EP3846875A4 - System und verfahren zur entfernung von immuninhibitoren aus biologischen flüssigkeiten - Google Patents

System und verfahren zur entfernung von immuninhibitoren aus biologischen flüssigkeiten Download PDF

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Publication number
EP3846875A4
EP3846875A4 EP19920634.3A EP19920634A EP3846875A4 EP 3846875 A4 EP3846875 A4 EP 3846875A4 EP 19920634 A EP19920634 A EP 19920634A EP 3846875 A4 EP3846875 A4 EP 3846875A4
Authority
EP
European Patent Office
Prior art keywords
elimination
biological fluids
immune inhibitors
immune
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19920634.3A
Other languages
English (en)
French (fr)
Other versions
EP3846875A1 (de
Inventor
Steven Josephs
Matthew Ong
Amir Jafri
Robert Segal
Stephen Prince
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunicom Inc
Original Assignee
Immunicom Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunicom Inc filed Critical Immunicom Inc
Publication of EP3846875A1 publication Critical patent/EP3846875A1/de
Publication of EP3846875A4 publication Critical patent/EP3846875A4/de
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687—Chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • External Artificial Organs (AREA)
EP19920634.3A 2019-11-19 2019-11-19 System und verfahren zur entfernung von immuninhibitoren aus biologischen flüssigkeiten Withdrawn EP3846875A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2019/062177 WO2021101519A1 (en) 2019-11-19 2019-11-19 System and method for removal of immune inhibitors from biological fluids

Publications (2)

Publication Number Publication Date
EP3846875A1 EP3846875A1 (de) 2021-07-14
EP3846875A4 true EP3846875A4 (de) 2021-07-14

Family

ID=75980821

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19920634.3A Withdrawn EP3846875A4 (de) 2019-11-19 2019-11-19 System und verfahren zur entfernung von immuninhibitoren aus biologischen flüssigkeiten

Country Status (8)

Country Link
EP (1) EP3846875A4 (de)
JP (2) JP7159493B2 (de)
KR (2) KR102491518B1 (de)
CN (1) CN114650852B (de)
AU (3) AU2019474912B2 (de)
CA (2) CA3165330A1 (de)
IL (2) IL289438B2 (de)
WO (1) WO2021101519A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3194403A1 (en) * 2020-10-01 2022-04-07 Steven Josephs Reduced leaching of a ligand
US11224858B1 (en) 2020-10-01 2022-01-18 Immunicom, Inc. Reduced leaching of a ligand
JP7632141B2 (ja) * 2021-07-14 2025-02-19 東レ株式会社 モジュール

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140303542A1 (en) * 2013-03-14 2014-10-09 Brian J. LeBerthon Method and device for treating cancer
WO2018020285A2 (en) * 2016-07-28 2018-02-01 Captec Medical Kft. Flow capture device and method for removing cells from blood
US20190247560A1 (en) * 2018-02-13 2019-08-15 Gambro Lundia Ab Extracorporeal devices and methods of treating complement factor related diseases
WO2019167048A1 (en) * 2018-02-28 2019-09-06 Plas-free Ltd. Extracorporeal device and matrix for removing fibrinolytic proteins from biological fluids, methods and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3901216B2 (ja) 1995-02-16 2007-04-04 株式会社カネカ 腫瘍壊死因子−αの吸着剤、吸着除去方法および前記吸着剤を用いた吸着器
US8197430B1 (en) * 1998-05-22 2012-06-12 Biopheresis Technologies, Inc. Method and system to remove cytokine inhibitor in patients
JP4150838B2 (ja) 1999-11-02 2008-09-17 株式会社カネカ 充填物流出防止用フィルタ及びそれを装着した吸着器
EP1624785B1 (de) * 2003-01-17 2013-07-17 Aethlon Medical, Inc. Verfahren zur entfernung von viren aus dem blut durch lektin-affinitäts-hämodialyse
JP2006288571A (ja) * 2005-04-08 2006-10-26 Toray Ind Inc 癌治療用吸着材および体外循環カラム
JP4925159B2 (ja) * 2005-10-12 2012-04-25 日機装株式会社 血液浄化装置
BRPI0816165A2 (pt) * 2007-08-31 2015-02-24 Univ Michigan Dispositivo de citaferese seletiva e seus métodos relacionados
JP2009178523A (ja) * 2008-02-01 2009-08-13 Kaneka Corp 可溶性腫瘍壊死因子受容体の吸着材、吸着方法および吸着装置
JP5341559B2 (ja) * 2009-03-03 2013-11-13 和雄 寺本 多孔性吸着材
US9717841B2 (en) 2012-09-11 2017-08-01 Gary L. McNeil Closed-circuit device and methods for isolation, modification, and re-administration of specific constituents from a biological fluid source
WO2015130956A2 (en) 2014-02-28 2015-09-03 Exosome Sciences, Inc. Brain specific exosome based diagnostics and extracorporeal therapies
US10639405B2 (en) 2014-07-22 2020-05-05 Asahi Kasei Medical Co., Ltd. Adsorbent for removing histone and purification device for liquid derived from living organism
EP3274010B1 (de) * 2015-03-27 2019-10-02 Eliaz Therapeutics, Inc. Patientenselektive apherese
DE102018104177A1 (de) 2018-02-23 2019-08-29 B. Braun Avitum Ag Vorrichtung zur Entfernung von Noxen aus Blut, extrakorporales Perfusionssystem mit einer solchen Vorrichtung sowie Verfahren zur Herstellung einer solchen Vorrichtung

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140303542A1 (en) * 2013-03-14 2014-10-09 Brian J. LeBerthon Method and device for treating cancer
WO2018020285A2 (en) * 2016-07-28 2018-02-01 Captec Medical Kft. Flow capture device and method for removing cells from blood
US20190247560A1 (en) * 2018-02-13 2019-08-15 Gambro Lundia Ab Extracorporeal devices and methods of treating complement factor related diseases
WO2019167048A1 (en) * 2018-02-28 2019-09-06 Plas-free Ltd. Extracorporeal device and matrix for removing fibrinolytic proteins from biological fluids, methods and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2021101519A1 *

Also Published As

Publication number Publication date
IL289438B2 (en) 2023-09-01
EP3846875A1 (de) 2021-07-14
WO2021101519A1 (en) 2021-05-27
JP2023015053A (ja) 2023-01-31
KR102491518B1 (ko) 2023-01-20
IL289438A (en) 2022-02-01
CN114650852B (zh) 2024-08-06
JP7159493B2 (ja) 2022-10-24
AU2022203249A1 (en) 2022-06-23
CA3153685A1 (en) 2021-05-27
KR20220039724A (ko) 2022-03-29
AU2022203249B2 (en) 2023-08-31
AU2019474912B2 (en) 2022-02-17
JP7514281B2 (ja) 2024-07-10
AU2019474912A1 (en) 2022-01-06
KR20230016032A (ko) 2023-01-31
CA3153685C (en) 2022-10-11
IL289438B1 (en) 2023-05-01
JP2022535604A (ja) 2022-08-09
CA3165330A1 (en) 2021-05-27
CN114650852A (zh) 2022-06-21
AU2023274130A1 (en) 2023-12-21
IL301912A (en) 2023-06-01

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