EP3523312A4 - Multimodale biosonde für blasenkrebsbildgebung und fotodynamische therapie - Google Patents
Multimodale biosonde für blasenkrebsbildgebung und fotodynamische therapie Download PDFInfo
- Publication number
- EP3523312A4 EP3523312A4 EP17857842.3A EP17857842A EP3523312A4 EP 3523312 A4 EP3523312 A4 EP 3523312A4 EP 17857842 A EP17857842 A EP 17857842A EP 3523312 A4 EP3523312 A4 EP 3523312A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- probe
- bladder cancer
- photodynamic therapy
- cancer imaging
- multimodal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010005003 Bladder cancer Diseases 0.000 title 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 title 1
- 238000003384 imaging method Methods 0.000 title 1
- 238000002428 photodynamic therapy Methods 0.000 title 1
- 239000000523 sample Substances 0.000 title 1
- 201000005112 urinary bladder cancer Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662404222P | 2016-10-05 | 2016-10-05 | |
| US15/352,561 US9840522B2 (en) | 2014-11-09 | 2016-11-15 | Multi-modal bioprobe for bladder cancer imaging and photodynamic therapy |
| PCT/CN2017/104492 WO2018064961A1 (en) | 2016-10-05 | 2017-09-29 | Multi-modal bioprobe for bladder cancer imaging and photodynamic therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3523312A1 EP3523312A1 (de) | 2019-08-14 |
| EP3523312A4 true EP3523312A4 (de) | 2020-09-16 |
Family
ID=61830766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP17857842.3A Pending EP3523312A4 (de) | 2016-10-05 | 2017-09-29 | Multimodale biosonde für blasenkrebsbildgebung und fotodynamische therapie |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3523312A4 (de) |
| CN (1) | CN109863154B (de) |
| TW (1) | TWI687231B (de) |
| WO (1) | WO2018064961A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2766513C1 (ru) * | 2021-03-16 | 2022-03-15 | Федеральное государственное бюджетное учреждение науки Институт радиотехники и электроники им. В.А. Котельникова Российской академии наук | Нанокомпозиты для магнитолюминесцентной тераностики новообразований |
| CN116333037A (zh) * | 2021-12-17 | 2023-06-27 | 化学与精细化工广东省实验室 | 含巯基肽与氟代卟啉类偶联用作生物探针 |
| CN118542940B (zh) * | 2024-07-25 | 2024-11-19 | 深圳大学 | 一种靶向溶酶体的aie光动力纳米颗粒及其制备方法和应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016070851A1 (en) * | 2014-11-09 | 2016-05-12 | Hong Kong Baptist University | Selective cancer tracking eradicator and the uses thereof |
-
2017
- 2017-09-29 CN CN201780062324.XA patent/CN109863154B/zh active Active
- 2017-09-29 WO PCT/CN2017/104492 patent/WO2018064961A1/en not_active Ceased
- 2017-09-29 TW TW106133968A patent/TWI687231B/zh active
- 2017-09-29 EP EP17857842.3A patent/EP3523312A4/de active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016070851A1 (en) * | 2014-11-09 | 2016-05-12 | Hong Kong Baptist University | Selective cancer tracking eradicator and the uses thereof |
Non-Patent Citations (3)
| Title |
|---|
| LIN TZU-YIN ET AL: "Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 104, 22 July 2016 (2016-07-22), pages 339 - 351, XP029681225, ISSN: 0142-9612, DOI: 10.1016/J.BIOMATERIALS.2016.07.026 * |
| See also references of WO2018064961A1 * |
| XUN-JIN ZHU ET AL: "Synthesis, Characterization, and DNA-Binding and -Photocleavage Properties of Water-Soluble Lanthanide Porphyrinate Complexes", CHEMISTRY - A EUROPEAN JOURNAL, vol. 17, no. 25, 14 June 2011 (2011-06-14), DE, pages 7041 - 7052, XP055596926, ISSN: 0947-6539, DOI: 10.1002/chem.201003342 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018064961A1 (en) | 2018-04-12 |
| TW201818975A (zh) | 2018-06-01 |
| EP3523312A1 (de) | 2019-08-14 |
| CN109863154B (zh) | 2021-09-17 |
| TWI687231B (zh) | 2020-03-11 |
| CN109863154A (zh) | 2019-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20190417 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| AX | Request for extension of the european patent |
Extension state: BA ME |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 35/00 20060101ALI20200507BHEP Ipc: A61K 47/64 20170101ALI20200507BHEP Ipc: A61K 41/00 20200101AFI20200507BHEP |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Free format text: PREVIOUS MAIN CLASS: C07F0005000000 Ipc: A61K0041000000 |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20200818 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 35/00 20060101ALI20200812BHEP Ipc: A61K 47/64 20170101ALI20200812BHEP Ipc: A61K 41/00 20200101AFI20200812BHEP |