EP2964237A4 - Méthodes destinées à maintenir une population de cellules thérapeutiques sur le site de traitement chez un sujet ayant besoin d'une thérapie cellulaire - Google Patents
Méthodes destinées à maintenir une population de cellules thérapeutiques sur le site de traitement chez un sujet ayant besoin d'une thérapie cellulaireInfo
- Publication number
- EP2964237A4 EP2964237A4 EP14751247.9A EP14751247A EP2964237A4 EP 2964237 A4 EP2964237 A4 EP 2964237A4 EP 14751247 A EP14751247 A EP 14751247A EP 2964237 A4 EP2964237 A4 EP 2964237A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- population
- maintaining
- subject
- methods
- need
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000002659 cell therapy Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361765075P | 2013-02-15 | 2013-02-15 | |
| PCT/US2014/016477 WO2014127232A2 (fr) | 2013-02-15 | 2014-02-14 | Méthodes destinées à maintenir une population de cellules thérapeutiques sur le site de traitement chez un sujet ayant besoin d'une thérapie cellulaire |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2964237A2 EP2964237A2 (fr) | 2016-01-13 |
| EP2964237A4 true EP2964237A4 (fr) | 2016-11-30 |
Family
ID=51354685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP14751247.9A Withdrawn EP2964237A4 (fr) | 2013-02-15 | 2014-02-14 | Méthodes destinées à maintenir une population de cellules thérapeutiques sur le site de traitement chez un sujet ayant besoin d'une thérapie cellulaire |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2964237A4 (fr) |
| CN (1) | CN105228632A (fr) |
| WO (1) | WO2014127232A2 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2978109A1 (fr) * | 2015-03-31 | 2016-10-06 | The University Of North Carolina At Chapel Hill | Vehicules d'apport pour cellules souches et leurs utilisations |
| US20170151416A1 (en) * | 2015-12-01 | 2017-06-01 | Invivo Therapeutics Corporation | Methods and Systems for Delivery of a Trail of a Therapeutic Substance into an Anatomical Space |
| US10676634B2 (en) * | 2018-09-05 | 2020-06-09 | Swimc Llc | Modified latent crosslinker in polymeric systems |
| IT201800020722A1 (it) * | 2018-12-21 | 2020-06-21 | Assunta Borzacchiello | Biomateriale e suo utilizzo nel trattamento di patologie polmonari |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6482231B1 (en) * | 1995-11-20 | 2002-11-19 | Giovanni Abatangelo | Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative |
| WO2004104166A2 (fr) * | 2003-05-07 | 2004-12-02 | La Jolla Institute For Molecular Medicine | Methodes permettant de faciliter la recuperation de fonctions de cellules souches endogenes, implantees ou transplantees au moyen d'un acide hyaluronique de poids moleculaire eleve |
| WO2007070546A2 (fr) * | 2005-12-14 | 2007-06-21 | Anika Therapeutics, Inc. | Implant méniscal de dérivés d'acide hyaluronique destiné au traitement de défauts méniscaux |
| US20090252700A1 (en) * | 2003-01-10 | 2009-10-08 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| KR20130009651A (ko) * | 2011-07-13 | 2013-01-23 | (주)차바이오앤디오스텍 | 콜라겐, 히알루론산 유도체 및 포유류의 탯줄 유래 줄기세포를 포함하는 연골세포치료제 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008109659A2 (fr) * | 2007-03-06 | 2008-09-12 | University Of North Carolina At Chapel Hill | Complexe d'hyaluronanes, autres composants de matrice, hormones et facteurs de croissance pour maintenance, expansion et/ou différenciation de cellules |
| WO2010127254A2 (fr) * | 2009-04-30 | 2010-11-04 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Matériau élastomère, biodégradable, thermosensible et utilisations de celui-ci |
| WO2011072399A1 (fr) * | 2009-12-18 | 2011-06-23 | The Governing Council Of The University Of Toronto | Composition polymère injectable utilisée comme véhicule pour l'administration de cellules |
-
2014
- 2014-02-14 CN CN201480008940.3A patent/CN105228632A/zh active Pending
- 2014-02-14 EP EP14751247.9A patent/EP2964237A4/fr not_active Withdrawn
- 2014-02-14 WO PCT/US2014/016477 patent/WO2014127232A2/fr not_active Ceased
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6482231B1 (en) * | 1995-11-20 | 2002-11-19 | Giovanni Abatangelo | Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative |
| US20090252700A1 (en) * | 2003-01-10 | 2009-10-08 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| WO2004104166A2 (fr) * | 2003-05-07 | 2004-12-02 | La Jolla Institute For Molecular Medicine | Methodes permettant de faciliter la recuperation de fonctions de cellules souches endogenes, implantees ou transplantees au moyen d'un acide hyaluronique de poids moleculaire eleve |
| WO2007070546A2 (fr) * | 2005-12-14 | 2007-06-21 | Anika Therapeutics, Inc. | Implant méniscal de dérivés d'acide hyaluronique destiné au traitement de défauts méniscaux |
| KR20130009651A (ko) * | 2011-07-13 | 2013-01-23 | (주)차바이오앤디오스텍 | 콜라겐, 히알루론산 유도체 및 포유류의 탯줄 유래 줄기세포를 포함하는 연골세포치료제 |
Non-Patent Citations (4)
| Title |
|---|
| DREW KURAITIS ET AL: "Exploiting extracellular matrix-stem cell interactions: A review of natural materials for therapeutic muscle regeneration", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 33, no. 2, 28 September 2011 (2011-09-28), pages 428 - 443, XP028101922, ISSN: 0142-9612, [retrieved on 20111001], DOI: 10.1016/J.BIOMATERIALS.2011.09.078 * |
| GAETANO LA MANNA ET AL: "Mesenchymal Stem Cells in Renal Function Recovery After Acute Kidney Injury: Use of a Differentiating Agent in a Rat Model", CELL TRANSPLANTATION, vol. 20, no. 8, 19 November 2010 (2010-11-19), US, pages 1193 - 1208, XP055309355, ISSN: 0963-6897, DOI: 10.3727/096368910X543394 * |
| GLENN D. PRESTWICH ET AL: "The translational imperative: Making cell therapy simple and effective", ACTA BIOMATERIALIA, vol. 8, no. 12, 7 July 2012 (2012-07-07), NL, pages 4200 - 4207, XP055309337, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2012.06.043 * |
| GLENN D. PRESTWICH: "Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine", JOURNAL OF CONTROLLED RELEASE, vol. 155, no. 2, 1 October 2011 (2011-10-01), pages 193 - 199, XP055011774, ISSN: 0168-3659, DOI: 10.1016/j.jconrel.2011.04.007 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014127232A3 (fr) | 2015-10-29 |
| WO2014127232A2 (fr) | 2014-08-21 |
| CN105228632A (zh) | 2016-01-06 |
| EP2964237A2 (fr) | 2016-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20150828 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| AX | Request for extension of the european patent |
Extension state: BA ME |
|
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20161103 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 35/34 20060101ALI20161025BHEP Ipc: A61K 35/51 20150101ALI20161025BHEP Ipc: A61K 35/36 20060101ALI20161025BHEP Ipc: A61K 35/12 20060101AFI20161025BHEP Ipc: A61K 35/35 20150101ALI20161025BHEP Ipc: A61K 35/32 20060101ALI20161025BHEP Ipc: A61K 35/50 20150101ALI20161025BHEP Ipc: A61K 35/28 20060101ALI20161025BHEP Ipc: A61K 31/728 20060101ALI20161025BHEP Ipc: A61K 35/545 20150101ALI20161025BHEP |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20170603 |