EP3810230A4 - Systeme und verfahren zur abgabe von wirkstoffen mit zwei komponenten - Google Patents

Systeme und verfahren zur abgabe von wirkstoffen mit zwei komponenten Download PDF

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Publication number
EP3810230A4
EP3810230A4 EP19823345.4A EP19823345A EP3810230A4 EP 3810230 A4 EP3810230 A4 EP 3810230A4 EP 19823345 A EP19823345 A EP 19823345A EP 3810230 A4 EP3810230 A4 EP 3810230A4
Authority
EP
European Patent Office
Prior art keywords
methods
drug delivery
delivery systems
component drug
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19823345.4A
Other languages
English (en)
French (fr)
Other versions
EP3810230A1 (de
Inventor
Marc Andrew Koska
Jay S. Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koska Family Ltd
Original Assignee
Koska Family Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/169,983 external-priority patent/US11382833B2/en
Application filed by Koska Family Ltd filed Critical Koska Family Ltd
Publication of EP3810230A1 publication Critical patent/EP3810230A1/de
Publication of EP3810230A4 publication Critical patent/EP3810230A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/02—Combined blow-moulding and manufacture of the preform or the parison
    • B29C49/04—Extrusion blow-moulding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42—Component parts, details or accessories; Auxiliary operations
    • B29C49/4273—Auxiliary operations after the blow-moulding operation not otherwise provided for
    • B29C49/428—Joining
    • B29C49/42802—Joining a closure or a sealing foil to the article or pincing the opening
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42—Component parts, details or accessories; Auxiliary operations
    • B29C49/4273—Auxiliary operations after the blow-moulding operation not otherwise provided for
    • B29C49/42808—Filling the article
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7158—Bottles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7544—Injection needles, syringes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP19823345.4A 2018-06-20 2019-06-20 Systeme und verfahren zur abgabe von wirkstoffen mit zwei komponenten Pending EP3810230A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862687340P 2018-06-20 2018-06-20
US16/169,983 US11382833B2 (en) 2016-04-25 2018-10-24 Systems and methods for fluid delivery
PCT/US2019/038302 WO2019246435A1 (en) 2018-06-20 2019-06-20 Systems and methods for dual-component drug agent delivery

Publications (2)

Publication Number Publication Date
EP3810230A1 EP3810230A1 (de) 2021-04-28
EP3810230A4 true EP3810230A4 (de) 2022-03-23

Family

ID=68984266

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19823345.4A Pending EP3810230A4 (de) 2018-06-20 2019-06-20 Systeme und verfahren zur abgabe von wirkstoffen mit zwei komponenten

Country Status (5)

Country Link
EP (1) EP3810230A4 (de)
JP (1) JP7489925B2 (de)
KR (1) KR102708626B1 (de)
CN (1) CN112543654B (de)
WO (1) WO2019246435A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018012967A (es) 2016-04-25 2019-03-06 Koska Family Ltd Sistema de suministro medico.
KR102639913B1 (ko) 2017-11-17 2024-02-23 코스카 패밀리 리미티드 유체 전달 매니폴드를 위한 시스템 및 방법
US12544511B2 (en) 2018-06-20 2026-02-10 Koska Family Limited Systems and methods for pre-filled dual-chamber medical agent delivery
EP4125585A2 (de) * 2020-03-31 2023-02-08 Preci Health SA Vorrichtung zur entnahme von körperflüssigkeiten und verfahren zur verwendung davon
CN115361983A (zh) * 2020-04-05 2022-11-18 科斯卡家族有限公司 用于预填充医疗输送装置的系统和方法
WO2021226564A1 (en) 2020-05-08 2021-11-11 Koska Family Limited Systems and methods for pre-filled multi-liquid medical delivery devices
USD1052082S1 (en) 2020-06-01 2024-11-19 Koska Family Limited Sealed fluid container
CN116018166B (zh) * 2020-07-30 2025-12-30 科斯卡家族有限公司 用于预填充医疗输送组件的系统和方法
CN116194387A (zh) * 2020-09-21 2023-05-30 奥罗菲诺制药集团责任有限公司 用于注射液体的可变形预包装设备
CN116634979A (zh) 2020-12-04 2023-08-22 科斯卡家族有限公司 用于预灌装药物输送组件的旋转穿刺的系统和方法
WO2022180488A1 (en) * 2021-02-26 2022-09-01 Koska Family Limited Pre-filled multi-fluid medical delivery assemblies
USD992110S1 (en) 2021-08-10 2023-07-11 Koska Family Limited Sealed fluid container
EP4392100B1 (de) * 2021-09-21 2025-07-23 Koska Family Limited Intradermales injektionssystem mit vorgefülltem blasfüllverschluss
CA3243172A1 (en) * 2022-01-18 2023-07-27 Credence Medsystems, Inc. MIXING AND INJECTION SYSTEM
CN116022466B (zh) * 2023-02-17 2026-02-10 常州富谦生物科技有限公司 一种隔离包装结构及其成型工艺

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140336610A1 (en) * 2013-04-09 2014-11-13 Biodel, Inc. Methods and devices for point of use mixing of pharmaceutical formulations
WO2017001925A1 (en) * 2015-07-02 2017-01-05 Marc Andrew Koska Single use delivery device prefilled with a reconstitutable agent
WO2017187262A1 (en) * 2016-04-25 2017-11-02 Marc Andrew Koska Medical delivery system

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5330426A (en) * 1992-08-13 1994-07-19 Science Incorporated Mixing and delivery syringe assembly
US7621887B2 (en) * 2000-10-10 2009-11-24 Meridian Medical Technologies, Inc. Wet/dry automatic injector assembly
JP2011508634A (ja) * 2007-12-28 2011-03-17 アクティヴパック， インコーポレイテッド 患者への治療剤の投与に適したディスペンサおよび治療用パッケージ
GB2461089B (en) * 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
AR076716A1 (es) * 2009-06-02 2011-06-29 Sanofi Aventis Deutschland Modulo medicado con medicamento de premezcla
JP2013542791A (ja) * 2010-11-03 2013-11-28 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイスのための薬用モジュール
US9265889B2 (en) * 2012-04-25 2016-02-23 Adar Medtech, Inc. Prefilled medical injection device
US9179260B2 (en) * 2012-12-03 2015-11-03 Mylan Inc. Medicament information system and method
AU2015331599B2 (en) * 2014-10-18 2020-11-05 Abbvie Inc. Wearable automatic injection system and apparatus
US9808608B2 (en) * 2014-11-16 2017-11-07 International Business Machines Corporation Helical coil delivery device for active agent
EP3031486A1 (de) * 2014-12-09 2016-06-15 CONARIS research institute AG Medikamentenkartuschen zur optimierten Dosierung
US20160175544A1 (en) * 2014-12-18 2016-06-23 Marc Andrew Koska Single use injection system
WO2017125859A2 (en) * 2016-01-20 2017-07-27 Appelbaum Nicholas Generating a dosing aid label for a syringe

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140336610A1 (en) * 2013-04-09 2014-11-13 Biodel, Inc. Methods and devices for point of use mixing of pharmaceutical formulations
WO2017001925A1 (en) * 2015-07-02 2017-01-05 Marc Andrew Koska Single use delivery device prefilled with a reconstitutable agent
WO2017187262A1 (en) * 2016-04-25 2017-11-02 Marc Andrew Koska Medical delivery system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2019246435A1 *

Also Published As

Publication number Publication date
CN112543654A (zh) 2021-03-23
KR20210049084A (ko) 2021-05-04
KR102708626B1 (ko) 2024-09-20
JP7489925B2 (ja) 2024-05-24
EP3810230A1 (de) 2021-04-28
WO2019246435A1 (en) 2019-12-26
CN112543654B (zh) 2024-01-05
JP2021527535A (ja) 2021-10-14

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