EP2996471A4 - Aminoglykosid- und azolzusammensetzungen und verfahren - Google Patents

Aminoglykosid- und azolzusammensetzungen und verfahren

Info

Publication number
EP2996471A4
EP2996471A4 EP14797052.9A EP14797052A EP2996471A4 EP 2996471 A4 EP2996471 A4 EP 2996471A4 EP 14797052 A EP14797052 A EP 14797052A EP 2996471 A4 EP2996471 A4 EP 2996471A4
Authority
EP
European Patent Office
Prior art keywords
aminoglycosides
azoles
compositions
associated methods
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14797052.9A
Other languages
English (en)
French (fr)
Other versions
EP2996471A2 (de
Inventor
Jon Takemoto
Cheng-Wei Chang
Sanjib Shrestha
Michelle Grilley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Utah State University
Original Assignee
Utah State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Utah State University filed Critical Utah State University
Publication of EP2996471A2 publication Critical patent/EP2996471A2/de
Publication of EP2996471A4 publication Critical patent/EP2996471A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EP14797052.9A 2013-05-17 2014-05-19 Aminoglykosid- und azolzusammensetzungen und verfahren Withdrawn EP2996471A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361824847P 2013-05-17 2013-05-17
PCT/US2014/038649 WO2014186804A2 (en) 2013-05-17 2014-05-19 Aminoglycoside and azole compositions and methods

Publications (2)

Publication Number Publication Date
EP2996471A2 EP2996471A2 (de) 2016-03-23
EP2996471A4 true EP2996471A4 (de) 2016-12-28

Family

ID=51899031

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14797052.9A Withdrawn EP2996471A4 (de) 2013-05-17 2014-05-19 Aminoglykosid- und azolzusammensetzungen und verfahren

Country Status (3)

Country Link
EP (1) EP2996471A4 (de)
JP (1) JP2016520086A (de)
WO (1) WO2014186804A2 (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0064830A2 (de) * 1981-04-29 1982-11-17 Pfizer Limited Pharmazeutische Präparate zur Behandlung von Nagelentzündungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020052390A1 (en) * 1997-10-22 2002-05-02 Jens Ponikau Methods and materials for treating and preventing inflammation of mucosal tissue
CN102256989B (zh) * 2008-10-03 2016-01-06 聚糖生物科学有限责任公司 糖基化细菌代谢物的阴离子轭合物
US8865665B2 (en) * 2010-12-14 2014-10-21 Utah State University Aminoglycosides: synthesis and use as antifungals

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0064830A2 (de) * 1981-04-29 1982-11-17 Pfizer Limited Pharmazeutische Präparate zur Behandlung von Nagelentzündungen

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KATHIRAVAN MUTHU K ET AL: "The biology and chemistry of antifungal agents: A review", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20, no. 19, 9 May 2012 (2012-05-09), pages 5678 - 5698, XP028939845, ISSN: 0968-0896, DOI: 10.1016/J.BMC.2012.04.045 *
SHRESTHA S ET AL: "Synergistic Activities of Azoles and K20 against Azole-resistant Candida albicans 10231", ABSTRACTS OF THE GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 113, 18 May 2013 (2013-05-18), XP009192428, ISSN: 1060-2011 *

Also Published As

Publication number Publication date
JP2016520086A (ja) 2016-07-11
EP2996471A2 (de) 2016-03-23
WO2014186804A2 (en) 2014-11-20
WO2014186804A3 (en) 2015-01-08

Similar Documents

Publication Publication Date Title
IL282202A (en) Compositions and methods for personalized neoplasia vaccines
EP2953474A4 (de) Zusammensetzungen und verfahren
EP2978300A4 (de) Zusammensetzungen und verfahren zur erhöhung einer mikrobenstabilität
EP2961831A4 (de) Zusammensetzungen und verfahren für die immuntherapie
DK3074027T3 (da) Synergistiske bakteriesammensætninger og fremgangsmåder til fremstilling og anvendelse heraf
EP3004067A4 (de) Fungizidzusammensetzungen
EP3003049A4 (de) Zusammensetzungen und verfahren zur verbesserten keimung
EP2970511A4 (de) Insulin-inkretin-konjugate
EP2964235A4 (de) Antimikrobielle antibiofilm-zusammensetzungen und verfahren zur verwendung davon
IL265876A (en) Preparations that include 15-ohepa and methods of using them
EP2889350A4 (de) Klebstoffzusammensetzung
DK3051945T3 (da) Fungicidsammensætninger
EP2958523A4 (de) Knorpelmosaikzusammensetzungen und verfahren
EP2891693A4 (de) Haftzusammensetzung
EP2930218A4 (de) Haftzusammensetzung
EP2967053A4 (de) Antimikrobielle zusammensetzungen und zugehörige verfahren zur verwendung
EP2952513A4 (de) Azolbenzolderivat
EP2977422A4 (de) Haftzusammensetzung
EP2981529A4 (de) Oridoninanaloga, zusammensetzungen damit und verfahren dafür
EP2961386A4 (de) Mirna-profilierungszusammensetzungen und verfahren zur verwendung
EP3048883C0 (de) Pestizidzusammensetzung und -verfahren
EP2964610A4 (de) Vinylsulfonbasierte 18f-labeling-zusammensetzungen sowie verfahren und verwendungen davon
EP2977420A4 (de) Haftmittelzusammensetzung
SMT202000473T1 (it) Composizione comprendente idrocortisone
DK3068428T3 (da) Annexin-ii-variant-sammensætninger og fremgangsmåder

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20151027

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RIN1 Information on inventor provided before grant (corrected)

Inventor name: TAKEMOTO, JON

Inventor name: CHANG, CHENG-WEI

Inventor name: GRILLEY, MICHELLE

Inventor name: SHRESTHA, SANJIB

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20161125

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/4174 20060101ALI20161121BHEP

Ipc: A61K 31/496 20060101ALI20161121BHEP

Ipc: A61K 31/7036 20060101AFI20161121BHEP

Ipc: A61P 31/10 20060101ALI20161121BHEP

Ipc: A61K 31/4196 20060101ALI20161121BHEP

Ipc: A61K 31/506 20060101ALI20161121BHEP

Ipc: A61K 31/4178 20060101ALI20161121BHEP

Ipc: A61K 31/415 20060101ALI20161121BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20170624