EP3307913A4 - Procédés de diagnostic et de traitement de l'autisme - Google Patents
Procédés de diagnostic et de traitement de l'autisme Download PDFInfo
- Publication number
- EP3307913A4 EP3307913A4 EP16812321.4A EP16812321A EP3307913A4 EP 3307913 A4 EP3307913 A4 EP 3307913A4 EP 16812321 A EP16812321 A EP 16812321A EP 3307913 A4 EP3307913 A4 EP 3307913A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- diagnosing
- methods
- treating autism
- autism
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/740,230 US11219617B2 (en) | 2014-05-30 | 2015-06-15 | Methods of diagnosing and treating autism |
| US201562215636P | 2015-09-08 | 2015-09-08 | |
| US201562215673P | 2015-09-08 | 2015-09-08 | |
| US201562215633P | 2015-09-08 | 2015-09-08 | |
| US201562215628P | 2015-09-08 | 2015-09-08 | |
| PCT/US2016/037596 WO2016205348A1 (fr) | 2015-06-15 | 2016-06-15 | Procédés de diagnostic et de traitement de l'autisme |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3307913A1 EP3307913A1 (fr) | 2018-04-18 |
| EP3307913A4 true EP3307913A4 (fr) | 2019-03-27 |
Family
ID=57546224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP16812321.4A Withdrawn EP3307913A4 (fr) | 2015-06-15 | 2016-06-15 | Procédés de diagnostic et de traitement de l'autisme |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP3307913A4 (fr) |
| CN (1) | CN108474036A (fr) |
| AU (1) | AU2016278053A1 (fr) |
| CA (1) | CA2989326A1 (fr) |
| WO (1) | WO2016205348A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2807505A1 (fr) | 2010-08-24 | 2012-03-01 | The Children's Hospital Of Philadelphia | Association de variations genetiques recurrentes rares du trouble du deficit de l'attention avec hyperactivite (tdah) et procedes d'utilisation associes pour le diagnostic et le traitement du tdah |
| WO2017044491A1 (fr) | 2015-09-08 | 2017-03-16 | The Children's Hospital Of Philadelphia | Activateurs du récepteur métabotropique du glutamate non sélectifs pour le traitement du trouble déficitaire de l'attention et du syndrome 22q |
| US11684617B2 (en) | 2017-04-19 | 2023-06-27 | The Children's Hospital Of Philadelphia | Methods of diagnosing and treating ADHD in biomarker positive subjects |
| CN109813912B (zh) * | 2019-01-04 | 2021-12-28 | 深圳大学 | 一组血清差异蛋白组合在制备用于检测孤独症的试剂中的应用 |
| KR102639856B1 (ko) * | 2020-10-14 | 2024-02-23 | 한국원자력의학원 | 미세플라스틱 노출에 의해 유도되는 뇌질환 예후 예측용 바이오마커 조성물 및 이를 이용한 예후 예측방법 |
| CN113706458B (zh) * | 2021-07-15 | 2023-03-28 | 电子科技大学 | 基于Gossip模型的自闭症检测装置 |
| CN114446476B (zh) * | 2022-01-28 | 2023-02-17 | 中南大学湘雅二医院 | 孤独症治疗效果预测模型构建方法、预测方法及装置 |
| CN119044511B (zh) * | 2024-11-01 | 2025-01-28 | 中日友好医院(中日友好临床医学研究所) | Dkd早期诊断的生物标志物、分析方法、试剂盒及应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US20140315992A1 (en) * | 2011-07-07 | 2014-10-23 | The Children's Hospital Of Philadelphia | Genetic Alterations Associated with Autism and the Autistic Phenotype and Methods of Use Thereof for the Diagnosis and Treatment of Autism |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1202962A (fr) | 1982-10-19 | 1986-04-08 | David P. Clifford | Derives de substitution de n-phenyl-n'-benzoyl-uree; leur utilisation comme insecticides et comme acaricides |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| FR2597100A1 (fr) | 1986-01-21 | 1987-10-16 | Nippon Shinyaku Co Ltd | Derives du pyroglutamide |
| US20140216734A1 (en) * | 2013-02-05 | 2014-08-07 | Schlumberger Technology Corporation | Casing collar location using elecromagnetic wave phase shift measurement |
| WO2014152965A2 (fr) * | 2013-03-14 | 2014-09-25 | The Children's Hospital Of Philadelphia | Loci génétiques associés à la schizophrénie identifiés dans des études d'association sur génome total et leur utilisation en tant que nouvelles cibles thérapeutiques |
-
2016
- 2016-06-15 EP EP16812321.4A patent/EP3307913A4/fr not_active Withdrawn
- 2016-06-15 CN CN201680048195.4A patent/CN108474036A/zh active Pending
- 2016-06-15 AU AU2016278053A patent/AU2016278053A1/en not_active Abandoned
- 2016-06-15 WO PCT/US2016/037596 patent/WO2016205348A1/fr not_active Ceased
- 2016-06-15 CA CA2989326A patent/CA2989326A1/fr not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US20140315992A1 (en) * | 2011-07-07 | 2014-10-23 | The Children's Hospital Of Philadelphia | Genetic Alterations Associated with Autism and the Autistic Phenotype and Methods of Use Thereof for the Diagnosis and Treatment of Autism |
Non-Patent Citations (3)
| Title |
|---|
| GREGORY KAREN J ET AL: "Pharmacology of metabotropic glutamate receptor allosteric modulators: structural basis and therapeutic potential for CNS disorders", PROGRESS IN MOLECULAR BIOLOGY AND TRANSLATIONAL SCI, ELSEVIER, NL, vol. 115, 1 January 2013 (2013-01-01), pages 61 - 121, XP009192627, ISSN: 1878-0814, DOI: 10.1016/B978-0-12-394587-7.00002-6 * |
| MALYKH ANDREI G ET AL: "Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders", DRUGS, SPRINGER INTERNATIONAL PUBLISHING, vol. 70, no. 3, 1 January 2010 (2010-01-01), pages 287 - 312, XP009162620, ISSN: 0012-6667, DOI: 10.2165/11319230-000000000-00000 * |
| See also references of WO2016205348A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3307913A1 (fr) | 2018-04-18 |
| CN108474036A (zh) | 2018-08-31 |
| WO2016205348A1 (fr) | 2016-12-22 |
| AU2016278053A1 (en) | 2018-01-04 |
| CA2989326A1 (fr) | 2016-12-22 |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| DAV | Request for validation of the european patent (deleted) | ||
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| RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: GLESSNER, JOSEPH Inventor name: WENGER, TARA Inventor name: HAKONARSON, HAKON Inventor name: HADLEY, DEXTER Inventor name: WU, ZHI-LIANG Inventor name: KAO, CHARLLY |
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| A4 | Supplementary search report drawn up and despatched |
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| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 25/00 20060101ALI20190219BHEP Ipc: C12Q 1/68 20180101ALI20190219BHEP Ipc: A61K 31/454 20060101AFI20190219BHEP Ipc: G01N 33/68 20060101ALI20190219BHEP |
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