EP3039405A4 - Surface micro-texturée avec micro-miroirs intégrés pour microscopie 3d multi-échelle - Google Patents

Surface micro-texturée avec micro-miroirs intégrés pour microscopie 3d multi-échelle Download PDF

Info

Publication number
EP3039405A4
EP3039405A4 EP14841093.9A EP14841093A EP3039405A4 EP 3039405 A4 EP3039405 A4 EP 3039405A4 EP 14841093 A EP14841093 A EP 14841093A EP 3039405 A4 EP3039405 A4 EP 3039405A4
Authority
EP
European Patent Office
Prior art keywords
micro
mirrors
textured surface
integrated
scale microscopy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP14841093.9A
Other languages
German (de)
English (en)
Other versions
EP3039405B1 (fr
EP3039405A1 (fr
Inventor
Virgile Nicolas Robert VIASNOFF
Vincent Studer
Gianluca GRENCI
Remi Galland
Jean-Baptiste Sibarita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
National University of Singapore
Original Assignee
Centre National de la Recherche Scientifique CNRS
National University of Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, National University of Singapore filed Critical Centre National de la Recherche Scientifique CNRS
Publication of EP3039405A1 publication Critical patent/EP3039405A1/fr
Publication of EP3039405A4 publication Critical patent/EP3039405A4/fr
Application granted granted Critical
Publication of EP3039405B1 publication Critical patent/EP3039405B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/031—Multipass arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/02—Objectives
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/02—Objectives
    • G02B21/04—Objectives involving mirrors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/361—Optical details, e.g. image relay to the camera or image sensor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/068—Optics, miscellaneous

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Multimedia (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
EP14841093.9A 2013-08-28 2014-08-27 Surface micro-texturée avec micro-miroirs intégrés pour microscopie 3d multi-échelle Active EP3039405B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201315248A GB201315248D0 (en) 2013-08-28 2013-08-28 Imaging
PCT/SG2014/000405 WO2015030678A1 (fr) 2013-08-28 2014-08-27 Surface micro-texturée avec micro-miroirs intégrés pour microscopie 3d multi-échelle

Publications (3)

Publication Number Publication Date
EP3039405A1 EP3039405A1 (fr) 2016-07-06
EP3039405A4 true EP3039405A4 (fr) 2017-04-12
EP3039405B1 EP3039405B1 (fr) 2025-01-01

Family

ID=49355960

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14841093.9A Active EP3039405B1 (fr) 2013-08-28 2014-08-27 Surface micro-texturée avec micro-miroirs intégrés pour microscopie 3d multi-échelle

Country Status (6)

Country Link
US (1) US10668468B2 (fr)
EP (1) EP3039405B1 (fr)
JP (1) JP2016529519A (fr)
CN (1) CN105556280A (fr)
GB (1) GB201315248D0 (fr)
WO (1) WO2015030678A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013226277A1 (de) * 2013-12-17 2015-06-18 Leica Microsystems Cms Gmbh Verfahren und Vorrichtung zum Untersuchen einer Probe mittels optischer Projektionstomografie
US10600174B2 (en) 2015-12-29 2020-03-24 Test Research, Inc. Optical inspection apparatus
DE102017107733B4 (de) * 2017-04-10 2019-01-31 Leica Microsystems Cms Gmbh Lichtblattmikroskop und Nachrüstsatz hierfür
US10261302B1 (en) 2017-04-24 2019-04-16 Igor Lyuboshenko Sample holder for microscopy
US12474561B2 (en) 2017-04-24 2025-11-18 Igor Lyuboshenko Automatic correction of spherical aberration in selective plane illumination microscopy
US10768400B2 (en) 2017-04-24 2020-09-08 Igor Lyuboshenko Varying an illumination path of a selective plane illumination microscopy
US11156822B2 (en) 2017-04-24 2021-10-26 Igor Lyuboshenko Selective plane illumination microscopy with multiple illumination units scanning an object in sync with a digital camera rolling shutter
KR102429614B1 (ko) 2017-06-08 2022-08-04 삼성전자주식회사 테스트 시스템, 테스트 방법 및 이들을 이용한 반도체 장치의 제조 방법
US11141064B2 (en) * 2017-07-19 2021-10-12 Perkinelmer Health Sciences, Inc. Systems and methods for rapid wide field illumination scanning for in vivo small animal fluorescence tomographic imaging
EP3454105A1 (fr) * 2017-09-08 2019-03-13 Igor Lyuboshenko Variation d'une voie d'éclairage d'une microscopie à éclairage de plan sélectif
US10585270B2 (en) * 2017-10-25 2020-03-10 University Of Vermont And State Agricultural College Reflected image macroscopy system
EP3476797B1 (fr) * 2017-10-31 2020-02-12 Honeywell International Inc. Procédé de dépôt d'électrodes et d'électrolyte sur des capteurs électrochimiques d'un système microélectromécanique
CA3067154A1 (fr) 2018-03-29 2019-10-03 Illumina, Inc. Eclairage pour imagerie par fluorescence a l'aide d'une lentille d'objectif
US11192110B2 (en) * 2018-07-06 2021-12-07 Liu Lian Methods and systems for cell-based non-invasive prenatal testing
US11156818B2 (en) * 2018-08-13 2021-10-26 The Board Of Regents Of The University Of Texas System Flexible light sheet generation by field synthesis
CN109580485A (zh) * 2019-01-18 2019-04-05 大连理工大学 一种用于红细胞超分辨成像的固定装置和使用方法
CN109758114A (zh) * 2019-01-21 2019-05-17 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 用于角膜神经成像的光片显微镜
WO2020201147A1 (fr) * 2019-03-29 2020-10-08 Phase Holographic Imaging Phi Ab Microplaque pour microscopie
CN110208227A (zh) * 2019-05-14 2019-09-06 复旦大学 一种单物镜光片显微成像系统
KR102279335B1 (ko) * 2019-09-26 2021-07-21 한국생산기술연구원 단열 및 충격 흡수를 위한 세포 배양 용기 및 이의 제조 방법
SG10202001534WA (en) * 2020-02-20 2021-09-29 Nat Univ Singapore A cell culture plate for conducting 3d cell culture and a method of fabricating the same
WO2022026952A1 (fr) * 2020-07-31 2022-02-03 The Board Of Regents Of The University Of Texas System Systèmes et procédés d'imagerie par projection en temps réel pour la microscopie à fluorescence
EP3961192A1 (fr) * 2020-09-01 2022-03-02 Evorion Biotechnologies GmbH Dispositif, procédé et utilisation pour la détermination optique d'au moins une propriété d'un échantillon placé sur un étage d'échantillon
US12443023B2 (en) 2021-05-14 2025-10-14 Igor Lyuboshenko Light sheet microscope having streamlined field of view changes
US12411085B2 (en) * 2022-02-10 2025-09-09 ColdQuanta, Inc. Miniature atomic spectroscopy reference cell system
CN114964041B (zh) * 2022-05-18 2025-06-10 长春长光辰英生物科学仪器有限公司 孔径相关共聚焦显微测量系统及其三维重构方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050030541A1 (en) * 2003-06-30 2005-02-10 Andreas Erlbacher Device and method for analyzing samples
US20050135974A1 (en) * 2003-12-18 2005-06-23 Harvey Michael A. Device for preparing multiple assay samples using multiple array surfaces
US20070178012A1 (en) * 2005-07-19 2007-08-02 Ferrante Anthony A Side view imaging microwell array
WO2010040918A1 (fr) * 2008-10-10 2010-04-15 Centre National De La Recherche Scientifique (Cnrs) Dispositif pour la visualisation en trois dimensions en microscopie et procédé utilisant un tel dispositif
US8339704B2 (en) * 2006-11-22 2012-12-25 Vanderbilt University Photolithographed micro-mirror well for 3D tomogram imaging of individual cells

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208648A (en) * 1991-03-11 1993-05-04 International Business Machines Corporation Apparatus and a method for high numerical aperture microscopic examination of materials
US6171780B1 (en) 1997-06-02 2001-01-09 Aurora Biosciences Corporation Low fluorescence assay platforms and related methods for drug discovery
CA2272255C (fr) * 1998-05-22 2005-05-10 David R. Snelling Mesures absolues de l'intensite lumineuse dans une incandescence excitee par laser
US20030076587A1 (en) * 1998-07-30 2003-04-24 Carl Zeiss Jena Gmbh Confocal theta microscope
DE19834279C2 (de) * 1998-07-30 2002-09-26 Europ Lab Molekularbiolog Kompaktes Einzelobjektiv Theta-Mikroskop
US6875619B2 (en) * 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
WO2001071318A1 (fr) * 2000-03-21 2001-09-27 The Board Of Trustees Of The University Of Illinois Nez artificiel colorimetrique possedant un reseau de reactifs colores et procede destine a un odorat artificiel
US6563117B2 (en) * 2001-06-02 2003-05-13 Ilya Feygin Article comprising IR-reflective multi-well plates
US20040002121A1 (en) * 2001-11-06 2004-01-01 Regan Jeffrey F. High throughput methods and devices for assaying analytes in a fluid sample
JP2004069395A (ja) 2002-08-02 2004-03-04 Nec Corp マイクロチップ、マイクロチップの製造方法および成分検出方法
DE102004034957A1 (de) 2004-07-16 2006-02-02 Carl Zeiss Jena Gmbh Anordnung zur mikroskopischen Beobachtung und/oder Detektion und Verwendung
JP4832928B2 (ja) * 2006-03-14 2011-12-07 株式会社生体分子計測研究所 生体分子検査装置及び生体分子検査方法
US8143593B2 (en) 2008-10-20 2012-03-27 Brookhaven Science Associates, Llc Transmission electron microscope sample holder with optical features
WO2010059902A2 (fr) * 2008-11-24 2010-05-27 Corning Incorporated Article de culture cellulaire en 3d et procédés apparentés
US20100297675A1 (en) * 2008-11-24 2010-11-25 Huayun Deng Substrate and method for culturing breast cells
EP2826564B1 (fr) 2009-11-23 2018-12-26 3M Innovative Properties Company Articles de réseau de micropuits et procédés d'utilisation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050030541A1 (en) * 2003-06-30 2005-02-10 Andreas Erlbacher Device and method for analyzing samples
US20050135974A1 (en) * 2003-12-18 2005-06-23 Harvey Michael A. Device for preparing multiple assay samples using multiple array surfaces
US20070178012A1 (en) * 2005-07-19 2007-08-02 Ferrante Anthony A Side view imaging microwell array
US8339704B2 (en) * 2006-11-22 2012-12-25 Vanderbilt University Photolithographed micro-mirror well for 3D tomogram imaging of individual cells
WO2010040918A1 (fr) * 2008-10-10 2010-04-15 Centre National De La Recherche Scientifique (Cnrs) Dispositif pour la visualisation en trois dimensions en microscopie et procédé utilisant un tel dispositif

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2015030678A1 *

Also Published As

Publication number Publication date
JP2016529519A (ja) 2016-09-23
US20160214107A1 (en) 2016-07-28
EP3039405B1 (fr) 2025-01-01
WO2015030678A1 (fr) 2015-03-05
EP3039405A1 (fr) 2016-07-06
CN105556280A (zh) 2016-05-04
GB201315248D0 (en) 2013-10-09
US10668468B2 (en) 2020-06-02

Similar Documents

Publication Publication Date Title
EP3055728A4 (fr) Microscopie à feuille de lumière à multivues
EP3065622A4 (fr) Cartographie de la surface oculaire
EP3030303B8 (fr) Interface
EP3038933B8 (fr) Carton avec élément de verrouillage
EP2976205A4 (fr) Impression tridimensionnelle
EP3010394A4 (fr) Système à réfractomètre à oct intégrés de biométrie oculaire
EP3067389A4 (fr) Composition polymère pour imprimante 3d
EP3061059A4 (fr) Création d'offre mobile
EP3033677A4 (fr) Techniques de traitement de demandes
EP3014394A4 (fr) Interface complète corps humain-ordinateur
EP3047363A4 (fr) Approches concernant l'affichage tridimensionnel d'objets
EP2951756A4 (fr) Techniques de recherche à base d'image utilisant des commandes tactiles
EP3027249A4 (fr) Stylo d'injection
GB2515627B (en) Stereoscopic microscope
EP3019557A4 (fr) Composés polyester ayant des propriétés de surface hydrophobes améliorées
EP3055794A4 (fr) Archivage hiérarchique de données
EP2960568A4 (fr) Dispositif émetteur de lumière en surface
EP3013529A4 (fr) Article abrasif
SG11201510073UA (en) Surface modification
EP3094512A4 (fr) Véhicule de surface
EP3036064A4 (fr) Article abrasif
EP3066047A4 (fr) Objet en graphite
EP2987074A4 (fr) Pré-gonflage d'objet ajusté par application
EP3078997A4 (fr) Dispositif photonique intégré
EP3055271A4 (fr) Article réfractaire

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20160229

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RIN1 Information on inventor provided before grant (corrected)

Inventor name: VIASNOFF, VIRGILE NICOLAS ROBERT

Inventor name: STUDER, VINCENT

Inventor name: SIBARITA, JEAN-BAPTISTE

Inventor name: GALLAND, REMI

Inventor name: GRENCI, GIANLUCA

DAX Request for extension of the european patent (deleted)
RIN1 Information on inventor provided before grant (corrected)

Inventor name: VIASNOFF, VIRGILE NICOLAS ROBERT

Inventor name: SIBARITA, JEAN-BAPTISTE

Inventor name: GALLAND, REMI

Inventor name: STUDER, VINCENT

Inventor name: GRENCI, GIANLUCA

A4 Supplementary search report drawn up and despatched

Effective date: 20170313

RIC1 Information provided on ipc code assigned before grant

Ipc: G02B 21/16 20060101ALI20170307BHEP

Ipc: G02B 21/36 20060101ALI20170307BHEP

Ipc: B01L 3/00 20060101ALI20170307BHEP

Ipc: G02B 21/06 20060101ALI20170307BHEP

Ipc: G02B 21/00 20060101ALI20170307BHEP

Ipc: G01N 21/03 20060101AFI20170307BHEP

Ipc: G02B 21/02 20060101ALI20170307BHEP

Ipc: G01N 21/64 20060101ALI20170307BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20190313

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Free format text: PREVIOUS MAIN CLASS: G01N0021030000

Ipc: G02B0021340000

Ref country code: DE

Ref legal event code: R079

Ref document number: 602014091409

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: G01N0021030000

Ipc: G02B0021340000

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

RIC1 Information provided on ipc code assigned before grant

Ipc: G02B 21/00 20060101ALI20240709BHEP

Ipc: G02B 21/06 20060101ALI20240709BHEP

Ipc: G01N 21/64 20060101ALI20240709BHEP

Ipc: G01N 21/00 20060101ALI20240709BHEP

Ipc: G01N 21/03 20060101ALI20240709BHEP

Ipc: B01L 3/00 20060101ALI20240709BHEP

Ipc: G02B 21/34 20060101AFI20240709BHEP

INTG Intention to grant announced

Effective date: 20240731

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

P01 Opt-out of the competence of the unified patent court (upc) registered

Free format text: CASE NUMBER: APP_61719/2024

Effective date: 20241119

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602014091409

Country of ref document: DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG9D

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1756829

Country of ref document: AT

Kind code of ref document: T

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250501

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250401

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250502

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250402

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20250827

Year of fee payment: 12

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602014091409

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20250929

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20250825

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20250827

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20250827

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20250919

Year of fee payment: 12

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20251002

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20250101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20250827