EP3498373A4 - Mikrofluidische vorrichtung und herstellungsverfahren dafür - Google Patents

Mikrofluidische vorrichtung und herstellungsverfahren dafür Download PDF

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Publication number
EP3498373A4
EP3498373A4 EP17839627.1A EP17839627A EP3498373A4 EP 3498373 A4 EP3498373 A4 EP 3498373A4 EP 17839627 A EP17839627 A EP 17839627A EP 3498373 A4 EP3498373 A4 EP 3498373A4
Authority
EP
European Patent Office
Prior art keywords
manufacturing
microfluidic device
microfluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP17839627.1A
Other languages
English (en)
French (fr)
Other versions
EP3498373A1 (de
EP3498373B1 (de
Inventor
Chae Seung Lim
Jeong Hun Nam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea University Research and Business Foundation
Original Assignee
Korea University Research and Business Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea University Research and Business Foundation filed Critical Korea University Research and Business Foundation
Priority claimed from PCT/KR2017/003865 external-priority patent/WO2018030609A1/ko
Publication of EP3498373A1 publication Critical patent/EP3498373A1/de
Publication of EP3498373A4 publication Critical patent/EP3498373A4/de
Application granted granted Critical
Publication of EP3498373B1 publication Critical patent/EP3498373B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0436—Moving fluids with specific forces or mechanical means specific forces vibrational forces acoustic forces, e.g. surface acoustic waves [SAW]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0493—Specific techniques used

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
EP17839627.1A 2016-08-12 2017-04-10 Mikrofluidische vorrichtung und herstellungsverfahren dafür Active EP3498373B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20160102883 2016-08-12
KR1020160116705A KR101891401B1 (ko) 2016-08-12 2016-09-09 미세유체 소자 및 이의 제조방법
PCT/KR2017/003865 WO2018030609A1 (ko) 2016-08-12 2017-04-10 미세유체 소자 및 이의 제조방법

Publications (3)

Publication Number Publication Date
EP3498373A1 EP3498373A1 (de) 2019-06-19
EP3498373A4 true EP3498373A4 (de) 2020-02-26
EP3498373B1 EP3498373B1 (de) 2024-08-21

Family

ID=61524990

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17839627.1A Active EP3498373B1 (de) 2016-08-12 2017-04-10 Mikrofluidische vorrichtung und herstellungsverfahren dafür

Country Status (3)

Country Link
EP (1) EP3498373B1 (de)
KR (1) KR101891401B1 (de)
CN (1) CN109641210B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220004107A (ko) * 2019-04-24 2022-01-11 더 리전츠 오브 더 유니버시티 오브 캘리포니아 마이크로입자 및 세포 패턴화를 위한 임의 형상화, 깊은 하위파장 음향 조작
EP3795252B1 (de) * 2019-09-19 2025-12-24 Sharp Life Science (EU) Limited Leitfähiger abstandshalter für eine mikrofluidische vorrichtung
KR102218278B1 (ko) 2019-11-08 2021-02-19 울산과학기술원 습도 제어를 통한 나노채널의 물질전달 제어장치
CN111046607B (zh) * 2019-12-12 2025-05-13 浙江清华柔性电子技术研究院 柔性微流体器件设计方法及柔性微流体器件
CN112019185A (zh) * 2020-09-03 2020-12-01 杨欣 全覆盖式声表面波叉指换能器
CN116060146A (zh) * 2023-01-30 2023-05-05 上海纬冉科技有限公司 一种微流控芯片及其制备方法、分离方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008069551A1 (en) * 2006-12-05 2008-06-12 Electronics And Telecommunications Research Institute Micro fluidic transportation device and method for manufacturing the same
US20100139377A1 (en) * 2008-12-05 2010-06-10 The Penn State Reserch Foundation Particle focusing within a microfluidic device using surface acoustic waves
US20100200092A1 (en) * 2007-07-26 2010-08-12 Fabio Beltram Device for controlling fluid motion into micro/nanochannels by means of surface acoustic waves
US20130192958A1 (en) * 2012-01-31 2013-08-01 The Penn State Research Foundation Microfluidic manipulation and sorting of particles using tunable standing surface acoustic wave
US20150330887A1 (en) * 2012-12-28 2015-11-19 Korea University Research And Business Foundation Apparatus and method for microparticle separation based on microfluidic chromatography using surface acoustic wave

Family Cites Families (10)

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KR100862379B1 (ko) * 2007-04-25 2008-10-13 삼성전기주식회사 표면탄성파 디바이스 패키지 및 그 제조방법
CA2716411C (en) * 2008-02-27 2015-11-24 Boehringer Ingelheim Microparts Gmbh Apparatus for the separation of plasma
CN101497006B (zh) * 2009-01-15 2011-04-20 宁波大学 一种数字微流体微混合器及混合方法
KR101183436B1 (ko) * 2010-03-15 2012-09-14 연세대학교 산학협력단 미세유체 칩 및 그 제조방법, 상기 미세유체칩의 미세채널 구조 및 그 제조방법
GB201103211D0 (en) * 2011-02-24 2011-04-13 Univ Glasgow Fluidics apparatus, use of fluidics apparatus and process for the manufacture of fluidics apparatus
CN102284265B (zh) * 2011-06-10 2014-03-12 宁波大学 一种以声表面波为能量源的微反应器及其反应方法
ITTO20110900A1 (it) * 2011-10-10 2013-04-11 Consiglio Nazionale Ricerche Controllo automatico passivo del posizionamento di liquidi in chip microfluidici
WO2014004908A1 (en) * 2012-06-27 2014-01-03 Advanced Liquid Logic Inc. Techniques and droplet actuator designs for reducing bubble formation
US10266397B2 (en) * 2014-08-13 2019-04-23 University Of South Carolina III-V nitride resonate structure based photoacoustic sensor
FR3027672B1 (fr) * 2014-10-24 2018-11-23 Biomerieux Methode et dispositifs de traitement d'echantillons biologiques

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008069551A1 (en) * 2006-12-05 2008-06-12 Electronics And Telecommunications Research Institute Micro fluidic transportation device and method for manufacturing the same
US20100200092A1 (en) * 2007-07-26 2010-08-12 Fabio Beltram Device for controlling fluid motion into micro/nanochannels by means of surface acoustic waves
US20100139377A1 (en) * 2008-12-05 2010-06-10 The Penn State Reserch Foundation Particle focusing within a microfluidic device using surface acoustic waves
US20130192958A1 (en) * 2012-01-31 2013-08-01 The Penn State Research Foundation Microfluidic manipulation and sorting of particles using tunable standing surface acoustic wave
US20150330887A1 (en) * 2012-12-28 2015-11-19 Korea University Research And Business Foundation Apparatus and method for microparticle separation based on microfluidic chromatography using surface acoustic wave

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2018030609A1 *

Also Published As

Publication number Publication date
KR20180018233A (ko) 2018-02-21
KR101891401B1 (ko) 2018-08-23
CN109641210A (zh) 2019-04-16
EP3498373A1 (de) 2019-06-19
EP3498373B1 (de) 2024-08-21
CN109641210B (zh) 2021-03-30

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