EP3631448A4 - Nachweis von par im liquor von patienten mit morbus parkinson - Google Patents

Nachweis von par im liquor von patienten mit morbus parkinson Download PDF

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Publication number
EP3631448A4
EP3631448A4 EP18810546.4A EP18810546A EP3631448A4 EP 3631448 A4 EP3631448 A4 EP 3631448A4 EP 18810546 A EP18810546 A EP 18810546A EP 3631448 A4 EP3631448 A4 EP 3631448A4
Authority
EP
European Patent Office
Prior art keywords
morbus
parkinson
par
liquor
patients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18810546.4A
Other languages
English (en)
French (fr)
Other versions
EP3631448A1 (de
Inventor
Ted Dawson
Valina DAWSON
Tae-In KAM
Liana ROSENTHAL
Shaida ANDRABI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Priority claimed from PCT/US2018/035614 external-priority patent/WO2018223003A1/en
Publication of EP3631448A1 publication Critical patent/EP3631448A1/de
Publication of EP3631448A4 publication Critical patent/EP3631448A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP18810546.4A 2017-06-02 2018-06-01 Nachweis von par im liquor von patienten mit morbus parkinson Withdrawn EP3631448A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762514316P 2017-06-02 2017-06-02
PCT/US2018/035614 WO2018223003A1 (en) 2017-06-02 2018-06-01 Detection of par in the csf of patients with parkinson's disease

Publications (2)

Publication Number Publication Date
EP3631448A1 EP3631448A1 (de) 2020-04-08
EP3631448A4 true EP3631448A4 (de) 2021-03-03

Family

ID=69669605

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18810546.4A Withdrawn EP3631448A4 (de) 2017-06-02 2018-06-01 Nachweis von par im liquor von patienten mit morbus parkinson

Country Status (2)

Country Link
EP (1) EP3631448A4 (de)
CN (1) CN110998321A (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113533725A (zh) * 2021-06-23 2021-10-22 上海市肺科医院 一种肺动脉高压的发病风险和预后标记物及其应用
CN115181798A (zh) * 2022-08-04 2022-10-14 中山大学 帕金森病认知障碍标志物及基于该标志物的疾病预测模型的构建方法与应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070292883A1 (en) * 2006-06-12 2007-12-20 Ossovskaya Valeria S Method of treating diseases with PARP inhibitors
WO2009152607A1 (en) * 2008-06-16 2009-12-23 Ottawa Hospital Research Institute Methods and kits for diagnosing neurodegenerative disease
US20130022982A1 (en) * 2009-09-14 2013-01-24 Kevin Ka-Wang Wang Micro-rna, autoantibody and protein markers for diagnosis of neuronal injury

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101661032A (zh) * 2008-08-29 2010-03-03 生物远景技术有限公司 帕金森病的生物标志物
US20170000836A1 (en) * 2013-05-22 2017-01-05 Sirbal Ltd. Prognostic and Diagnostic Methods and Herbal Therapies for Treating Skin Conditions, Autoimmune Diseases, Inflammatory Ailments and Cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070292883A1 (en) * 2006-06-12 2007-12-20 Ossovskaya Valeria S Method of treating diseases with PARP inhibitors
WO2009152607A1 (en) * 2008-06-16 2009-12-23 Ottawa Hospital Research Institute Methods and kits for diagnosing neurodegenerative disease
US20130022982A1 (en) * 2009-09-14 2013-01-24 Kevin Ka-Wang Wang Micro-rna, autoantibody and protein markers for diagnosis of neuronal injury

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2018223003A1 *

Also Published As

Publication number Publication date
CN110998321A (zh) 2020-04-10
EP3631448A1 (de) 2020-04-08

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