EP3126027A4 - Vorrichtungen und verfahren zur reinigung, detektion und verwendung biologischer zellen - Google Patents

Vorrichtungen und verfahren zur reinigung, detektion und verwendung biologischer zellen Download PDF

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Publication number
EP3126027A4
EP3126027A4 EP15773853.5A EP15773853A EP3126027A4 EP 3126027 A4 EP3126027 A4 EP 3126027A4 EP 15773853 A EP15773853 A EP 15773853A EP 3126027 A4 EP3126027 A4 EP 3126027A4
Authority
EP
European Patent Office
Prior art keywords
purification
detection
methods
devices
biological cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15773853.5A
Other languages
English (en)
French (fr)
Other versions
EP3126027A1 (de
Inventor
Douglas T. Gjerde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP3126027A1 publication Critical patent/EP3126027A1/de
Publication of EP3126027A4 publication Critical patent/EP3126027A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/428—Frontal mode
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/166—Fluid composition conditioning, e.g. gradient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422—Displacement mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP15773853.5A 2014-04-03 2015-04-03 Vorrichtungen und verfahren zur reinigung, detektion und verwendung biologischer zellen Withdrawn EP3126027A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461974950P 2014-04-03 2014-04-03
US201462061636P 2014-10-08 2014-10-08
PCT/US2015/024374 WO2015154048A1 (en) 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells

Publications (2)

Publication Number Publication Date
EP3126027A1 EP3126027A1 (de) 2017-02-08
EP3126027A4 true EP3126027A4 (de) 2017-11-01

Family

ID=54241352

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15773853.5A Withdrawn EP3126027A4 (de) 2014-04-03 2015-04-03 Vorrichtungen und verfahren zur reinigung, detektion und verwendung biologischer zellen

Country Status (3)

Country Link
EP (1) EP3126027A4 (de)
GB (2) GB2587768B (de)
WO (1) WO2015154048A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201521784D0 (en) * 2015-12-10 2016-01-27 Univ Birmingham Cell purification
WO2020076818A1 (en) * 2018-10-09 2020-04-16 C Technologies, Inc. Mass control system for chromatography
GB2616583B (en) * 2020-12-21 2025-08-13 T Gjerde Douglas Piston Pump Syringe Column Method and Device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773224A (en) * 1996-02-12 1998-06-30 Grandics; Peter Immunoselection system for cell elution
WO2014127314A1 (en) * 2013-02-15 2014-08-21 Phynexus, Inc. Devices and methods for purification of biological cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215927A (en) * 1986-01-30 1993-06-01 Fred Hutchinson Cancer Research Center Method for immunoselection of cells using avidin and biotin
WO1999032886A1 (en) * 1997-12-23 1999-07-01 Vicam, L.P. Generic signalling mechanism for detection of analytes
EP1573061A4 (de) * 2002-12-18 2006-03-08 Aclara Biosciences Inc Immunhistochemische multiplex-assays mit molekularen tags
US20090081084A1 (en) * 2003-07-14 2009-03-26 Gjerde Douglas T Low Dead Volume Extraction Column Device
US8377715B2 (en) * 2003-07-14 2013-02-19 Phynexus, Inc. Method and device for sample preparation
US20100140173A1 (en) * 2004-12-03 2010-06-10 Chris Suh Method and Device for Gravity Flow Chromatography
US9370732B2 (en) * 2013-02-15 2016-06-21 Douglas T. Gjerde Methods for purifying biological cells
ES3011307T3 (en) * 2012-02-23 2025-04-07 Juno Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
WO2014001326A1 (en) * 2012-06-27 2014-01-03 F. Hoffmann-La Roche Ag Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773224A (en) * 1996-02-12 1998-06-30 Grandics; Peter Immunoselection system for cell elution
WO2014127314A1 (en) * 2013-02-15 2014-08-21 Phynexus, Inc. Devices and methods for purification of biological cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LI CUIQIN ET AL: "Establishment of the model of white blood cell membrane chromatography and screening of antagonizing TLR4receptor component fromAtractylodes macrocephalaKoidz", SCIENCE IN CHINA. SERIE C: LIFE SCIENCE, GORDON AND BREACH, AMSTERDAM, NL, vol. 49, no. 2, 25 March 2006 (2006-03-25), pages 182 - 189, XP035977382, ISSN: 1006-9305, [retrieved on 20060325], DOI: 10.1007/S11427-006-0182-7 *
See also references of WO2015154048A1 *

Also Published As

Publication number Publication date
GB201618356D0 (en) 2016-12-14
GB2587768A (en) 2021-04-07
EP3126027A1 (de) 2017-02-08
GB2539857B (en) 2021-03-31
GB2587768B (en) 2021-08-18
GB2539857A (en) 2016-12-28
WO2015154048A1 (en) 2015-10-08
GB202102155D0 (en) 2021-03-31

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