EP3283087A4 - Verfahren und system für mikrobiomderivierte diagnostika und therapeutika für erkrankungen des endokrinen systems - Google Patents

Verfahren und system für mikrobiomderivierte diagnostika und therapeutika für erkrankungen des endokrinen systems Download PDF

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Publication number
EP3283087A4
EP3283087A4 EP16780681.9A EP16780681A EP3283087A4 EP 3283087 A4 EP3283087 A4 EP 3283087A4 EP 16780681 A EP16780681 A EP 16780681A EP 3283087 A4 EP3283087 A4 EP 3283087A4
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EP
European Patent Office
Prior art keywords
microbioma
diagnoses
dysfunctions
endocrine
treatments derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16780681.9A
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English (en)
French (fr)
Other versions
EP3283087A1 (de
Inventor
Zachary APTE
Daniel Almonacid
Jessica RICHMAN
Siavosh Rezvan BEHBAHANI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Macrogen Inc
Original Assignee
uBiome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by uBiome Inc filed Critical uBiome Inc
Publication of EP3283087A1 publication Critical patent/EP3283087A1/de
Publication of EP3283087A4 publication Critical patent/EP3283087A4/de
Pending legal-status Critical Current

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Data Mining & Analysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Databases & Information Systems (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Primary Health Care (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Software Systems (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
EP16780681.9A 2015-04-14 2016-04-13 Verfahren und system für mikrobiomderivierte diagnostika und therapeutika für erkrankungen des endokrinen systems Pending EP3283087A4 (de)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201562147058P 2015-04-14 2015-04-14
US201562147202P 2015-04-14 2015-04-14
US201562147107P 2015-04-14 2015-04-14
US201562147348P 2015-04-14 2015-04-14
US201562147355P 2015-04-14 2015-04-14
US201562147226P 2015-04-14 2015-04-14
US201562147304P 2015-04-14 2015-04-14
PCT/US2016/027378 WO2016168370A1 (en) 2015-04-14 2016-04-13 Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions

Publications (2)

Publication Number Publication Date
EP3283087A1 EP3283087A1 (de) 2018-02-21
EP3283087A4 true EP3283087A4 (de) 2019-03-13

Family

ID=57126198

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16780681.9A Pending EP3283087A4 (de) 2015-04-14 2016-04-13 Verfahren und system für mikrobiomderivierte diagnostika und therapeutika für erkrankungen des endokrinen systems

Country Status (4)

Country Link
EP (1) EP3283087A4 (de)
CN (1) CN107708714B (de)
AU (2) AU2016250159A1 (de)
WO (1) WO2016168370A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016321348A1 (en) * 2015-09-09 2018-04-26 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with thyroid health issues
WO2019178610A1 (en) * 2018-03-16 2019-09-19 uBiome, Inc. Method and system for characterization of metabolism-associated conditions, including diagnostics and therapies, based on bioinformatics approach
CN114381507B (zh) * 2021-11-25 2024-02-13 杭州拓宏生物科技有限公司 格雷夫斯病标志微生物及其应用
WO2025131250A1 (en) * 2023-12-19 2025-06-26 N.V. Nutricia A system and method for analysing excreta
CN119296652B (zh) * 2024-09-24 2025-10-21 河北大学 美国白蛾幼虫唾液及雌虫产卵分泌物效应因子筛选方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130121968A1 (en) * 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
WO2015013214A2 (en) * 2013-07-21 2015-01-29 Whole Biome, Inc. Methods and systems for microbiome characterization, monitoring and treatment

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011022660A1 (en) * 2009-08-21 2011-02-24 Puretech Ventures, Llc Methods of diagnosing and treating microbiome-associated disease using interaction network parameters
NZ602704A (en) * 2010-03-01 2015-01-30 Agronomique Inst Nat Rech Method of diagnostic of inflammatory bowel diseases
JP2013520973A (ja) * 2010-03-01 2013-06-10 アンスティテュ ナシオナル ドゥ ラ ルシェルシュ アグロノミック 肥満診断方法
US20150209383A1 (en) * 2011-11-04 2015-07-30 General Mills, Inc. Methods and compositions for modulating gastrointestinal bacteria to promote health
US11185562B2 (en) * 2013-02-04 2021-11-30 Seres Therapeutics, Inc. Compositions and methods for inhibition of pathogenic bacterial growth
WO2014190229A1 (en) * 2013-05-24 2014-11-27 President And Fellows Of Harvard College Methods of isolating microorganisms and uses thereof
US20150050245A1 (en) * 2013-08-14 2015-02-19 Tntgamble, Inc. Methods and delivery system for beneficial additive and subtractive biological agents to promote balanced mammalian gastrointestinal flora
EP3209803A4 (de) * 2014-10-21 2018-06-13 Ubiome, Inc. Verfahren und zusammensetzungen für mikrobiom-diagnostika und -therapeutika
CA2964480A1 (en) * 2014-10-31 2016-05-06 Whole Biome Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
WO2016168354A1 (en) * 2015-04-13 2016-10-20 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features
CN108283012B (zh) * 2015-04-13 2021-11-23 普梭梅根公司 用于自身免疫系统状况的微生物组来源的诊断和治疗的方法及系统
EP3283085A4 (de) * 2015-04-13 2019-04-10 Ubiome, Inc. Verfahren und system für mikrobiomabgeleitete diagnosemittel und therapeutika für erkrankungen im zusammenhang mit taxonomen mikrobiommerkmalen
AU2016248115A1 (en) * 2015-04-14 2017-11-09 Psomagen, Inc. Method and system for microbiome-derived characterization, diagnostics, and therapeutics for cardiovascular disease conditions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130121968A1 (en) * 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
WO2015013214A2 (en) * 2013-07-21 2015-01-29 Whole Biome, Inc. Methods and systems for microbiome characterization, monitoring and treatment

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO2016168370A1 *
VIRILI CAMILLA ET AL: "Does microbiota composition affect thyroid homeostasis?", ENDOCRINE, HUMANA PRESS, INC, US, vol. 49, no. 3, 17 December 2014 (2014-12-17), pages 583 - 587, XP035520794, ISSN: 1355-008X, [retrieved on 20141217], DOI: 10.1007/S12020-014-0509-2 *

Also Published As

Publication number Publication date
AU2016250159A1 (en) 2017-11-09
EP3283087A1 (de) 2018-02-21
WO2016168370A1 (en) 2016-10-20
CN107708714B (zh) 2022-07-22
CN107708714A (zh) 2018-02-16
AU2022200575A1 (en) 2022-02-17

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