EP3268496A4 - Dispositifs fet à base de graphène, systèmes, et leurs procédés d'utilisation pour le séquençage d'acides nucléiques - Google Patents

Dispositifs fet à base de graphène, systèmes, et leurs procédés d'utilisation pour le séquençage d'acides nucléiques Download PDF

Info

Publication number
EP3268496A4
EP3268496A4 EP16762454.3A EP16762454A EP3268496A4 EP 3268496 A4 EP3268496 A4 EP 3268496A4 EP 16762454 A EP16762454 A EP 16762454A EP 3268496 A4 EP3268496 A4 EP 3268496A4
Authority
EP
European Patent Office
Prior art keywords
systems
methods
nucleic acids
same
fet devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16762454.3A
Other languages
German (de)
English (en)
Other versions
EP3268496A1 (fr
Inventor
Paul Hoffman
Mitchell LERNER
Pieter ROOYEN van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGILOME, INC.
Original Assignee
Agilome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilome Inc filed Critical Agilome Inc
Publication of EP3268496A1 publication Critical patent/EP3268496A1/fr
Publication of EP3268496A4 publication Critical patent/EP3268496A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP16762454.3A 2015-03-09 2016-03-09 Dispositifs fet à base de graphène, systèmes, et leurs procédés d'utilisation pour le séquençage d'acides nucléiques Withdrawn EP3268496A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562130601P 2015-03-09 2015-03-09
US201562130594P 2015-03-09 2015-03-09
US201562130598P 2015-03-09 2015-03-09
US201562130621P 2015-03-10 2015-03-10
PCT/US2016/021606 WO2016145110A1 (fr) 2015-03-09 2016-03-09 Dispositifs fet à base de graphène, systèmes, et leurs procédés d'utilisation pour le séquençage d'acides nucléiques

Publications (2)

Publication Number Publication Date
EP3268496A1 EP3268496A1 (fr) 2018-01-17
EP3268496A4 true EP3268496A4 (fr) 2018-09-05

Family

ID=56879360

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16762454.3A Withdrawn EP3268496A4 (fr) 2015-03-09 2016-03-09 Dispositifs fet à base de graphène, systèmes, et leurs procédés d'utilisation pour le séquençage d'acides nucléiques

Country Status (2)

Country Link
EP (1) EP3268496A4 (fr)
WO (1) WO2016145110A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160054312A1 (en) 2014-04-28 2016-02-25 Nanomedical Diagnostics, Inc. Chemically differentiated sensor array
US11921112B2 (en) 2014-12-18 2024-03-05 Paragraf Usa Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
US12298301B2 (en) 2014-12-18 2025-05-13 Cardea Bio, Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
US9618474B2 (en) 2014-12-18 2017-04-11 Edico Genome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US11782057B2 (en) 2014-12-18 2023-10-10 Cardea Bio, Inc. Ic with graphene fet sensor array patterned in layers above circuitry formed in a silicon based cmos wafer
US10006910B2 (en) 2014-12-18 2018-06-26 Agilome, Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
WO2017201081A1 (fr) * 2016-05-16 2017-11-23 Agilome, Inc. Dispositifs à fet au graphène, systèmes et leurs méthodes d'utilisation pour le séquençage d'acides nucléiques
US11905552B2 (en) 2017-08-04 2024-02-20 Keck Graduate Institute Of Applied Life Sciences Immobilized RNPs for sequence-specific nucleic acid capture and digital detection
CN114371208B (zh) * 2021-11-30 2024-11-29 山东师范大学 生物传感器制作、检测方法、生物传感器及光电磁系统

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110210314A1 (en) * 2010-02-26 2011-09-01 Samsung Electronics Co., Ltd. Graphene electronic device and method of fabricating the same
US20120214172A1 (en) * 2011-02-18 2012-08-23 Uwm Research Foundation, Inc. Graphene-based field-effect transistor biosensors
US20120220053A1 (en) * 2011-02-17 2012-08-30 Rutgers, The State University Of New Jersey Graphene-encapsulated nanoparticle-based biosensor for the selective detection of biomarkers
US20120286244A1 (en) * 2011-05-10 2012-11-15 International Business Machines Corporation Carbon field effect transistors having charged monolayers to reduce parasitic resistance
WO2014112199A1 (fr) * 2013-01-17 2014-07-24 株式会社日立ハイテクノロジーズ Dispositif de mesure de biomolécules
WO2014176524A2 (fr) * 2013-04-25 2014-10-30 The Trustees Of The University Of Pennsylvania Detection d'opioide basee sur des reseaux de transistors de graphene a qualite elevee et recepteur mu synthétique
EP3235010A1 (fr) * 2014-12-18 2017-10-25 Agilome, Inc. Transistor à effet de champ chimiquement sensible

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8653567B2 (en) * 2010-07-03 2014-02-18 Life Technologies Corporation Chemically sensitive sensor with lightly doped drains
US8962366B2 (en) * 2013-01-28 2015-02-24 Life Technologies Corporation Self-aligned well structures for low-noise chemical sensors

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110210314A1 (en) * 2010-02-26 2011-09-01 Samsung Electronics Co., Ltd. Graphene electronic device and method of fabricating the same
US20120220053A1 (en) * 2011-02-17 2012-08-30 Rutgers, The State University Of New Jersey Graphene-encapsulated nanoparticle-based biosensor for the selective detection of biomarkers
US20120214172A1 (en) * 2011-02-18 2012-08-23 Uwm Research Foundation, Inc. Graphene-based field-effect transistor biosensors
US20120286244A1 (en) * 2011-05-10 2012-11-15 International Business Machines Corporation Carbon field effect transistors having charged monolayers to reduce parasitic resistance
WO2014112199A1 (fr) * 2013-01-17 2014-07-24 株式会社日立ハイテクノロジーズ Dispositif de mesure de biomolécules
EP2947453A1 (fr) * 2013-01-17 2015-11-25 Hitachi High-Technologies Corporation Dispositif de mesure de biomolécules
WO2014176524A2 (fr) * 2013-04-25 2014-10-30 The Trustees Of The University Of Pennsylvania Detection d'opioide basee sur des reseaux de transistors de graphene a qualite elevee et recepteur mu synthétique
EP3235010A1 (fr) * 2014-12-18 2017-10-25 Agilome, Inc. Transistor à effet de champ chimiquement sensible

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2016145110A1 *

Also Published As

Publication number Publication date
WO2016145110A1 (fr) 2016-09-15
EP3268496A1 (fr) 2018-01-17

Similar Documents

Publication Publication Date Title
EP3161700A4 (fr) Procédés et systèmes pour l'assemblage de séquences d'acide nucléique
EP3157573A4 (fr) Molécules d'acide nucléique alternatives et leurs utilisations
EP3157572A4 (fr) Molécules d'acide nucléique alternatives et leurs utilisations
EP3175023A4 (fr) Systèmes et méthodes permettant de déterminer des acides nucléiques
EP3271848A4 (fr) Systèmes et procédés pour analyser l'acide nucléique
EP3684951A4 (fr) Systèmes et procédés de séquençage d'acides nucléiques
EP3332034A4 (fr) Systèmes et procédés d'analyse génomique
EP3268496A4 (fr) Dispositifs fet à base de graphène, systèmes, et leurs procédés d'utilisation pour le séquençage d'acides nucléiques
EP3349678A4 (fr) Systèmes robotiques chirurgicaux et procédés associés
EP3294122A4 (fr) Système et procédé de séquençage d'ultrasons
EP3191009A4 (fr) Effecteurs d'extrémité à libération rapide et systèmes et procédés associés
EP3095054A4 (fr) Procédés et systèmes d'analyse génomique
EP3164510A4 (fr) Procédé, substrat et dispositif permettant de séparer des acides nucléiques
EP3232941A4 (fr) Procédé chirurgical et système pour conduire celui-ci
EP3134536A4 (fr) Systèmes et procédés permettant de marquer des acides nucléiques avec un code à barres
EP3218098A4 (fr) Systèmes et procédés de microréacteur
EP3132060A4 (fr) Procédés et systèmes pour l'amplification d'acide nucléique
EP3405573A4 (fr) Procédés et systèmes de séquençage haute fidélité
EP3114315A4 (fr) Systèmes de géoguidage et procédés associés
EP3205370A4 (fr) Dispositif d'ablation chimique et système d'ablation chimique
EP3284320A4 (fr) Système de gradation vers le chaud et procédé pour l'utiliser
EP3169941A4 (fr) Système de ventilation et de séchage et procédé d'utilisation de celui-ci
EP3247716A4 (fr) Inhibiteurs de mir-92 et utilisations associées
EP3105579A4 (fr) Système de chromatographie à multiples colonnes et procédés d'utilisation
EP3326704A4 (fr) Système de distillation et procédé de distillation associé

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20171006

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: AGILOME, INC.

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20180808

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 27/414 20060101ALI20180802BHEP

Ipc: H01L 21/335 20060101ALI20180802BHEP

Ipc: C12Q 1/68 20180101AFI20180802BHEP

RIN1 Information on inventor provided before grant (corrected)

Inventor name: HOFFMAN, PAUL

Inventor name: LERNER, MITCHELL

Inventor name: ROOYEN VAN, PIETER

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20191001