EP3554496A4 - Verfahren und zusammensetzungen zur behandlung von morbus parkinson - Google Patents

Verfahren und zusammensetzungen zur behandlung von morbus parkinson Download PDF

Info

Publication number: EP3554496A4
Authority: EP; European Patent Office
Prior art keywords: disease; compositions; methods; treating parkinson; parkinson
Prior art date: 2016-12-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP17880499.3A

Other languages

English (en)

French (fr)

Other versions

EP3554496A1 (de

Inventor

Matthew Carl LAWYER

Carl Henry LAWYER

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cove Bio LLC

Original Assignee

Cove Bio LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-12-13

Filing date

2017-12-13

Publication date

2020-05-13

2017-12-13 Application filed by Cove Bio LLC filed Critical Cove Bio LLC

2019-10-23 Publication of EP3554496A1 publication Critical patent/EP3554496A1/de

2020-05-13 Publication of EP3554496A4 publication Critical patent/EP3554496A4/de

Status Withdrawn legal-status Critical Current

Links

208000018737 Parkinson disease Diseases 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Psychology (AREA)
Molecular Biology (AREA)
Inorganic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP17880499.3A 2016-12-13 2017-12-13 Verfahren und zusammensetzungen zur behandlung von morbus parkinson Withdrawn EP3554496A4 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201662433324P	2016-12-13	2016-12-13
US201762504898P	2017-05-11	2017-05-11
PCT/US2017/066218 WO2018112106A1 (en)	2016-12-13	2017-12-13	Methods and compositions for treating parkinson's disease

Publications (2)

Publication Number	Publication Date
EP3554496A1 EP3554496A1 (de)	2019-10-23
EP3554496A4 true EP3554496A4 (de)	2020-05-13

Family

ID=62559231

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP17880499.3A Withdrawn EP3554496A4 (de)	2016-12-13	2017-12-13	Verfahren und zusammensetzungen zur behandlung von morbus parkinson

Country Status (7)

Country	Link
EP (1)	EP3554496A4 (de)
JP (1)	JP2020502269A (de)
CN (1)	CN110753543A (de)
AU (1)	AU2017376458A1 (de)
CA (1)	CA3046501A1 (de)
MX (1)	MX2019007041A (de)
WO (1)	WO2018112106A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN113905715B (zh) *	2019-06-28	2025-04-15	宝洁公司	光增强处理方法
CN113005086B (zh) *	2021-02-01	2022-10-28	中国科学院遗传与发育生物学研究所	埃博霉素D和Apol8在调控神经干细胞定向神经元分化中的应用
KR102895904B1 (ko) *	2022-02-08	2025-12-04	주식회사 케이제이엠바이오	뇌기능 개선용 조성물의 제조방법 및 뇌기능 개선용 식품 및 약학적 조성물
CN115813841B (zh) *	2023-01-10	2023-09-05	广东迪美新材料科技有限公司	去屑止痒组合物及制备方法、应用，洗发水及制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008021970A2 (en) *	2006-08-09	2008-02-21	Reid William K	Treatment of motor neuron disease, including certain neurological disorders, motor neuropathies and chronic inflammatory diseases
US20090062244A1 (en) *	2007-09-04	2009-03-05	Joseph Schwarz	Pharmaceutical composition
US20100215775A1 (en) *	2006-10-20	2010-08-26	Symrise Gmbh & Co. Kg	Use of c10-c14-alkanediols in the preparation of a composition for the prophylaxis and/or treatment of malassezia-induced dandruff formation
US20100298394A1 (en) *	2007-04-05	2010-11-25	The Johns Hopkins University	Antifungal agents as neuroprotectants
US20110111014A1 (en) *	2007-06-26	2011-05-12	Parkinson's Institute	Methods and compositions for treatment of neurological disorders
CA2839350A1 (en) *	2011-07-05	2013-01-10	Contera Pharma Aps	The use of serotonin receptor agonists for treatment of movement disorders
WO2016079317A1 (en) *	2014-11-20	2016-05-26	Vib Vzw	Means and methods for treatment of early-onset parkinson's disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6495538B2 (en) *	1999-06-23	2002-12-17	Zinc Therapeutics, Canada Inc.	Zinc ionophores as therapeutic agents

2017
- 2017-12-13 JP JP2019551927A patent/JP2020502269A/ja active Pending
- 2017-12-13 MX MX2019007041A patent/MX2019007041A/es unknown
- 2017-12-13 CA CA3046501A patent/CA3046501A1/en not_active Abandoned
- 2017-12-13 CN CN201780086331.3A patent/CN110753543A/zh active Pending
- 2017-12-13 AU AU2017376458A patent/AU2017376458A1/en not_active Abandoned
- 2017-12-13 WO PCT/US2017/066218 patent/WO2018112106A1/en not_active Ceased
- 2017-12-13 EP EP17880499.3A patent/EP3554496A4/de not_active Withdrawn

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008021970A2 (en) *	2006-08-09	2008-02-21	Reid William K	Treatment of motor neuron disease, including certain neurological disorders, motor neuropathies and chronic inflammatory diseases
US20100215775A1 (en) *	2006-10-20	2010-08-26	Symrise Gmbh & Co. Kg	Use of c10-c14-alkanediols in the preparation of a composition for the prophylaxis and/or treatment of malassezia-induced dandruff formation
US20100298394A1 (en) *	2007-04-05	2010-11-25	The Johns Hopkins University	Antifungal agents as neuroprotectants
US20110111014A1 (en) *	2007-06-26	2011-05-12	Parkinson's Institute	Methods and compositions for treatment of neurological disorders
US20090062244A1 (en) *	2007-09-04	2009-03-05	Joseph Schwarz	Pharmaceutical composition
CA2839350A1 (en) *	2011-07-05	2013-01-10	Contera Pharma Aps	The use of serotonin receptor agonists for treatment of movement disorders
WO2016079317A1 (en) *	2014-11-20	2016-05-26	Vib Vzw	Means and methods for treatment of early-onset parkinson's disease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATRICK P. MICHEL ET AL: "Understanding Dopaminergic Cell Death Pathways in Parkinson Disease", NEURON, vol. 90, no. 4, 18 May 2016 (2016-05-18), US, pages 675 - 691, XP055425720, ISSN: 0896-6273, DOI: 10.1016/j.neuron.2016.03.038 *
VALENTINA S ARSIC ARSENIJEVIC ET AL: "A laboratory-based study on patients with Parkinson?s disease and seborrheic dermatitis: the presence and density of Malassezia yeasts, their different species and enzymes production", BMC DERMATOLOGY, BIOMED CENTRAL, LONDON, GB, vol. 14, no. 1, 14 March 2014 (2014-03-14), pages 5, XP021180748, ISSN: 1471-5945, DOI: 10.1186/1471-5945-14-5 *

Also Published As

Publication number	Publication date
EP3554496A1 (de)	2019-10-23
CN110753543A (zh)	2020-02-04
WO2018112106A1 (en)	2018-06-21
JP2020502269A (ja)	2020-01-23
MX2019007041A (es)	2022-09-09
AU2017376458A2 (en)	2019-08-01
CA3046501A1 (en)	2018-06-21
AU2017376458A1 (en)	2019-06-27

Legal Events

Date	Code	Title	Description
2018-06-23	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2019-09-20	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2019-09-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2019-10-23	17P	Request for examination filed	Effective date: 20190624
2019-10-23	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2019-10-23	AX	Request for extension of the european patent	Extension state: BA ME
2020-03-18	DAV	Request for validation of the european patent (deleted)
2020-03-18	DAX	Request for extension of the european patent (deleted)
2020-05-13	A4	Supplementary search report drawn up and despatched	Effective date: 20200415
2020-05-13	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 31/4174 20060101ALI20200407BHEP Ipc: A01N 43/40 20060101ALI20200407BHEP Ipc: A61K 33/14 20060101ALI20200407BHEP Ipc: A61P 25/16 20060101ALI20200407BHEP Ipc: A61K 31/4196 20060101ALI20200407BHEP Ipc: A61K 45/06 20060101ALI20200407BHEP Ipc: A61K 31/555 20060101ALI20200407BHEP Ipc: A61K 31/315 20060101AFI20200407BHEP Ipc: A61K 31/7048 20060101ALI20200407BHEP Ipc: A61K 31/203 20060101ALI20200407BHEP
2021-04-16	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2021-05-19	18D	Application deemed to be withdrawn	Effective date: 20201118

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