EP2841607A4 - Verfahren, systeme und vorrichtung für zyklotronherstellung von technetium-99m - Google Patents

Verfahren, systeme und vorrichtung für zyklotronherstellung von technetium-99m

Info

Publication number
EP2841607A4
EP2841607A4 EP13781369.7A EP13781369A EP2841607A4 EP 2841607 A4 EP2841607 A4 EP 2841607A4 EP 13781369 A EP13781369 A EP 13781369A EP 2841607 A4 EP2841607 A4 EP 2841607A4
Authority
EP
European Patent Office
Prior art keywords
technétium
cyclotronic
systems
production
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP13781369.7A
Other languages
English (en)
French (fr)
Other versions
EP2841607A1 (de
EP2841607B1 (de
Inventor
Paul Schaffer
Francois Benard
Kenneth R Buckley
Victoire Hanemaayer
Cornelia Hoehr Manuela
Julius Alexander Klug
Michael S Kovacs
Thomas J Morley
Thomas J Ruth
John Valliant
Stefan K Zeisler
Maurice G Dodd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Triumf Inc
Original Assignee
Triumf Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP18154518.7A priority Critical patent/EP3389346B1/de
Priority to DK16200459.2T priority patent/DK3197246T3/da
Priority to EP18187378.7A priority patent/EP3461240B1/de
Priority to EP18202130.3A priority patent/EP3454346B1/de
Priority to PL18202130T priority patent/PL3454346T3/pl
Priority to EP16200459.2A priority patent/EP3197246B1/de
Priority to EP22207642.4A priority patent/EP4216680A1/de
Application filed by Triumf Inc filed Critical Triumf Inc
Publication of EP2841607A1 publication Critical patent/EP2841607A1/de
Publication of EP2841607A4 publication Critical patent/EP2841607A4/de
Application granted granted Critical
Publication of EP2841607B1 publication Critical patent/EP2841607B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/14—Treatment of metallic powder
    • B22F1/145—Chemical treatment, e.g. passivation or decarburisation
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D13/00—Electrophoretic coating characterised by the process
    • C25D13/02—Electrophoretic coating characterised by the process with inorganic material
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D13/00—Electrophoretic coating characterised by the process
    • C25D13/22—Servicing or operating apparatus or multistep processes
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21C—NUCLEAR REACTORS
    • G21C1/00—Reactor types
    • G21C1/04—Thermal reactors ; Epithermal reactors
    • G21C1/06—Heterogeneous reactors, i.e. in which fuel and moderator are separated
    • G21C1/08—Heterogeneous reactors, i.e. in which fuel and moderator are separated moderator being highly pressurised, e.g. boiling water reactor, integral super-heat reactor, pressurised water reactor
    • G21C1/10—Heterogeneous reactors, i.e. in which fuel and moderator are separated moderator being highly pressurised, e.g. boiling water reactor, integral super-heat reactor, pressurised water reactor moderator and coolant being different or separated
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F5/00—Transportable or portable shielded containers
    • G21F5/06—Details of, or accessories to, the containers
    • G21F5/14—Devices for handling containers or shipping-casks, e.g. transporting devices loading and unloading, filling of containers
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001—Recovery of specific isotopes from irradiated targets
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21K—HANDLING OF PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K5/00—Irradiation devices
    • G21K5/08—Holders for targets or for other objects to be irradiated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F2998/00—Supplementary information concerning processes or compositions relating to powder metallurgy
    • B22F2998/10—Processes characterised by the sequence of their steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F2999/00—Aspects linked to processes or compositions used in powder metallurgy
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F7/00—Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression
    • B22F7/02—Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression of composite layers
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
    • G21G1/10—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001—Recovery of specific isotopes from irradiated targets
    • G21G2001/0042—Technetium
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H6/00—Targets for producing nuclear reactions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E30/00—Energy generation of nuclear origin
    • Y02E30/30—Nuclear fission reactors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Plasma & Fusion (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Particle Accelerators (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Manufacture Of Metal Powder And Suspensions Thereof (AREA)
  • Physical Vapour Deposition (AREA)
  • Powder Metallurgy (AREA)
  • Electrolytic Production Of Metals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP13781369.7A 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung für zyklotronherstellung von technetium-99m Active EP2841607B1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DK16200459.2T DK3197246T3 (da) 2012-04-27 2013-04-25 Mål og anordning til cyklotronfremstilling af technetium-99m
EP18187378.7A EP3461240B1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung für zyklotronherstellung von technetium-99m
EP18202130.3A EP3454346B1 (de) 2012-04-27 2013-04-25 Vorrichtungen zur cylotronherstellung von technetium-99m
PL18202130T PL3454346T3 (pl) 2012-04-27 2013-04-25 APARAT DO CYKLOTRONOWEGO WYTWARZANIA TECHNETU-99m
EP18154518.7A EP3389346B1 (de) 2012-04-27 2013-04-25 Verfahren für zyklotronherstellung von technetium-99m
EP22207642.4A EP4216680A1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung zur zyklotronherstellung von technetium-99m
EP16200459.2A EP3197246B1 (de) 2012-04-27 2013-04-25 Target und vorrichtung für zyklotronherstellung von technetium-99m

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261639408P 2012-04-27 2012-04-27
US201261640610P 2012-04-30 2012-04-30
PCT/CA2013/000409 WO2013159201A1 (en) 2012-04-27 2013-04-25 Processes, systems, and apparatus for cyclotron production of technetium-99m

Related Child Applications (5)

Application Number Title Priority Date Filing Date
EP22207642.4A Division EP4216680A1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung zur zyklotronherstellung von technetium-99m
EP16200459.2A Division EP3197246B1 (de) 2012-04-27 2013-04-25 Target und vorrichtung für zyklotronherstellung von technetium-99m
EP18187378.7A Division EP3461240B1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung für zyklotronherstellung von technetium-99m
EP18202130.3A Division EP3454346B1 (de) 2012-04-27 2013-04-25 Vorrichtungen zur cylotronherstellung von technetium-99m
EP18154518.7A Division EP3389346B1 (de) 2012-04-27 2013-04-25 Verfahren für zyklotronherstellung von technetium-99m

Publications (3)

Publication Number Publication Date
EP2841607A1 EP2841607A1 (de) 2015-03-04
EP2841607A4 true EP2841607A4 (de) 2015-10-07
EP2841607B1 EP2841607B1 (de) 2016-12-28

Family

ID=49482067

Family Applications (6)

Application Number Title Priority Date Filing Date
EP18154518.7A Active EP3389346B1 (de) 2012-04-27 2013-04-25 Verfahren für zyklotronherstellung von technetium-99m
EP16200459.2A Active EP3197246B1 (de) 2012-04-27 2013-04-25 Target und vorrichtung für zyklotronherstellung von technetium-99m
EP13781369.7A Active EP2841607B1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung für zyklotronherstellung von technetium-99m
EP18187378.7A Active EP3461240B1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung für zyklotronherstellung von technetium-99m
EP22207642.4A Pending EP4216680A1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung zur zyklotronherstellung von technetium-99m
EP18202130.3A Active EP3454346B1 (de) 2012-04-27 2013-04-25 Vorrichtungen zur cylotronherstellung von technetium-99m

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP18154518.7A Active EP3389346B1 (de) 2012-04-27 2013-04-25 Verfahren für zyklotronherstellung von technetium-99m
EP16200459.2A Active EP3197246B1 (de) 2012-04-27 2013-04-25 Target und vorrichtung für zyklotronherstellung von technetium-99m

Family Applications After (3)

Application Number Title Priority Date Filing Date
EP18187378.7A Active EP3461240B1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung für zyklotronherstellung von technetium-99m
EP22207642.4A Pending EP4216680A1 (de) 2012-04-27 2013-04-25 Verfahren, systeme und vorrichtung zur zyklotronherstellung von technetium-99m
EP18202130.3A Active EP3454346B1 (de) 2012-04-27 2013-04-25 Vorrichtungen zur cylotronherstellung von technetium-99m

Country Status (13)

Country Link
US (7) US20130301769A1 (de)
EP (6) EP3389346B1 (de)
JP (5) JP2015523460A (de)
CN (3) CN108160988B (de)
AU (1) AU2013252446A1 (de)
CA (6) CA3030502C (de)
DK (4) DK3197246T3 (de)
ES (2) ES2933507T3 (de)
HU (2) HUE057406T2 (de)
PL (2) PL3454346T3 (de)
PT (2) PT3461240T (de)
RU (2) RU2692729C2 (de)
WO (1) WO2013159201A1 (de)

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CN104488037B (zh) 2012-06-15 2016-12-21 登特国际研究有限公司 用于元素蜕变的设备及方法
US9449726B2 (en) * 2013-05-31 2016-09-20 Washington University 100Mo compounds as accelerator targets for production of 99mTc
ES2870602T3 (es) * 2014-04-24 2021-10-27 Triumf Conjunto de objetivo para la irradiación de molibdeno con haces de partículas y método de fabricación del mismo
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CN106875999B (zh) * 2017-01-03 2019-01-29 中国原子能科学研究院 一种用于辐照生产裂变99Mo的低浓铀铀箔靶件
US11363709B2 (en) 2017-02-24 2022-06-14 BWXT Isotope Technology Group, Inc. Irradiation targets for the production of radioisotopes
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CN108696980A (zh) * 2018-07-05 2018-10-23 厦门大学 一种轰击Mo靶件的方法和高纯度99mTc及其生产方法和应用
EP3608921B1 (de) * 2018-08-06 2020-12-16 Ion Beam Applications S.A. Kapsel für ein targetmaterial und einrichtung zur bestrahlung dieses targetmaterials
CN112789689B (zh) * 2018-08-27 2024-04-09 Bwxt同位素技术集团有限公司 产生放射性同位素的靶辐照系统
TWI684184B (zh) * 2019-01-23 2020-02-01 日商住友重機械工業股份有限公司 自屏蔽迴旋加速器系統
RU2701552C1 (ru) * 2019-01-25 2019-09-30 Федеральное государственное унитарное предприятие "Производственное объединение "Маяк" Способ получения технеция-99m
JP7506055B2 (ja) * 2019-03-28 2024-06-25 住友重機械工業株式会社 ターゲット照射システム、及び固体ターゲットからの放射性同位元素の回収方法
JP6914544B2 (ja) * 2019-06-21 2021-08-04 株式会社千代田テクノル 非破壊検査用放射線源の製造方法及び装置
KR102264831B1 (ko) * 2019-07-29 2021-06-15 한국원자력의학원 빔 조사 효율이 향상된 파우더형 타겟 및 이를 포함하는 핵종 생산 장치 및 생산방법
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CN112102979B (zh) * 2020-07-30 2023-06-16 复旦大学附属肿瘤医院 一种回旋加速器放射性固体靶的靶片自动回收方法
JP7734741B2 (ja) * 2020-08-18 2025-09-05 ノーススター メディカル ラジオアイソトープス リミテッド ライアビリティ カンパニー アイソトープを製造する方法及びシステム
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CN114745840A (zh) * 2022-04-02 2022-07-12 原子高科股份有限公司 回旋加速器靶室及回旋加速器
IT202200009338A1 (it) * 2022-05-06 2023-11-06 Comecer Spa Unita' per manipolare un contenitore per la produzione di radioisotopi
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IT202200020205A1 (it) * 2022-09-30 2024-03-30 Comecer Spa Sistema per il trasferimento e stoccaggio di rifiuti radioattivi per una cella schermata
WO2024143205A1 (ja) * 2022-12-26 2024-07-04 住友重機械工業株式会社 Ｒｉ製造装置

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