EP2630479A4 - Appareil et procédé de mesure de cinétiques de liaison avec un capteur résonant - Google Patents
Appareil et procédé de mesure de cinétiques de liaison avec un capteur résonantInfo
- Publication number
- EP2630479A4 EP2630479A4 EP11835164.2A EP11835164A EP2630479A4 EP 2630479 A4 EP2630479 A4 EP 2630479A4 EP 11835164 A EP11835164 A EP 11835164A EP 2630479 A4 EP2630479 A4 EP 2630479A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- binding kinetics
- measuring binding
- resonant sensor
- resonant
- sensor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
- G01N29/02—Analysing fluids
- G01N29/022—Fluid sensors based on microsensors, e.g. quartz crystal-microbalance [QCM], surface acoustic wave [SAW] devices, tuning forks, cantilevers, flexural plate wave [FPW] devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
- G01N29/02—Analysing fluids
- G01N29/036—Analysing fluids by measuring frequency or resonance of acoustic waves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/02—Indexing codes associated with the analysed material
- G01N2291/025—Change of phase or condition
- G01N2291/0255—(Bio)chemical reactions, e.g. on biosensors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/02—Indexing codes associated with the analysed material
- G01N2291/025—Change of phase or condition
- G01N2291/0256—Adsorption, desorption, surface mass change, e.g. on biosensors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/04—Wave modes and trajectories
- G01N2291/042—Wave modes
- G01N2291/0426—Bulk waves, e.g. quartz crystal microbalance, torsional waves
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Acoustics & Sound (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- High Energy & Nuclear Physics (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40504810P | 2010-10-20 | 2010-10-20 | |
| PCT/US2011/057147 WO2012054758A2 (fr) | 2010-10-20 | 2011-10-20 | Appareil et procédé de mesure de cinétiques de liaison avec un capteur résonant |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP2630479A2 EP2630479A2 (fr) | 2013-08-28 |
| EP2630479A4 true EP2630479A4 (fr) | 2015-07-22 |
| EP2630479B1 EP2630479B1 (fr) | 2020-04-08 |
Family
ID=45973349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP11835164.2A Active EP2630479B1 (fr) | 2010-10-20 | 2011-10-20 | Appareil et procédé de mesure de cinétiques de liaison et de concentration avec un capteur résonant |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8409875B2 (fr) |
| EP (1) | EP2630479B1 (fr) |
| CN (1) | CN103403538B (fr) |
| DK (1) | DK2630479T3 (fr) |
| ES (1) | ES2804799T3 (fr) |
| WO (1) | WO2012054758A2 (fr) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2976673B1 (fr) * | 2011-06-16 | 2014-02-14 | Univ Cergy Pontoise | Capteur piezo-electrique pour la detection et la caracterisation d'au moins un element biochimique. |
| US9354202B2 (en) * | 2011-09-21 | 2016-05-31 | David Lawrence Medin | Detecting mass on a MEMS biooscillating resonator array |
| KR101732193B1 (ko) * | 2011-10-21 | 2017-05-04 | 삼성전자주식회사 | 충전 전력 제어 방법 및 이를 위한 무선 충전 장치 |
| FR2986320B1 (fr) * | 2012-01-27 | 2014-12-26 | Commissariat Energie Atomique | Dispositif de mesure a capteurs resonants |
| DK2972295T3 (en) * | 2013-03-15 | 2019-03-25 | Qorvo Us Inc | ACOUSTIC THIN VOLUME RESONATOR WITH SIGNAL AMPLIFIER |
| US10234425B2 (en) | 2013-03-15 | 2019-03-19 | Qorvo Us, Inc. | Thin film bulk acoustic resonator with signal enhancement |
| CN110694700A (zh) | 2013-05-23 | 2020-01-17 | Qorvo美国公司 | 两部分总成 |
| US11476605B2 (en) | 2013-05-23 | 2022-10-18 | Qorvo Biotechnologies, Llc | Interconnect device and module using same |
| PL3000133T3 (pl) | 2013-05-23 | 2021-09-20 | Qorvo Us, Inc. | Czujnik piezoelektryczny |
| WO2014190238A1 (fr) * | 2013-05-23 | 2014-11-27 | Rapid Diagnostek | Système de module de capteur à résonateur et procédé |
| WO2015073496A1 (fr) * | 2013-11-12 | 2015-05-21 | Rapid Diagnostek | Détecteurs possédant un étalonnage interne ou des contrôles positifs |
| US10379093B2 (en) * | 2013-12-06 | 2019-08-13 | Battelle Memorial Institute | Method and device for detecting odorants in hydrocarbon gases |
| PL3194961T3 (pl) | 2014-09-15 | 2021-08-02 | Qorvo Us, Inc. | Cienkowarstwowy rezonator z akustyczną falą objętościową ze wzmocnieniem sygnału |
| WO2016044132A1 (fr) | 2014-09-15 | 2016-03-24 | Rapid Diagnostek, Inc. | Détection de masse par couplage redox |
| CN106468648B (zh) | 2015-08-19 | 2019-09-10 | 财团法人工业技术研究院 | 微粒子侦测器及筛选元件的制造方法 |
| US10063210B2 (en) | 2015-10-14 | 2018-08-28 | Qorvo Us, Inc. | Methods for producing piezoelectric bulk and crystalline seed layers of different C-axis orientation distributions |
| CN108463720B (zh) | 2015-10-21 | 2021-03-23 | Qorvo美国公司 | 具有声学振动的剪切模式和纵向模式的增强反射的谐振器结构 |
| US10352904B2 (en) | 2015-10-26 | 2019-07-16 | Qorvo Us, Inc. | Acoustic resonator devices and methods providing patterned functionalization areas |
| CN108139364A (zh) | 2015-10-28 | 2018-06-08 | Qorvo美国公司 | 具有baw谐振器和通过衬底的流体通孔的传感器设备 |
| US10393704B2 (en) | 2015-10-30 | 2019-08-27 | Qorvo Us, Inc. | Multi-frequency BAW mixing and sensing system and method |
| WO2017075354A1 (fr) | 2015-10-30 | 2017-05-04 | Qorvo Us, Inc. | Dispositif fluidique comprenant des résonateurs à ondes acoustiques de volume le long de surfaces de canal opposées |
| US10533972B2 (en) | 2015-11-02 | 2020-01-14 | Qorvo Us, Inc. | Fluidic device with fluid port orthogonal to functionalized active region |
| CN108474764B (zh) | 2015-11-06 | 2021-12-10 | Qorvo美国公司 | 声学谐振器设备和提供气密性及表面功能化的制造方法 |
| WO2017083131A1 (fr) | 2015-11-09 | 2017-05-18 | Qorvo Us, Inc. | Capteur de baw ayant une région active à surface augmentée |
| US10371667B2 (en) | 2015-11-16 | 2019-08-06 | Qorvo Us, Inc. | BAW sensor with passive mixing structures |
| DK3377886T3 (da) | 2015-11-20 | 2020-10-12 | Qorvo Us Inc | Akustisk resonator med reduceret mekanisk spænding af et aktivt område for forbedret forskydningsmodusrespons |
| US10330642B2 (en) | 2015-12-14 | 2019-06-25 | Qorvo Us, Inc. | BAW sensor device with peel-resistant wall structure |
| US10866216B2 (en) | 2015-12-15 | 2020-12-15 | Qorvo Biotechnologies, Llc | Temperature compensation and operational configuration for bulk acoustic wave resonator devices |
| US11435394B1 (en) * | 2016-01-28 | 2022-09-06 | Anritsu Company | Accelerated measurements through adaptive test parameter selection |
| US10330643B2 (en) | 2016-02-04 | 2019-06-25 | Qorvo Us, Inc. | BAW sensing and filtration device and related methods |
| CN109073601B (zh) | 2016-03-11 | 2021-10-29 | Qorvo美国公司 | 具有增加的动态测量范围的baw传感器流体装置 |
| WO2017189512A1 (fr) | 2016-04-26 | 2017-11-02 | Qorvo Us, Inc. | Résonateur pour détecter une liaison de molécule unique |
| US12360125B2 (en) | 2016-07-25 | 2025-07-15 | Zomedica Biotechnologies Llc | Biosensor for coagulation testing |
| US10267770B2 (en) | 2016-07-27 | 2019-04-23 | Qorvo Us, Inc. | Acoustic resonator devices and methods with noble metal layer for functionalization |
| JP7007362B2 (ja) | 2016-08-11 | 2022-01-24 | コーボ ユーエス，インコーポレイティド | 機能化材料を制御して配置した弾性共振装置 |
| US10739211B2 (en) * | 2016-12-16 | 2020-08-11 | Vdw Design, Llc | Chipless RFID-based temperature threshold sensor |
| EP3343220B1 (fr) * | 2016-12-27 | 2020-04-08 | IMEC vzw | Caractérisation de bioparticules |
| JP6469736B2 (ja) * | 2017-01-17 | 2019-02-13 | 太陽誘電株式会社 | センサ回路およびセンシング方法 |
| US10852264B2 (en) | 2017-07-18 | 2020-12-01 | Boston Scientific Scimed, Inc. | Systems and methods for analyte sensing in physiological gas samples |
| US11381212B2 (en) | 2018-03-21 | 2022-07-05 | Qorvo Us, Inc. | Piezoelectric bulk layers with tilted c-axis orientation and methods for making the same |
| US11824511B2 (en) | 2018-03-21 | 2023-11-21 | Qorvo Us, Inc. | Method for manufacturing piezoelectric bulk layers with tilted c-axis orientation |
| JP2021528664A (ja) | 2018-07-06 | 2021-10-21 | コーボ ユーエス，インコーポレイティド | ダイナミックレンジが拡大されたバルク音響波共振器 |
| EP3861329A1 (fr) | 2018-11-27 | 2021-08-11 | Boston Scientific Scimed Inc. | Systèmes et méthodes de détection d'un état de santé |
| CN113196047B (zh) * | 2018-12-18 | 2024-08-16 | 明尼苏达大学董事会 | 用于测量化学传感器元件的动力学响应的系统和方法 |
| US11325121B2 (en) | 2019-03-29 | 2022-05-10 | Qorvo Us, Inc. | Analyte depletion for sensor equilibration |
| US11940414B2 (en) | 2019-03-29 | 2024-03-26 | Zomedica Biotechnologies Llc | Crowded sensor |
| US12445109B2 (en) | 2019-07-31 | 2025-10-14 | QXONIX Inc. | Structures, acoustic wave resonators, layers, devices and systems |
| US12451860B2 (en) | 2019-07-31 | 2025-10-21 | QXONIX Inc. | Structures, acoustic wave resonators, devices and systems |
| WO2021021723A1 (fr) | 2019-07-31 | 2021-02-04 | QXONIX Inc. | Structures, dispositifs et systèmes de dispositif acoustique |
| US12431861B2 (en) | 2019-07-31 | 2025-09-30 | Qxoniix Inc. | Layers, structures, acoustic wave resonators, devices and systems |
| US11401601B2 (en) | 2019-09-13 | 2022-08-02 | Qorvo Us, Inc. | Piezoelectric bulk layers with tilted c-axis orientation and methods for making the same |
| US12100920B2 (en) | 2019-12-19 | 2024-09-24 | Zomedica Biotechnologies Llc | Coaxial connector |
| US12613212B2 (en) | 2020-05-01 | 2026-04-28 | Regents Of The University Of Minnesota | Non-invasive bladder cancer detection system via liquid and gaseous phase analysis |
| US12480907B2 (en) | 2021-04-16 | 2025-11-25 | Regents Of The University Of Minnesota | Systems utilizing graphene varactor hysteresis effects for sample characterization |
| WO2023022796A2 (fr) * | 2021-07-09 | 2023-02-23 | The Trustees Of Columbia University In The City Of New York | Systèmes et procédés de détection de masse basés sur des résonateurs piézoélectriques intégrés fonctionnalisés |
| GB2629413A (en) * | 2023-04-27 | 2024-10-30 | The Univ Of Durham | Method and apparatus for detecting a target in a complex fluid |
| CN117192141B (zh) * | 2023-11-07 | 2024-01-23 | 北京众驰伟业科技发展有限公司 | 全自动凝血测试仪的质量控制系统及方法 |
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2011
- 2011-10-20 EP EP11835164.2A patent/EP2630479B1/fr active Active
- 2011-10-20 WO PCT/US2011/057147 patent/WO2012054758A2/fr not_active Ceased
- 2011-10-20 CN CN201180061100.XA patent/CN103403538B/zh active Active
- 2011-10-20 US US13/278,032 patent/US8409875B2/en active Active
- 2011-10-20 DK DK11835164.2T patent/DK2630479T3/da active
- 2011-10-20 ES ES11835164T patent/ES2804799T3/es active Active
-
2013
- 2013-04-01 US US13/854,617 patent/US20140127826A1/en not_active Abandoned
- 2013-04-29 US US13/872,577 patent/US20140154697A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| US8409875B2 (en) | 2013-04-02 |
| WO2012054758A2 (fr) | 2012-04-26 |
| US20140154697A1 (en) | 2014-06-05 |
| WO2012054758A3 (fr) | 2012-06-21 |
| US20140127826A1 (en) | 2014-05-08 |
| CN103403538B (zh) | 2016-06-01 |
| DK2630479T3 (da) | 2020-07-20 |
| EP2630479A2 (fr) | 2013-08-28 |
| EP2630479B1 (fr) | 2020-04-08 |
| CN103403538A (zh) | 2013-11-20 |
| ES2804799T3 (es) | 2021-02-09 |
| US20120100636A1 (en) | 2012-04-26 |
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