EP2742154A4 - Biomarkerzusammensetzungen und verfahren damit - Google Patents
Biomarkerzusammensetzungen und verfahren damitInfo
- Publication number
- EP2742154A4 EP2742154A4 EP12821745.2A EP12821745A EP2742154A4 EP 2742154 A4 EP2742154 A4 EP 2742154A4 EP 12821745 A EP12821745 A EP 12821745A EP 2742154 A4 EP2742154 A4 EP 2742154A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- biomarker compositions
- biomarker
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161521333P | 2011-08-08 | 2011-08-08 | |
| US201161523763P | 2011-08-15 | 2011-08-15 | |
| US201161526623P | 2011-08-23 | 2011-08-23 | |
| US201161529762P | 2011-08-31 | 2011-08-31 | |
| US201161534352P | 2011-09-13 | 2011-09-13 | |
| US201161537462P | 2011-09-21 | 2011-09-21 | |
| US201161542639P | 2011-10-03 | 2011-10-03 | |
| US201161551674P | 2011-10-26 | 2011-10-26 | |
| US201161559676P | 2011-11-14 | 2011-11-14 | |
| US201261612111P | 2012-03-16 | 2012-03-16 | |
| US201261619803P | 2012-04-03 | 2012-04-03 | |
| PCT/US2012/050030 WO2013022995A2 (en) | 2011-08-08 | 2012-08-08 | Biomarker compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2742154A2 EP2742154A2 (de) | 2014-06-18 |
| EP2742154A4 true EP2742154A4 (de) | 2015-08-12 |
Family
ID=47669214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP12821745.2A Withdrawn EP2742154A4 (de) | 2011-08-08 | 2012-08-08 | Biomarkerzusammensetzungen und verfahren damit |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2742154A4 (de) |
| JP (1) | JP2014522993A (de) |
| KR (1) | KR20140067001A (de) |
| CN (1) | CN103874770A (de) |
| AU (1) | AU2012294458A1 (de) |
| BR (1) | BR112014002975A2 (de) |
| CA (1) | CA2844671A1 (de) |
| WO (1) | WO2013022995A2 (de) |
Families Citing this family (160)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0913578A2 (pt) | 2008-05-14 | 2017-06-06 | Dermtech Int | diagnose de melanoma e lentigo solar por análise de ácido nucléico |
| US9128101B2 (en) | 2010-03-01 | 2015-09-08 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
| WO2011127219A1 (en) | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings | Circulating biomarkers for disease |
| CA2877721A1 (en) | 2012-06-27 | 2014-01-03 | Berg Llc | Use of markers in the diagnosis and treatment of prostate cancer |
| US10942184B2 (en) | 2012-10-23 | 2021-03-09 | Caris Science, Inc. | Aptamers and uses thereof |
| CN103160509B (zh) * | 2013-03-07 | 2015-02-18 | 新乡医学院第一附属医院 | 一种与食管癌术后早期复发和预后相关的miRNA标志物及其应用 |
| PT3527670T (pt) * | 2013-03-15 | 2024-01-18 | Beth Israel Deaconess Medical Ct Inc | Biogénese de mirna em exossomas para diagnóstico e terapia |
| CN104076151B (zh) * | 2013-03-29 | 2017-04-12 | 复旦大学附属华山医院 | 一种用于胶质瘤早期诊断的试剂盒 |
| MX363679B (es) * | 2013-04-29 | 2019-03-29 | Apogenix Ag | Metodo para diagnosticar cancer. |
| EP2994545B1 (de) | 2013-05-10 | 2019-03-20 | University Of Southern California | Dna-methylierungsbiomarker für blasenkrebs |
| US10301681B2 (en) * | 2013-08-06 | 2019-05-28 | Exosome Diagnostics, Inc. | Methods of treating a subject with a high gleason score prostate cancer |
| JP6612232B2 (ja) * | 2013-08-28 | 2019-11-27 | クラウン バイオサイエンス インコーポレイテッド(タイカン) | 対象のマルチキナーゼ阻害剤に対する応答性を予測する遺伝子発現シグネチャ、及びその使用 |
| WO2015031694A2 (en) * | 2013-08-28 | 2015-03-05 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| WO2015068772A1 (ja) * | 2013-11-06 | 2015-05-14 | Jsr株式会社 | 分離方法、検出方法、シグナル測定方法、疾患の判定方法、疾患治療薬の薬効評価方法、キット及び液状組成物 |
| FR3014198B1 (fr) * | 2013-12-03 | 2017-03-03 | Biomerieux Sa | Procede d'isolement d'exosomes |
| WO2015083829A1 (ja) * | 2013-12-06 | 2015-06-11 | 国立大学法人東京大学 | バルブ、流体制御構造、流体デバイス及びバルブの製造方法 |
| AU2014373927B2 (en) * | 2013-12-30 | 2018-03-22 | Genomatix | Prostate cancer gene profiles and methods of using the same |
| WO2015101988A1 (en) | 2013-12-31 | 2015-07-09 | Yeda Research And Development Co. Ltd. | Diagnosis of systemic lupus erythematosus using oligonucleotides antigens |
| WO2015117164A1 (en) * | 2014-02-03 | 2015-08-06 | Memorial Sloan-Kettering Cancer Center | Tumor-associated macrophages and methods and compositions for targeting cancer therapy and identifying potential responders |
| JP6728536B2 (ja) * | 2014-03-31 | 2020-07-22 | ゾール メディカル コーポレイションZOLL Medical Corporation | 蘇生後症候群を治療するための炎症性バイオマーカーの血液濾過 |
| EP3137909B1 (de) | 2014-04-29 | 2018-06-06 | Apogenix AG | Diagnostischer anti-cd95l-antikörper |
| KR20170007317A (ko) * | 2014-05-01 | 2017-01-18 | 스티칭 브이유엠씨 | 바이오마커로서의 소형 ncrna |
| ES2481819B1 (es) * | 2014-06-12 | 2015-04-01 | Sistemas Genómicos, S.L. | Método de evaluación para evaluar una posibilidad de cáncer de mama |
| CN111996254B (zh) | 2014-06-12 | 2024-10-18 | 东丽株式会社 | 前列腺癌的检测试剂盒或装置以及检测方法 |
| US20160038608A1 (en) * | 2014-08-07 | 2016-02-11 | National Taiwan University | Silica-based mesoporous carrier and delivery method of using the same |
| KR102328327B1 (ko) * | 2014-09-26 | 2021-11-22 | 소마로직, 인크. | 심혈관 위험 사건 예측 및 이의 용도 |
| KR101596166B1 (ko) | 2014-10-07 | 2016-02-19 | 가톨릭대학교 산학협력단 | 유방암 진단 및 치료를 위한 마이크로 rna의 용도 |
| CN104313171A (zh) * | 2014-11-06 | 2015-01-28 | 南京大学 | 一种诊断神经胶质瘤的microRNA分子标记物及其应用 |
| EP3230314B1 (de) * | 2014-12-08 | 2023-05-03 | Berg LLC | Verwendung von markern einschliesslich filamin a bei der diagnose und behandlung von prostatakrebs |
| CN105807063B (zh) * | 2014-12-29 | 2018-02-06 | 中国人民解放军第二军医大学 | Cd63在制备肝脏疾病诊断试剂盒或制备预防或治疗肝脏疾病药物中的应用 |
| CN104548134A (zh) * | 2015-01-04 | 2015-04-29 | 中国人民解放军第二军医大学 | miR-144及其抑制剂的应用 |
| US20180148783A1 (en) * | 2015-01-05 | 2018-05-31 | The Johns Hopkins University | Method of epigenetic analysis for determining clinical genetic risk |
| WO2016121821A1 (ja) * | 2015-01-27 | 2016-08-04 | Jsr株式会社 | 分離方法、検出方法、シグナル測定方法、疾患の判定方法、薬効評価方法、キット、液状組成物及び検体希釈液 |
| US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
| US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| CN107530376A (zh) | 2015-02-18 | 2018-01-02 | 恩立夫克治疗有限责任公司 | 用于癌症治疗的联合免疫疗法和细胞因子控制疗法 |
| WO2016139659A1 (en) | 2015-03-01 | 2016-09-09 | Immunarray Ltd. | Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens |
| AU2016229076B2 (en) | 2015-03-09 | 2022-01-20 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| CN104714032B (zh) * | 2015-04-02 | 2015-09-16 | 闫星宇 | 用于产后子痫诊断的标志物及其检测试剂 |
| IL287500B2 (en) | 2015-04-21 | 2023-12-01 | Enlivex Therapeutics Rdo Ltd | Therapeutic pooled blood apoptotic cell preparations and uses thereof |
| US10709428B2 (en) | 2015-05-01 | 2020-07-14 | Dermtech, Inc. | Non-invasive skin collection system |
| CN108271413A (zh) * | 2015-05-20 | 2018-07-10 | Jsr株式会社 | 分离方法、检测方法、信号测定方法、疾病的判定方法、药效评价方法、试剂盒、液态组合物以及检体稀释液 |
| IL256175B2 (en) | 2015-06-10 | 2024-10-01 | Univ Texas | Using exosomes to treat the disease |
| CN104992058B (zh) * | 2015-06-25 | 2017-08-01 | 成都厚立信息技术有限公司 | 疾病风险调整模型建立方法 |
| IL318703A (en) | 2015-06-29 | 2025-03-01 | Caris Science Inc | Therapeutic oligonucleotides |
| CN105177117A (zh) * | 2015-07-03 | 2015-12-23 | 张理义 | 重症抑郁障碍生物标记物、筛选方法及试剂盒 |
| CN106350578A (zh) * | 2015-07-13 | 2017-01-25 | 中国人民解放军第二军医大学 | Ny-eso-1在微卫星不稳定性肠癌的诊断和治疗中的应用 |
| EP3328873B1 (de) | 2015-07-28 | 2025-09-17 | Caris Science, Inc. | Gezielte oligonukleotide |
| CN105039342B (zh) * | 2015-08-06 | 2017-12-01 | 李家平 | 能抑制MAT2A基因表达的siRNA及其应用 |
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| CN105067822B (zh) * | 2015-08-12 | 2017-05-24 | 中山大学附属肿瘤医院 | 用于食管癌诊断的标志物 |
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| CN105907875A (zh) * | 2016-06-13 | 2016-08-31 | 武汉泰安康生物科技有限公司 | 一种筛选肾癌外周血miRNA标志物的方法及肾癌标志物miR-378 |
| JP6980219B2 (ja) * | 2016-08-22 | 2021-12-15 | いであ株式会社 | がんを検出、又はがんの進行期を判定する方法 |
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| CN108165635B (zh) * | 2016-12-07 | 2021-07-13 | 南京农业大学 | Kiaa1462基因启动子区变异位点及其在提高鹅产蛋性能上的应用 |
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2844671A1 (en) | 2013-02-14 |
| AU2012294458A1 (en) | 2014-02-27 |
| JP2014522993A (ja) | 2014-09-08 |
| WO2013022995A3 (en) | 2013-04-04 |
| KR20140067001A (ko) | 2014-06-03 |
| EP2742154A2 (de) | 2014-06-18 |
| BR112014002975A2 (pt) | 2017-03-01 |
| WO2013022995A2 (en) | 2013-02-14 |
| CN103874770A (zh) | 2014-06-18 |
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