EP3875575C0 - Mikrofluidchip und mikrofluidvorrichtung - Google Patents

Mikrofluidchip und mikrofluidvorrichtung

Info

Publication number: EP3875575C0
Authority: EP; European Patent Office
Prior art keywords: microfluid; chip; microfluid device; microfluid chip
Prior art date: 2018-10-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

EP19879796.1A

Other languages

English (en)

French (fr)

Other versions

EP3875575A4 (de

EP3875575A1 (de

EP3875575B1 (de

Inventor

Takumi Yoshitomi

Soohyeon Kim

Teruo Fujii

Mingyue Sun

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Nok Corp

The University of Tokyo

Original Assignee

Nok Corp

The University of Tokyo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-10-29

Filing date

2019-10-16

Publication date

2024-04-17

2019-10-16 Application filed by Nok Corp, The University of Tokyo filed Critical Nok Corp

2021-09-08 Publication of EP3875575A1 publication Critical patent/EP3875575A1/de

2022-01-26 Publication of EP3875575A4 publication Critical patent/EP3875575A4/de

2024-04-17 Application granted granted Critical

2024-04-17 Publication of EP3875575C0 publication Critical patent/EP3875575C0/de

2024-04-17 Publication of EP3875575B1 publication Critical patent/EP3875575B1/de

Status Active legal-status Critical Current

2039-10-16 Anticipated expiration legal-status Critical

Links

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/16—Microfluidic devices; Capillary tubes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/028—Modular arrangements
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0609—Holders integrated in container to position an object
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Dispersion Chemistry (AREA)
Clinical Laboratory Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Analytical Chemistry (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Sustainable Development (AREA)
Physics & Mathematics (AREA)
Fluid Mechanics (AREA)
Automatic Analysis And Handling Materials Therefor (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

EP19879796.1A 2018-10-29 2019-10-16 Mikrofluidchip und mikrofluidvorrichtung Active EP3875575B1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2018202991		2018-10-29
PCT/JP2019/040737 WO2020090481A1 (ja)	2018-10-29	2019-10-16	マイクロ流体チップおよびマイクロ流体デバイス

Publications (4)

Publication Number	Publication Date
EP3875575A1 EP3875575A1 (de)	2021-09-08
EP3875575A4 EP3875575A4 (de)	2022-01-26
EP3875575C0 true EP3875575C0 (de)	2024-04-17
EP3875575B1 EP3875575B1 (de)	2024-04-17

Family

ID=70464012

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19879796.1A Active EP3875575B1 (de)	2018-10-29	2019-10-16	Mikrofluidchip und mikrofluidvorrichtung

Country Status (5)

Country	Link
US (1)	US20210331163A1 (de)
EP (1)	EP3875575B1 (de)
JP (1)	JP7128492B2 (de)
CN (1)	CN112673090B (de)
WO (1)	WO2020090481A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2020090480A1 (ja) *	2018-10-29	2020-05-07	Nok株式会社	マイクロ流体チップおよびマイクロ流体デバイス
CN112673090B (zh) *	2018-10-29	2025-02-11	Nok株式会社	微流控芯片及微流控器件
US12508586B2 (en)	2020-06-30	2025-12-30	Plexium, Inc.	Uniform fluid flow with constant resistance and velocity
US11642675B2 (en) *	2020-06-30	2023-05-09	Plexium, Inc.	Fluidic device
CN119265034B (zh) *	2024-12-10	2025-04-15	山东富优生命科学有限公司	一种肿瘤类器官培养和药物实验的微流控装置及使用方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1327141A2 (de) *	2000-10-06	2003-07-16	Protasis Corporation	Fluidtrennungsleitungskassette
WO2004040295A1 (en) *	2002-10-31	2004-05-13	Nanostream, Inc.	Parallel detection chromatography systems
JP2005257283A (ja) *	2004-03-09	2005-09-22	Fluidware Technologies Kk	マイクロチップ
JP2006187684A (ja) *	2004-12-28	2006-07-20	Fuji Xerox Co Ltd	マイクロ流体素子
WO2012060186A1 (ja) *	2010-11-01	2012-05-10	コニカミノルタオプト株式会社	マイクロチップ、及び、マイクロチップの製造方法
CN102206573B (zh) *	2011-03-22	2014-12-31	博奥生物有限公司	用于微阵列芯片的自动进样装置及自动进样杂交微阵列芯片
JP6084370B2 (ja) *	2011-05-10	2017-02-22	国立大学法人東京大学	組織化学用自動反応装置
CN103769252B (zh) *	2012-10-18	2016-01-27	中国科学院深圳先进技术研究院	微流控芯片的连接器
CN104226385A (zh) *	2013-06-09	2014-12-24	北京百康芯生物科技有限公司	一种新型微流控芯片及其使用方法
WO2015063347A1 (es) *	2013-10-29	2015-05-07	Ikerlan, S. Coop.	Aparato para el control del caudal en un dispositivo microfluídico
CN103752356B (zh) *	2013-11-06	2015-08-12	山东省科学院海洋仪器仪表研究所	一种基于微流控芯片技术新型的镉柱还原系统及其加工方法
JP6272023B2 (ja) *	2013-12-26	2018-01-31	高砂電気工業株式会社	マイクロ流体チップ装置
KR101559050B1 (ko) *	2014-05-30	2015-10-12	한국과학기술원	기판에 구조물 삽입 방법 및 이를 사용하여 제조된 미세유체칩
CN204714811U (zh) *	2015-02-09	2015-10-21	张国豪	一种便携式核酸检测设备
US10976232B2 (en) *	2015-08-24	2021-04-13	Gpb Scientific, Inc.	Methods and devices for multi-step cell purification and concentration
CN105214747B (zh) *	2015-11-11	2017-05-10	东南大学	一种夹片式微流控器件及制造方法
CN105772125B (zh) *	2016-04-23	2018-09-21	北京化工大学	基于3d打印的微流控芯片夹具实验平台
CN107349979A (zh) *	2016-05-10	2017-11-17	李榕生	液流驱动用附加件易拆解的梅毒诊断用微流控装置
CN108148750B (zh) *	2016-12-05	2021-10-15	中国科学院大连化学物理研究所	一种原位形成拟胚体的多功能微流控芯片的制备方法
CN206804660U (zh) *	2017-06-26	2017-12-26	河北工业大学	一种基于微流控芯片的精子质量快速检测系统
JP6620269B2 (ja) *	2017-10-03	2019-12-11	Nok株式会社	細胞捕捉装置
CN108704681B (zh) *	2018-05-25	2021-10-01	辽宁工业大学	一种即插式微流控芯片稳固装置
CN109324174A (zh) *	2018-08-15	2019-02-12	杨东	一种即时健康方便易用的智能手机精子分析仪
WO2020090480A1 (ja) *	2018-10-29	2020-05-07	Nok株式会社	マイクロ流体チップおよびマイクロ流体デバイス
CN112673090B (zh) *	2018-10-29	2025-02-11	Nok株式会社	微流控芯片及微流控器件
CN215196994U (zh) *	2020-12-22	2021-12-17	广东工业大学	一种微流控芯片的固定结构

2019
- 2019-10-16 CN CN201980058572.6A patent/CN112673090B/zh active Active
- 2019-10-16 US US17/270,506 patent/US20210331163A1/en not_active Abandoned
- 2019-10-16 WO PCT/JP2019/040737 patent/WO2020090481A1/ja not_active Ceased
- 2019-10-16 JP JP2020553768A patent/JP7128492B2/ja active Active
- 2019-10-16 EP EP19879796.1A patent/EP3875575B1/de active Active

Also Published As

Publication number	Publication date
EP3875575A4 (de)	2022-01-26
CN112673090B (zh)	2025-02-11
CN112673090A (zh)	2021-04-16
WO2020090481A1 (ja)	2020-05-07
US20210331163A1 (en)	2021-10-28
JP7128492B2 (ja)	2022-08-31
EP3875575A1 (de)	2021-09-08
JPWO2020090481A1 (ja)	2021-09-02
EP3875575B1 (de)	2024-04-17

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