EP3720868A4 - Verbesserung der algenlipidproduktivität durch genetische modifikation eines signalproteins - Google Patents
Verbesserung der algenlipidproduktivität durch genetische modifikation eines signalproteins Download PDFInfo
- Publication number
- EP3720868A4 EP3720868A4 EP18884943.4A EP18884943A EP3720868A4 EP 3720868 A4 EP3720868 A4 EP 3720868A4 EP 18884943 A EP18884943 A EP 18884943A EP 3720868 A4 EP3720868 A4 EP 3720868A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- genetic modification
- signaling protein
- via genetic
- lipid productivity
- algal lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000012239 gene modification Methods 0.000 title 1
- 230000005017 genetic modification Effects 0.000 title 1
- 235000013617 genetically modified food Nutrition 0.000 title 1
- 150000002632 lipids Chemical class 0.000 title 1
- 102000034285 signal transducing proteins Human genes 0.000 title 1
- 108091006024 signal transducing proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762594930P | 2017-12-05 | 2017-12-05 | |
| PCT/US2018/063717 WO2019112982A1 (en) | 2017-12-05 | 2018-12-04 | Improving algal lipid productivity via genetic modification of a signaling protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3720868A1 EP3720868A1 (de) | 2020-10-14 |
| EP3720868A4 true EP3720868A4 (de) | 2021-12-22 |
Family
ID=66657878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP18884943.4A Withdrawn EP3720868A4 (de) | 2017-12-05 | 2018-12-04 | Verbesserung der algenlipidproduktivität durch genetische modifikation eines signalproteins |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11098328B2 (de) |
| EP (1) | EP3720868A4 (de) |
| JP (1) | JP2021505144A (de) |
| CN (1) | CN111433219A (de) |
| AU (1) | AU2018381232A1 (de) |
| BR (1) | BR112020010326A2 (de) |
| CA (1) | CA3093227A1 (de) |
| MX (1) | MX2020005784A (de) |
| WO (1) | WO2019112982A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2873198T3 (es) * | 2015-07-14 | 2021-11-03 | Synthetic Genomics Inc | Microorganismos que tienen un aumento en la productividad de lípidos |
| CN118028164B (zh) * | 2024-02-28 | 2024-10-25 | 广西壮族自治区农业科学院 | 一种钝化重金属镉菌株Cd05及应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012082731A2 (en) * | 2010-12-13 | 2012-06-21 | J. Craig Venter Institute | Engineered microalgae with enhanced lipid production |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090183270A1 (en) | 2002-10-02 | 2009-07-16 | Adams Thomas R | Transgenic plants with enhanced agronomic traits |
| WO2010138727A1 (en) * | 2009-05-27 | 2010-12-02 | Wisconsin Alumni Research Foundation | Cyanochrome fluorophores |
| WO2013005152A1 (en) * | 2011-07-05 | 2013-01-10 | Basf Plant Science Company Gmbh | Regulatory nucleic acid molecules for enhancing constitutive gene expression in plants |
| WO2013151665A2 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
| EP2840140B2 (de) * | 2012-12-12 | 2023-02-22 | The Broad Institute, Inc. | CRISPR-Cas verwendetes Verfahren zur Mutation von Prokaryonten |
| WO2015051342A2 (en) * | 2013-10-04 | 2015-04-09 | Synthetic Genomics, Inc. | Compositions and methods for modulating biomass productivity |
| US10351869B2 (en) * | 2015-09-04 | 2019-07-16 | Synthetic Genomics, Inc. | Microorganisms engineered for increased productivity |
-
2018
- 2018-12-04 JP JP2020530667A patent/JP2021505144A/ja active Pending
- 2018-12-04 BR BR112020010326-8A patent/BR112020010326A2/pt not_active IP Right Cessation
- 2018-12-04 CN CN201880078452.8A patent/CN111433219A/zh active Pending
- 2018-12-04 US US16/209,655 patent/US11098328B2/en not_active Expired - Fee Related
- 2018-12-04 MX MX2020005784A patent/MX2020005784A/es unknown
- 2018-12-04 CA CA3093227A patent/CA3093227A1/en active Pending
- 2018-12-04 AU AU2018381232A patent/AU2018381232A1/en not_active Abandoned
- 2018-12-04 WO PCT/US2018/063717 patent/WO2019112982A1/en not_active Ceased
- 2018-12-04 EP EP18884943.4A patent/EP3720868A4/de not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012082731A2 (en) * | 2010-12-13 | 2012-06-21 | J. Craig Venter Institute | Engineered microalgae with enhanced lipid production |
Non-Patent Citations (3)
| Title |
|---|
| IMAD AJJAWI ET AL: "Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator", NATURE BIOTECHNOLOGY, vol. 35, no. 7, 19 June 2017 (2017-06-19), New York, pages 647 - 652, XP055540971, ISSN: 1087-0156, DOI: 10.1038/nbt.3865 * |
| MICHIEL MATTHIJS ET AL: "Profiling of the Early Nitrogen Stress Response in the Diatom Phaeodactylum tricornutum Reveals a Novel Family of RING-Domain Transcription Factors", PLANT PHYSIOLOGY, vol. 170, no. 1, 18 November 2015 (2015-11-18), Rockville, Md, USA, pages 489 - 498, XP055615958, ISSN: 0032-0889, DOI: 10.1104/pp.15.01300 * |
| See also references of WO2019112982A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018381232A1 (en) | 2020-07-09 |
| EP3720868A1 (de) | 2020-10-14 |
| BR112020010326A2 (pt) | 2020-10-20 |
| JP2021505144A (ja) | 2021-02-18 |
| US20190169627A1 (en) | 2019-06-06 |
| MX2020005784A (es) | 2020-08-20 |
| WO2019112982A4 (en) | 2019-08-01 |
| CA3093227A1 (en) | 2019-06-13 |
| WO2019112982A1 (en) | 2019-06-13 |
| US11098328B2 (en) | 2021-08-24 |
| CN111433219A (zh) | 2020-07-17 |
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Legal Events
| Date | Code | Title | Description |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
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| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| 17P | Request for examination filed |
Effective date: 20200610 |
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| AK | Designated contracting states |
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| AX | Request for extension of the european patent |
Extension state: BA ME |
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| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20211124 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/44 20060101ALI20211118BHEP Ipc: C12N 15/63 20060101ALI20211118BHEP Ipc: C12N 15/10 20060101ALI20211118BHEP Ipc: C12N 9/22 20060101ALI20211118BHEP Ipc: C12N 9/16 20060101ALI20211118BHEP Ipc: C12N 1/36 20060101ALI20211118BHEP Ipc: C12N 1/12 20060101ALI20211118BHEP Ipc: C07K 14/405 20060101AFI20211118BHEP |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| 18W | Application withdrawn |
Effective date: 20230607 |