EP2900658A4 - Procédés et polymorphes de 5-[4-[4-(5-cyano-1h-indol-3-yl) butyl]-1-pipérazinyl]-2-benzofuran carboxamide et ses sels - Google Patents

Procédés et polymorphes de 5-[4-[4-(5-cyano-1h-indol-3-yl) butyl]-1-pipérazinyl]-2-benzofuran carboxamide et ses sels

Info

Publication number
EP2900658A4
EP2900658A4 EP13842370.2A EP13842370A EP2900658A4 EP 2900658 A4 EP2900658 A4 EP 2900658A4 EP 13842370 A EP13842370 A EP 13842370A EP 2900658 A4 EP2900658 A4 EP 2900658A4
Authority
EP
European Patent Office
Prior art keywords
polymorphs
indol
piperazinyl
cyano
butyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13842370.2A
Other languages
German (de)
English (en)
Other versions
EP2900658A2 (fr
Inventor
Rajan Srinivasan Thirumalai
Sajja Eswaraiah
Sunkara Vishnuvardhan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSN Laboratories Pvt Ltd
Original Assignee
MSN Laboratories Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MSN Laboratories Pvt Ltd filed Critical MSN Laboratories Pvt Ltd
Publication of EP2900658A2 publication Critical patent/EP2900658A2/fr
Publication of EP2900658A4 publication Critical patent/EP2900658A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EP13842370.2A 2012-09-27 2013-09-26 Procédés et polymorphes de 5-[4-[4-(5-cyano-1h-indol-3-yl) butyl]-1-pipérazinyl]-2-benzofuran carboxamide et ses sels Withdrawn EP2900658A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN4014CH2012 2012-09-27
IN4629CH2012 2012-11-06
IN5296CH2012 2012-12-18
PCT/IN2013/000580 WO2014049612A2 (fr) 2012-09-27 2013-09-26 Procédés et polymorphes de 5-[4-[4-(5-cyano-1h-indol-3-yl) butyl]-1-pipérazinyl]-2-benzofuran carboxamide et ses sels

Publications (2)

Publication Number Publication Date
EP2900658A2 EP2900658A2 (fr) 2015-08-05
EP2900658A4 true EP2900658A4 (fr) 2016-07-13

Family

ID=50389086

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13842370.2A Withdrawn EP2900658A4 (fr) 2012-09-27 2013-09-26 Procédés et polymorphes de 5-[4-[4-(5-cyano-1h-indol-3-yl) butyl]-1-pipérazinyl]-2-benzofuran carboxamide et ses sels

Country Status (2)

Country Link
EP (1) EP2900658A4 (fr)
WO (1) WO2014049612A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014040164A1 (fr) 2012-09-12 2014-03-20 Apotex Pharmachem Inc. Procédés de préparation de 3-alkyl-indoles
WO2016128987A1 (fr) * 2015-02-13 2016-08-18 Harman Finochem Limited Procédé de préparation de la base libre 2-benzofurancarboxamide, 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]-1-pipérazinyle], et de son sel chlorhydrate
CN105541811A (zh) * 2016-01-08 2016-05-04 万特制药(海南)有限公司 一种抗抑郁药物维拉佐酮的精制方法
CN106518853A (zh) * 2016-09-22 2017-03-22 北京万全德众医药生物技术有限公司 一种盐酸维拉佐酮杂质的制备方法
WO2023173182A1 (fr) * 2022-03-16 2023-09-21 Eurofarma Laboratórios S.A. Sel de docusate de vilazodone, procédé d'obtention, composition pharmaceutique et utilisation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102794A2 (fr) * 2001-06-19 2002-12-27 Merck Patent Gmbh Formes polymorphes de chlorhydrate de 1-'4-(5-cyanoindol-3-yl)butyl-4-(2-carbamoylbenzofuran-5-yl)piperazine
CN102219783A (zh) * 2011-05-05 2011-10-19 天津市汉康医药生物技术有限公司 盐酸维拉佐酮及其组合物
WO2013156935A1 (fr) * 2012-04-16 2013-10-24 Ranbaxy Laboratories Limited Procédé de préparation de cristaux de chlorhydrate de vilazodone

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9505744B2 (en) * 2011-11-23 2016-11-29 Assia Chemical Industries Ltd. Solid state forms of vilazodone and vilazodone hydrochloride
CN102617558A (zh) * 2012-03-26 2012-08-01 上海泛凯生物医药科技有限公司 一种维拉佐酮的制备方法
CN102977083A (zh) * 2012-12-17 2013-03-20 南京海纳医药科技有限公司 1-[4-(5-氰基吲哚-3-基)丁基]-4-(2-氨甲酰-苯并呋喃-5-基)-哌嗪盐酸盐的新晶型xⅶ及其制备方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102794A2 (fr) * 2001-06-19 2002-12-27 Merck Patent Gmbh Formes polymorphes de chlorhydrate de 1-'4-(5-cyanoindol-3-yl)butyl-4-(2-carbamoylbenzofuran-5-yl)piperazine
CN102219783A (zh) * 2011-05-05 2011-10-19 天津市汉康医药生物技术有限公司 盐酸维拉佐酮及其组合物
WO2013156935A1 (fr) * 2012-04-16 2013-10-24 Ranbaxy Laboratories Limited Procédé de préparation de cristaux de chlorhydrate de vilazodone

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CAIRA: "Crystalline Polymorphism of Organic Compounds", TOPICS IN CURRENT CHEMISTRY, SPRINGER, BERLIN, DE, vol. 198, 1 January 1998 (1998-01-01), pages 163 - 208, XP008166276, ISSN: 0340-1022 *
DATABASE WPI Week 201232, Derwent World Patents Index; AN 2011-P35968 [32], XP002754050 *

Also Published As

Publication number Publication date
EP2900658A2 (fr) 2015-08-05
WO2014049612A3 (fr) 2014-05-22
WO2014049612A2 (fr) 2014-04-03

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