EP3204813B2 - Microscope avec diaphragme à iris à adaptation automatique - Google Patents

Microscope avec diaphragme à iris à adaptation automatique Download PDF

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Publication number
EP3204813B2
EP3204813B2 EP15771603.6A EP15771603A EP3204813B2 EP 3204813 B2 EP3204813 B2 EP 3204813B2 EP 15771603 A EP15771603 A EP 15771603A EP 3204813 B2 EP3204813 B2 EP 3204813B2
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EP
European Patent Office
Prior art keywords
microscope
zoom
setting
stop
control unit
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EP15771603.6A
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German (de)
English (en)
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EP3204813B1 (fr
EP3204813A1 (fr
Inventor
Harald Schnitzler
Georg Schlaffer
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Leica Microsystems Schweiz AG
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Leica Microsystems Schweiz AG
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/02—Objectives
    • G02B21/025—Objectives with variable magnification
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing

Definitions

  • the invention relates to a microscope that includes an objective system that has at least two objectives that can be selectively introduced into the beam path and have different focal lengths. Furthermore, the microscope has a zoom system that has a zoom range, with the respective total magnification of an object to be examined being obtained from the focal length of the selected lens and the focal length of the zoom system set within the zoom range. Furthermore, the microscope has a diaphragm for limiting the aperture of the beam path, with the size of the opening of the diaphragm and thus the aperture being adjustable by adjusting the diaphragm.
  • Known microscopes have objective systems and/or zoom systems, with the help of which the focal length and thus the overall magnification of the image of an object to be examined under the microscope can be adjusted.
  • a different ideal setting of the microscope aperture is necessary in order to achieve optimal images.
  • An iris diaphragm is therefore provided for setting the aperture, in which the size of the opening can be adjusted, as a result of which the aperture is changed accordingly.
  • Microscopes are known in which the aperture is set manually using appropriate actuating elements.
  • microscopes are known in which the diaphragm is adjusted by a motor. What both variants have in common is that the user of the microscope has to adjust the diaphragms according to the respectively selected settings of the microscope and that the diaphragm is not adjusted without a corresponding actuation by the user.
  • microscopes are known in which an iris diaphragm is provided, which is mechanically coupled to the zoom system in such a way that the diaphragm is also automatically adjusted as a function of the zoom position set.
  • document DE 10 2009 012 707 A1 discloses a microscope with a zoom objective, a pancratic zoom system, a zoom tube system, an aperture stop with a variable stop opening and a control unit.
  • the three zoom systems form an optical system with a magnification that results from the product of the individual magnifications of the three zoom systems.
  • the control unit is designed to control functional parameters of the aforementioned optical elements. Functional parameters are in particular the imaging scale of the zoom systems and the aperture of the diaphragm.
  • the microscope also includes a changer for lenses with different fixed focal lengths.
  • document DE 10 2010 045 860 A1 discloses a zoom system for a microscope that includes a diaphragm with a variable diaphragm opening, the object-side aperture of which increases non-linearly in relation to the magnification.
  • document JP H09 21957 A revealed in the figures 1 and 2 a microscope with an objective turret 9 for pivoting at least two objectives 8a, 8b into an observation beam path of the microscope, an aperture stop and an aperture control unit.
  • the diaphragm opening of the aperture diaphragm is selected by the aperture control unit as a function of the focal length and the magnification of the lens pivoted into the observation beam path of the microscope.
  • a control unit for controlling the aperture is provided, with the aid of which the optimal setting of the aperture is automatically determined in each case and the aperture is set accordingly.
  • the control unit automatically determines, depending on the current characteristic of at least one parameter of the microscope, an ideal aperture setting for the current characteristic and sets the aperture accordingly. This ensures that the optimal setting of the aperture is automated in each case and thus the aperture of the microscope is set and the operator does not have to laboriously determine and set the ideal setting of the aperture himself when changing the execution of a parameter of the microscope. This increases the ease of use, reduces the training period and the necessary expert knowledge of the user, and operating errors are avoided.
  • the current characteristic is the current value or the current setting of the parameter.
  • the parameter is, for example, one or more parameters from the following group, which includes at least: setting of the zoom system, lens used and/or current user setting.
  • a motor for adjusting the diaphragm can be provided, with the control unit automatically controlling the motor in such a way that it adjusts the diaphragm accordingly.
  • the size of the opening of the aperture can be controlled very precisely and accurately by the motorization and the automatic control as a function of at least one parameter of the microscope.
  • the ideal aperture can thus be set in a simple manner for every possible setting of the microscope.
  • a so-called "digital fusion optics” is thereby possible, in which images of an object with different aperture and thus resolution are recorded in quick succession and superimposed to form an image.
  • a scanning takes place to determine the "better” areas of the images in each case, which are then combined to form a master image.
  • the diaphragm is in particular an iris diaphragm in which the size of its opening can be varied in a simple manner.
  • iris diaphragms have a simple and robust design and allow the aperture to be set precisely in a simple manner.
  • an aperture limiter with a large number of electronically controllable segments can also be provided as the diaphragm.
  • the transmissivity or the reflectivity of each segment of the electronically controllable segments can be individually controllable.
  • the aperture stop is a liquid crystal matrix with a two-dimensional grid of LCD segments.
  • the aperture stop is therefore also referred to as an "LC shutter”.
  • control unit determines the predetermined, ideal setting of the diaphragm as a function of the current characteristics of at least two parameters of the microscope and controls the motor in such a way that it sets the diaphragm accordingly.
  • more than two parameters can also be automatically taken into account when determining the ideal setting of the diaphragm.
  • all parameters of the microscope that can be adjusted by the operator are taken into account, so that the operator never has to change the setting of the diaphragm himself, depending on which settings he makes, in order to obtain a high-quality image.
  • the settings of the aperture to be set have in particular been previously determined experimentally and/or by calculation and selected in such a way that they result in a high-quality image of the object to be examined under the microscope, in particular the image optimally adapted to the respective setting.
  • the aperture setting to be set is stored in the control unit for all possible forms of the parameters taken into account and also for all possible combinations of the forms of the parameters, clearly assigned to the respective forms.
  • the control unit When determining the setting of the diaphragm to be set, the control unit then reads out the corresponding setting value of the diaphragm as a function of the current expression of the parameter to be taken into account and controls the motor accordingly.
  • a table is stored in the control unit, in which the correspondingly set values of the aperture are stored for all possible forms and their combination.
  • a calculation rule can also be stored in the control unit, with the control unit using this calculation rule determining the aperture setting to be set in each case.
  • the parameters whose characteristics are to be taken into account are contained in this calculation rule, so that the required ideal setting of the aperture is obtained as a result of the calculation rule, depending on the characteristics of the respective parameters.
  • the calculation rule has been determined beforehand, in particular with the aid of simulations and compensation functions.
  • the settings to be set for the diaphragm are in particular selected in such a way that they are the optimal setting of the diaphragm for the respective characteristic of the parameters or their combination, i.e. that the optimum aperture results for the selected characteristics of the parameters.
  • the settings of the diaphragm to be set can be stored directly as the necessary setting parameters of the diaphragm, necessary control data for the motor, aperture to be set and/or size of the opening of the diaphragm to be set. These values can be converted into one another as desired, so that it is irrelevant how they are stored.
  • control unit determines the aperture setting to be set as a function of the current setting of the zoom system and sets the aperture automatically accordingly.
  • the parameter taken into account when setting the diaphragm is the zoom setting and the current characteristic is the current setting of the zoom system.
  • the advantage is achieved that the system has a much simpler structure.
  • the automatic electrical setting of the respective aperture setting enables other parameters to be taken into account in addition to the zoom setting.
  • the lens currently placed in the beam path is additionally or alternatively taken into account when determining the setting of the diaphragm.
  • the lens currently placed in the beam path is additionally or alternatively taken into account when determining the setting of the diaphragm.
  • there is a different ideal aperture so that the aperture must be adjusted accordingly, which is easily achieved by considering the selected lens as a parameter when determining the aperture setting.
  • control unit determines the aperture setting to be set as a function of at least one property of at least one hardware component of the microscope. This achieves an even better adaptation of the aperture of the microscope to the setting used in each case.
  • various hardware components of the microscope for example the image sensor used, can be changed, resulting in other ideal apertures due to the different resolutions and sensitivities of the image sensor.
  • the control unit determines the aperture setting to be set, in particular as a function of the resolution of an image sensor of the microscope, the sensitivity of an image sensor of a microscope, the resolution of a camera of the microscope and the sensitivity of a camera of the microscope.
  • the control unit determines the setting of the aperture to be set as a function of at least one user setting of a user of the microscope.
  • the microscope is designed in such a way that the user can select preferences and settings. These user settings can be, for example, the desired exposure time, a desired one of several resolution levels, a desired one of several predetermined depths of field or a desired one of several predetermined brightness levels.
  • the automatic adjustment ensures that the user does not have to laboriously convert his preferences into the necessary aperture settings, but rather he can select the desired preferences via a menu in plain text and the microscope carries out all the necessary settings automatically.
  • a selection menu can be specified via a computer connected to the microscope, in which the user can select "constant brightness”, “extended resolution”, “better resolution”, “greater depth of field” etc. as a preference, for example.
  • the aperture setting must be changed accordingly, which is done automatically by the control unit.
  • the aforementioned parameters ie in particular the zoom setting, the lens used, properties of hardware components and/or the user settings, are taken into account when determining the aperture setting and automatically implementing this setting.
  • the aperture setting is electronically controlled. With a mechanical setting of the aperture, only one parameter can be aimed at, whereas the automatic setting via the control unit, i.e. the firmware of the microscope, allows any number of parameters to be taken into account in any combination.
  • At least one sensor unit is provided for determining the current characteristic of the parameter or the current characteristics of the parameters. This is particularly necessary when one of the parameters can be set manually so that the control unit knows which setting is currently being made. For example, in the microscope, the lens system can be adjusted manually and purely mechanically, so that initially there is no electronic information about the respective setting. In this case, sensors are provided in particular, with the help of which the setting can be clearly determined.
  • a partial zoom range within the zoom range is assigned to each of the lenses, with limiting means being provided by which the adjustability of the zoom system is limited to the zoom range that is assigned to the selected lens.
  • the control unit determines the predetermined setting of the aperture as a function of the respectively selected objective and/or the set one Focal length of the zoom system.
  • the focal length differences of the lenses used do not have to be as large as with conventional microscopes.
  • the zoom system also achieves the highest possible magnification, and this thus works together for a high overall magnification.
  • the partial zoom range is selected within the overall zoom range in such a way that it also corresponds to a lower magnification, so that large field angles are achieved.
  • the associated partial zoom range means that the zoom system is adapted to the individual requirements of the respective objective, so that less stringent requirements can be placed on the construction of the objective and, in particular, objectives with focal lengths that are closer together can be used.
  • lenses with more similar dimensions can thus be used, which in particular enables a parfocal lens system.
  • Such a parfocal design of the objective system means that no new focusing is required when the objective is changed.
  • the overall zoom range of the zoom system is understood to mean, in particular, the structurally conditioned maximum available zoom range.
  • the total zoom range indicates in particular the various focal lengths that can be set using the zoom system.
  • the limits of the overall zoom range are thus given by a minimum focal length and a maximum focal length of the zoom system.
  • the objective system comprises, in particular, an objective turret in which the various objectives are mounted and by rotating which the desired objective can be introduced into the beam path.
  • the lenses themselves are in particular designed in such a way that the arrangement of the individual lens groups relative to one another is fixed and cannot be adjusted.
  • the zoom system has a plurality of lens groups, at least one of which can be moved axially relative to the stationary lens groups, as a result of which the focal length of the zoom system and thus its magnification can be adjusted.
  • a second partial zoom range within the overall zoom range is preferably also assigned to the second lens.
  • the partial zoom range of at least one lens is smaller than the total zoom range. It is particularly advantageous if the partial zoom ranges of all lenses are each smaller than the overall zoom range of the zoom system. Thus, for each lens, only that part of the total zoom range is used that matches the properties of the lens in terms of its properties.
  • the zoom system is also referred to as an "oversized” or “oversized” zoom system.
  • the partial zoom ranges of the lenses can also overlap at least partially. Alternatively, it is also possible for the partial zoom areas to be selected in such a way that there is no overlapping.
  • the overlapping of the partial zoom ranges ensures that each lens has the largest possible adjustment range by setting the focal length of the zoom system accordingly and the magnification can be varied accordingly.
  • the lower and upper limits of the partial zoom ranges are each selected in such a way that the same predetermined zoom factor results in the various partial zoom ranges between the respective lower and upper limits.
  • the zoom factor means in particular the quotient of the upper and lower limits, ie in particular the quotient of the maximum focal length and the minimum focal length, for the respective partial zoom range. This ensures that the same zoom factor is available to the operator for each lens, so that the operator has the same magnification options regardless of which lens is used, although the overall magnifications will of course vary depending on the lens used, since this is The quotient of the focal length of the zoom system by the focal length of the lens.
  • the lower limit of at least one partial zoom range corresponds to the lower limit of the total zoom range and the upper limit of at least one partial zoom range corresponds to the upper limit of the total zoom range.
  • the partial zoom ranges are preset in such a way that the partial zoom range of a lens with a focal length that is greater than the focal length of another lens includes magnifications or focal lengths that are smaller than the smallest magnification or focal length of the partial zoom range of this other lens.
  • the zoom sub-area is thus selected in such a way that it covers the smaller focal lengths of the zoom sub-area in relation to the entire zoom range, so that the properties of the lens and the zoom system, in particular the desired large field angle at low magnifications, complement each other optimally.
  • the zoom sub-ranges are preset such that the zoom sub-range of a lens with a focal length that is smaller than the focal length of another lens includes magnifications or focal lengths that are greater than the largest magnification or focal length of the zoom sub-range of another lens.
  • the partial zoom range also covers the long focal lengths of the overall zoom range and thus contributes to a large overall magnification.
  • the lens system has a first lens with a first focal length and a second lens with a second focal length, the second focal length being greater than the first focal length.
  • the second objective causes a lower magnification than the first objective.
  • the overall zoom range has a third focal length as the lower limit and a fourth focal length as the upper limit.
  • the upper limit of the first partial zoom area assigned to the first lens is the fourth focal length and the lower limit of the second partial zoom area assigned to the second lens is the third focal length. It is thus achieved that the first lens, which has the higher magnification of the two lenses, achieves a maximum overall magnification when setting the fourth focal length together with the zoom system. Conversely, the lowest possible magnification can be achieved by selecting the second lens and the third focal length.
  • the focal lengths can also be selected in such a way that, with appropriate settings, the overall magnifications are ⁇ 1, i. This means that the objects are shown reduced.
  • Limiting means are provided, by means of which the adjustability of the zoom system is limited in each case to the partial zoom range that is assigned to the selected lens, ie to the lens that is currently inserted in the beam path.
  • At least one stop is provided as a limiting means on each objective, the adjustability of the zoom system being limited to the partial zoom range assigned to this objective by the stop. In this way, it is purely mechanically ensured that, with each lens, the zoom system can only be adjusted within the assigned partial zoom range.
  • two stops are provided on each lens, by which the adjustment of the zoom system is limited. If a limit of the partial zoom range is given by a limit of the maximum possible overall zoom range due to construction, a stop on this side can be dispensed with.
  • the zoom system can also be adjusted electrically by providing an electric drive unit, in particular a motor.
  • a control unit for controlling the drive unit is provided, with the partial areas assigned to the respective lenses being stored in this control unit. The control unit then controls the drive unit in such a way that only one adjustment within the respective partial zoom range is possible.
  • a sensor system is provided through which the control unit can automatically recognize which lens is placed in the beam path, so that the control unit then automatically selects the partial zoom range that can be set by the operator and controls the electric drive unit accordingly.
  • the microscope includes an actuating element for manually setting the magnification factor of the zoom system.
  • This actuating element can be a rotary knob.
  • the zoom system has at least two lens groups, one of which can be moved in the direction of the optical axis in order to set the focal length of the zoom system.
  • the zoom system has three or four lens groups, two of which can be moved in the direction of the optical axis.
  • the microscope is, in particular, a digital microscope that includes an image acquisition unit for acquiring images of the object to be examined under the microscope.
  • the image of the object to be examined under the microscope is imaged directly onto the image acquisition unit, in particular via the zoom system.
  • An alternative embodiment can also be visual microscopes.
  • FIG 1 a schematic perspective representation of a digital microscope is shown.
  • the microscope 10 comprises a stationary stand base body 12 and a pivoting unit 14 that can be pivoted relative to it.
  • the pivoting unit 14 includes at least one image acquisition unit, with the aid of which an image of the objects to be examined under the microscope can be recorded.
  • image acquisition unit with the aid of which an image of the objects to be examined under the microscope can be recorded.
  • image series and videos can be recorded via this image acquisition unit, which make it possible to view the object to be examined under the microscope from different angles.
  • the pivoting unit has a lens and a zoom system, with the help of which different magnifications of the objects to be examined under the microscope can be set.
  • the lens system has a large number of lenses, one of which is selectively introduced into the beam path.
  • the image capture unit, lens system and zoom system are in figure 1 not visible because they are covered by the housing 16 of the swivel unit 14.
  • the lenses of the lens system are in particular designed to be parfocal, so that the operator does not have to refocus when changing the lens.
  • the lenses are matched in particular to the distance between the axis of rotation, through which the pivot axis 14 can be rotated, and the interface of the lenses, so that a eucentric system results, which means that when the pivot unit 14 is pivoted, there is no new focusing must take place and the observed area remains centered in the middle of the image.
  • an object table 18 is arranged on the stand base body, on which the objects to be examined under the microscope are placed.
  • This object table 18 can be adjusted relative to the stand base body 12 in the direction of the double arrow P1 with the aid of adjusting wheels 20, as a result of which it is possible to focus the objects to be examined under the microscope.
  • magnification system arranged in the pivoting unit 14 is shown purely schematically in three different settings.
  • the magnification system includes an objective system 30 and a zoom system 32, through the interaction of which a desired overall magnification is achieved.
  • the lens system 30 includes at least two lenses 44, 52 with different focal lengths, one of which is selectively swiveled into the beam path of the microscope 10.
  • the zoom system 32 has three lens groups 34 to 38, of which two lens groups 36, 38 can be adjusted in the direction of the optical axis 50.
  • the zoom system can also include only two lens groups 34 to 38, of which only one lens group 34 to 38 is axially adjustable.
  • zoom systems with more than three lens groups 34 to 38 are also conceivable.
  • the image of the object is imaged via the zoom system 32 directly on an image acquisition unit 40, which can in particular be a camera.
  • FIG 2 three settings of the zoom system 32 are shown.
  • the zoom system 32 is set to have maximum focal length and thus provide maximum magnification.
  • the field angle 42 which indicates the angle of the principal ray to the optical axis 50 in the area of the interface to the objective system 30, is minimal.
  • the right-hand setting shows the other extreme setting of the zoom system 32, namely that setting in which the zoom system 32 has a minimum focal length and correspondingly has a minimum magnifying effect.
  • the field angle 42 is at its maximum.
  • the middle case shown represents an intermediate position in which a focal length is achieved by the zoom system 32 which is greater than the minimum focal length and less than the maximum focal length.
  • the field angle 42 lies between the field angles 42 of the other two cases.
  • the respective total magnification of the microscope 10 results from the quotient of the set focal length of the zoom system 32 and the focal length of the lens 44, 52 of the lens system 30 introduced into the beam path.
  • the zoom system 32 has an overall zoom range that specifies the focal lengths of the zoom system 32 that can be set via the zoom system 32 .
  • This total zoom range is in figure 5 exemplified by the arrow 90, the lower limit 92 indicates the minimum focal length of the zoom system 32, which is at the in figure 2 setting shown on the right.
  • the upper limit 94 of the overall zoom range 90 accordingly indicates the maximum focal length of the zoom system 32, which is at the figure 2 setting shown on the left.
  • the total zoom range 90 is thus predetermined in particular due to the type of construction and indicates the maximum possible range of magnifications of the zoom system 32 .
  • the lens system 32 includes a plurality of lenses 44, 52 with different focal lengths.
  • Each of these lenses 44, 52 is assigned a partial zoom range within the overall zoom range 90, with figure 5 a first partial zoom area 96 for a first lens 44 and a second partial zoom area 98 of a second lens 52 are shown.
  • the two partial zoom areas 96, 98 each cover only part of the overall zoom area 90 and are in particular designed in such a way that they at least partially overlap.
  • the microscope 10 is designed in such a way that the zoom system 32 can only ever be adjusted within the partial zoom range 96, 98 which is assigned to the objective 44, 52 currently pivoted into the beam path.
  • the first lens 44 to which the partial zoom area 96 is assigned, has a greater focal length compared to the second lens 52 and thus has a lower magnifying effect.
  • the first partial zoom area 96 is correspondingly also selected in such a way that it covers the smaller magnifications of the overall zoom area 90 compared to the second partial zoom area 98 , whereas the second partial zoom area 98 includes the higher enlargements of the overall zoom area 90 .
  • a partial zoom range 96 is assigned in which the zoom system 32 also has a low magnification and thus a large field angle.
  • the sub-area of the zoom system 32 used is always matched to the properties of the respective lens 44, 52.
  • FIG 3 12 is a schematic representation of the magnification system of FIG figure 2 shown in two states, with the first objective 44 of the objective system 30 being introduced into the beam path.
  • the adjustability of the zoom system 32 is limited by limiting elements 46, 48 in such a way that, compared to the maximum adjustment range in figure 2 is shown, although an adjustment to the minimum focal length ( figure 3 , right), but not possible up to the maximum focal length. Accordingly, the zoom system 32 can only be adjusted within the first partial zoom area 96 .
  • the limiting elements 46, 48 prevent the lens groups 36, 38 from moving towards one another on the in figure 3 , limited condition shown left.
  • the limiting elements 46, 48 are stops that are coupled to the first objective 44, so that when the first objective 44 is introduced into the beam path, the stops 46, 48 are automatically moved as well, so that they are arranged in such a way that they are arranged in the range of movement of the lens groups 34-38.
  • FIG 4 the case is shown in which the second lens 52 is pivoted into the beam path.
  • This lens 52 again includes stops 54, 56, by which the adjustment of the zoom system 32 is limited to the second partial zoom range 98.
  • the stops 54, 56 prevent the lens groups 36, 38 from being positioned further than in the case of the figure 4 , state shown on the right are moved away from each other so that setting of the minimum magnification is prevented.
  • zoom sub-areas 96, 98 in which the zoom system 32 is operated are thus shown to be smaller than the maximum overall zoom area 90, which is why the zoom system 32 is also referred to as an "oversized" zoom system.
  • an embodiment is shown in which an aperture stop 60 is provided for setting the aperture, which is designed in particular in the form of an iris stop.
  • an iris diaphragm instead of an iris diaphragm, other types of diaphragms can also be used, which allow the size of their opening and thus the aperture to be changed.
  • a system of diaphragms can also be provided that includes a plurality of diaphragms with different opening sizes, which can be introduced into the beam path depending on the required aperture.
  • an electric drive unit 62 in particular a motor, is provided, with the aid of which the diaphragm 60 can be adjusted, i.e. with the aid of which the size of the diaphragm 60 can be adjusted.
  • the microscope 10 comprises a control unit 64 which controls the motor 62 and which, via its control signals, specifies to the motor 62 which setting of the aperture 60 it should set.
  • the control unit 64 is designed in such a way that, depending on the current version or setting of the zoom system 32 and the currently introduced into the beam path of the microscope and thus used objective 44, 54 determines the setting of the diaphragm 60 to be set, which is necessary to achieve the ideal aperture.
  • control unit 64 which contains the necessary setting of the diaphragm 60 for each possible zoom setting and each possible lens or the combinations resulting therefrom.
  • control unit 64 reads out the necessary setting of the aperture 60 from this assignment specification and accordingly controls the motor 62 in such a way that it sets the aperture 60 according to the preset setting.
  • a calculation rule can also be stored in control unit 64, with the help of which control unit 64 calculates the respective ideal setting of the Aperture 60 determined.
  • the microscope 10 includes, in particular, a first sensor 66, with the aid of which the current characteristics or setting of the zoom system 32 can be determined.
  • the determined current setting is transmitted in particular to the control unit 64 so that it knows at all times how the zoom system 32 is set and can thus adjust the diaphragm 60 ideally in each case.
  • the first sensor 66 can be a Hall sensor, for example, which can be used to determine the rotational position of the spindle for adjusting the lens groups 34 to 38 of the zoom system 32 and thus the characteristics of the zoom system 32 .
  • a second sensor 68 is provided in particular, with the help of which the characteristic of the objective system 30 can be determined, i.e. which of the objectives 44, 52 of the objective system 30 is currently introduced into the beam path.
  • This information is also transmitted to the control unit 64 so that it can automatically adjust the setting of the diaphragm 60 when the lens 44, 52 is changed.
  • each objective 44, 52 has a contact, with the contact of the objective 44, 52, which is introduced into the beam path, being in contact with a contact of the sensor 68, so that the sensor can easily determine which objective 44, 52 is currently introduced into the beam path.
  • the sensors 66 and 68 are necessary in particular when the zoom system 32 or the lens system 30 is adjusted purely mechanically and manually, since in this case there is no electronic data with information about the current settings. If, on the other hand, the zoom system 32 and the lens system 30 are adjusted with the aid of electronically controlled units, the control signals used for this purpose can be used by the control unit 64 to determine the setting of the zoom system 32 or the lens system 30, so that no sensors 66, 68 are necessary.
  • control unit 64 can also only take into account the setting of the zoom system 32 or only the setting of the lens system 30 when determining the setting of the diaphragm 60 .
  • control unit 64 it is alternatively possible for the control unit 64 to also take other parameters into account when automatically setting the diaphragm 60 .
  • properties of components of the microscope 10 can be taken into account.
  • the resolution and/or the sensitivity of the image acquisition unit 40 can also be taken into account by the control unit 64 . This is particularly useful when individual components can be changed, for example because they are external components.
  • user preferences and user settings can be used as additional parameters as a function of which the control unit 64 determines the setting of the diaphragm 60 to be set.
  • the operator can select various preferences or settings in plain text on a computer connected to the microscope 10 .
  • an operator may indicate that they want constant brightness or enhanced resolution.
  • the operator can select “better resolution” or “greater depth of field” via a menu item, for example.
  • control unit 64 automatically taking into account these preferences and settings selected in plain text when determining the necessary setting of the aperture 60 and automatically setting the aperture 60 so that the user does not have to correspondingly does not have to adjust the aperture himself experimentally according to his preferences, but everything is done automatically by the control unit 64.
  • a liquid crystal matrix with a two-dimensional grid of LCD segments can also be used instead of the iris diaphragm (60).
  • the motor (62) can be omitted.
  • the control unit (64) controls the liquid crystal matrix directly and activates or deactivates the LCD segments accordingly.

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Lenses (AREA)
  • Exposure Control For Cameras (AREA)
  • Lens Barrels (AREA)

Claims (15)

  1. Microscope comprenant
    un système d'objectif (30) comportant au moins deux objectifs (44, 52) pouvant être introduits sélectivement sur le chemin optique et ayant des distances focales différentes,
    un système de zoom (32) ayant une plage de zoom totale (90), dans lequel le grossissement total respectif d'un objet à examiner au microscope résulte respectivement de la distance focale de l'objectif sélectionné (44, 52) et du grossissement du système de zoom (32) réglé dans à l'intérieur de la plage de zoom totale (90),
    un diaphragme (60) destiné à limiter l'ouverture du chemin optique,
    une unité de commande (64) destinée à commander l'ouverture (60),
    caractérisé en ce que
    des plages de zoom partielles (96, 98) à l'intérieur de la plage de zoom totale (90) sont associées aux objectifs (44, 52), dans lequel la plage de zoom partielle associée de chacun des objectifs (44, 52) est plus petite que la plage de zoom totale du système de zoom (32), en ce qu'il est prévu des moyens de limitation (46, 48, 54, 56) à l'aide desquels la possibilité de réglage du système de zoom (32) est respectivement limitée à la plage de zoom partielle (96, 98) qui est associée à l'objectif (44, 52) sélectionné, au moins une butée (46, 48, 54, 56) étant prévue comme moyens de limitation sur chaque objectif (44, 52), par laquelle la possibilité de réglage du système de zoom (32) est limitée à la plage de zoom partielle associée à l'objectif (44, 52) respectif, et en ce que l'unité de commande (64) détermine le réglage à effectuer du diaphragme (60) en fonction de l'objectif (44, 52) respectivement sélectionné et/ou de la distance focale réglée du système de zoom (32).
  2. Microscope (10) selon la revendication 1, caractérisé en ce que le microscope (10) comprend en outre un moteur (62) prévu pour régler le diaphragme (60) afin de régler la dimension de l'ouverture du diaphragme (60), et en ce que l'unité de commande (64) actionne automatiquement le moteur (62) de manière à ce que le moteur (62) règle l'ouverture (60) de manière correspondante.
  3. Microscope (10) selon la revendication 1 ou 2, caractérisé en ce que le diaphragme (60) est un diaphragme à iris.
  4. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce que l'unité de commande (64) détermine respectivement le réglage à effectuer du diaphragme (60) en fonction des expressions effectives d'au moins deux paramètres du microscope (10).
  5. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce que, pour toutes les expressions possibles des paramètres pris en compte, les réglages à effectuer du diaphragme (60) sont respectivement stockés dans l'unité de commande (64) en étant associés de manière non ambiguë aux expressions respectives.
  6. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce qu'une instruction de calcul est stockée dans l'unité de commande (64), et en ce que l'unité de commande (64) utilise ladite instruction de calcul pour déterminer le réglage à effectuer du diaphragme (60).
  7. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce que les réglages à effectuer du diaphragme (60) sont prédéterminés de telle manière qu'ils soient respectivement les réglages optimaux du diaphragme (60) pour les expressions respectives des paramètres.
  8. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce que l'unité de commande (64) détermine le réglage à effectuer du diaphragme (60) en fonction du réglage effectif du système de zoom (32).
  9. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce que l'unité de commande (64) détermine le réglage à effectuer du diaphragme (60) en fonction de l'objectif (44, 52) effectivement introduit sur le chemin optique.
  10. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce que l'unité de commande (64) détermine le réglage à effectuer du diaphragme (60) en fonction d'au moins une caractéristique d'au moins un composant matériel (40) du microscope (10).
  11. Microscope (10) selon la revendication 10, caractérisé en ce que l'unité de commande (64) détermine le réglage à effectuer du diaphragme (60) en fonction de la résolution d'une unité d'acquisition d'image (40) du microscope (10), de la sensibilité d'une unité d'acquisition d'image (40) du microscope (10), de la résolution d'une caméra du microscope (10) et/ou de la sensibilité d'une caméra du microscope (10).
  12. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce que l'unité de commande (64) détermine le réglage à effectuer du diaphragme (60) en fonction d'au moins un réglage utilisateur effectué par un utilisateur du microscope (10).
  13. Microscope (10) selon la revendication 12, caractérisé en ce que le réglage utilisateur comprend le temps d'exposition souhaité, un niveau de résolution souhaité, un niveau de profondeur de champ souhaité et/ou un niveau de luminosité souhaité.
  14. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce qu'il est prévu au moins une unité de capteur (66, 68) destinée à déterminer l'expression effective du paramètre ou les expressions effectives des paramètres.
  15. Microscope (10) selon l'une des revendications précédentes, caractérisé en ce que le microscope (10) est un microscope numérique comportant une unité d'acquisition d'image (40) sur laquelle une image de l'objet à examiner au microscope est formée à l'aide du système de zoom (32).
EP15771603.6A 2014-10-06 2015-10-01 Microscope avec diaphragme à iris à adaptation automatique Active EP3204813B2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102014114471.6A DE102014114471C5 (de) 2014-10-06 2014-10-06 Mikroskop mit sich automatisch anpassender Irisblende
PCT/EP2015/072661 WO2016055338A1 (fr) 2014-10-06 2015-10-01 Microscope avec diaphragme à iris à adaptation automatique

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EP3204813A1 EP3204813A1 (fr) 2017-08-16
EP3204813B1 EP3204813B1 (fr) 2019-08-07
EP3204813B2 true EP3204813B2 (fr) 2022-08-24

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EP (1) EP3204813B2 (fr)
JP (1) JP6472514B2 (fr)
CN (1) CN106796341B (fr)
DE (1) DE102014114471C5 (fr)
WO (1) WO2016055338A1 (fr)

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Publication number Publication date
WO2016055338A1 (fr) 2016-04-14
US10234671B2 (en) 2019-03-19
DE102014114471C5 (de) 2021-02-18
EP3204813B1 (fr) 2019-08-07
EP3204813A1 (fr) 2017-08-16
CN106796341B (zh) 2019-08-09
JP2017530416A (ja) 2017-10-12
US20170307868A1 (en) 2017-10-26
JP6472514B2 (ja) 2019-02-20
DE102014114471B4 (de) 2016-06-16
CN106796341A (zh) 2017-05-31
DE102014114471A1 (de) 2016-04-07

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