020-12-24 パイオニア株式会社 テラヘルツ波撮像装置及びテラヘルツ波撮像方法
US11959835B2 (en) * 2020-10-23 2024-04-16 Clarapath, Inc. Preliminary diagnoses of cut tissue sections
KR102441907B1 (ko) * 2021-07-08 2022-09-08 가톨릭대학교 산학협력단 암 진단을 위한 이미지 분류 장치 및 이미지 분류 방법
WO2023096971A1 (fr) * 2021-11-24 2023-06-01 Applied Materials, Inc. Détection à résolution hyperspectrale à base d'intelligence artificielle de cellules anormales
KR102735781B1 (ko) * 2022-07-20 2024-11-28 주식회사 사이버네틱스이미징시스템즈 병리학 시료의 스캔 이미징 및 라만 신호 동시 획득 시스템 및 방법
WO2024248436A1 (fr) * 2023-05-26 2024-12-05 주식회사 이모코그 Méthode et appareil de diagnostic d'une maladie à l'aide d'un modèle d'intelligence artificielle
WO2025249837A1 (fr) * 2024-05-27 2025-12-04 주식회사 이모코그 Méthode et appareil de diagnostic de maladies à l'aide d'un modèle d'intelligence artificielle

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003672A1 (fr) * 1991-08-20 1993-03-04 Redd Douglas C B Analyse optique histochimique, detection in vivo et guidage en temps reel pour l'ablation de tissus alteres au moyen d'un systeme de detection spectroscopique raman
US5713364A (en) * 1995-08-01 1998-02-03 Medispectra, Inc. Spectral volume microprobe analysis of materials
US6002476A (en) * 1998-04-22 1999-12-14 Chemicon Inc. Chemical imaging system
US6215554B1 (en) * 1999-08-26 2001-04-10 Yi Zhang Laser diagnostic unit for detecting carcinosis
US20030026762A1 (en) * 1999-05-05 2003-02-06 Malmros Mark K. Bio-spectral imaging system and methods for diagnosing cell disease state
US20040186382A1 (en) * 1997-01-13 2004-09-23 Medispectra, Inc. Spectral volume microprobe arrays
US20060281068A1 (en) * 2005-06-09 2006-12-14 Chemimage Corp. Cytological methods for detecting a disease condition such as malignancy by Raman spectroscopic imaging
US20090002702A1 (en) * 2007-02-14 2009-01-01 Chemimage Corporation Distinguishing between renal oncocytoma and chromophobe renal cell carcinoma using raman molecular imaging
US20090112101A1 (en) * 2006-07-31 2009-04-30 Furness Iii Thomas A Method, apparatus, and article to facilitate evaluation of objects using electromagnetic energy
WO2009146425A1 (fr) * 2008-05-29 2009-12-03 Northeastern University Procédé de reconstitution de spectres cellulaires utiles pour détecter des désordres cellulaires

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037772A (en) * 1998-01-06 2000-03-14 Arch Development Corp. Fast spectroscopic imaging system
JPH11283019A (ja) * 1998-03-31 1999-10-15 Fuji Photo Film Co Ltd 画像解析装置
IL132687A0 (en) * 1999-11-01 2001-03-19 Keren Mechkarim Ichilov Pnimit System and method for evaluating body fluid samples
JP2004053498A (ja) * 2002-07-23 2004-02-19 Matsushita Electric Ind Co Ltd 顕微鏡画像解析装置とその画像解析方法
JP2005058378A (ja) * 2003-08-08 2005-03-10 Olympus Corp 手術用観察システム
JP4673000B2 (ja) * 2004-05-21 2011-04-20 株式会社キーエンス 蛍光顕微鏡、蛍光顕微鏡装置を使用した表示方法、蛍光顕微鏡画像表示プログラム及びコンピュータで読み取り可能な記録媒体並びに記憶した機器
JP2006026015A (ja) * 2004-07-14 2006-02-02 Fuji Photo Film Co Ltd 光断層画像取得システム
EP1844426A4 (fr) * 2005-02-01 2016-09-07 Amnis Corp Analyse sanguine et cellulaire au moyen d'un cytometre en flux imageur
JP4669330B2 (ja) * 2005-06-17 2011-04-13 日本放送協会 ２次元再生等化器および２次元再生等化方法
JP5135882B2 (ja) * 2007-05-22 2013-02-06 株式会社豊田中央研究所 物体識別装置及びプログラム
JP5146667B2 (ja) * 2008-06-13 2013-02-20 花王株式会社 肌のなめらかさの評価方法
US9117133B2 (en) * 2008-06-18 2015-08-25 Spectral Image, Inc. Systems and methods for hyperspectral imaging
JPWO2010046968A1 (ja) * 2008-10-21 2012-03-15 西日本高速道路エンジニアリング四国株式会社 コンクリート構造物の診断装置および診断方法

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003672A1 (fr) * 1991-08-20 1993-03-04 Redd Douglas C B Analyse optique histochimique, detection in vivo et guidage en temps reel pour l'ablation de tissus alteres au moyen d'un systeme de detection spectroscopique raman
US5713364A (en) * 1995-08-01 1998-02-03 Medispectra, Inc. Spectral volume microprobe analysis of materials
US20040186382A1 (en) * 1997-01-13 2004-09-23 Medispectra, Inc. Spectral volume microprobe arrays
US6002476A (en) * 1998-04-22 1999-12-14 Chemicon Inc. Chemical imaging system
US20030026762A1 (en) * 1999-05-05 2003-02-06 Malmros Mark K. Bio-spectral imaging system and methods for diagnosing cell disease state
US6215554B1 (en) * 1999-08-26 2001-04-10 Yi Zhang Laser diagnostic unit for detecting carcinosis
US20060281068A1 (en) * 2005-06-09 2006-12-14 Chemimage Corp. Cytological methods for detecting a disease condition such as malignancy by Raman spectroscopic imaging
US20090112101A1 (en) * 2006-07-31 2009-04-30 Furness Iii Thomas A Method, apparatus, and article to facilitate evaluation of objects using electromagnetic energy
US20090002702A1 (en) * 2007-02-14 2009-01-01 Chemimage Corporation Distinguishing between renal oncocytoma and chromophobe renal cell carcinoma using raman molecular imaging
WO2009146425A1 (fr) * 2008-05-29 2009-12-03 Northeastern University Procédé de reconstitution de spectres cellulaires utiles pour détecter des désordres cellulaires

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2011163624A1 *

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IL223853A (en) 2017-12-31
EP2585811A1 (fr) 2013-05-01
CA2803933A1 (fr) 2011-12-29
JP6019017B2 (ja) 2016-11-02
JP2013535014A (ja) 2013-09-09
AU2011270731A8 (en) 2013-03-07
BR112012033200A2 (pt) 2016-12-06
AU2011270731A1 (en) 2013-02-07
KR20130056886A (ko) 2013-05-30
JP2016028250A (ja) 2016-02-25
CA2803933C (fr) 2017-10-03
MX337696B (es) 2016-03-15
WO2011163624A1 (fr) 2011-12-29
JP6366556B2 (ja) 2018-08-01
MX2012015240A (es) 2013-12-02

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