EP3347497A4 - Nukleinsäureanalyse durch verbinden von barcodierten polynukleotidsonden - Google Patents

Nukleinsäureanalyse durch verbinden von barcodierten polynukleotidsonden Download PDF

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Publication number
EP3347497A4
EP3347497A4 EP16845310.8A EP16845310A EP3347497A4 EP 3347497 A4 EP3347497 A4 EP 3347497A4 EP 16845310 A EP16845310 A EP 16845310A EP 3347497 A4 EP3347497 A4 EP 3347497A4
Authority
EP
European Patent Office
Prior art keywords
nucleic acid
acid analysis
polynucleotide barcode
barcode probes
assembling polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16845310.8A
Other languages
English (en)
French (fr)
Other versions
EP3347497A2 (de
Inventor
Heather Koshinsky
John D. Curry
Robert O'CALLAHAN
Adam MCCOY
Daniel Fitzpatrick
Philip H. Dickinson
Anthony C. Schweitzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymetrix Inc
Original Assignee
Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Publication of EP3347497A2 publication Critical patent/EP3347497A2/de
Publication of EP3347497A4 publication Critical patent/EP3347497A4/de
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP16845310.8A 2016-01-31 2016-11-08 Nukleinsäureanalyse durch verbinden von barcodierten polynukleotidsonden Pending EP3347497A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662289303P 2016-01-31 2016-01-31
US201662317879P 2016-04-04 2016-04-04
US201662353088P 2016-06-22 2016-06-22
PCT/US2016/060991 WO2017044993A2 (en) 2015-09-08 2016-11-08 Nucleic acid analysis by joining barcoded polynucleotide probes

Publications (2)

Publication Number Publication Date
EP3347497A2 EP3347497A2 (de) 2018-07-18
EP3347497A4 true EP3347497A4 (de) 2019-01-23

Family

ID=62083370

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16845310.8A Pending EP3347497A4 (de) 2016-01-31 2016-11-08 Nukleinsäureanalyse durch verbinden von barcodierten polynukleotidsonden

Country Status (3)

Country Link
EP (1) EP3347497A4 (de)
CN (1) CN108026568A (de)
WO (1) WO2017044993A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2019004080A1 (ja) * 2017-06-27 2020-04-23 国立大学法人 東京大学 融合遺伝子及び／又はエクソンスキッピングにより生ずる転写産物を検出するためのプローブ及び方法
US11639928B2 (en) * 2018-02-22 2023-05-02 10X Genomics, Inc. Methods and systems for characterizing analytes from individual cells or cell populations
SG11202008080RA (en) * 2018-02-22 2020-09-29 10X Genomics Inc Ligation mediated analysis of nucleic acids
US11519033B2 (en) 2018-08-28 2022-12-06 10X Genomics, Inc. Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
CN111100935B (zh) * 2018-10-26 2023-03-31 厦门大学 一种细菌耐药基因检测的方法
WO2020123316A2 (en) 2018-12-10 2020-06-18 10X Genomics, Inc. Methods for determining a location of a biological analyte in a biological sample
EP3906321A1 (de) * 2018-12-31 2021-11-10 HTG Molecular Diagnostics, Inc. Verfahren zum nachweis von dna und rna in derselben probe
WO2020243579A1 (en) 2019-05-30 2020-12-03 10X Genomics, Inc. Methods of detecting spatial heterogeneity of a biological sample
CN110408717A (zh) * 2019-07-23 2019-11-05 四川省农业科学院生物技术核技术研究所 灵芝属线粒体rns基因的特异扩增引物及其应用
EP4081656A1 (de) 2019-12-23 2022-11-02 10X Genomics, Inc. Zusammensetzungen und verfahren zur verwendung von fixierten biologischen proben bei partitionsbasierten tests
CN115135984B (zh) 2019-12-23 2025-12-23 10X基因组学有限公司 可逆固定试剂及其使用方法
ES2982420T3 (es) * 2019-12-23 2024-10-16 10X Genomics Inc Métodos para el análisis espacial mediante el uso de la ligazón con plantilla de ARN
US12365942B2 (en) 2020-01-13 2025-07-22 10X Genomics, Inc. Methods of decreasing background on a spatial array
US12405264B2 (en) 2020-01-17 2025-09-02 10X Genomics, Inc. Electrophoretic system and method for analyte capture
US20210230681A1 (en) 2020-01-24 2021-07-29 10X Genomics, Inc. Methods for spatial analysis using proximity ligation
US11732300B2 (en) 2020-02-05 2023-08-22 10X Genomics, Inc. Increasing efficiency of spatial analysis in a biological sample
US12281357B1 (en) 2020-02-14 2025-04-22 10X Genomics, Inc. In situ spatial barcoding
US12553077B2 (en) * 2020-10-01 2026-02-17 Google Llc Linked dual barcode insertion constructs
EP4729631A2 (de) 2020-12-21 2026-04-22 10X Genomics, Inc. Verfahren, zusammensetzungen und systeme zur erfassung von sonden und/oder barcodes
US20240182955A1 (en) * 2021-02-17 2024-06-06 Act Genomics (ip) Limited Dna fragment joining detecting method and kit thereof
CN117015617B (zh) 2021-02-23 2025-04-04 10X基因组学有限公司 基于探针的核酸和蛋白质分析
EP4320271B1 (de) 2021-05-06 2025-03-19 10X Genomics, Inc. Verfahren zur erhöhung der auflösung von räumlicher analyse
WO2023086880A1 (en) 2021-11-10 2023-05-19 10X Genomics, Inc. Methods, compositions, and kits for determining the location of an analyte in a biological sample
EP4482979B1 (de) 2022-11-09 2025-10-01 10X Genomics, Inc. Verfahren, zusammensetzungen und kits zur bestimmung der position mehrerer analyten in einer biologischen probe

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005001113A2 (en) * 2003-06-27 2005-01-06 Thomas Jefferson University Methods for detecting nucleic acid variations
WO2005021794A2 (en) * 2003-09-02 2005-03-10 Keygene N.V. Ola-based methods for the detection of target nucleic acid sequences

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
US5912124A (en) * 1996-06-14 1999-06-15 Sarnoff Corporation Padlock probe detection
JP2007530051A (ja) * 2004-03-24 2007-11-01 アプレラ コーポレイション 標的分子を決定するためのライゲーション反応および増幅反応
CA2597330A1 (en) * 2005-02-09 2006-08-17 Stratagene California Key probe compositions and methods for polynucleotide detection
EP1991698B1 (de) * 2006-03-01 2013-12-18 Keygene N.V. Snp-nachweis auf sequenzbasis mit hohem durchsatz unter verwendung von ligationsassays
WO2013106807A1 (en) * 2012-01-13 2013-07-18 Curry John D Scalable characterization of nucleic acids by parallel sequencing
CN104830993B (zh) * 2015-06-08 2017-08-18 中国海洋大学 一种高通量、多种类型分子标记通用的分型技术

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005001113A2 (en) * 2003-06-27 2005-01-06 Thomas Jefferson University Methods for detecting nucleic acid variations
WO2005021794A2 (en) * 2003-09-02 2005-03-10 Keygene N.V. Ola-based methods for the detection of target nucleic acid sequences

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
L. KVASTAD ET AL: "Single cell analysis of cancer cells using an improved RT-MLPA method has potential for cancer diagnosis and monitoring", SCIENTIFIC REPORTS, vol. 5, no. 1, 12 November 2015 (2015-11-12), XP055535938, DOI: 10.1038/srep16519 *

Also Published As

Publication number Publication date
EP3347497A2 (de) 2018-07-18
WO2017044993A3 (en) 2017-04-27
WO2017044993A2 (en) 2017-03-16
CN108026568A (zh) 2018-05-11

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