EP2692858A4 - Procédé de fabrication d'un modèle de peau artificiel, et modèle de peau artificiel - Google Patents

Procédé de fabrication d'un modèle de peau artificiel, et modèle de peau artificiel

Info

Publication number: EP2692858A4
Authority: EP; European Patent Office
Prior art keywords: artificial skin; skin model; manufacturing; manufacturing artificial; model
Prior art date: 2011-03-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP12764146.2A

Other languages

German (de)

English (en)

Other versions

EP2692858B1 (fr

EP2692858A1 (fr

Inventor

Mitsuru Akashi

Michiya Matsusaki

Takeshi Sakura

Koji Hashimoto

Yuji Shirakata

Satoshi Hirakawa

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Toray Industries Inc

University of Osaka NUC

Original Assignee

Osaka University NUC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-03-29

Filing date

2012-03-29

Publication date

2014-11-05

2012-03-29 Application filed by Osaka University NUC filed Critical Osaka University NUC

2014-02-05 Publication of EP2692858A1 publication Critical patent/EP2692858A1/fr

2014-11-05 Publication of EP2692858A4 publication Critical patent/EP2692858A4/fr

2017-06-14 Application granted granted Critical

2017-06-14 Publication of EP2692858B1 publication Critical patent/EP2692858B1/fr

Status Not-in-force legal-status Critical Current

2032-03-29 Anticipated expiration legal-status Critical

Links

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C12N5/0698—Skin equivalents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1192—Lymphatic cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/28—Vascular endothelial cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/04—Screening or testing on artificial tissues
- C12N2503/06—Screening or testing on artificial skin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Hematology (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Organic Chemistry (AREA)
Food Science & Technology (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
General Engineering & Computer Science (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Materials For Medical Uses (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP12764146.2A 2011-03-29 2012-03-29 Procédé de fabrication d'un modèle de peau artificiel, et modèle de peau artificiel Not-in-force EP2692858B1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2011072207A JP2012205516A (ja)	2011-03-29	2011-03-29	人工皮膚モデルの製造方法、及び人工皮膚モデル
PCT/JP2012/058329 WO2012133629A1 (fr)	2011-03-29	2012-03-29	Procédé de fabrication d'un modèle de peau artificiel, et modèle de peau artificiel

Publications (3)

Publication Number	Publication Date
EP2692858A1 EP2692858A1 (fr)	2014-02-05
EP2692858A4 true EP2692858A4 (fr)	2014-11-05
EP2692858B1 EP2692858B1 (fr)	2017-06-14

Family

ID=46931331

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP12764146.2A Not-in-force EP2692858B1 (fr)	2011-03-29	2012-03-29	Procédé de fabrication d'un modèle de peau artificiel, et modèle de peau artificiel

Country Status (4)

Country	Link
US (1)	US10073085B2 (fr)
EP (1)	EP2692858B1 (fr)
JP (1)	JP2012205516A (fr)
WO (1)	WO2012133629A1 (fr)

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JP2012205516A (ja)	2011-03-29	2012-10-25	Osaka Univ	人工皮膚モデルの製造方法、及び人工皮膚モデル
US20150250925A1 (en) *	2012-09-04	2015-09-10	Biomedical Technology Hybrid Co., Ltd.	Artificial skin tissue, artificial skin model and manufacturing method therefor
JP6288691B2 (ja) *	2013-05-20	2018-03-07	国立大学法人東京大学	胚様体に対する空間分化誘導制御方法及びその装置
CN105705626B (zh)	2013-10-29	2018-11-16	学校法人北里研究所	细胞或组织的玻璃化冷冻保存用工具
WO2015072164A1 (fr) *	2013-11-14	2015-05-21	国立大学法人大阪大学	Cellule revêtue d'un film de revêtement comprenant du collagène et son procédé de production
JP6674686B2 (ja) *	2014-08-22	2020-04-01	国立大学法人大阪大学	被覆細胞、その製造方法及び被覆細胞を用いた三次元組織体の製造方法
JP6619345B2 (ja)	2014-09-23	2019-12-11	国立大学法人東京大学	人工三次元組織の製造方法、人工三次元組織灌流デバイス、人工三次元組織を用いた薬剤評価方法
US10799615B2 (en)	2014-12-08	2020-10-13	Osaka University	Artificial tissue and method for producing same
US9625449B2 (en)	2014-12-23	2017-04-18	Colgate-Palmolive Company	Determining the bioavailability of zinc (II) ions
US9435745B2 (en)	2014-12-23	2016-09-06	Colgate-Palmolive Company	Measuring the rate of release of metal ions
US9354219B1 (en)	2014-12-23	2016-05-31	Colgate-Palmolive Company	Detecting stannous ions
WO2017126532A1 (fr) *	2016-01-20	2017-07-27	国立大学法人東京大学	Tissu tridimensionnel artificiel et son procédé de fabrication, dispositif de perfusion pour le tissu tridimensionnel artificiel, et procédé d'évaluation de médicaments utilisant le tissu tridimensionnel artificiel
EP3421588B1 (fr) *	2016-02-22	2024-04-10	Osaka University	Procédé de production de tissu cellulaire tridimensionnel
EP3447143A4 (fr) *	2016-04-19	2019-11-20	Toppan Printing Co., Ltd.	Procédé d'évaluation de médicament anticancéreux
JPWO2017221870A1 (ja) *	2016-06-21	2019-04-11	株式会社オーガンテクノロジーズ	毛包、皮脂腺、および毛穴を有する人工皮膚の製造方法
US20190195753A1 (en) *	2016-08-10	2019-06-27	Shiseido Company, Ltd.	Transparent skin sample
KR102288612B1 (ko)	2017-06-12	2021-08-11	미쓰비시 세이시 가부시키가이샤	세포 또는 조직의 동결 보존용 지그
WO2019143498A1 (fr) *	2018-01-22	2019-07-25	ClearIt, LLC	Procédés et compositions pour la simulation du compartiment dermique
JP6945487B2 (ja)	2018-04-26	2021-10-06	三菱製紙株式会社	細胞又は組織の凍結保存液
JP2022514758A (ja)	2018-12-19	2022-02-15	クリアイットエルエルシー	印加電場を用いた入れ墨除去システム及び方法
JP7144380B2 (ja)	2019-08-23	2022-09-29	三菱製紙株式会社	細胞又は組織の凍結保存用治具
EP4023289A4 (fr)	2019-08-29	2023-06-14	National University Corporation Ehime University	Procédé de production de tissu cultivé, et préparation pour application externe
US11213467B2 (en)	2019-11-07	2022-01-04	Amyris, Inc.	Compositions and methods for delivering cannabinoids to skin
LU502391B1 (en)	2022-06-28	2024-01-09	Univerza V Mariboru	A complex in vitro model of human skin, a process for preparation and use thereof
JP7471579B1 (ja) *	2023-04-28	2024-04-22	ティシューバイネット株式会社	立体細胞構造体を製造する方法

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WO2009118283A1 (fr) *	2008-03-28	2009-10-01	Technische Universität Berlin	Procédés pour produire des microfollicules capillaires et des papilles de novo et leur utilisation pour des essais in vitro et des implantations in vivo

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2011
- 2011-03-29 JP JP2011072207A patent/JP2012205516A/ja active Pending
2012
- 2012-03-29 EP EP12764146.2A patent/EP2692858B1/fr not_active Not-in-force
- 2012-03-29 US US14/008,348 patent/US10073085B2/en active Active
- 2012-03-29 WO PCT/JP2012/058329 patent/WO2012133629A1/fr not_active Ceased

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US20070207540A1 (en) *	2006-03-02	2007-09-06	Osaka University	Method of producing three-dimensional tissue and method of producing extracellular matrix used in the same
WO2009118283A1 (fr) *	2008-03-28	2009-10-01	Technische Universität Berlin	Procédés pour produire des microfollicules capillaires et des papilles de novo et leur utilisation pour des essais in vitro et des implantations in vivo

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See also references of WO2012133629A1 *
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Also Published As

Publication number	Publication date
US10073085B2 (en)	2018-09-11
EP2692858B1 (fr)	2017-06-14
EP2692858A1 (fr)	2014-02-05
WO2012133629A1 (fr)	2012-10-04
US20140024010A1 (en)	2014-01-23
JP2012205516A (ja)	2012-10-25

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