EP2968394A4 - Nouveaux vaccins contre de multiples sous-types du virus de la dengue - Google Patents

Nouveaux vaccins contre de multiples sous-types du virus de la dengue

Info

Publication number
EP2968394A4
EP2968394A4 EP14763126.1A EP14763126A EP2968394A4 EP 2968394 A4 EP2968394 A4 EP 2968394A4 EP 14763126 A EP14763126 A EP 14763126A EP 2968394 A4 EP2968394 A4 EP 2968394A4
Authority
EP
European Patent Office
Prior art keywords
dengue virus
vaccines against
against multiple
multiple subtypes
novel vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14763126.1A
Other languages
German (de)
English (en)
Other versions
EP2968394A1 (fr
Inventor
David Weiner
Jian Yan
Niranjan Sardesai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Inovio Pharmaceuticals Inc
Original Assignee
University of Pennsylvania Penn
Inovio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn, Inovio Pharmaceuticals Inc filed Critical University of Pennsylvania Penn
Priority claimed from PCT/US2014/029341 external-priority patent/WO2014144786A1/fr
Publication of EP2968394A1 publication Critical patent/EP2968394A1/fr
Publication of EP2968394A4 publication Critical patent/EP2968394A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
EP14763126.1A 2013-03-15 2014-03-14 Nouveaux vaccins contre de multiples sous-types du virus de la dengue Withdrawn EP2968394A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361801972P 2013-03-15 2013-03-15
PCT/US2014/029341 WO2014144786A1 (fr) 2013-03-15 2014-03-14 Nouveaux vaccins contre de multiples sous-types du virus de la dengue

Publications (2)

Publication Number Publication Date
EP2968394A1 EP2968394A1 (fr) 2016-01-20
EP2968394A4 true EP2968394A4 (fr) 2016-04-20

Family

ID=54842920

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14763126.1A Withdrawn EP2968394A4 (fr) 2013-03-15 2014-03-14 Nouveaux vaccins contre de multiples sous-types du virus de la dengue

Country Status (6)

Country Link
EP (1) EP2968394A4 (fr)
JP (1) JP6457481B2 (fr)
KR (1) KR20160004267A (fr)
CN (2) CN105246491B (fr)
HK (1) HK1219904A1 (fr)
MX (1) MX365656B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019005378A2 (pt) * 2016-09-19 2019-08-27 The Trustees Of The University Of Pennsylvania molécula de ácido nucleico, composição, e, métodos para prevenir ou tratar uma doença e para induzir uma resposta imune
CN117164681B (zh) * 2023-09-08 2025-07-25 中国人民解放军陆军军医大学 一种基于球形核酸载体的登革多肽疫苗及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009073330A2 (fr) * 2007-11-12 2009-06-11 The Trustees Of The University Of Pennsylvania Nouveaux vaccins pour lutter contre plusieurs sous-types de virus de la grippe
WO2012027473A2 (fr) * 2010-08-24 2012-03-01 The University Of North Carolina At Chapel Hill Compositions immunogènes comprenant des antigènes de la protéine e du virus de la dengue à vecteurs d'alphavirus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2685435T3 (es) * 2008-01-11 2018-10-09 Inovio Pharmaceuticals, Inc. Nuevas vacunas frente a múltiples subtipos del virus del dengue
CN101948850A (zh) * 2010-08-13 2011-01-19 中国疾病预防控制中心病毒病预防控制所 登革病毒病毒样颗粒的制备方法及应用
CA2812306A1 (fr) * 2010-10-01 2012-04-05 University Of Rochester Vaccin contre le flavivirus du domaine iii
CN102363751A (zh) * 2011-03-24 2012-02-29 中山大学 登革病毒样颗粒及其制备方法与应用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009073330A2 (fr) * 2007-11-12 2009-06-11 The Trustees Of The University Of Pennsylvania Nouveaux vaccins pour lutter contre plusieurs sous-types de virus de la grippe
WO2012027473A2 (fr) * 2010-08-24 2012-03-01 The University Of North Carolina At Chapel Hill Compositions immunogènes comprenant des antigènes de la protéine e du virus de la dengue à vecteurs d'alphavirus

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
APT D ET AL: "Tetravalent neutralizing antibody response against four dengue serotypes by a single chimeric dengue envelope antigen", VACCINE, ELSEVIER LTD, GB, vol. 24, no. 3, 16 January 2006 (2006-01-16), pages 335 - 344, XP028010449, ISSN: 0264-410X, [retrieved on 20060116], DOI: 10.1016/J.VACCINE.2005.07.100 *
DOMINICK J LADDY ET AL: "Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens", PLOS ONE, PUBLIC LIBRARY OF SCIENCE, US, vol. 3, no. 6, 1 June 2008 (2008-06-01) - 1 June 2008 (2008-06-01), pages 1 - 8, XP008132555, ISSN: 1932-6203, DOI: 10.1371/JOURNAL.PONE.0002517 *
HUI LU ET AL: "Preliminary evaluation of DNA vaccine candidates encoding dengue-2 prM/E and NS1: Their immunity and protective efficacy in mice", MOLECULAR IMMUNOLOGY., vol. 54, no. 2, 1 June 2013 (2013-06-01), GB, pages 109 - 114, XP055251451, ISSN: 0161-5890, DOI: 10.1016/j.molimm.2012.11.007 *
LADDY ET AL: "Immunogenicity of novel consensus-based DNA vaccines against avian influenza", VACCINE, ELSEVIER LTD, GB, vol. 25, no. 16, 29 March 2007 (2007-03-29), pages 2984 - 2989, XP022004278, ISSN: 0264-410X, DOI: 10.1016/J.VACCINE.2007.01.063 *
LIMA D M ET AL: "A DNA vaccine candidate encoding the structural prM/E proteins elicits a strong immune response and protects mice against dengue-4 virus infection", VACCINE, ELSEVIER, AMSTERDAM, NL, vol. 29, no. 4, 17 January 2011 (2011-01-17), pages 831 - 838, XP027590288, ISSN: 0264-410X, [retrieved on 20110110] *
NIRANJAN Y SARDESAI ET AL: "Electroporation delivery of DNA vaccines: prospects for success", CURRENT OPINION IN IMMUNOLOGY, vol. 23, no. 3, 1 June 2008 (2008-06-01), pages 421 - 429, XP028223967, ISSN: 0952-7915, [retrieved on 20110330], DOI: 10.1016/J.COI.2011.03.008 *
RAMANATHAN M P ET AL: "Coimmunization with an optimized IL15 plasmid adjuvant enhances humoral immunity via stimulating B cells induced by genetically engineered DNA vaccines expressing consensus JEV and WNV E DIII", VACCINE, ELSEVIER LTD, GB, vol. 27, no. 32, 9 July 2009 (2009-07-09), pages 4370 - 4380, XP026210587, ISSN: 0264-410X, [retrieved on 20090306], DOI: 10.1016/J.VACCINE.2009.01.137 *
RAMANATHAN M P ET AL: "Development of a novel DNA SynCon(TM) tetravalent dengue vaccine that elicits immune responses against four serotypes", VACCINE, ELSEVIER LTD, GB, vol. 27, no. 46, 30 October 2009 (2009-10-30), pages 6444 - 6453, XP026704481, ISSN: 0264-410X, [retrieved on 20090704], DOI: 10.1016/J.VACCINE.2009.06.061 *
RAVIPRAKASH K ET AL: "A chimeric tetravalent dengue DNA vaccine elicits neutralizing antibody to all four virus serotypes in rhesus macaques", VIROLOGY, ELSEVIER, AMSTERDAM, NL, vol. 353, no. 1, 15 September 2006 (2006-09-15), pages 166 - 173, XP024896386, ISSN: 0042-6822, [retrieved on 20060915], DOI: 10.1016/J.VIROL.2006.05.005 *
See also references of WO2014144786A1 *
WANG PEI-GANG ET AL: "Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins", PLOS ONE, PUBLIC LIBRARY OF SCIENCE, US, vol. 4, no. 12, 15 December 2009 (2009-12-15), pages E8325 - 1, XP002588733, ISSN: 1932-6203, [retrieved on 20091215], DOI: 10.1371/JOURNAL.PONE.0008325 *

Also Published As

Publication number Publication date
MX365656B (es) 2019-06-10
EP2968394A1 (fr) 2016-01-20
JP6457481B2 (ja) 2019-01-23
HK1219904A1 (zh) 2017-04-21
KR20160004267A (ko) 2016-01-12
CN110055265A (zh) 2019-07-26
JP2016515816A (ja) 2016-06-02
MX2015011485A (es) 2016-09-23
CN105246491A (zh) 2016-01-13
CN105246491B (zh) 2019-04-19

Similar Documents

Publication Publication Date Title
NO2023026I1 (no) Dengue tetravalent vaccine
IL276210B1 (en) Mers-cov vaccine
IL261204A (en) Influenza virus vaccines and their use
IL279395A (en) A vaccine
SG11201509985XA (en) Influenza virus reassortment
ZA201700165B (en) Influenza virus vaccines and uses thereof
ZA201509229B (en) Influenza virus vaccines and uses thereof
SG11201606624WA (en) Antibody moleules to dengue virus and uses thereof
IL240936A0 (en) Redifferentiation of influenza b virus
ZA201508642B (en) Malaria vaccine
SG11201610443WA (en) Influenza virus vaccines and uses thereof
HUE044302T2 (hu) Folyékony, stabil szarvasmarha-vírus vakcinák
PL2935313T3 (pl) Szczepionki przeciwko wirusowi zapalenia wątroby typu b
GB201313201D0 (en) Virus Detection
PL2969005T3 (pl) Atenuowane wirusy grypy i szczepionki
IL240025A0 (en) Influenza virus redifferentiation
SG11201510617WA (en) Methods and compositions for dengue virus vaccines
SG11201510266SA (en) Dengue virus vaccine compositions and methods of use thereof
EP2968394A4 (fr) Nouveaux vaccins contre de multiples sous-types du virus de la dengue
GB201301119D0 (en) Viral vaccines
SG11201507455WA (en) Hepatitis b virus vaccines
SG11201505170WA (en) Dengue virus vaccine composition
GB201314063D0 (en) Virus
GB201304827D0 (en) Infulenza virus reassortment
GB201306812D0 (en) Virus

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20151015

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

A4 Supplementary search report drawn up and despatched

Effective date: 20160321

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 39/295 20060101ALI20160315BHEP

Ipc: A61K 31/711 20060101AFI20160315BHEP

Ipc: A61K 39/12 20060101ALI20160315BHEP

DAX Request for extension of the european patent (deleted)
R17P Request for examination filed (corrected)

Effective date: 20151015

17Q First examination report despatched

Effective date: 20171026

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20200121