EP2768544A4 - Absorbierbares in-situ-gelbildendes system, herstellungsverfahren dafür und verwendung davon - Google Patents

Absorbierbares in-situ-gelbildendes system, herstellungsverfahren dafür und verwendung davon

Info

Publication number
EP2768544A4
EP2768544A4 EP11874179.2A EP11874179A EP2768544A4 EP 2768544 A4 EP2768544 A4 EP 2768544A4 EP 11874179 A EP11874179 A EP 11874179A EP 2768544 A4 EP2768544 A4 EP 2768544A4
Authority
EP
European Patent Office
Prior art keywords
absorbable
manufacturing
gelification
situ
situ gelification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11874179.2A
Other languages
English (en)
French (fr)
Other versions
EP2768544A1 (de
Inventor
Shalaby W Shalaby
Joel Corbett
Jason Olbrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poly Med Inc
Original Assignee
Poly Med Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poly Med Inc filed Critical Poly Med Inc
Publication of EP2768544A1 publication Critical patent/EP2768544A1/de
Publication of EP2768544A4 publication Critical patent/EP2768544A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
EP11874179.2A 2011-10-17 2011-10-17 Absorbierbares in-situ-gelbildendes system, herstellungsverfahren dafür und verwendung davon Withdrawn EP2768544A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/056537 WO2013058726A1 (en) 2011-10-17 2011-10-17 Absorbable in situ gel-forming system, method of making and use thereof

Publications (2)

Publication Number Publication Date
EP2768544A1 EP2768544A1 (de) 2014-08-27
EP2768544A4 true EP2768544A4 (de) 2015-06-24

Family

ID=48141188

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11874179.2A Withdrawn EP2768544A4 (de) 2011-10-17 2011-10-17 Absorbierbares in-situ-gelbildendes system, herstellungsverfahren dafür und verwendung davon

Country Status (5)

Country Link
EP (1) EP2768544A4 (de)
JP (1) JP5989126B2 (de)
CN (2) CN107252498B (de)
CA (1) CA2852386C (de)
WO (1) WO2013058726A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150305892A1 (en) * 2014-04-25 2015-10-29 Abbott Cardiovascular Systems Inc. Methods and Devices for Treating a Bodily Lumen with In Situ Generated Structural Support
CN104189951B (zh) * 2014-09-19 2017-06-30 赣南师范学院 一种注射用快速形成原位小分子水凝胶的液态制剂及其制备方法和应用
CN104383276A (zh) * 2014-10-27 2015-03-04 济南高达信息技术有限公司 一种治疗蜘蛛痣的中药口服液制剂及其制备方法
US10786515B2 (en) 2015-08-03 2020-09-29 Tolmar International Limited Liquid polymer delivery system for extended administration of drugs
SG11201804037XA (en) * 2015-11-16 2018-06-28 Evonik Roehm Gmbh Injection solution comprising a non-nucleoside reverse-transcriptase inhibitor and poly(lactide-co-glycolide)
CN110087705B (zh) * 2016-05-03 2022-08-05 Bvw控股公司 多相凝胶
WO2020190606A1 (en) * 2019-03-15 2020-09-24 Poly-Med, Inc. In situ gel-forming delivery systems, methods and compositions

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0952171A2 (de) * 1998-01-29 1999-10-27 Poly-Med Inc. Hydrogelbildende, selbst-solvatisierende, absorbierbare Polyestercopolymere sowie Verfahren zu deren Verwendung
WO2000071170A1 (en) * 1999-05-21 2000-11-30 Micro Therapeutics, Inc. Novel high viscosity embolizing compositions
WO2004039411A2 (en) * 2002-10-31 2004-05-13 Pfizer Products Inc. Solid and semi-solid polymeric ionic conjugates
EP2100905A2 (de) * 2008-03-12 2009-09-16 Poly-Med, Inc. Wasserquellbare, segmentierte, aliphatische Polyurethane und Polyurethan-Harnstoffe

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11510837A (ja) * 1995-07-28 1999-09-21 フォーカル，インコーポレイテッド 薬物送達のための制御された放出薬剤および組織処置薬剤としての使用のためのマルチブロック生分解性ヒドロゲル
ATE269121T1 (de) * 1996-07-29 2004-07-15 Micro Therapeutics Inc Kit aus drei glasfläschen zur vaskulären embolisierung unter verwendung eines dimethylsulfoxyd enthaltenden mittels
US5854382A (en) * 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses
WO2000000222A1 (en) * 1998-06-30 2000-01-06 Amgen Inc. Thermosensitive biodegradable hydrogels for sustained delivery of biologically active agents
US6245740B1 (en) * 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
US7649023B2 (en) * 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
CN1950114A (zh) * 2004-05-12 2007-04-18 苏尔莫迪克斯公司 用于医疗物品的天然生物可降解的多糖涂层
US20050255091A1 (en) * 2004-05-14 2005-11-17 Loomis Gary L Hydrogels for biomedical applications
CN1899264A (zh) * 2006-07-20 2007-01-24 上海交通大学 温度敏感型水凝胶释药体系及其制备方法
CN100562358C (zh) * 2007-05-17 2009-11-25 浙江大学 以水凝胶微球为模板制备中空微球的方法
CN101721349B (zh) * 2008-10-16 2011-07-20 常州百瑞吉生物医药有限公司 可注射原位交联水凝胶及其制备方法和用途
CN102146200B (zh) * 2011-04-19 2012-08-22 复旦大学 一种基于化学交联凝胶颗粒的温敏性水凝胶及其制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0952171A2 (de) * 1998-01-29 1999-10-27 Poly-Med Inc. Hydrogelbildende, selbst-solvatisierende, absorbierbare Polyestercopolymere sowie Verfahren zu deren Verwendung
WO2000071170A1 (en) * 1999-05-21 2000-11-30 Micro Therapeutics, Inc. Novel high viscosity embolizing compositions
WO2004039411A2 (en) * 2002-10-31 2004-05-13 Pfizer Products Inc. Solid and semi-solid polymeric ionic conjugates
EP2100905A2 (de) * 2008-03-12 2009-09-16 Poly-Med, Inc. Wasserquellbare, segmentierte, aliphatische Polyurethane und Polyurethan-Harnstoffe

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2013058726A1 *

Also Published As

Publication number Publication date
EP2768544A1 (de) 2014-08-27
WO2013058726A1 (en) 2013-04-25
CA2852386C (en) 2019-05-21
JP5989126B2 (ja) 2016-09-07
JP2014532082A (ja) 2014-12-04
CN107252498A (zh) 2017-10-17
CN107252498B (zh) 2021-02-19
CN103998069A (zh) 2014-08-20
CA2852386A1 (en) 2013-04-25

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