EP3764988A4 - Polypeptides de formation de gel - Google Patents

Polypeptides de formation de gel Download PDF

Info

Publication number: EP3764988A4
Authority: EP; European Patent Office
Prior art keywords: gel; forming polypeptides; polypeptides; forming
Prior art date: 2018-03-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

EP19768400.4A

Other languages

German (de)

English (en)

Other versions

EP3764988A1 (fr

Inventor

Sheau Yu Teddy Hsu

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Adepthera LLC

Original Assignee

Adepthera LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-03-15

Filing date

2019-03-14

Publication date

2022-04-20

2019-03-14 Application filed by Adepthera LLC filed Critical Adepthera LLC

2021-01-20 Publication of EP3764988A1 publication Critical patent/EP3764988A1/fr

2022-04-20 Publication of EP3764988A4 publication Critical patent/EP3764988A4/fr

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Inorganic Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP19768400.4A 2018-03-15 2019-03-14 Polypeptides de formation de gel Pending EP3764988A4 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201862643593P	2018-03-15	2018-03-15
PCT/US2019/022275 WO2019178359A1 (fr)	2018-03-15	2019-03-14	Polypeptides de formation de gel

Publications (2)

Publication Number	Publication Date
EP3764988A1 EP3764988A1 (fr)	2021-01-20
EP3764988A4 true EP3764988A4 (fr)	2022-04-20

Family

ID=67907279

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19768400.4A Pending EP3764988A4 (fr)	2018-03-15	2019-03-14	Polypeptides de formation de gel

Country Status (3)

Country	Link
EP (1)	EP3764988A4 (fr)
CN (2)	CN121421943A (fr)
WO (1)	WO2019178359A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL265109B2 (en)	2016-09-13	2024-05-01	Allergan Inc	Stabilized non-protein clostridial toxin compositions
CN110818790A (zh) *	2019-10-31	2020-02-21	成都圣诺生物制药有限公司	一种替莫瑞林的制备方法
CN113577014B (zh) *	2020-12-30	2023-03-24	广州图微科创生物科技有限公司	医疗器械、水凝胶及其制备方法与应用
US20240368354A1 (en) *	2021-08-27	2024-11-07	Defence Therapeutics Inc.	Steroid acid-based hydrogels
CN114181284B (zh) *	2021-11-17	2024-07-19	成都赛恩贝外科学研究院	纳米短肽drf3在药物、nk细胞载体和生物医学的应用
CN114214280B (zh) *	2021-12-20	2022-11-29	南开大学	一种利用自组装多肽衍生物水凝胶培养细胞球体的方法、一种细胞球体及其应用
CN115925975B (zh) *	2022-08-03	2024-09-17	山东大学	一种靶向肿瘤干细胞的car-mφ体内外编辑制备方法以及其应用
AU2023324667A1 (en)	2022-08-15	2025-02-13	Dana-Farber Cancer Institute, Inc.	Antibodies against cldn4 and methods of use thereof
CN120322258A (zh) *	2022-11-28	2025-07-15	爱德华兹生命科学公司	生物假体组织和假体抗微生物处理
CN116270974B (zh) *	2023-03-09	2024-03-12	湖南大学	一种组合物、阿柏西普递送系统和制备方法
CN117511851B (zh) *	2024-01-03	2024-03-26	中国肉类食品综合研究中心	水凝胶支架在细胞培育肉制备中的应用
CN118561959A (zh) *	2024-05-27	2024-08-30	上海市第一人民医院	一种多肽、用于抗衰老的透皮水凝胶及应用
CN119930747A (zh) *	2024-12-31	2025-05-06	上海市第一人民医院	一种多肽及其制成的水凝胶、以及在制备生物大分子药物透皮递送系统中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5958877A (en) *	1995-05-18	1999-09-28	Wimalawansa; Sunil J.	Method for counteracting vasospasms, ischemia, renal failure, and treating male impotence using calcitonin gene related peptide
US5998367A (en) *	1991-03-08	1999-12-07	Amylin Corporation	Pramlintide pro H-amylin salts and compositions
US20050261179A1 (en) *	2002-10-04	2005-11-24	The Government Of The United States Of America	Vasoregulating compounds and methods of their use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60327843D1 (de) *	2002-03-04	2009-07-16	Ipsen Pharma	Arzneimittelformulierungen mit verzögerter freisetzung mit einem trägerpeptid
CN108530543B (zh) *	2009-02-03	2023-06-23	阿穆尼克斯制药公司	延伸重组多肽和包含该延伸重组多肽的组合物
CN105079783B (zh) *	2014-05-22	2018-06-19	清华大学深圳研究生院	药物组合物及其制备方法和用途
DE102015000363A1 (de) *	2015-01-20	2016-07-21	Emc Microcollections Gmbh	Neue modular funktionalisierbare Peptid-Hydrogele
CN109475604B (zh) *	2016-02-09	2023-04-04	艾得佩索拉公司	长效型clr/ramp激动剂的配量和用途
CN107412150B (zh) *	2017-07-16	2019-07-09	常州大学	一种用于包裹药物的多肽水凝胶的制备方法

2019
- 2019-03-14 EP EP19768400.4A patent/EP3764988A4/fr active Pending
- 2019-03-14 CN CN202511547797.1A patent/CN121421943A/zh active Pending
- 2019-03-14 CN CN201980019009.8A patent/CN111885999A/zh active Pending
- 2019-03-14 WO PCT/US2019/022275 patent/WO2019178359A1/fr not_active Ceased

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5998367A (en) *	1991-03-08	1999-12-07	Amylin Corporation	Pramlintide pro H-amylin salts and compositions
US5958877A (en) *	1995-05-18	1999-09-28	Wimalawansa; Sunil J.	Method for counteracting vasospasms, ischemia, renal failure, and treating male impotence using calcitonin gene related peptide
US20050261179A1 (en) *	2002-10-04	2005-11-24	The Government Of The United States Of America	Vasoregulating compounds and methods of their use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ELGERSMA RONALD C. ET AL: "Synthesis and structural investigations of N-alkylated [beta]-peptidosulfonamide-peptide hybrids of the amyloidogenic amylin(20-29) sequence: implications of supramolecular folding for the design of peptide-based bionanomaterials", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 4, no. 19, 1 January 2006 (2006-01-01), pages 3587 - 3597, XP055866902, ISSN: 1477-0520, DOI: 10.1039/B606875H *
See also references of WO2019178359A1 *
SUTTER ET AL: "Recombinant gelatin hydrogels for the sustained release of proteins", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 119, no. 3, 22 May 2007 (2007-05-22), pages 301 - 312, XP022087330, ISSN: 0168-3659, DOI: 10.1016/J.JCONREL.2007.03.003 *

Also Published As

Publication number	Publication date
CN111885999A (zh)	2020-11-03
WO2019178359A1 (fr)	2019-09-19
CN121421943A (zh)	2026-01-30
EP3764988A1 (fr)	2021-01-20

Legal Events

Date	Code	Title	Description
2019-09-21	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2020-12-18	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2020-12-18	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2021-01-20	17P	Request for examination filed	Effective date: 20201012
2021-01-20	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2021-01-20	AX	Request for extension of the european patent	Extension state: BA ME
2021-06-23	DAV	Request for validation of the european patent (deleted)
2021-06-23	DAX	Request for extension of the european patent (deleted)
2022-01-19	RIC1	Information provided on ipc code assigned before grant	Ipc: C12P 21/02 20060101ALI20211215BHEP Ipc: A61K 47/42 20170101ALI20211215BHEP Ipc: A61K 38/16 20060101ALI20211215BHEP Ipc: A61K 9/06 20060101ALI20211215BHEP Ipc: A61K 9/00 20060101ALI20211215BHEP Ipc: C07K 7/06 20060101ALI20211215BHEP Ipc: C07K 14/47 20060101ALI20211215BHEP Ipc: C07K 14/585 20060101ALI20211215BHEP Ipc: C07K 14/575 20060101AFI20211215BHEP
2022-04-20	A4	Supplementary search report drawn up and despatched	Effective date: 20220321
2022-04-20	RIC1	Information provided on ipc code assigned before grant	Ipc: C12P 21/02 20060101ALI20220315BHEP Ipc: A61K 47/42 20170101ALI20220315BHEP Ipc: A61K 38/16 20060101ALI20220315BHEP Ipc: A61K 9/06 20060101ALI20220315BHEP Ipc: A61K 9/00 20060101ALI20220315BHEP Ipc: C07K 7/06 20060101ALI20220315BHEP Ipc: C07K 14/47 20060101ALI20220315BHEP Ipc: C07K 14/585 20060101ALI20220315BHEP Ipc: C07K 14/575 20060101AFI20220315BHEP

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